Clinical trials: Diabetes Mellitus II
Diabetes Type II
Clinical Study to Compare Various Dosing and Titration Guidelines of Insulin Delivered Via V-Go ® in Patients With Type 2 Diabetes Initiating Basal Bolus Therapy in Primary Care Offices
The aim of the study is to observe patients with Type 2 Diabetes on basal insulin alone or basal insulin with oral agents can be efficiently and safely started with meal time insulin using U100 rapid acting insulin analog and…
- Trial name
- TITRATE (NCT02361489)
- Testing
- V-Go
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Valeritas, Inc.
Diabetes
A Randomized Trial of Electronic Integration of Care for Better Diabetes Outcomes; The COMPETE II Study
This study will evaluate whether the use of an electronic diabetes tracker by both patients and family physicians in Ontario improves diabetes outcomes, satisfaction with care and with technology and health data privacy issues.
- Trial name
- COMPETEII (NCT00813085)
- Testing
- Electronic disease management decision support
- Where
- Canada
- Volunteers
- 511 people
- Sponsor
- McMaster University
Type 2 Diabetes Mellitus
Effect of 13-Week Treatment With Vildagliptin as Add-On Therapy to Improve Glucose Variability in Type II Diabetes
The purpose of the study is to assess if the addition of vildagliptin as add-on therapy improves glucose variability in type 2 diabetes mellitus (T2DM) patients inadequately controlled with insulin, with special emphasis in…
- Trial name
- VIDA (NCT01862263)
- Testing
- Vildagliptin, Insulin
- Where
- 13 sites in Mexico
- Volunteers
- 191 people
- Sponsor
- Novartis Pharmaceuticals
Diabetes Mellitus, Type II
Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study Of PF-06291874 As Oral Monotherapy To Treat Adults With Type 2 Diabetes Mellitus
This study is going to assess the safety and tolerability of PF-06291874 in adults with Type 2 Diabetes Mellitus as monotherapy, to evaluate the significance of overall glycemic control in these subjects.
- Trial name
- NCT02175121
- Testing
- PF-06291874
- Where
- 19 sites in United States
- Volunteers
- 172 people
- Sponsor
- Pfizer
Hypertension
Study to Evaluate the Effect of Micardis® / MicardisPlus® on Metabolic Parameters in Patients With Essential Hypertension and Diabetes Mellitus
The primary objective is to evaluate the effect of the treatment with Micardis® or MicardisPlus® on blood pressure. Secondary objectives are the effect of Micardis® / MicardisPlus® on metabolic parameters (triglycerides…
- Trial name
- NCT02242825
- Testing
- Micardis®, MicardisPlus®
- Volunteers
- 8,148 people
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Type 2
Safety and Tolerability of Pioglitazone-Azilsartan in Subjects With Type 2 Diabetes
The purpose of this study is to determine the safety and tolerability of pioglitazone-azilsartan, once daily (QD), in patients with type 2 diabetes mellitus.
- Trial name
- NCT01124656
- Testing
- Pioglitazone-Azilsartan
- Volunteers
- 26 people
- Sponsor
- Takeda
Combined Hepatocellular-cholangiocarcinoma, Liver Neoplasms
Phase II Clinical Study on the Efficacy and Safety of the Combination of Cadonilimab and Capecitabine in Adjuvant Therapy for Combined Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma
Title: A Study of Cadonilimab Combined with Capecitabine After Surgery for Mixed Type Liver Cancer This is a phase II clinical trial.
- Trial name
- NCT07243951
- Testing
- Cadonilimab, Capecitabine
- Volunteers
- 75 people
- Sponsor
- Shanghai Zhongshan Hospital
Type I Diabetes
A Phase II Trial to Examine the Effect of Subcutaneous Exenatide (Bydureon®) on Glucose Control in Patients With Type I Diabetes
The goal of the proposed pilot study is to determine whether glucose control can be improved with Bydureon treatment in patients with type I diabetes (T1D)
- Trial name
- NCT01928329
- Testing
- Exenatide (Bydureon®)
- Where
- 8 sites in United States
- Volunteers
- 79 people
- Sponsor
- Yale University
Gestational Diabetes Mellitus
Mobile Health App to Reduce Diabetes in Latina Women With Prior Gestational Diabetes II
The investigators will conduct a pre-post study to evaluate the effectiveness of the Hola Bebe intervention on improving self-efficacy for healthy eating and physical activity, and on weight loss among Hispanic women with recent…
- Trial name
- NCT05489172
- Testing
- Hola Bebe
- Where
- 3 sites in United States
- Volunteers
- 77 people
- Sponsor
- Environment and Health Group, Inc.
Dyslipidemia Associated With Type II Diabetes Mellitus
Moderate-intensity Statin vs. Individualized LDL-C Target-based Therapy in Older Adults With Type 2 Diabetes (iTARGET-Elderly Study)
Statins are the cornerstone of cardiovascular disease (CVD) prevention through the lowering of low-density lipoprotein cholesterol (LDL-C).
