Clinical trials: Diabetes Mellitus II
Diabetes Mellitus, Type II
Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus (T2DM) on Background Therapy With Glimepiride With or Without Metformin
This study will evaluate the safety and efficacy of dutogliptin in patients with type 2 diabetes mellitus (T2DM) who are receiving background therapy of glimepiride with or without metformin.
- Trial name
- NCT00947557
- Testing
- Dutogliptin
- Where
- 147 sites in United States, Belarus and 6 more
- Volunteers
- 677 people
- Sponsor
- Forest Laboratories
Type II Diabetes
Effects of GLP-1 Agonists on CArdiac Steatosis Evaluated by Magnetic Resonance Imaging
Type II diabetes is a known risk factor for heart failure, particularly through the progressive development of diabetic cardiomyopathy.
- Trial name
- LICAS-MR (NCT03498001)
- Testing
- GLP-1 agonists, Cardiac MRI, Follow up by phone
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Overweight or Obesity
Efficacy and Safety of SYH2069 Injection in Obese Participants Without Diabetes.
To evaluate the efficacy and safety of SYH2069 injection compared with placebo in obese Non-diabetic Participants after 28 weeks of treatment.
- Trial name
- NCT07803991
- Testing
- SYH2069 Injection
- Where
- China
- Volunteers
- 360 people
- Sponsor
- CSPC Ouyi Pharmaceutical Co., Ltd.
Glycemic Responses
Blood Glucose Response to Test Foods Containing Brewer's Spent Grain
The objective of this project is to determine the impact of incorporating brewers' spent grain into cookie formulations on postprandial blood glucose absorption levels following consumption.
- Trial name
- BSG-PPG (NCT07446179)
- Testing
- Food Intervention
- Where
- Uruguay
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Católica del Uruguay
Obesity, Diabetes Mellitus, Type II
Impact of Sleep and Meal Timing on Food Intake Regulation
This study will test the hypothesis that a late sleep (Ls) and/or late meal (Lm) behavioral pattern, with equal sleep duration, will promote positive energy balance and insulin resistance (IR).
- Conditions
- Obesity, Diabetes Mellitus, Type II, Cardiovascular Disease
- Trial name
- NCT02347020
- Testing
- Normal Sleep/ Normal Meal, Normal Sleep/ Late Meal, Late Sleep/ Normal Meal
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cardiovascular Disease, Type 2 Diabetes
Effects of Pistachios on Cardiovascular Responses to Stress in Type 2 Diabetes
This study is investigating the effects of three different diets, including a diet with pistachios, on cardiovascular disease risk markers in people with type 2 diabetes.
- Trial name
- Pistachio (NCT00956735)
- Testing
- Pistachio
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Penn State University
Hypertension, Diabete Type 2
Clinical Trial to Evaluate the Efficacy and Safety of Monotherapy Group of HL1113R1 or HL1113R2 Versus HL1113 (Fixed Dose Combination) in Patients With Essential Hypertension and Type II Diabetes Mellitus
This clinical trial is a randomized, active controlled, double blind, parallel, multi center, phase 3 study to evaluate the efficacy and safety of monotherapy group of HL1113R1 or HL1113R2 versus HL1113 (Fixed dose combination)…
- Trial name
- NCT07552389
- Testing
- Test group, Exploratory test group, Control group 1
- Where
- South Korea
- Volunteers
- 228 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Type 2 Diabetes Mellitus, Peripheral Microvascular Symptoms
The Effect of Prostaglandin I2 on the Endothelial Cell Function Disorder in Type 2 Diabetes Mellitus Patients
This study attempts to examine the effect of oral prostaglandin I2 (Beraprost Na), administered for eight weeks, on the endothelial cell functional disorder among asymptomatic high risk diabetes mellitus patients.
- Trial name
- NCT01061060
- Testing
- Prostaglandin I2
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Yonsei University
Gum Disease, Diabetes
Effectiveness of Personalized Oral Hygiene Advice Delivered by Artificial Intelligence or Dental Professionals Versus Standard Oral Hygiene Advice on Oral and Systemic Health in Community-based Type II Diabetes Patients
Diabetes is a systemic condition characterized by elevated blood glucose levels and is associated with multiple long-term complications.
- Trial name
- NCT07841717
- Testing
- AI OHI group, Human-OHI group, Control group
- Volunteers
- 105 people
- Sponsor
- The University of Hong Kong
Type II Diabetes Mellitus
Therapeutic Efficacy of "Abroma Agusta" in HbA1c % in NIDDM
Objective: To ascertain whether homoeopathic medicine ABROMA AUGUSTA has a clinical role in changing the Glycated Hb Level in Diabetes mellitus Type II.
