Clinical trials: Diabetes Mellitus II
Type 2 Diabetes Mellitus
Trial to Evaluate the Efficacy on Glycemic Variability and Safety of Gemigliptin Compared With Dapagliflozin Added on Metformin Alone or Diabetes Medication Naïve Patient in Type 2 Diabetes Mellitus (Stable II Study)
The objective of this study is to evaluate the efficacy on glycemic variability and safety of gemigliptin 50 mg orally administered once daily for 12 weeks compared with Dapagliflozin 10mg in patients with type 2 diabetes…
- Trial name
- NCT03202563
- Testing
- Gemigliptin 50mg, Dapagliflozin 10mg, Diet/exercise questionnaire
- Where
- South Korea
- Volunteers
- 71 people
- Sponsor
- LG Chem
Type II Diabetes Mellitus
Effects of Krill Oil on Endothelial Function in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the effects of krill oil supplementation in patients with Type 2 diabetes mellitus on heart health and laboratory diabetic measurements.
- Trial name
- NCT02091193
- Testing
- Krill Oil (Supplement A)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Danbury Hospital
Diabetic Nephropathies, Diabetes Mellitus, Type II
Environmental Exposure to Lead and Progressive Renal Insufficiency in Type II Diabetic Nephropathy
Background The relationship between long-term heavy lead exposure and chronic interstitial nephropathy is well recognized in the previous literatures.
- Trial name
- NCT00237952
- Testing
- EDTA chelating agents
- Where
- 2 sites in China
- Sponsor
- Chang Gung Memorial Hospital
Type II Diabetes Mellitus
A Clinical Trial to Evaluate the Food Effect of CKD-379
A clinical trial to evaluate the food effect of CKD-379
- Trial name
- CKD-379 (NCT06652971)
- Testing
- CKD-379
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Foot Ulcer, Diabetic
Use of Procenta® Conformable Barrier for Non-Healing Foot & Ankle Ulcers in Patients With Diabetes Mellitus Types I and II
Procenta® has been successful in facilitating closure of non-healing diabetic ulcers in patients where proper wound care management/practice has failed along with other allo- and xenografts.
- Trial name
- Procenta (NCT05099887)
- Testing
- Procenta conformable barrier
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The VA Western New York Healthcare System
Type 1 Diabetes Mellitus
Safety and Efficacy of Autologous Adipose-Derived Stem Cell Transplantation in Patients With Type 1 Diabetes
The purpose of this study is to determine whether intravenous administration of autologous adipose stem cells is safe and beneficial in patients with type 1 diabetes.
- Trial name
- NCT00703599
- Testing
- Autologous Adipose-derived Stem cells
- Where
- 2 sites in Philippines
- Volunteers
- 30 people
- Sponsor
- Adistem Ltd
Diabetes Mellitus, Type 2
Performance Under SGLT-2-Inhibitors in Humans
The PUSH Study is conceived to investigate the early effects of SGLT-2-Inhibitors on the physical performance of patients with Type-II-Diabetes mellitus compared to patients under other therapy regimes.
- Trial name
- PUSH (NCT03422263)
- Where
- Switzerland
- Volunteers
- 450 people
- Sponsor
- Berner Klinik Montana
Diabetic Foot Ulcer
Blue Light Photobiomodulation Therapy on Neuroischemic Patients
This is a pilot case/control clinical study on a group of outpatients with diabetic foot lesions aiming to verify the efficacy and safety of the Blue light photobiomodulation therapy with EmoLED medical device, in addition to…
- Trial name
- HERMES (NCT04831606)
- Testing
- debridement, Offloading, Advanced dressing
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Emoled
Renal Disorder Associated With Type II Diabetes Mellitus
Type 2 Diabetes Mellitus and Chronic Kidney Disease
To investigate the effect of co existance of diabetes mellitus and chronic kidney disease on basic coagulation profile in comparison with diabetic patients with normal kidney function and non diabetic patients with chronic kidney…
- Trial name
- NCT04971252
- Testing
- Hematologic tests for patients with diabetes mellitus and chronic kidney disease
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Cardiovascular Disease, Diabetes
Canola Oil Multi-Centre Intervention Trial II
The objectives of the study are to examine the health benefits of dietary canola oils on body composition, specifically on android fat, and weight management.
