Clinical trials: Diabetes During Pregnancy
Gestational Diabetes, Oxidative Stress
Prevention of Maternal and Fetal Metabolic Complications With Diet and Nutraceutical Supplementation in Pregnant Women Affected by Gestational Diabetes: a Randomized, Double-blind Placebo Controlled Trial.
Our trial aims to assess the effect of nutraceutical supplements (omega-3 fatty acids, anthocyanins and alpha-cyclodextrins) in patients affected by gestational diabetes.
- Trial name
- PREDIP2 (NCT05393843)
- Testing
- omega-3 fatty acids, anthocyanins and alpha-cyclodextrins, diet
- Where
- Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Diabetes, Gestational
Effect of Carbohydrate Distribution on Blood Glucose in Women With Gestational Diabetes Mellitus (GDM)
This study aims to investigate whether high-morning carbohydrate intake (HMK) compared with low-morning carbohydrate intake (LMK) affects glycemic variability in GDM patients based on Continuous glucose monitoring (CGM).
- Trial name
- NCT03835208
- Testing
- High/low carbohydrate distribution
- Where
- 2 sites in Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Pregnancy, Obesity
Nutrition and Pregnancy Intervention Study
A randomized double-blind placebo controlled intervention study with pregnant obese women (n=440) will be conducted. The intervention will involve consumption of fish oil and/or probiotic capsules from early pregnancy until 6…
- Conditions
- Pregnancy, Obesity, Gestational Diabetes Mellitus, Adiposity
- Trial name
- NCT01922791
- Where
- 2 sites in Finland
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Gestational Diabetes Mellitus
Humalog® Mix50/50(tm) as a Treatment for Gestational Diabetes
Evaluation of the Safety and Efficacy of Humalog® Mix50/50TM administered as 3 injections daily to Humalog® plus Humulin N® insulin administered as 6 separate injections daily in terms of glucose control for women with…
- Trial name
- NCT01613807
- Testing
- Insulin LISPRO, Insulin, Long-Acting and Insulin
- Volunteers
- 40 people
- Sponsor
- Sansum Diabetes Research Institute
Pregnant Women With Singleton Pregnancies
Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies
This is a randomized controlled trial to assess whether a personalized food kit to pregnant women is feasible, improves diet quality, and enhances pregnancy and birth outcomes compared to standard prenatal care.
- Trial name
- HH (NCT07659821)
- Testing
- Food Kit
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Vitamin D Intake in First Trimester and Incidence of Gestational Diabetes Recurrence
Effect of Vitamin D Intake in Pregnancy to Prevent Recurrence of Gestational Diabetes
primary outcome is vitamin D intake in first trimester for pregnant women with history of gestational diabetes in previous pregnancies and incidence of gestational diabetes recurrence secondary outcome is effect of vitamin D…
- Trial name
- NCT03701087
- Testing
- Vitamin D
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Kasr El Aini Hospital
Gestational Diabetes Mellitus (GDM), Type 2 Diabetes (T2DM)
Women With Previous GDM and the Effects of HIIT.
The goal of this clinical trial is to investigate if women with previous gestational diabetes (pGDM) are characterized with unique metabolic and molecular alterations compared to women without pGDM.
- Conditions
- Gestational Diabetes Mellitus (GDM), Type 2 Diabetes (T2DM), High-intensity Interval Training
- Trial name
- GDM-HIIT (NCT07566845)
- Testing
- High-intensity interval training
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Pregnancy Complications
Measuring sVAP-1 as a Predictor of Pregnancy Problems
Pre-eclampsia is a common pregnancy disorder defined as high blood pressure and protein in the urine after 20 weeks of pregnancy.
- Trial name
- NCT04891315
- Testing
- Blood test for soluble VAP-1 (sVAP-1).
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Gestational Diabetes
MTHFR Mutation and Concentration of B12,Folic Acid,Homocysteine and HS CRP in the Blood of Pregnant Women With GDM.
Research hypothesis: pregnant women with gestational diabetes have elevated serum CRP values and homocysteine compared to pregnant women with normal glucose metabolism Elevated CRP and homocysteine values are associated with…
- Trial name
- NCT04952324
- Testing
- Blood sampling and determination of MTHFR mutation,vitamin B12, folic acid, homocystein and HS CRP
- Where
- 2 sites in Bosnia and Herzegovina
- Volunteers
- 100 people
- Sponsor
- University of Mostar
Gestational Diabetes
Exercise in Pregnant Women With Gestational Diabetes
Gestational diabetes (GDM) impacts 1 in 10 pregnancies; hyperglycemia and hypertriglyceridemia are common features of the condition.
