Clinical trials: Diabetes During Pregnancy
Gestational Diabetes, GDM
The MalaYsian GestatiOnal Diabetes and Prevention of DiabetES Study
Gestational diabetes mellitus (GDM) is an increasingly common condition of pregnancy and is associated with adverse foetal, infant, and maternal outcomes.
- Conditions
- Gestational Diabetes, GDM, Pregnancy-Induced Diabetes
- Trial name
- MyGODDESS (NCT05204706)
- Testing
- MyManis app
- Where
- 3 sites in Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Diabetes During Pregnancy, Gestational Diabetes
Managing Diabetes in Pregnancy Using Cell Phone/Internet Technology
To compare compliance and satisfaction between a traditional method of blood glucose reporting using voicemail (control) and a novel method using cell phone /internet (Confidant) technology in the management of diabetic pregnant…
- Trial name
- NCT01907516
- Testing
- Cell phone-internet home glucose reporting system, Voicemail home blood glucose reporting
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hawaii Pacific Health
Diabetes Mellitus, Type 2
Comprehensive Postpartum Screening Strategies for Women With Gestational Diabetes Mellitus (GDM)
Previous gestational diabetes (GDM) predisposes affected women to diabetes. Pregnancy, in essence, serves as a metabolic stress test and uncovers underlying insulin resistance and ß-cell dysfunction.
- Trial name
- COPSS-GDM (NCT00849849)
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Woman's
Gestational Diabetes
The Use of Social Media Platform to Continuously Support Pregnant Women With Gestational Diabetes Mellitus
To assess the efficacy of utilizing a social media platform for dietary and lifestyle management in improving acceptance and blood glucose control in patients with gestational diabetes mellitus (GDM), compared to the control…
- Trial name
- NCT06292871
- Testing
- Additional GDM management through social media, Usual care
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- KK Women's and Children's Hospital
Gestational Diabetes
A Pilot Study Using Weightloss and Exercise to Prevent Recurring Gestational Diabetes in Obese Women
The purpose of this study is to examine the feasibility of recruiting and providing a behavioral weight loss program prior to pregnancy to reduce gestational diabetes recurrence.
- Trial name
- NCT00924599
- Testing
- Prevention of recurrent gestational diabetes through weight loss and exercise (English & Spanish), Lifestyle education (English & Spanish)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- California Polytechnic State University-San Luis Obispo
Pregnancy Related, Pregnancy Disease
Fetal Autonomic Nervous sysTem Evaluation
The autonomic nervous system (ANS) is involved in cardiovascular, metabolic and cognitive processes, so its study in the fetus can provide relevant functional diagnostic and prognostic information.
- Conditions
- Pregnancy Related, Pregnancy Disease, Pregnancy Complications, Pre-Eclampsia
- Trial name
- FANTE (NCT06330987)
- Testing
- electrocardiograph
- Where
- Italy
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Type 2 Diabetes
SWIFT: Study of Women, Infant Feeding and Type 2 Diabetes After GDM Pregnancy
The overall goal of the Study of Women, Infant Feeding and Type 2 Diabetes after GDM pregnancy (SWIFT) is to determine the relation of longer and more intensive lactation, as compared to formula feeding, on progression to…
- Trial name
- SWIFT (NCT01967030)
- Where
- United States
- Volunteers
- 1,035 people
- Sponsor
- Kaiser Permanente
Type 2 Diabetes
Metformin in Women With Type 2 Diabetes in Pregnancy Trial
Insulin is the standard treatment for the management of type 2 diabetes in pregnancy, however despite treatment with insulin, these women continue to face increased rates of adverse maternal and fetal outcomes.
- Trial name
- MiTy (NCT01353391)
- Testing
- Metformin
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Mount Sinai Hospital, Canada
Maternal Obesity Complicating Pregnancy, Birth,or Puerperium, Gestational Diabetes Mellitus
An Early-customized Low Glycaemic-index (GI) Diet Prevents LGA Babies in Overweight/Obese Pregnant Women
High pre-pregnancy body mass index (BMI) and excessive gestational weight gain (GWG) are associated with many unfavourable maternal and neonatal outcomes.
- Conditions
- Maternal Obesity Complicating Pregnancy, Birth,or Puerperium, Gestational Diabetes Mellitus, Birthweight, Large for Gestational Age (LGA)
- Trial name
- NCT02750774
- Testing
- Low-glycemic index group, Standard Care Group
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy
Treatment Satisfaction and Treatment Adherence of Diabetic Women Through the Use of FGM
The incidence of gestational diabetes mellitus (GDM), a glucose tolerance disorder during pregnancy, is increasing. In Germany, it reached 8.58 % in 2019. Standardized treatment has reduced complications for mother and child.
