Clinical trials: Diabetes During Pregnancy
Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy
Effects of a Non-nutritive Sweetener Reduction Intervention in Pregnancy and Lactation on Maternal and Infant Outcomes
The effects of consuming non-nutritive sweeteners (NNS) during pregnancy and lactation on infant obesity and cardiometabolic disease risk are not well understood.
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Glucose Intolerance During Pregnancy, Non-nutritive Sweeteners Consumption in Pregnancy and/or Lactation
- Trial name
- NCT06548828
- Testing
- NNS Restriction Intervention, Control Intervention
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- George Washington University
Gestational Diabetes
Gestational Diabetes and Pharmacotherapy (GAP)
The goal of this study is to compare two different thresholds for initiation of medical treatment for GDM. Pregnant women diagnosed with GDM will be randomized to either start pharmacotherapy when they have reached at least 20%…
- Trial name
- GAP (NCT03527537)
- Testing
- Insulin
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- Medical College of Wisconsin
Non-Alcoholic Fatty Liver Disease
Ectopic Fat in Singaporean Women - the Culprit Leading to Gestational Diabetes, Metabolic Syndrome, and Type 2 Diabetes (TANGO Study)
Ectopic fat is the accumulation of adipose tissue in anatomical sites not classically associated with fat storage - for example, in the liver and skeletal muscles.
- Trial name
- TANGO (NCT05259475)
- Testing
- Lifestyle Advice, Diet Intervention, OCFA Meal-Based Diet-Intervention
- Where
- Singapore
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Chronic Kidney Diseases, Proteinuria
Efficacy of On-venous Laser Irradiation of Blood on Diabetes Kidney Disease Patients
The single center, randomized, assessor- and participant-blind, controlled, cross-over on-venous laser irradiation of blood clinical trial was performed to analyze patients with DKD.
- Conditions
- Chronic Kidney Diseases, Proteinuria, Diabetes Mellitus
- Trial name
- NCT06588465
- Testing
- On-venous Laser Irradiation of Blood, low dose On-venous Laser Irradiation of Blood
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Gestational Diabetes, Pregnancy Related
Gut and Oral Microbiome of GDM Patients During Pregnancy
The study aimed to clarify the characteristics of the intestinal and oral microbiome of Gestational Diabetes Mellitus(GDM) patients during the whole pregnancy, try to clarify the relationship between the microbiome and GDM.
- Trial name
- NCT04420507
- Where
- China
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Pregnancy - Prenatal Testing
GRAPE-GDM Prospective Comperative Trial - Grape Juice as a Replacement Drink for Gestational Diabetes Screening
Study Type: Observational, prospective, multicenter comparative study Primary Purpose: The goal of this study is to evaluate whether grape juice can serve as an effective alternative to the standard 50g glucola drink for…
- Trial name
- GRAPE-GDM (NCT07323901)
- Testing
- Participants will consume 500 ml of commercially available grape juice which contains 50g of sugar, serving as an alternative glucose load.
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Gestational Diabetes, Type2 Diabetes
Mobilizing Doulas to Empower Black Women in Post-partum Diabetes Prevention
Black and White mothers have similar prevalence of gestational diabetes mellitus (GDM). However Black mothers are more likely to develop Type 2 Diabetes Mellitus (T2DM) after a diagnosis of GDM.
- Trial name
- NCT04406792
- Testing
- DPP only, Diabetes Prevention Program (DPP) online + doula divas
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Gestational Diabetes
A Study Using Breath Tests to Identify Patients at Risk for Gestational Diabetes
The aim of our study is to evaluate the feasibility, and diagnostic value of oral 13C labelled glucose breath test compared to the GCT and OGTT tests.
- Trial name
- NCT07347262
- Testing
- Noninvasive Breath Test in Order to Identify Patients at Risk for Developing Gestational Diabetes
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Pregnancy Complications
Metformin Versus Insulin in Pregnant Women With Type 2 Diabetes
Pregnant women with type 2 diabetes mellitus (T2DM) are at increased risk for miscarriages, birth defects, large infants, and stillbirths. Maintaining blood sugars in the normal range decreases these pregnancy complications.
- Trial name
- NCT00678080
- Testing
- Metformin, Insulin (NPH and Regular)
- Where
- 3 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Gestational Diabetes Mellitus (GDM)
Screening for Dysglycemia During Postpartum Period in Women With GDM
Gestational diabetes mellitus (GDM) is one of the most common clinical conditions in pregnancy, with an increasing incidence due to the rise in overweight women and the postponement of motherhood.