- Trial name
- NCT04145479
- Testing
- physical activity
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Oregon Health and Science University
Gestational Diabetes
Prevention of Gestational Diabetes
Pregnancy is a vulnerable period for both a mother and her developing child. The investigator hypothesizes that diet-induced glucose excursions in the pregnant mother are a key contributor to unfavourable brain development and…
- Trial name
- NuPreGDM (NCT04028089)
- Testing
- Diet Modification Group, Regular Diet Group
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Gestational Diabetes
The Effects of Resistance Exercises in Glycemic Control of Women With Gestational Diabetes
The object of this study is to evaluate patients with a diagnosis of GD who are included in a program of RE carried out with rubber tubes, comparing the frequency of women who will use insulin in the group who will participate in…
- Trial name
- NCT00815828
- Testing
- Resistance exercises
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- University of Sao Paulo
Gestational Diabetes Mellitus
Stratification of Risk of Diabetes in Early Pregnancy
Hyperglycaemia in Pregnancy or Gestational Diabetes Mellitus (GDM) is one of the most common obstetric medical conditions which when undetected can cause significant adverse outcomes for the mother and the offspring.
- Trial name
- STRiDE (NCT03005600)
- Where
- 2 sites in India, Kenya
- Volunteers
- 7,400 people, healthy volunteers welcome
- Sponsor
- University of Warwick
Gestational Diabetes Mellitus
Islet Function in Gestational Diabetes
The purpose of this research is to understand how the function of the human pancreas changes during and after pregnancy.
- Trial name
- NCT07806695
- Testing
- Exendin 9-39
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic
Non-Alcoholic Fatty Liver Disease
Ectopic Fat in Singaporean Women - the Culprit Leading to Gestational Diabetes, Metabolic Syndrome, and Type 2 Diabetes (TANGO Study)
Ectopic fat is the accumulation of adipose tissue in anatomical sites not classically associated with fat storage - for example, in the liver and skeletal muscles.
- Trial name
- TANGO (NCT05259475)
- Testing
- Lifestyle Advice, Diet Intervention, OCFA Meal-Based Diet-Intervention
- Where
- Singapore
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Pregnancy
Gestational Diabetes: the Prevention
To assess the effectiveness of an exercise program developed during pregnancy (land/aquatic activities) aerobic and muscular tonification, on control to the prevention to Gestational Diabetes.
- Trial name
- NCT01790412
- Testing
- Exercise group
- Where
- Spain
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Technical University of Madrid
Gestational Diabetes
Nutcracker: Can Almond Nut Consumption Improve Nocturnal Glycaemic Control in Women With Gestational Diabetes Mellitus?
Gestational diabetes, affecting over one in six births globally, is a growing public health concern. Characterised by high blood glucose, it increases the risk of pregnancy complications and raises the mother's long-term risk of…
- Trial name
- Nutcracker (NCT07069855)
- Testing
- Almond Snack Intervention for Gestational Diabetes
- Volunteers
- 156 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Gestational Diabetes, Type 2 Diabetes Mellitus
Mobile-based Lifestyle Intervention in Women With Glucose Intolerance After Gestational Diabetes
Although lifestyle modification programs have been shown to be effective in preventing diabetes in older populations, interventions in women with recent gestational diabetes (GDM) clearly need to be adapted to address their…
- Conditions
- Gestational Diabetes, Type 2 Diabetes Mellitus, Glucose Intolerance, Healthy Lifestyle
- Trial name
- MELINDA (NCT03559621)
- Testing
- mobile-based lifestyle intervention
- Where
- 7 sites in Belgium
- Volunteers
- 240 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hydronephrosis, Gestational Diabetes
Mild Fetal Hydronephrosis, Gestational Diabetes and Spontaneous Resolution vs Moderate-severe Fetal Hydronephrosis, Obstructive Causes and Worse Postnatal Outcome
Renal pelvis dilatation can be a relatively common finding on obstetric antenatal ultrasounds occurring in 1% to 5% of all pregnancies, with a known predilection for the male sex.
- Trial name
- FHYDO (NCT06896149)
- Testing
- Obstetric ultrasound
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gestational Diabetes, Pre-Eclampsia
Glucose and Blood Pressure During Pregnancy
The purpose of this research is to examine the beneficial effects of regular, non-invasive, glucose (sugar) assessment on glucose (sugar) and blood pressure regulation during pregnancy to help in predicting gestational diabetes…
- Conditions
- Gestational Diabetes, Pre-Eclampsia, Blood Pressure
- Trial name
- NCT04979312
- Testing
- LabClasp
- Where
- United States
- Sponsor
- Mayo Clinic