Clinical trials: Diabetes Insipidus
Healthy
The Effects of Oral Vasopressin on Attention Control: An Eye-tracking Study
The main aim of the present study is to investigate the effects of orally administered vasopressin (AVP) on bottom-up and top-down attentional control to socio-emotional stimuli by combining a validated saccade/antisaccade…
- Trial name
- NCT06329037
- Testing
- Vasopressin
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Hypotension
Effects of Ephedrine, Phenylephrine, Norepinephrine and Vasopressin on Contractility of Human Myometrium and Umbilical Vessels: An In-vitro Study
Hypotension is one of the most common adverse effects of spinal anesthesia for cesarean deliveries, affecting as many as 55-90% of mothers.
- Trial name
- NCT04053478
- Testing
- Ephedrine, Phenylephrine, Norepinephrine
- Where
- Canada
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Stress
Copeptin During a Standardized Psychological Stress Test
The aim of the PsyCo Study is to determine whether psychological Stress has an influence on copeptin levels.
- Trial name
- PsyCo (NCT01866137)
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy
The Effects of Oxytocin and Vasopressin on Delta-beta Cross-frequency Coupling
The main aim of the study is to investigate whether intranasal oxytocin and vasopressin have effects on delta-beta cross-frequency coupling under resting-state and task conditions.
- Trial name
- NCT06605300
- Testing
- Intranasal Oxytocin (IN-OXT), Intranasal Vasopressin (AVP)
- Where
- 2 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Excess Intake of Macronutrients, Excess Intake of Micronutrients
Water and Coffee Intervention in Humans
39 healthy subjects without medication (except oral contraceptives) aged 20-70 years are recruited via advertisements or through telephone contacts with individuals that had previously participated in population-based cohort…
- Conditions
- Excess Intake of Macronutrients, Excess Intake of Micronutrients, Vasopressin Low
- Trial name
- NCT06165185
- Testing
- Water, Coffee, Control
- Where
- Sweden
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Region Skane
Insulin Resistance
The Effect of Vasopressin on Glucose Regulation
Data from experimental animals and human epidemiological studies have suggested that hypohydration and/or low water intake is linked to poor glucose regulation and diabetes.
- Trial name
- HYPERGlu (NCT02761434)
- Testing
- Hypertonic Saline (3% NaCl), Isotonic Saline (0.9% NaCl)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
Polyuria, Polydipsia
Copeptin in Differentiation of Polyuria and Polydipsia
The differential diagnosis of patients with polyuria/ polydipsia is often complex, but important for the therapeutic strategy. Challenging is in particular the clinical differentiation between patients with a partial Diabetes…
- Trial name
- NCT01056887
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Healthy
Vasopressin Effects on Human Social Communication
This research is being done because we wish to understand how a chemical produced in the brain, vasopressin, effects emotional social communication processes.
- Trial name
- AVP (NCT01327027)
- Testing
- Vasopressin, Arginine, ADH
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Bowdoin College
Healthy, Polyuria-polydipsia Syndrome
Copeptin After Arginine Infusion in Polyuria-Polydipsia Syndrome
the purpose of the study is to investigate whether arginine infusion is a new tool to differentiate patients with diabetes insipidus, primary polydipsia and healthy subjects.
- Trial name
- NCT01879137
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Hyponatremia
Subclassification of the Syndrome of Inappropriate ADH Secretion
The aim of this study is to evaluate the different types of osmotic dysregulation in patients with Syndrome of Inappropriate ADH (SIADH) and, hence, to analyze the pathophysiology of SIADH.
- Trial name
- NCT01341665
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Healthy
Effects of Intranasal Oxytocin and Vasopressin on Social Behavior
The purpose of this study is to investigate the role of a one-time intranasal administration of the oxytocin, vasopressin, or placebo on prosocial decision making such as cooperation and altruism in a healthy population of…
- Trial name
- NCT01296269
- Testing
- Oxytocin, Arginine Vasopressin
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Central Diabetes Insipidus
Plasma Oxytocin Changes in Response to Low-dose MDMA vs. Placebo in Patients With Arginine Vasopressin Deficiency and Healthy Controls
The investigator hypothesize that low-dose MDMA (3,4-methylenedioxymethamphetamine) will produce a sufficiently strong oxytocin stimulation in healthy controls and no relevant increase in patients.
- Trial name
- OxyMAX (NCT06789705)
- Testing
- MDMA
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
ADHD, ADD
ADHD Electrophysiological Subtypes and Implications in Transcranial Direct-current Stimulation
In the present study the aim is to examine whether transcranial direct-current stimulation (tDCS) generated excitability changes and induce modifications of functional cortical architecture in Attention Deficit Hyperactivity…
- Trial name
- tdcs&adhd (NCT01649232)
- Testing
- Active tDCS
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Spanish Foundation for Neurometrics Development
Endotoxemia
Effects of Vasopressors on Immune Response
Noradrenaline is a catecholamine and the cornerstone treatment for the improvement of hemodynamic parameters in septic shock. Catecholamines exert profound immunomodulatory effects.
- Trial name
- NCT02675868
- Testing
- Norepinephrine, Phenylephrine, Vasopressins
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Diabetes Mellitus, Type 1, Monogenic Diabetes
Monogenic Diabetes Misdiagnosed as Type 1
The study has two aims: 1. To (1a) determine the frequency of monogenic diabetes misdiagnosed as type 1 diabetes (T1D) and (2) to define an algorithm for case selection. 2.
- Conditions
- Diabetes Mellitus, Type 1, Monogenic Diabetes, Neonatal Diabetes, Maturity-onset Diabetes in the Young (MODY)
- Trial name
- ADDAM (NCT03988764)
- Testing
- None AHT
- Where
- Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Healthy Adults, Copeptin
Copeptin Changes After Food Intake
The purpose of this study is to determine whether copeptin levels are affected by food intake.
- Trial name
- CoMeal (NCT01772914)
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Pregnancy, Stress
Effects of Stress on Glucose Tolerance During Pregnancy
The objective of the study is to investigate the effect of stress on glucose tolerance during pregnancy. The main objectives of the study are to investigate if various measures of stress (stressful life events, the perceived…
- Conditions
- Pregnancy, Stress, Gestational Diabetes
- Trial name
- NCT01707784
- Where
- Switzerland
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Sonic Augmentation Technology
Plasma Oxytocin Changes in Response to Music Modified by Sonic Augmentation Technology
The investigator aim to investigate wheather music modified by sonic augmentation technology can produce increasing oxytocin levels with minimal to no side effects in a highly standardized setting
- Trial name
- TechnOXY (NCT07276152)
- Testing
- sonic augmentation technology
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Autism Spectrum Disorders
Brain Imaging Study of Adults With Autism Spectrum Disorders
This research study investigates the effects of oxytocin and vasopressin on brain activity in adults with Autism Spectrum Disorders using functional magnetic resonance imaging (fMRI).
- Trial name
- NCT01093768
- Testing
- Oxytocin, Vasopressin
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)