Clinical trials: Diabetes Mellitus II
Type 1 Diabetes
Atorvastatin in New Onset Type 1 Diabetes Mellitus (T1DM)
The goal of this application is to evaluate the safety and efficacy of atorvastatin as a potential treatment to preserve beta cell function in children and young adults with newly diagnosed type 1 diabetes (T1DM).
- Trial name
- TIDM (NCT00529191)
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Philadelphia
Diabetes Mellitus, Type 2, Dyslipidemia
Acceptability Study of a New Fixed Combination of Fenofibrate 80 mg BID and Metformin 1000 mg BID in Type 2 Diabetes and Dyslipidemia
The present study aims to assess the acceptability of a 4 week treatment of a new fixed-dose combination of fenofibrate and metformin, in patients with type 2 diabetes and dyslipidemia
- Trial name
- NCT00490178
- Testing
- Fenofibrate 80 mg and metformin 1000 mg (fixed combination)
- Where
- 3 sites in France
- Volunteers
- 29 people
- Sponsor
- Solvay Pharmaceuticals
Type 2 Diabetes Mellitus
Muscle Strength Training for Older Adults With Type II Diabetes
This randomised controlled trial aims to investigate a resistance training program for improving glycemic control, muscle mass, strength and functional performance in older patients with Type II Diabetes (T2 DM).
- Trial name
- NCT03280758
- Testing
- Muscle Strengthening exercises
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Non-Insulin-Dependent Diabetes Mellitus, Obesity
Efficacy and Safety of ATL-962 in Obese Diabetics
The purpose of this study is to investigate whether ATL-962 induces weight loss in diabetic patients and whether its safety and tolerability profile is superior to that of orlistat in such patients
- Trial name
- NCT00156897
- Testing
- ATL-962, Orlistat
- Where
- 37 sites in Denmark, Finland and 3 more
- Volunteers
- 600 people
- Sponsor
- Alizyme
Type 2 Diabetes, Insulin Resistance
Blood Flow Responses to an Oral Glucose Tolerance Test in Type 2 Diabetes
The investigators wish to determine whether a short period of exercise training (5-10 days) improves the metabolic and cardiovascular response of people with or at risk of developing type 2 diabetes to eating a meal.
- Trial name
- OGTT (NCT00972452)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Kansas Medical Center
Type II Diabetes Mellitus
A Study Evaluating the Efficacy and the Benefit of Integrated Personalized Diabetes Management (PDM) for Diabetic Patients.
This study is a German, prospective, multicenter, controlled, cluster-randomized, interventional comparative study evaluating the efficacy and benefits of integrated PDM care by measuring HbA1c levels in patients with Type 2…
- Trial name
- PDMProValueDSP (NCT02156349)
- Testing
- Accu-Chek Smart Pix Software, Accu-Chek Smart Pix readout Device
- Where
- 50 sites in Germany
- Volunteers
- 558 people
- Sponsor
- Hoffmann-La Roche
Incretin Hormones Plasma Levels, Gastric Bypass Surgery
A Comparative Study Between Effect Of Mini-gastric Bypass and Single Anastmosis Sleeve Jujenal Bypass On Levels Of GLP-1, GIP, PYY, Insulin Resistance and Type II DM Resolution
The aim of this work is to compare the outcome of Single Anastomosis Sleeve Jejunal Bypass (SASJ) with One Anastomosis Gastric Bypass (OAGB) as regards effect on levels of GLP-1 mainly, PYY and GIP and subsequent effect on…
- Trial name
- NCT07475143
- Testing
- Single anastomosis sleeve jejunal bypass, One anastomosis gastric bypass
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Critical Limb Ischemia (CLI), Diabetic Foot
Intraarterial Infusion of Autologous Bone Marrow in Diabetic Patients With Chronic Ischemia of Lower Limbs (CLI) no Revascularization
The aim of the study is to evaluate the safety and feasibility of autologous bone marrow mononuclear cells autologous administered intra-arterially in the affected limb of diabetic patients with chronic critical ischemia of the…
- Trial name
- NCT00987363
- Testing
- Intraarterial infusion of autologous bone marrow cells
- Where
- 5 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud
Platelet Aggregation, Type 2 Diabetes
Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II
This phase 2 study will include patients suffering from type 2 diabetes mellitus and will first study their response to enteric coated aspirin at a dose of 80 mg per day for a 7-day period.
- Conditions
- Platelet Aggregation, Type 2 Diabetes, Aspirin, Diabetes Mellitus, Type 2
- Trial name
- APPEASEDII (NCT05702463)
- Testing
- Aspirin 81Mg Ec Tab twice daily for 7 days, Aspirin 40Mg Chew Tab twice daily for 7 days, Aspirin 162 mg EC Tab once daily for 7 days
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Montreal Heart Institute
Type 1 Diabetes, Beta Cell Preservation
Long Term Treatment Effect of the Safety, Tolerability and Efficacy of AAT in Type 1 Diabetes
At a previous study the investigators have assessed the safety and efficacy of treatment with AAT(Alpha 1 Antitrypsin)in newly diagnosed type 1 diabetes subjects aiming at beta cells preservation .
- Trial name
- AAT Extension (NCT01661192)
- Testing
- AAT( Alpha 1 Antitrypsin)
- Where
- 2 sites in Israel
- Volunteers
- 12 people
- Sponsor
- Rabin Medical Center
Diabetes Mellitus, Type II
Jordan Diabetes Microclinic Project
The purpose of the study is to provide participants in economically depressed areas of Jordan essential knowledge, practical skills, and intimate support groups-called microclinics-for managing their diabetes.
- Trial name
- NCT01596244
- Testing
- Microclinic
- Where
- 2 sites in Jordan
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Microclinic International
Diabetes Mellitus
Efficacy Study of Pioglitazone Compared to Glimepiride on Coronary Atherosclerotic Disease Progression in Subjects With Type 2 Diabetes Mellitus
The purpose of this study was to determine the efficacy of pioglitazone, once daily (QD), compared to glimepiride on atherosclerotic disease measured by intravascular ultrasound.
- Trial name
- PERISCOPE (NCT00225277)
- Testing
- Pioglitazone, Glimepiride
- Where
- 79 sites in United States, Argentina and 2 more
- Volunteers
- 547 people
- Sponsor
- Takeda
Knee Osteoarthritis, Type II Diabetes
Burger Allen Exercises in Knee OA With Type II Diabetes
There is a potential link between diabetes mellitus (DM) and severity of osteoarthritis .Type 2 diabetes is a part of the metabolic syndrome (Mets) accompanied by ageing and mechanical stress are also a risk factor to…
- Trial name
- NCT05878587
- Testing
- thermotherapy+ TENS+ low intensity high repetition exercises and Buerger Allen, thermotherapy+ TENS+ low intensity high repetition exercises
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Diabetes Mellitus, Type 2, Healthy Males
A First in Human, Single Dose, Safety and Tolerability Study of MKC253 Inhalation Powder in Healthy Adult Males
26 subjects will be enrolled into 5 different dose groups. The trial will consist of a screening, a dosing and a follow-up visit.
- Trial name
- NCT00475371
- Testing
- MKC253 Inhalation Powder
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mannkind Corporation
Chronic Kidney Disease, Type 2 Diabetes
Autologous Neo-Kidney Augment (NKA) in Patients With Type 2 Diabetes and Chronic Kidney Disease (CKD)
A Phase II, Open-Label Safety and Efficacy Study of an Autologous Neo-Kidney Augment (NKA) in Patients With Type 2 Diabetes and Chronic Kidney Disease (RMTX-CL001).
- Trial name
- RMCL-CL001 (NCT02525263)
- Testing
- Neo-Kidney Augment
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Prokidney
Type 2 Diabetes, Blood Pressure
Effects of Potatoes on Blood Pressure in Persons With and Without Type 2 Diabetes Who Follow the DASH Diet for 6 Weeks
This study will be a randomized controlled intervention study that will collect pre-intervention and post-intervention anthropometric health data of men and women aged 18-65 years who have type 2 diabetes and who do not have type…
- Trial name
- NCT05589467
- Testing
- DASH-FP, DASH-NFP, Control
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Texas Tech University
Diabetes Mellitus, Type 2
Pharmacokinetics and Pharmacodynamics of TAK-875 in Subjects With Type 2 Diabetes
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple ascending-doses of TAK-875 in subjects with type 2 diabetes mellitus.
- Trial name
- NCT00949091
- Testing
- TAK-875
- Volunteers
- 60 people
- Sponsor
- Takeda
Type 2 Diabetes
Efficacy and Safety Study of SHR117887 in Combination With Metformin in Patients With Type 2 Diabetes
SHR117887 is a new dipeptidyl peptidase(DPP)-4 inhibitor. This study aims to evaluate the efficacy and safety of SHR117887 in combination therapy with Metformin in patients with Type 2 Diabetes in Metformin monotherapy Who have…
- Trial name
- NCT01984489
- Testing
- SHR117887
- Volunteers
- 120 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Diabetes Mellitus Type 2, Glycemic Control for Diabetes Mellitus
Comparison Between Efficacy of Trelagliptin and Sitagliptin in Type II Diabetic Patients
The goal of this clinical trial is to find out if a medicine called Trelagliptin works as well as another medicine called Sitagliptin to lower blood sugar levels in people with type 2 diabetes who have not reached their target…
- Trial name
- NCT07073768
- Testing
- Trelagliptin 100 mg, Sitagliptin 100mg OD
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Khyber Medical College, Peshawar
Type 2 Diabetes Mellitus
Diabetes Knowledge Assessment
To assess the knowledge of both type 2 diabetics and non-diabetics on diabetes, nutrition, and exercise. Although type 2 diabetics should know more about their disease and its needs, it is not expected they will know…
- Trial name
- NCT00198900
- Testing
- survey of information
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health