Clinical trials: Diabetes During Pregnancy
Gestational Diabetes Mellitus (GDM), Diabetes Type 2
Pregnancy and Postpartum Breastfeeding Support for Patients With Gestational Diabetes
The investigators will use implementation methods to develop better breastfeeding support for patients with gestational diabetes as a way to prevent type 2 diabetes.
- Conditions
- Gestational Diabetes Mellitus (GDM), Diabetes Type 2, Breastfeeding Continuation, Breastfeeding Support
- Trial name
- NCT07176793
- Testing
- Implementation mapping to develop a multilevel health system strategy for prevention of type 2 diabetes through targeted breastfeeding support for patients with gestational diabetes
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Gestational Diabetes Mellitus (GDM)
Validating CGM for GDM
This is a prospective pilot study to assess the validity of using a continuous glucose monitor (CGM) in diagnosing gestational diabetes mellitus (GDM).
- Trial name
- VALID (NCT06858787)
- Testing
- Continuous glucose monitor
- Where
- 3 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gestational Diabetes
Heterogeneity Informed Nutrition Therapy for Gestational Diabetes Mellitus
The hypothesis for this study is that women with different physiologic subtypes of gestational diabetes (GDM) (insulin secretion deficit vs.
- Trial name
- HINT-GDM (NCT04187521)
- Testing
- Meal A, Meal B
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Massachusetts General Hospital
Gestational Diabetes
Early Gestational Diabetes Mellitus
In 2010, the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) panel published consensus-based recommendations on the diagnosis and classification of hyperglycemia in pregnancy.
- Trial name
- LEMA_GDM (NCT04451915)
- Testing
- late management strategy, early management strategy
- Where
- 10 sites in France
- Volunteers
- 2,010 people
- Sponsor
- University Hospital, Lille
Hyperemesis Gravidarum - Severe, Resistin
First Trimester Resistin Levels in HG
This cross-sectional case-control study was conducted in Tuzla State Hospital Obstetrics Clinic in Turkey. The study evaluated 400 pregnant women during their first trimester of pregnancy.
- Conditions
- Hyperemesis Gravidarum - Severe, Resistin, Gestational Diabetes Mellitus (GDM)
- Trial name
- NCT06757374
- Testing
- Resistin
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Diabetes, Gestational, Menstrual Cycle Abnormal
Evaluation of Risk Factors for Gestational Diabetes Mellitus
This study examines the relationship between the age at menarche and gestational diabetes mellitus (GDM). In this retrospective study, the sample included all pregnant women diagnosed with GDM in a pregnancy polyclinic in…
- Trial name
- NCT04251559
- Testing
- oral glucose loading test
- Where
- Turkey (Türkiye)
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Obesity, Pregnancy
Determination of Maternal and Neonatal Apelinemia in Obese Women During Pregnancy
Background : Apelin and its receptor APJ have been implicated in pathologies including cardiovascular disease, diabetes and obesity. Little is known about the function of the apelinergic system during gestation.
- Conditions
- Obesity, Pregnancy, Gestational Diabetes
- Trial name
- OB-APE (NCT02796456)
- Testing
- blood sample
- Where
- France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Lille
Hyperemesis; Gravidarum, With Dehydration, Gestational Diabetes
Hyperemesis Gravidarum and 75 Gram Oral Glucose Tolerance Test
Hyperemesis gravidarum (HEG) is not only nausea and vomiting of pregnancy, but it is also a clinical syndrome including endocrine and metabolic complications.
- Trial name
- NCT02963753
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Gestational Diabetes
MOD Diet in Gestational Diabetes Mellitus
Gestational diabetes (GDM) is a condition of high blood glucose (or "blood sugar") during pregnancy. GDM can cause harmful short-term and long-term health effects for mom and baby.
- Trial name
- MOD (NCT04570111)
- Testing
- MOD Diet, Standard Care Diet
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Kansas Medical Center
Hypertension ,Pregnancy, Diabetes During Pregnancy
Impact of Exercise Prescription on Obstetric and Neonatal Outcomes
The aim of this study is to assess the impact of structured physical activity with smartwatch remote monitoring on glycemic control, blood pressure control, obstetric complications and neonatal outcomes in women with GDM, chronic…
- Conditions
- Hypertension ,Pregnancy, Diabetes During Pregnancy, Obesity (BMI>30)
- Trial name
- NCT07678944
- Testing
- Physical activity plan, Women who received information but did not engaged in a physical activity routine
- Where
- Portugal
- Volunteers
- 310 people
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Gestational Diabetes
Trimester Sequential Estimation of Serum Zonulin as a Predictor of Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) is the development of glucose intolerance (GI) during pregnancy in a previously normoglycemic (NG) woman and associated with insulin resistance (IR).