- Conditions
- Cardiovascular Disease, Diabetes, Metabolic Syndrome
- Trial name
- COMIT2 (NCT02029833)
- Testing
- Regular Canola Oil, High Oleic Canola Oil, Western Type Diet - Common Dietary Oils
- Where
- 4 sites in United States, Canada
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Atherosclerotic Cardiovascular Disease, Symptomatic Atherosclerosis
An Extension Trial of Inclisiran in Participants With Cardiovascular Disease and High Cholesterol
This clinical study was designed to assess the efficacy, safety, and tolerability of long-term dosing of inclisiran and evolocumab given as subcutaneous injections in participants with high cardiovascular risk and elevated…
- Conditions
- Atherosclerotic Cardiovascular Disease, Symptomatic Atherosclerosis, Type2 Diabetes, Familial Hypercholesterolemia
- Trial name
- ORION-3 (NCT03060577)
- Testing
- Inclisiran, Evolocumab
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 382 people
- Sponsor
- Novartis Pharmaceuticals
Type2 Diabetes Mellitus
A Phase 2 Study of DS-8500a in Japanese Subjects With Type 2 Diabetes Mellitus (T2DM)
The objectives of the study is to evaluate the efficacy, safety, and dose of DS-8500a compared with placebo in patients with type 2 diabetes mellitus.
- Trial name
- NCT02628392
- Testing
- DS-8500a, Sitagliptin
- Where
- Japan
- Volunteers
- 368 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Diabetes Mellitus, Type 2
Hartmann's Solution and Normal Saline in Type II Diabetes Patients
The purpose of this study is to determine whether perioperative use of Hartmann's solution in type II diabetes patients increases blood glucose level after surgery.
- Trial name
- NCT02305199
- Testing
- Hartmann's solution, Normal saline
- Where
- South Korea
- Sponsor
- Yeungnam University College of Medicine
Diabetes Mellitus, Type II
Mechanisms of Glycemic Improvement After Gastrointestinal Surgery
This study is designed as a prospective clinical trial aimed at investigating the mechanisms behind observed improvements in type 2 diabetes mellitus (T2DM) following bariatric surgery.
- Trial name
- NCT01025999
- Testing
- No intervention
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Washington
Overweight and Obesity
A Trial to Learn How Safe AZD9550 Monotherapy and Combined With AZD6234 is in People With or Without Type 2 Diabetes Who Are Living With Obesity and Overweight
AZD9550, previously being developed for the treatment NASH, is a dual GCG and GLP-1 receptor agonist. AZD9550 is now being developed in combination with AZD6234, a SARA, for the treatment of overweight and obesity and its…
- Trial name
- CONTEMPO (NCT06151964)
- Testing
- AZD9550, AZD9550 and AZD6234
- Where
- 15 sites in Austria, Canada and 3 more
- Volunteers
- 166 people
- Sponsor
- AstraZeneca
Endocrine System Diseases
Diabetic Treatment Adherence
The goal of this clinical research study is to test an investigational type of packaging for diabetes drugs called "unit-dose packaging." Researchers want to learn if unit-dose packaging can help patients with Type II diabetes to…
- Trial name
- NCT01318564
- Testing
- Metformin, Questionnaires
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- M.D. Anderson Cancer Center
Type 2 Diabetes Mellitus
Phase II Dose-Finding Study of SK-0403 With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the clinical efficacy and safety of SK-0403 in patients with Type2 Diabetes Mellitus
- Trial name
- NCT00532506
- Testing
- SK-0403
- Where
- 10 sites in Japan
- Sponsor
- Sanwa Kagaku Kenkyusho Co., Ltd.
Type II Diabetes
Association Between Natural Hypoglycemic Foods and Blood Sugar Level: A Pilot Study
Type 2 diabetes patients often do not reach desired control of glycemia despite guidance on changing lifestyle and diet as well as the use of conventional anti-diabetic medication.
- Trial name
- NCT05272839
- Testing
- Hypoglycemic food group, Control group
- Volunteers
- 124 people
- Sponsor
- Antenna Foundation
Antiphospholipid (aPL)-Positive, Rheumatic Arthritis
MENA/Levant Epidemiological, Registry of Immunological & Clinical Traits (MERIT)
The primary objective of this multicenter observational registry is to characterize the clinical, epidemiological, and biological profiles of individuals of Middle Eastern, North African, and Levantine ancestry, including…
- Conditions
- Antiphospholipid (aPL)-Positive, Rheumatic Arthritis, Celiac Disease, Focal Segmental Glomerulosclerosis (FSGS)
- Trial name
- MERIT (NCT07892651)
- Where
- Jordan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Axiom Bioregistry
Type II Diabetes
Impact of the Rapid Normalization of Chronic Hyperglycemia and the Practice of Moderate Physical Activity on the "Receptor Activator of Nuclear Factor-kappa B Ligand / Osteoprotégérine (RANKL / OPG) System in Patients Living With Type II Diabetes
The rapid normalization of hyperglycemia can cause a neuropathy called Diabetes Treatment-Induced Neuropathy (NITD). This phenomenon induces the presence of hyper vascularization and inflammation in contact with the nerve ends.
- Trial name
- RANKL-GLYC (NCT04893135)
- Testing
- pratice physical activity
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Sud Francilien