Clinical trials: Diabetes During Pregnancy
Gestational Diabetes, Cardiovascular Diseases
Gestational Diabetes Mellitus: "Placental-maternal Crosstalk and Future Health"
The GaP study is designed to close important knowledge gaps by: 1. exploring placental health and cellular ageing in GDM and the association with neonatal outcome 2.
- Conditions
- Gestational Diabetes, Cardiovascular Diseases, Placenta Diseases
- Trial name
- GaP (NCT05872009)
- Where
- Norway
- Volunteers
- 350 people
- Sponsor
- Oslo University Hospital
Gestational Diabetes
The Use of Early Pregnancy HbA1c in Predicting Excessive Fetal Growth in Women at Risk of Glucose Intolerance
The association of hyperglycaemia in pregnancy (gestational diabetes mellitus; GDM) with adverse maternal and fetal outcomes is clearly recognised.
- Trial name
- SHAPE (NCT04858386)
- Where
- United Kingdom
- Volunteers
- 1,314 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Diabetes, Gestational, Postpartum Period
Gestational Diabetes Follow Up Study
The primary hypothesis underlying this proposal is that the introduction of a Promotora to provide education and proactive follow-up to women with GDM will increase compliance with postpartum glucose tolerance testing.
- Trial name
- NCT00998595
- Testing
- Promotora
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity, Gestational Diabetes
Impact of Diet and Exercise Activity on Pregnancy Outcomes
The general goal of the present study is to assess the impact of a community-based exercise and dietary intervention in pregnant women living in urban areas during and after their pregnancy on the reduction of the risks of both…
- Conditions
- Obesity, Gestational Diabetes, Type 2 Diabetes
- Trial name
- IDEA (NCT00486629)
- Testing
- Exercise and dietary education
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Macrosomia, Fetal, Gestational Diabetes Mellitus in Pregnancy
New Markers of Glycation to Predict Gestational Diabetes Mellitus and Macrosomia.
Gestational diabetes mellitus (GDM) increases the risk of macrosomia and other adverse pregnancy outcomes. Screening strategies are debated: universal vs.
- Trial name
- GLYCAGEST (NCT06048510)
- Testing
- Pregnant women
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Bordeaux
Fetal Cardiac Anomaly, Gestational Diabetes
Fetal Cardiac Remodeling in Gestational Diabetic Pregnancies at the Moment of Diagnosis
The aim of the present study will be to evaluate whether fetal cardiac remodeling is already present at the moment of the diagnosis of gestational diabetes (GD) in comparison with fetuses of healthy pregnant women.
- Trial name
- NCT05260931
- Testing
- Fetal echocardiography
- Where
- Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Gestational Diabetes
An RCT to Evaluate Incidence, Cost and Clinical Outcomes Using 75 vs 100g. Screening Methods for Gestational Diabetes
Diabetes in pregnancy or gestational diabetes (GDM) is a condition that, if left untreated, may lead to complications for the mother and her baby. It is still not known which is the best method to diagnosis GDM.
- Trial name
- NCT00295659
- Where
- Canada
- Volunteers
- 5,800 people, healthy volunteers welcome
- Sponsor
- Canadian Diabetes Association
Gestational Diabetes
The Use of Social Media Platform to Continuously Support Pregnant Women With Gestational Diabetes Mellitus
To assess the efficacy of utilizing a social media platform for dietary and lifestyle management in improving acceptance and blood glucose control in patients with gestational diabetes mellitus (GDM), compared to the control…
- Trial name
- NCT06292871
- Testing
- Additional GDM management through social media, Usual care
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- KK Women's and Children's Hospital
Type 2 Diabetes, Obesity
Long-term Effects of Lifestyle Intervention During Pregnancy in High Risk Women and in Their Offspring - Role of Environmental, Genetic and Epigenetic Factors
SUBJECTS: All participants in the RADIEL-study (2008-2011) who delivered (n=535), will be invited to this follow-up study, with their children (age 3-5 years) and the father.
- Conditions
- Type 2 Diabetes, Obesity, Metabolic Syndrome
- Trial name
- NCT02048839
- Where
- Finland
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Diabetes Mellitus, Type 2, Gestational Diabetes
Community Health Worker-Led Postpartum Diabetes Screening
Women who experience gestational diabetes are at high risk of developing type 2 diabetes mellitus in the postpartum period-especially in low- and middle-income countries like India where the burden of diabetes is high and…
- Trial name
- NCT06209411
- Testing
- Home Based Testing, Clinic Based Screening, Food order nutritional intervention before meals
- Where
- India
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Postpartum Urinary Incontinence, Postpartum Depression (PPD)
Prenatal Exercise Including Perineal Massage and Maternal-Neonatal Outcomes
The study is divided into three phases: Phase 1: Baseline survey to obtain an overall understanding of the current situation of voluntary participation in prenatal perineal massage.
