Clinical trials: Diabetes Mellitus II
Diabetic Foot, Stem Cell
Stem Cell Derived Exome for Treatment of Diabetic Foot
This trial is designed to investigate the safety and efficacy of patients with diabetic foot by using stem cell derived exome.
- Trial name
- NCT06480123
- Testing
- Skin drug prepared with exome originated from stem cell
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Diabetes Mellitus, Type 2
Pilot Study to Evaluate the Safety and Efficacy of 5-ALA-SFC in Type II Diabetes
The aim of this pilot study is to assess the safety and preliminary efficacy of 5-ALA - SFC at doses up to 200 mg per day in subjects with type II diabetes.
- Trial name
- NCT02481141
- Testing
- 5-ALA-SFC
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- SBI Pharmaceuticals Co, Ltd.
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
mRNA Based-Covid-19 Vaccine Effects on Blood Glucose Levels
To determine if patients with a history of Diabetes Mellitus Type I or II developed a change in blood glucose levels as reported on Continuous glucose monitoring devices (CGMS) within the first week following administration of…
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Hyperglycemia, Vaccine Adverse Reaction
- Trial name
- NCT04923386
- Testing
- None (not interventional)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Levenson, David I., M.D.
Type II Diabetes
Personalized Health Planning in Shared Medical Appointments for Individuals With Type II Diabetes Pilot Study
The primary aim of this study is to examine the feasibility of implementing an evidence based patient engagement strategy, known as personalized health planning (PHP), in the context of a a shared medical appointment (SMA) for…
- Trial name
- NCT02471794
- Testing
- Personalized Health Planning Shared Medical Appointment
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Duke University
Obesity, Physical Activity
Coalition for a Healthier Community-Utah Women and Girls - Phase II (UWAG-II)
This 12-month randomized trial is designed to evaluate the impact of low intensity (quarterly) versus high intensity (monthly) wellness coaching programs on women's success achieving individual health goals related to active…
- Conditions
- Obesity, Physical Activity, Diabetes
- Trial name
- UWAG-II (NCT02470156)
- Testing
- High Intensity Arm (Intervention), Low Intensity Arm (Comparison)
- Where
- United States
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- University of Utah
Diabetes Mellitus Type II, Acute Coronary Syndrome
VERifynow in DIabetes Non-responsiveness: a Study on Switching From Clopidogrel to Prasugrel
The purpose of this study is to determine if, in type 2 diabetic patients undergoing treatment with PCI and a stent, who fail to respond to normal doses of clopidogrel, a loading dose of 60 mg of prasugrel followed by 10 mg once…
- Trial name
- VERDI (NCT01684813)
- Testing
- Prasugrel., Clopidogrel
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Type 2 Diabetes Mellitus
Comparative Interventional Study to Evaluate the Role of LRYGBP, LSG & SMM
A Comparative Interventional Study to Evaluate the Role of Laparoscopic Roux-en-Y Gastric Bypass (LRYGBP), Laparoscopic Sleeve Gastrectomy (LSG) and Standard Medical Management (SMM) in Patients of Type II Diabetes Mellitus (DM)…
- Trial name
- NCT04058730
- Testing
- Laparoscopic Roux en Y Gastric by pass surgery, Laparoscopic Sleeve Surgery, Standard Medical Management
- Where
- 2 sites in India
- Volunteers
- 150 people
- Sponsor
- Max Institute of Minimally Access, Metabolic & Bariatric Surgery
Type II Diabetes Mellitus
Single-centre, Randomised, Double-blind, Placebo-controlled, Four-way Crossover Clinical Study to Investigate Safety and Tolerability and Pharmacokinetics of Single Doses of CM3.1-AC100 in Patients With Type 2 Diabetes
The primary objective of this study is to assess the safety and tolerability of the Glucagon-like peptide-1 (GLP-1) peptide analogue CM3.1-AC100 after single subcutaneous (sc) doses in patients with T2DM.
- Trial name
- NCT01196728
- Testing
- CM3.1-AC100
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- CellMed AG, a subsidiary of BTG plc.
Morbid Obesity, Hyperglycemia
Characteristics of Dendritic Cells Before and After Gastric Banding
A research study to find out more about a specific white blood cell called a dendritic cell. These cells are found in a layer of fat in the body called the omentum.
- Conditions
- Morbid Obesity, Hyperglycemia, Diabetes Mellitus
- Trial name
- NCT00488930
- Testing
- Observational
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of California, San Diego
Type II Diabetes Control
Effect of Ginseng in Type 2 Diabetes
Objective: We aim to evaluate longer term efficacy and safety of AG as an add-on therapy in patients with type 2 diabetes controlled by conventional treatment.
- Trial name
- NCT02923453
- Testing
- CNT 2000 American ginseng extract
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Unity Health Toronto
Head and Neck Squamous Cell Carcinoma
AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic Therapy
Currently, there is a lack of high-quality clinical evidence for subsequent treatment options for recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) after first-line treatment, especially for subsequent treatment…
- Trial name
- NCT06494995
- Testing
- Cadonilimab, Low-dose radiotherapy, SBRT
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Fudan University
Diabetes Mellitus, Type II
Single Dose Escalation Study of PF-05190457 in Healthy Volunteers
PF-05190457 is a novel compound proposed for the treatment of Type 2 diabetes mellitus. The purpose of the study is to evaluate the safety and tolerability of PF-05190457 after administration of a single dose to healthy…
- Trial name
- NCT01247896
- Testing
- PF-05190457
- Where
- Belgium
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Pfizer
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope with Rising Temperatures: an Observational Study, 2nd Wave
The CLIMATE-II Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE-II (NCT06407154)
- Where
- Germany
- Volunteers
- 578 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Diabetes Mellitus
Phase III Study to Evaluate Safety and Efficacy of Added Exenatide Versus Placebo to Titrated Basal Insulin Glargine in Inadequately Controlled Patients With Type II Diabetes Mellitus
Study D5553C00002 is a multicenter, randomized, double-blind, placebo-controlled, parallel group, Phase 3 study to compare the safety and efficacy of exenatide once weekly (EQW) added to titrated basal insulin glargine with or…
- Trial name
- NCT02229383
- Testing
- Exenatide
- Where
- 123 sites in United States, Hungary and 4 more
- Volunteers
- 464 people
- Sponsor
- AstraZeneca
Diabetes Mellitus
Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the efficacy and safety of alogliptin, once daily (QD), combined with metformin in adults with type 2 diabetes mellitus.
- Trial name
- NCT00286442
- Testing
- Alogliptin and metformin, Metformin
- Where
- 56 sites in United States, Argentina and 15 more
- Volunteers
- 527 people
- Sponsor
- Takeda
Type II Diabetes Mellitus
A Study to Evaluate the Effect of Musashino Diabetes Diet in Type II Diabetes Mellitus Disease
Evaluation the change of patients' glycosylated hemoglobin (HbA1c) after 12 weeks diet control
- Trial name
- NCT02446054
- Testing
- Musashino T2DM diet
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Celio Technology Inc.
Overweight and Obesity
Assessment of an Intervention to Prevent Obesity and Diabetes in Latino Farm Workers
This is a study to assess the effectiveness of a culturally appropriate behavioral intervention to reduce obesity levels and ultimately the risk of developing diabetes type II in immigrant Latino farm workers.
- Trial name
- Pasos (NCT01855282)
- Testing
- Behavioral Intervention
- Where
- 2 sites in United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Diabetes Mellitus, Type 2, Obesity
Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population
The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes and the subsequent benefit of improving type II diabetes outcomes in a low socioeconomic Hispanic population.
- Trial name
- NCT05279729
- Testing
- Mobile health application
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Diabetic Foot Ulcer
TWB-103 for Treating Lower Limb Ulcers on Patients With DM
Primary Objective: To assess the safety profile of TWB-103 administered to subjects with diabetic lower limb ulcers Secondary Objective: To explore the efficacy of TWB-103 administered to subjects with diabetic lower limb ulcers
- Trial name
- NCT03624023
- Testing
- TWB-103
- Where
- 2 sites in Taiwan
- Volunteers
- 10 people
- Sponsor
- Transwell Biotech Co., Ltd.
Non-Insulin-dependent Diabetes Mellitus
Study of Metamucil on Blood Glucose and HbA1c in Type II NIDDM Subjects
A double-blind, randomized, placebo-controlled, multi-dose clinical study consisting of 2 phases; 1) an 8-week lead-in period during which patients followed a diet judged to be within the acceptable guidelines of the ADA, and 2)…
- Trial name
- NCT01582282
- Testing
- 3.4 g psyllium BID, 6.8g psyllium BID
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Procter and Gamble