- Trial name
- ABOMNIDDM (NCT02065674)
- Testing
- Abroma Augusta Q (mother tincture)
- Where
- India
- Sponsor
- Fr Muller Homoeopathic Medical College
Diabetes Mellitus Type II
Perioperative Insulin, GIK or GLP-1 Treatment in Diabetes Mellitus
The incidence of diabetes mellitus type II is increasing. More and more patients who need surgery have diabetes mellitus type II.
- Trial name
- PILGRIM (NCT02036372)
- Testing
- Liraglutide, Insulin bolus, GIK infusion
- Where
- 3 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Diabetes Mellitus, Type 2
The Effect of Nitrate on Brown Fat
Type 2 diabetes mellitus (T2DM) is a metabolic condition characterized by chronic hyperglycemia and progressive insulin resistance, which progressively lead to macro- and microvascular damage.
- Trial name
- NCT05342012
- Testing
- Concentrated beetroot juice, Nitrate depleted beetroot juice
- Where
- 4 sites in United Kingdom
- Volunteers
- 13 people
- Sponsor
- Bournemouth University
Diabetes Mellitus
Efficacy of Pioglitazone on Macrovascular Outcome in Patients With Type 2 Diabetes
The purpose of this study is to determine whether pioglitazone, once daily (QD), can delay the time to death, heart attack, acute coronary syndrome, heart bypass surgery, stroke, leg bypass surgery or amputation in patients with…
- Trial name
- PROactive (NCT00174993)
- Testing
- Pioglitazone
- Where
- 19 sites in Austria, Belgium and 17 more
- Volunteers
- 4,373 people
- Sponsor
- Takeda
Type 1 Diabetes
Long-Term Treatment Effect of DiaPep277 in Type 1 Diabetes
The study is an open-label extension study, offering patients who participated and completed previous study 901 to continue treatment with DiaPep277 and clinical follow-up, for 2 additional years.
- Trial name
- NCT00644501
- Testing
- DiaPep277
- Where
- 3 sites in Israel
- Volunteers
- 43 people
- Sponsor
- Andromeda Biotech Ltd.
Diabetes Mellitus, Type 2
Translation, Cultural Adaptation and Validation of the Creole Versions of the EQ-5D and the SF-36 Questionnaires in Patients With Type II Diabetes in Reunion Island, Martinique and Guadeloupe
The evaluation of quality of life in health is particularly important for measuring the impact of the chronic diseases. The scales of measure constitute the main measurement tool in clinical trials because of their psychometrics…
- Trial name
- CreoQol (NCT02898493)
- Where
- France
- Volunteers
- 750 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Cardiovascular Disease, Diabetes Mellitus, Type 2
Effect of Probiotic Supplementation on Endothelial Function II
Researchers at MCW have discovered a new pathway that links the type of bacteria present in the intestines to the severity of heart attacks.
- Trial name
- NCT03267758
- Testing
- Goodbelly first
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Medical College of Wisconsin
Diabetes Mellitus, Type 2
Effect of Whole Body Vibration Training on Glycemic Control in Type II Diabetic Patients
Worldwide, the non-communicable diseases are increasing at an alarming rate in which the cardiovascular diseases and Diabetes Mellitus (DM) are predominantly common in lower middle income countries.
- Trial name
- NCT05083767
- Testing
- Experimental, Control
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Ameen Medical and Dental Center
Hypertension
An Examination of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Patients With Type II Diabetes
This study will examine the ability of olmesartan medoxomil to lower the blood pressure of patients with Type II diabetes and high blood pressure.
- Trial name
- NCT00403481
- Testing
- olmesartan medoxomil, Olmesartan medoxomil plus Hydrochlorothiazide
- Where
- 27 sites in United States
- Volunteers
- 192 people
- Sponsor
- Daiichi Sankyo
Diabetes Mellitus, Liver
Safety Study of Pioglitazone Compared To Glyburide on Liver Function
The purpose of this study is to determine the liver safety of pioglitazone, once daily (QD), versus glyburide taken with metformin and insulin.
- Trial name
- NCT00494312
- Testing
- Pioglitazone, Glyburide
- Volunteers
- 2,120 people
- Sponsor
- Takeda
Hyperbaric Oxygen Therapy, Diabetic Foot Ulcer
Short Duration Hyperbaric Oxygen Therapy to Improve HbA1c, Leukocyte, and Serum Creatinine
The investigators want to evaluate the short duration HBOT can improve glycohemoglobin (HbA1c) levels, leukocyte count, and serum creatinine levels in patients with DFU (diabetic foot ulcer) Wagner 3-4.
- Conditions
- Hyperbaric Oxygen Therapy, Diabetic Foot Ulcer, Type II Diabetes Mellitus
- Trial name
- NCT03615755
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Volunteers
- 30 people
- Sponsor
- Hendry Irawan