Clinical trials: Diabetes During Pregnancy
Gestational Diabetes Mellitus, Exercise
Moderate-to-vigorous Physical Activity for Glycemic Control in Patients With Gestational Diabetes Mellitus
Patients with newly diagnosed gestational diabetes will be recruited. The control group with get routine diet and exercise counseling.
- Trial name
- NCT01748305
- Testing
- Moderate-to-vigorous intensity exercise
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Type 1 Diabetes Mellitus, Pregnancy Related
Closed-loop Insulin Delivery In Type 1 Diabetes Pregnancies (CIRCUIT)
This trial will assess the efficacy of the Tandem t:slim X2 insulin pump with Control IQ technology compared with standard insulin delivery plus CGM in pregnant women with type 1 diabetes.
- Conditions
- Type 1 Diabetes Mellitus, Pregnancy Related, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- CIRCUIT (NCT04902378)
- Testing
- Tandem t:slim X2 insulin pump with Control IQ technology
- Where
- 14 sites in Australia, Canada
- Volunteers
- 94 people
- Sponsor
- University of Calgary
Gestational Diabetes, Obesity
Diabetes Prevention Strategies in Women With Gestational Diabetes Mellitus (GDM)
The main goal of this study is to examine the comparative effectiveness of diabetes prevention strategies in women with Gestational Diabetes Mellitus (GDM) on the control of the following conditions: obesity, hyperglycemia…
- Trial name
- NCT01344278
- Testing
- Lifestyle Counseling
- Where
- United States
- Volunteers
- 2,480 people
- Sponsor
- Kaiser Permanente
Diabetes in Pregnancy
Incentives and Glucose Adherence in Diabetes
Diabetes in pregnancy carries significant pregnancy specific risks and requires frequent glucose monitoring to reduce these risks.
- Trial name
- NCT03338829
- Testing
- Positive incentive, Loss aversion
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Pre-diabetes
Metformin and Sitagliptin in Women With Previous Gestational Diabetes
The goal of the present research is to compare the effects of treatment with metformin and sitagliptin, alone or in association, in women with previous gestational diabetes to evaluate the impact of the two drugs on beta-cell…
- Trial name
- NCT01336322
- Testing
- Metformin, Sitagliptin, Sitagliptin + Metformin
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pisa
Gestational Diabetes Mellitus in Pregnancy, Diabetes Self Management
Effect of Digital Storytelling Intervention on Diabetes Self-Management in Pregnant Women With Gestational Diabetes
The aim of this study is to evaluate the effect of digital storytelling intervention on diabetes self-management in women with gestational diabetes. It is a quasi-experimental study with a pretest-posttest control group.
- Trial name
- NCT06148688
- Testing
- Digital Story
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Izmir Katip Celebi University
Gestational Diabetes Mellitus in Pregnancy
Comparison of Metformin and Insulin for Management of Gestational Diabetes Mellitus
Gestational diabetic mellitus (GDM) patients randomised to metformin or insulin group.Aim was to achieve blood sugar levels of Blood sugar fasting (BSF) <5.3 mmol/l and 1 hour post meal<7.8mmol/l.
- Trial name
- NCT03320694
- Testing
- Metformin, Insulin
- Where
- Pakistan
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Type 2 Diabetes
Salt Intake and Antiproteinuric Effect of Paricalcitol in Type 2 Diabetes
Proteinuria is an independent risk factor for cardiovascular morbidity and mortality and for renal disease progression. More proteinuria is associated with faster progression, whereas treatments that reduce proteinuria are…
- Trial name
- PROCEED (NCT01393808)
- Testing
- Paricalcitol
- Where
- 6 sites in Italy
- Volunteers
- 112 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Gestational Diabetes
Immediate Postpartum Glucose Tolerance Testing
The objective of this study is to compare the accuracy of a 2hr glucose tolerance test administered during the postpartum hospitalization with the standard of care glucose tolerance testing (administered at 6 weeks postpartum).
- Trial name
- NCT04199676
- Testing
- Glucose tolerance test
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Diabetes Mellitus Pregnancy
Effect of Adding Metformin to Insulin in Uncontrolled Diabetic Patients During the 3rd Trimester of Pregnancy
Background Diabetes mellitus (DM) is a significant contributor to adverse obstetric and perinatal outcome. There is now clear and unequivocal evidence that adverse pregnancy outcomes are strongly linked to maternal hyperglycemia…
- Trial name
- NCT05479214
- Testing
- Metformin, Insulin
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Gestational Diabetes, Pregnancy
Integrating the Use of Calibration-Free Continuous Monitoring for Pregnancy Glucose Profiling: I-Profile Study
This study aims to test the following hypotheses in a longitudinal, observational study in pregnant women who will be randomized to received either a Blinded or Unblinded CGM sensor and followed-up 6-12 weeks after delivery: 1.
- Trial name
- I-Profile (NCT05123248)
- Testing
- Blinded Group, Unblinded group
- Where
- Singapore
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Gestational Diabetes
miRNA (microRNA) and FGF21 (Fibroblast Growth Factor-21) Profile in First Trimester and Gestational Diabetes Prediction
The goal of this observational study is to compare miRNA and FGF21 in pregnancy with and without GDM (Gestational Diabetes) The main question it aims to answer that miRNA and FGF21 are different between two groups.
- Trial name
- NCT05632055
- Testing
- blood draw
- Where
- Thailand
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Gestational Diabetes Mellitus, Pregnancy
GooDMoMS: A Multimodel Pregnancy and Postpartum Intervention for Gestational Diabetics
This study includes a behavioral educational intervention that focuses on healthy eating and physical activity during pregnancy and the postpartum among women newly diagnosed with gestational diabetes mellitus (GDM).
- Trial name
- NCT01600534
- Testing
- lifestyle counseling
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of North Carolina, Chapel Hill
Gestational Diabetes, Cardiovascular Diseases
Gestational Diabetes Mellitus: "Placental-maternal Crosstalk and Future Health"
The GaP study is designed to close important knowledge gaps by: 1. exploring placental health and cellular ageing in GDM and the association with neonatal outcome 2.
- Conditions
- Gestational Diabetes, Cardiovascular Diseases, Placenta Diseases
- Trial name
- GaP (NCT05872009)
- Where
- Norway
- Volunteers
- 350 people
- Sponsor
- Oslo University Hospital
Health Problems in Pregnancy, Pregnancy Outcomes
Peking University Birth Cohort in Weifang (PKUBC-WF)
The PKUBC-WF is a prospective cohort study carried out in Weifang city of Shandong, China. The primary aim of this study is to investigate the short-term and long-term effects of pre-pregnant and prenatal exposure on maternal and…
- Conditions
- Health Problems in Pregnancy, Pregnancy Outcomes, Gestational Diabetes, Gestational Hypertension
- Trial name
- NCT06234332
- Testing
- No Interventions
- Where
- China
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Peking University
Gestational Diabetes Mellitus as Antepartum Condition
Glycemic Impact of Myo-inositol in Pregnancy
Myo-inositol has been shown to decrease the rate of diabetes in pregnancy in European studies. It is not known exactly how this occurs or what it does to the sugar when the supplement is taken.
- Trial name
- NCT02149992
- Testing
- myo-inositol, Continuous glucose monitoring surveillance, Glucose monitoring
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Gestational Diabetes Mellitus
The Impact of Vitamin D Supplementation on Glucose Metabolism in Chinese Women With Former Gestational Diabetes Mellitus
Vitamin D deficiency are related to insulin resistance and impaired beta-cell function.It is reported that the level of vitamin D is lower during pregnancy and postpartum in the women with Gestational Diabetes Mellitus.
- Trial name
- NCT03138616
- Testing
- vitamin D
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Diabetes, Gestational Diabetes Mellitus
Walking Exercise and Nutrition to Reduce Diabetes Risk for You (WENDY)
The prevalence of Gestational Diabetes Mellitus (GDM) in Australia is approximately 5%-8%, with up to one third of all parous women who develop type 2 diabetes having a previous history of GDM.
- Trial name
- WENDY (NCT01247753)
- Testing
- Walking group
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Kidney Insufficiency, Diabetes Mellitus
Plant Versus Animal Dietary Protein and the Effect on Proteinuria
The purpose of this study is to investigate if a diet high in plant protein improves kidney function in patients with kidney insufficiency and diabetes and/or hypertension and/or glomerulonephritis.
- Conditions
- Kidney Insufficiency, Diabetes Mellitus, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
- Trial name
- NYPRO (NCT04058951)
- Testing
- High Animal Protein Diet (HAPD), High Plant Protein Diet (HPPD)
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Jens Rikardt Andersen
Metabolic Syndrome, Impaired Glucose Tolerance
Evaluation of Low Source of Signal in SCOUT DS
The overall objective of this study is to increase the number of dark skin tone individuals in the data set and evaluate if this increase in dark skin tone data has an impact on the accuracy of the SCOUT DS Diabetes Risk Score…
- Conditions
- Metabolic Syndrome, Impaired Glucose Tolerance, Gestational Diabetes
- Trial name
- LSS (NCT01339637)
- Where
- 5 sites in United States
- Volunteers
- 196 people
- Sponsor
- VeraLight, Inc.