- Trial name
- NCT06336512
- Testing
- ELISA
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Benha University
Pregnancy Weight Gain, Postpartum Weight Retention
Pragmatic Randomized Clinical Trial to Limit Weight Gain in Pregnancy and Prevent Obesity
Healthy for Two, Healthy for You (H42/H4U) is an innovative evidence-based pregnancy/postpartum health coach intervention that is remotely-delivered (phone coaching using motivational interviewing, web-based platform, mobile…
- Conditions
- Pregnancy Weight Gain, Postpartum Weight Retention, Childhood Obesity, Gestational Diabetes
- Trial name
- H42/H4U (NCT04724330)
- Testing
- Healthy for Two/Healthy for You
- Where
- United States
- Volunteers
- 534 people
- Sponsor
- Johns Hopkins University
Gestational Diabetes, Type 2 Diabetes
Effects of a Lifestyle Intervention on Gestational Diabetes Management
The purpose of this study is to investigate the effects of nutrition education focusing on colorful fruit and vegetable intake with after-meal physical activity guidance on glycemic control and complications in women with…
- Conditions
- Gestational Diabetes, Type 2 Diabetes, Nutritional and Metabolic Disease
- Trial name
- NCT04861324
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Gestational Diabetes
The Acute Effect of Physical Activity on Postprandial Blood Glucose in Pregnant Women
The aim of the project is to investigate the acute effect of exercise on blood glucose after food consumption. Thereby the investigators wish to achieve knowledge that can improve prevention and treatment of gestational…
- Trial name
- NCT03641170
- Testing
- Physical activity, Inactivity, Fixed diet.
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diabetes, Gestational
Multicenter Randomized Trial of Non-inferiority Between Glyburide and Insulin for the Treatment of Gestational Diabetes
This clinical trial aims to test whether glibenclamide is non-inferior to insulin for the treatment of gestational diabetes.
- Trial name
- INDAO (NCT01731431)
- Testing
- Insulin, Glyburide
- Where
- France
- Volunteers
- 914 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes, Gestational
Acute Effects of Moderate Versus High Intensity Exercise on Insulin Sensitivity in Gestational Diabetes Mellitus
Exercise training is recognized as effective in preventing and treating many chronic metabolic disorders (1), and long-term exercise programmes have similar effects on glucose control as long-term drug or insulin therapy in type…
- Trial name
- GDMakutt (NCT01961401)
- Testing
- exercise
- Where
- Norway
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Diabetes, Gestational, Obesity
Maternal GDM in Hispanic Youth: Risk for Obesity
Our studies are aimed at examining effects of intrauterine exposure to GDM on metabolic risks in Hispanic children. Our primary hypothesis predicts that intrauterine exposure to GDM will be associated with one or more of three…
- Conditions
- Diabetes, Gestational, Obesity, Insulin Resistance, Insulin Secretion
- Trial name
- NCT02668601
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Gestational Diabetes, Diabetes Mellitus, Type 2
Decrease Type II Diabetes in Gestational Diabetes Population
The goal of the study is to examine the impact of an educational video on the rate of breastfeeding in mothers who had gestational diabetes mellitus, and the rate of type-II diabetes mellitus diagnosed postpartum.
- Conditions
- Gestational Diabetes, Diabetes Mellitus, Type 2, Breastfeeding, Diabetes Mellitus, Type 1
- Trial name
- NCT05202002
- Testing
- Video clip, No video clip
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Pregnancy
Gestational Diabetes: the Prevention
To assess the effectiveness of an exercise program developed during pregnancy (land/aquatic activities) aerobic and muscular tonification, on control to the prevention to Gestational Diabetes.
- Trial name
- NCT01790412
- Testing
- Exercise group
- Where
- Spain
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Technical University of Madrid
Heart Failure Preserved Ejection Fraction, Pregnancy Complications
Middle-aged Women With Adverse Pregnancy Outcomes and Heart Failure With Preserved Ejection Fraction
Due to the steady increase in the burden of HFpEF, especially in women, it is an important task to search for new markers and early predictors associated with the development of this disease.
- Trial name
- MAPO-HF (NCT06338943)
- Testing
- Echocardiography, Questionnaire
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine