Clinical trials: Diabetes Mellitus II
Diabetes Mellitus, Type 1
Evaluation of a Booster Administration of GAD-alum (Diamyd®) in Individuals With Type 1 Diabetes
The objective of the study is to evaluate the feasibility and safety of administering a 4th or 5th intralymphatic booster dose of GAD-alum (Diamyd®) to T1D patients carrying HLA DR3-DQ2, who have earlier been treated with three…
- Trial name
- NCT05351879
- Testing
- GAD-alum (Diamyd) 40 μg/mL
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Linkoeping University
Type II Diabetes
Safety, Pharmacokinetics, and Food Effect of PS1 in Subjects
This is a phase I, double-blind, placebo-controlled, randomized, single- and multiple-ascending dose study to evaluate new study intervention, PS1.
- Trial name
- NCT05176210
- Testing
- PS1
- Where
- Taiwan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Pharmasaga Co. Ltd.
Type II Diabetes Mellitus
Effect of Pioglitazone on Mitochondrial Function in Muscle and Adipose Tissue in Humans
Mitochondrial dysfunction in skeletal muscle results in decreased muscle fatty acid oxidation, leading to conversion of fatty acids into triglycerides and its accumulation inside the muscle tissue.
- Trial name
- PIO (NCT01165190)
- Testing
- pioglitazone
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Arizona State University
Diabetes Mellitus, Type II
Effects of Fatty Acid Delivery on Heart Metabolism and Function in Type 2 Diabetes (T2DM
Type 2 Diabetes Mellitus (T2DM) is a disease that interferes with the body's proper production and use of insulin, a hormone needed to convert sugar into usable energy.
- Trial name
- T2DM (NCT00577590)
- Testing
- Metformin, Rosiglitazone, Lovaza
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Washington University School of Medicine
Type 2 Diabetes
Internet Diabetes Self-Management
Diabetes is a growing health problem causing personal suffering, comorbid conditions, premature death, and high costs to the individual, the health care system and society.
- Trial name
- NCT00372463
- Testing
- 6-week Online Diabetes Self-Management Educational Program
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Robert Wood Johnson Foundation
Diabetes Mellitus, Type 2
A Study of Dulaglutide (LY2189265) in Participants With Type II Diabetes
The main purpose of this study is to evaluate the use of the study drug known as dulaglutide in participants with type II diabetes who are taking once-daily insulin glargine.
- Trial name
- AWARD-9 (NCT02152371)
- Testing
- Dulaglutide, Insulin Glargine, Metformin
- Where
- 40 sites in United States, Czechia and 5 more
- Volunteers
- 300 people
- Sponsor
- Eli Lilly and Company
Diabetic Neuropathies
Biodex Balance System Training in Diabetic Neuropathy
Type II-diabetic neuropathy is the most common and correlated problem with diabetes that deteriorates with the passage of time. Balance disorders are also resulting of movement strategy damage, biomechanical and mechanical…
- Trial name
- NCT04943614
- Testing
- Biodex balance system, conventional exercises
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Riphah International University
Diabetes Mellitus, Hypertension
Effects of Use of a Connected Pillbox On Medication Adherence
Medication adherence is defined as the extent to which a patient takes his or her medication as prescribed by their healthcare provider.
- Conditions
- Diabetes Mellitus, Hypertension, Hyperlipidemia
- Trial name
- (TVHST2DM) (NCT02593032)
- Testing
- Pre-filled trays
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Type 2 Diabetes
The Application of Extremely Low Level Magnetic Fields as Adjunctive Treatment for Type II Diabetes
The purpose of this study is to see if using a device called the Resonator, that puts out very low level electromagnetic fields, effects blood glucose and A1c levels in people with Type 2 Diabetes.
- Trial name
- NCT00982293
- Testing
- Resonator device
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- pico-tesla Magnetic Therapies, LLC
Diabetes Mellitus, Type II
The Supplementary Effects of the Extract of Agaricus Blazei Murril on Type II Diabetes Mellitus (DM)
The purpose of this study is to examine whether the extract of the Agaricus blazei Murill mushroom is effective in the supplementary treatment of type II DM patients.
- Trial name
- NCT00131287
- Testing
- Extract of Agaricus blazei Murill
- Where
- Taiwan
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- ECbiotech Taiwan
Covid19, Diabetes
Camostat and Artemisia Annua vs Placebo in COVID-19 Outpatients
This is a randomized, double-blind, placebo-controlled, multi-arm, multicenter, phase II trial design to allow a rapid efficacy and toxicity assessment of potential therapies (camostat mesilate and artemisia annua) immediately…
- Conditions
- Covid19, Diabetes, Hypertension, Obesity
- Trial name
- NCT04530617
- Testing
- Camostat Mesilate, Artemisia Annua Leaf
- Where
- Mexico
- Volunteers
- 246 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Type 2 Diabetes
Efficacy and Safety Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes
SP2086 is a new dipeptidyl peptidase(DPP)-4 inhibitor. This study aims to evaluate the efficacy and safety of SP2086 in combination therapy with Metformin in patients with Type 2 Diabetes in Metformin monotherapy Who have…
- Trial name
- NCT01969318
- Testing
- SP2086(50 mg q.d.)/Metformin, SP2086 (100 mg q.d.)/Metformin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Type 1 Diabetes
Trial of Intranasal Insulin in Children and Young Adults at Risk of Type 1 Diabetes
In people with type 1 diabetes the beta cells of the pancreas no longer make insulin because the body's immune system has attacked and destroyed the beta cells.
- Trial name
- INITII (NCT00336674)
- Testing
- Intranasal insulin
- Where
- 6 sites in Australia, New Zealand
- Volunteers
- 110 people
- Sponsor
- Melbourne Health
Type 2 Diabetes
Diabetes Scorecard Educational Intervention Study
The purpose of this study is to see if the use of a diabetic scorecard during clinic visits can improve glycemic control, blood pressure control, LDL-cholesterol, aspirin usage, and amount of exercise in adults over age 40 with…
- Trial name
- NCT01339520
- Testing
- Scorecard, Control
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- George Washington University
Cerebral Stroke, Thrombosis, Deep Vein
A Study of Adverse Events and Suspected Adverse Drug Reactions in Patients Under Apixaban for Prevention of Stroke and Systemic Embolism With Non-Valvular Atrial Fibrillation and Venous Thromboembolic Events in Patients Who Have Undergone Elective Hip or Knee Replacement Surgery
To characterize and analyze the number, type and incidence of adverse events/suspected adverse drug reactions in patients treated with Apixaban, according to therapeutic indications approved in Mexico.
- Conditions
- Cerebral Stroke, Thrombosis, Deep Vein, Pulmonary Embolism
- Trial name
- NCT03804125
- Sponsor
- Pfizer
Obesity, Bariatric Surgery
Effects of Caloric Restriction Alone Versus Postoperative Caloric Restriction Following Bariatric Surgery on Glucose Metabolism in Patients With Diabetes Mellitus
Background: Bariatric surgery is the most effective way to achieve significant, long-term weight loss. It has also been shown to be an effective therapy for obese individuals with type 2 diabetes: more than 70 percent of patients…
- Conditions
- Obesity, Bariatric Surgery, Morbid Obesity, Diabetes Mellitus Type 2
- Trial name
- NCT01083108
- Testing
- Roux-en-Y Gastric Bypass, Caloric Restriction
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 1, Autoimmune Diseases
Study to Evaluate the Safety and Feasibility of Diamyd® in Individuals at Risk for Type 1 Diabetes
A 2-arm randomized Phase II Open Label Study to evaluate the safety and feasibility of intralymphatic administration of Diamyd® (Diamyd) also known as retogatein in individuals at risk of Type 1 diabetes carrying the HLA DR3-DQ2…
- Conditions
- Diabetes Mellitus, Type 1, Autoimmune Diseases, Prevention
- Trial name
- NCT05683990
- Testing
- Diamyd
- Where
- Sweden
- Volunteers
- 5 people
- Sponsor
- Diamyd Medical AB
Diabetic Neuropathies, Neuropathic Pain
Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy
This study evaluates the analgesic effect of Omnitram for the treatment of painful diabetic neuropathy. Each subject with diabetic neuropathy will be treated for four weeks with Omnitram and for four weeks with placebo.
- Conditions
- Diabetic Neuropathies, Neuropathic Pain, Pain, Chronic
- Trial name
- NCT03664921
- Testing
- Omnitram Oral Tablet
- Where
- 4 sites in United States
- Volunteers
- 55 people
- Sponsor
- Syntrix Biosystems, Inc.
Dyslipidemia in Patients With Diabetes Mellitus
The HDL Particle Protection Study
Atorvastatin is a statin that significantly decreases LDL level. At 10 mg/day, atorvastatin increases HDL level by 4-5%. At 80 mg/day, atorvastatin does not increase HDL level.
- Trial name
- HDL PROTECT (NCT02125682)
- Testing
- atovastatin 10 mg/day, Atorvastatin 80 mg/day
- Where
- Lebanon
- Volunteers
- 16 people
- Sponsor
- Hotel Dieu de France Hospital
Acute Viral Hepatitis, Diabetes Mellitus
Acute Viral Hepatitis and Diabetes Mellitus
It has been observed that several of patients having prolonged or complicated course of acute viral hepatitis have underlying diabetes.
- Trial name
- NCT00689546
- Where
- India
- Volunteers
- 250 people
- Sponsor
- All India Institute of Medical Sciences