- Trial name
- NCT07359105
- Testing
- Moderate-intensity statin monotherapy, Ezetimibe or ezetimibe-statin combination therapy
- Where
- 2 sites in South Korea
- Volunteers
- 2,186 people
- Sponsor
- Sin Gon Kim
Diabetic Foot Ulcer
Clinical Study of ALLO-ASC-SHEET in Subjects With Diabetic Wagner Grade II Foot Ulcers
This is a phase 2 double-blind clinical study to evaluate the efficacy and Safety of ALLO-ASC-SHEET in subjects with Diabetic Wagner Grade II Foot Ulcers, compared to placebo therapy.
- Trial name
- NCT04497805
- Testing
- ALLO-ASC-SHEET
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Anterogen Co., Ltd.
Diabetes Mellitus, Type II, Overweight or Obesity
Differences in Postprandial Glucose Changes
Following a meal, in nondiabetic individuals, blood glucose rises to peak at 1hr and returns to baseline in 2 - 3 hours. In T2DM, this peak is higher and prolonged.
- Trial name
- NCT05957224
- Testing
- Shake 1 then Shake 2, Shake 2 then Shake 1
- Volunteers
- 25 people
- Sponsor
- The University of The West Indies
Type 2 Diabetes Mellitus (T2DM), Endothelial Dysfunction
Diabetes & Vardenafil
Given the protective effect of nitric oxide (NO) on the endothelium and the results obtained so far in short-term, continuous treatment with phosphodiesterase-5 (PDE5) inhibitors on parameters of endothelial function, we…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Endothelial Dysfunction, Erectile Dysfunction
- Trial name
- DiVa (NCT02219646)
- Testing
- Vardenafil
- Where
- Italy
- Volunteers
- 54 people
- Sponsor
- Azienda USL Modena
Hypertension, Diabetes Mellitus, Type 2
DETAIL Study: Diabetes Exposed to Telmisartan and Enalapril
To compare the renal consequences of two different approaches to blocking the renin angiotensin system in subjects with hypertension and concurrent Type II diabetes mellitus and diabetic nephropathy.
- Trial name
- NCT00274118
- Testing
- telmisartan, enalapril
- Where
- 37 sites in Denmark, Finland and 4 more
- Volunteers
- 250 people
- Sponsor
- Boehringer Ingelheim
Insulin Resistance
Nutritional Intervention of Type II Diabetes Mellitus by Vitamin D in Qatar
There is an association between elevated Type II Diabetes Mellitus (T2DM) risk and low serum levels of vitamin D. It is important to examine whether Vitamin D can enhance oral glucose tolerance in individuals at risk for…
- Trial name
- NCT02098980
- Testing
- Vitamin D
- Where
- Qatar
- Volunteers
- 200 people
- Sponsor
- Supreme Council Of Health, Qatar
Gestational Diabetes, Hypertensive Disorder of Pregnancy
Mobile-based Obstetric Monitoring for Pregnancies Complicated by Hypertension and/or Diabetes (MOM-HD)
Hypertensive disorders during pregnancy (HDP) and gestational diabetes (GDM) are among the leading complications in pregnancy, significantly contributing to global maternal and fetal morbidity and mortality.
- Trial name
- MOM-HD (NCT07243886)
- Testing
- MOM-HD, Standard Care
- Where
- 3 sites in Nepal
- Volunteers
- 864 people
- Sponsor
- Rutgers, The State University of New Jersey
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type II
Effect of Liraglutide (Victoza) on Inflammation in Human Adipose Tissue and Blood
The objective of this study is to test the hypothesis that liraglutide (commonly known as Victoza) can promote an anti-inflammatory macrophage phenotype in human adipose tissue and blood, thereby reducing localized and systemic…
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Type II, Diabetes Mellitus, Adult-Onset, Inflammation
- Trial name
- NCT02650206
- Testing
- Victoza (liraglutide) with dietician monitoring
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Stanford University
Renal Disorder Associated With Type II Diabetes Mellitus
May Metformin be Used in Renal Failure?
The study is to treat metformin dose-escalation diabetic subjects of all stages of renal failure (stages 1-5) and compare their rates of erythrocyte metformin (best reflections of a possible accumulation than those of plasma) to…
- Trial name
- NCT02710448
- Testing
- Metformin
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hypertension
Retrospective Survey for Patients With Hypertension and Diabetes Mellitus
This study will address the treatment rate and control rate of hypertension, treatment pattern and factors to affect blood pressure control by examining (retrospective) medical records of hypertension patients having Type 2…
- Trial name
- CRYSTAL (NCT00681278)
- Where
- 13 sites in South Korea
- Volunteers
- 2,000 people
- Sponsor
- AstraZeneca
Type 2 Diabetes
A Study of the Effectiveness and Safety of SP2086 to Treat Type 2 Diabetes
SP2086 is a new dipeptidy1 peptidase(DPP)-4 inhibitors. This study aims to explore the effective dose range of SP2086 in Patients with type 2 diabetes.
- Trial name
- NCT01969357
- Testing
- 50 mg SP2086, 100 mg SP2086, 200 mg SP2086
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.