- Conditions
- Postpartum Urinary Incontinence, Postpartum Depression (PPD), Neonatal Complications, Gestational Diabetes
- Trial name
- PEPM-RCT (NCT07314502)
- Testing
- Supervised prenatal exercise including antenatal perineal massage
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- South China Normal University
Vitamin D Deficiency, Obesity
D-tecting Disease - From Exposure to Vitamin D During Critical Periods of Life
Vitamin D deficiency is common among otherwise healthy pregnant women and may have consequences for them as well as the early development and long-term health of their children.
- Conditions
- Vitamin D Deficiency, Obesity, Diabetes Mellitus, Pre-Eclampsia
- Trial name
- D-tect (NCT03330301)
- Testing
- D-tect
- Where
- Denmark
- Volunteers
- 222,776 people
- Sponsor
- Bispebjerg Hospital
Gestational Diabetes, Hypoglycemia, Neonatal
Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled Trial
Pregnant women with gestational diabetes who are treated with insulin and their daily insulin dose is 30 IU or more will be randomized into two groups. Active treatment group will receive insulin-glucose-infusion during labour.
- Trial name
- NCT02590016
- Testing
- Insulin, Aspart
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Albuminuria
TreatIng Microalbuminuria Over 24 Weeks in Subjects With or Without Type 2 Diabetes or HYpertension
Rationale: Increased albuminuria has a relatively high prevalence in the general population (5-9%) People with increased albuminuria are more likely to develop progressive kidney and cardiovascular disease compared to persons…
- Trial name
- TIMOTHY (NCT05268926)
- Testing
- Dapagliflozin 10Mg Tab
- Where
- Netherlands
- Volunteers
- 9 people
- Sponsor
- University Medical Center Groningen
Gestational Diabetes Mellitus (GDM), Mindfulness
Effect of the Mindfulness-Based Stress Reduction Program on Prenatal Attachment, Distress and Anxiety Levels in Pregnant Women With Gestational Diabetes
This randomized controlled study aims to evaluate the potential effects of a mindfulness-based stress reduction (MBSR) program on prenatal attachment, distress, and anxiety levels among pregnant women diagnosed with gestational…
- Conditions
- Gestational Diabetes Mellitus (GDM), Mindfulness, Prenatal Attachment, Distress
- Trial name
- NCT06960109
- Testing
- A Mindfulness-Based Stress Reduction Program for Pregnant Women with Gestational Diabetes
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Type 2 Diabetes
Postpartum Screening of Type 2 Diabetes
Gestational diabetes mellitus (GDM) complicates 5 to 30 % of pregnancies. GDM is defined as hyperglycemia with onset or first recognition during pregnancy.
- Trial name
- Tot ou tard (NCT01869608)
- Testing
- oral glucose tolerance test 2 days post-partum
- Where
- Canada
- Volunteers
- 121 people
- Sponsor
- Université de Sherbrooke
Type 2 Diabetes, End Stage Renal Disease
Closed-loop in Adults With T2D Requiring Dialysis
The main objective of this study is to determine the efficacy, safety and utility of fully automated closed-loop glucose control in the home setting over a 20 day period in adults with type 2 diabetes (T2D) requiring maintenance…
- Trial name
- AP-Renal (NCT04025775)
- Testing
- CamAPS HX Closed-loop, Multiple Daily Insulin Injections (Control)
- Where
- 2 sites in Switzerland, United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Cambridge
Polycystic Ovary Syndrome, Miscarriage
The Effects of Metformin on Pregnancy and Miscarriage Rates in Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine whether metformin may improve pregnancy rates, and decrease miscarriage rates and complications of pregnancy, such as toxemia and gestational diabetes, in women with polycystic ovary…
- Conditions
- Polycystic Ovary Syndrome, Miscarriage, Infertility, Toxemia
- Trial name
- NCT00994812
- Testing
- metformin
- Where
- 5 sites in Finland
- Volunteers
- 326 people
- Sponsor
- University of Oulu
Gestational Diabetes
Diabetes Prevention in Women With a Recent History of Gestational Diabetes (Focus Groups)
The objective of this research is to conduct focus groups in order to adapt the Diabetes Prevention Program (DPP) so that it may successfully target women diagnosed with gestational diabetes (GDM) who are at high risk for…
- Trial name
- NCT01102530
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pregnancy, Gestational Diabetes
Role of Liver and Visceral Fat in Glucose and Lipid Metabolism During Pregnancy
Obesity, increased abdominal fat, fat stored in the liver, and insulin resistance may all be associated with adverse maternal and fetal pregnancy outcomes.
- Conditions
- Pregnancy, Gestational Diabetes, Obesity, Liver Fat
- Trial name
- NCT02282475
- Volunteers
- 78 people
- Sponsor
- Kaiser Permanente