- Trial name
- NCT07489456
- Testing
- Whatsapp message
- Where
- Brazil
- Volunteers
- 182 people
- Sponsor
- University of Sao Paulo General Hospital
Obesity, Pregnancy
Maternal Obesity, Breast Milk Composition, and Infant Growth
Today the majority of pregnant women in the United States are either overweight or obese at conception with their offspring having greater adiposity at birth, a 2-fold greater risk of later obesity, and neonatal insulin…
- Conditions
- Obesity, Pregnancy, Breastmilk Collection, Infant Overnutrition
- Trial name
- (MILK) (NCT03301753)
- Where
- 2 sites in United States
- Volunteers
- 2,050 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Gestational Diabetes Mellitus With Baby Delivered
Motivational Support and Meal Preparation Training to Reduce Vascular Risk After Gestational Diabetes
Women with a history of 'diabetes in pregnancy' or Gestational Diabetes (GDM) have a high risk for type 2 diabetes later in life.
- Trial name
- MoMM (NCT01814995)
- Testing
- Nutrition/Physical Activity Intervention
- Where
- 2 sites in Canada
- Volunteers
- 36 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Vitamin D Intake in First Trimester and Incidence of Gestational Diabetes Recurrence
Effect of Vitamin D Intake in Pregnancy to Prevent Recurrence of Gestational Diabetes
primary outcome is vitamin D intake in first trimester for pregnant women with history of gestational diabetes in previous pregnancies and incidence of gestational diabetes recurrence secondary outcome is effect of vitamin D…
- Trial name
- NCT03701087
- Testing
- Vitamin D
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Kasr El Aini Hospital
Gestational Diabetes, Controlled by Diet
Glucose Frequent of A1GDM in Labor
This is a prospective double arm study in patients with Gestational Diabetes Mellitus (GDM) utilizing frequent (single fingerstick on admission) vs infrequent glucose monitoring in labor (q 4 hours in latent labor and every 2…
- Trial name
- NCT06744621
- Testing
- Fingerstick
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gestational Diabetes
Pilot Study of Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes
This study is being done to study how exenatide, an FDA-approved drug that lowers blood sugar in non-pregnant patients with type II diabetes, works in pregnant women.
- Trial name
- NCT00572689
- Testing
- Exenatide, Buccal/blood Sample Collection
- Where
- 2 sites in United States
- Sponsor
- Georgetown University
Gestational Diabetes Mellitus in Pregnancy
Effectiveness of CGMS Vs. Self-monitoring Blood Glucose (SMBG) in Woman with Gestational Diabetes
The detection of and control of gestational diabetes carries benefits for both mother and baby related to immediate pregnancy outcomes.
- Trial name
- STEADYSUGAR (NCT04948112)
- Testing
- real time continuous glucose monitor, blinded continuous glucose monitor
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Woman's
Gestational Diabetes Mellitus (GDM)
Gamified Education for Diabetes Self-Management in GDM
Gestational diabetes mellitus (GDM) is a serious public health problem characterized by hyperglycemia that develops during pregnancy and causes significant short- and long-term health risks for both the mother and the fetus.
- Trial name
- NCT07067411
- Testing
- Education Program Using Gamification on GDM
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Yeditepe University
Gestational Diabetes, Pregestational Diabetes
Smartphone Utilization for Glucose Monitoring and Antenatal Reporting
This project will utilize MHealth technology to address the barriers providers and obstetric patients experience when reporting blood glucose results.
- Trial name
- SUGAR (NCT03504592)
- Testing
- Completion of Glucose logs
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Rochester
Gestational Diabetes, Glucose Metabolism Disorders
Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS)
This study aims to test the following hypotheses in a randomized controlled trial of post-partum women with a history of gestational diabetes mellitus (GDM) that will be followed up for up to 4 years: 1.
- Conditions
- Gestational Diabetes, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- I-HIPS (NCT05081037)
- Testing
- Wearable Care Group
- Where
- Singapore
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Vitamin D, Gestational Diabetes
Vitamin D Supplementation for the Prevention of GDM
This study was a double-blind multicenter randomized controlled study.
- Trial name
- NCT05208827
- Testing
- Vitamin D3
- Where
- China
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University