- Trial name
- Flash (NCT05924724)
- Testing
- Flash Glucose Monitoring
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Jena University Hospital
Small for Gestational Age at Delivery, Gestational Diabetes
The CanDo (Canadian Donor Milk) Trial
The goal of this clinical trial is to learn about the impact of donor milk vs formula supplementation on human milk feeding and the health outcomes of infants who require supplementation in well-baby units.
- Conditions
- Small for Gestational Age at Delivery, Gestational Diabetes, type1diabetes, Type2diabetes
- Trial name
- NCT06315127
- Testing
- Human donor milk, Formula
- Where
- 3 sites in Canada
- Volunteers
- 112 people
- Sponsor
- Mount Sinai Hospital, Canada
Gestational Diabetes
MTHFR Mutation and Concentration of B12,Folic Acid,Homocysteine and HS CRP in the Blood of Pregnant Women With GDM.
Research hypothesis: pregnant women with gestational diabetes have elevated serum CRP values and homocysteine compared to pregnant women with normal glucose metabolism Elevated CRP and homocysteine values are associated with…
- Trial name
- NCT04952324
- Testing
- Blood sampling and determination of MTHFR mutation,vitamin B12, folic acid, homocystein and HS CRP
- Where
- 2 sites in Bosnia and Herzegovina
- Volunteers
- 100 people
- Sponsor
- University of Mostar
Gestational Diabetes
Pregnancy Outcomes and Medical Costs According to Gestational Diabetes Mellitus Diagnostic Criteria
The aim of the study is to evaluate differences in pregnancy outcomes and medical costs depending on gestational diabetes diagnostic criteria used (one vs two-step approach).
- Trial name
- POMEC (NCT03421262)
- Testing
- IADPSG Criteria, NDDG Criteria
- Where
- Spain
- Volunteers
- 3,644 people, healthy volunteers welcome
- Sponsor
- Hospital Mutua de Terrassa
Gestational Diabetes Mellitus
Diagnosis Test for Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) is an asymptomatic disease. Diagnosis is based on a oral glucose tolerance test (OGTT) requiring pregnant women to absorb 75g of glucose while fasting since midnight and to stay sober for…
- Trial name
- NCT02482662
- Testing
- Diagnosis
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Université de Sherbrooke
Gestational Diabetes Mellitus in Pregnancy
Shear Wave Elastography in Gestational Diabetes Mellitus
Our aim was to investigate and compare placental elasticity by using Shear wave elastography (SWE) in patients with gestational diabetes mellitus (GDM) with and without insulin to non-diabetic controls.
- Trial name
- NCT04455880
- Testing
- SWE is a novel noninvasive dynamic ultrasound technique which refers to measurement for quantitative analysis of tissue elasticity
- Where
- Turkey (Türkiye)
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Gulsum Uysal
Type 2 Diabetes, Gestational Diabetes Mellitus
The Next Generation Longitudinal Birth Cohort Diabetes Study
The overall aim of this project is to understand the independent roles of maternal factors, intrauterine exposures, genetic factors, and postnatal environment on the development of obesity and youth-onset type 2 diabetes (T2D) in…
- Trial name
- NextGen (NCT04621396)
- Testing
- Observational screening study
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Gestational Diabetes
Fetal Cardiac Function Parameters and HbA1c As Screening for Gestational Diabetes Mellitus
This is a prospective cohort study to assess the predictive value of fetal cardiac parameters, the change in fetal cardiac parameters (CFP), HbA1c, and/or the change in HbA1c (ΔHbA1c) for gestational diabetes.
- Trial name
- NCT05019508
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Obesity, Polycystic Ovary Syndrome
Metformin and Gestational Diabetes in High-risk Patients: a RCTs
Gestational diabetes mellitus (DM) is one of the most frequent complications in pregnant patients with polycystic ovary syndrome (PCOS) in 20-40% of cases and ~40% of patients with gestational DM are likely to have underlying…
- Conditions
- Obesity, Polycystic Ovary Syndrome, Gestational Diabetes
- Trial name
- NCT00883259
- Testing
- Metformin
- Where
- 3 sites in Italy
- Volunteers
- 80 people
- Sponsor
- University Magna Graecia
Gestational Diabetes
Can Resveratrol Improve Insulin Sensitivity and Preserve Beta Cell Function Following Gestational Diabetes?
The purpose of this study is to determine if resveratrol supplementation preserves beta cell function and insulin sensitivity in post-partum women following a first diagnosis of gestational diabetes.
- Trial name
- NCT01997762
- Testing
- Resveratrol
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Gestational Diabetes Mellitus in Pregnancy
Effects of Chewing Gum on Glycaemic Control in Women With Gestational Diabetes
This study aims to assess the impact of enhanced chewing on glycaemic control in females with newly diagnosed GDM. It is hypothesised, that a fixed amount of gum chewed for 20 minutes before starting each meal could improve…
- Trial name
- NCT03961542
- Testing
- Chewing
- Where
- Austria
- Volunteers
- 74 people
- Sponsor
- Medical University of Vienna