Clinical trials: Diabetes Mellitus II
Type II Diabetes Mellitus, Efficacy, Self
Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in T2DM Patients - EASE Study
Study Objective To evaluate the safety and tolerability of Empagliflozin with or without metformin in patients with Type II Diabetes Mellitus in the Pakistani population.
- Conditions
- Type II Diabetes Mellitus, Efficacy, Self, Safety Issues
- Trial name
- EASE (NCT05164263)
- Testing
- Empagliflozin
- Where
- 6 sites in Afghanistan, Kenya and 3 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Getz Pharma
Dyslipidemia Associated With Type II Diabetes Mellitus
Efficacy and Safety of the Fixed-dose Combination Atorvastatin/Fenofibrate vs Atorvastatin in Patients With T2D and DLP.
Phase IIIb, randomized, longitudinal, prospective, multicenter study to evaluate the efficacy and safety of the fixed-dose combination atorvastatin / fenofibrate versus atorvastatin on the lipid profile of patients with type 2…
- Trial name
- NCT04882293
- Testing
- Atorvastatin 20 mg / Fenofibrate 160 mg in fixed dose, Atorvastatin (Lipitor ®)
- Where
- Mexico
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Diabetes Mellitus, Type 2
A Study in Type 2 Diabetic Subjects on Stable Metformin Therapy to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Co-administering Single and Multiple Oral Doses of GSK1292263
A study in type 2 diabetic subjects on stable metformin therapy to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of co-administering single and multiple oral doses of GSK1292263
- Trial name
- NCT01128621
- Testing
- GSK1292263, Sitagliptin
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type 2
A Phase II Study to Evaluate the Effects of Oral ONO-5129 in Type 2 Diabetes Mellitus
The objectives of this study are to characterize the pharmacodynamic profile, safety and tolerability of ONO-5129 in patients with Type 2 Diabetes mellitus
- Trial name
- NCT00212641
- Testing
- ONO-5129
- Where
- 67 sites in United States
- Volunteers
- 105 people
- Sponsor
- Ono Pharma USA Inc
Diabetic Foot Ulcers
Safety and Efficacy of Gentamicin Topical Gel (AppliGel-G) for Treatment of Mild to Moderately Infected Diabetic Foot Ulcers
The purpose of this study is to determine whether AppliGel-G (Gentamicin topical gel) plus oral Ciprofloxacin / Doxycycline are safe and effective in the treatment of mild to moderately infected foot ulcers in diabetic patients.
- Trial name
- NCT02036528
- Testing
- Gentamicin Topical Gel, Ciprofloxacin, Doxycycline
- Where
- 7 sites in United States
- Volunteers
- 9 people
- Sponsor
- Royer Biomedical, Inc.
Type II Diabetes Mellitus
Prospective Randomized Trials of Gastric Bypass Surgery in Patients With Type II Diabetes Mellitus
Although intensive medical treatment of diabetes has clearly been demonstrated to be worthwhile, it has not been a total success in diabetes treatment for a variety of reasons including lack of response to medication.
- Trial name
- T2DM (NCT00540462)
- Testing
- gastric bypass, sleeve gastrectomy
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Min-Sheng General Hospital
Type 2 Diabetes Mellitus
A Study of TG103 Injection in Overweight/Obese Subjects With Type 2 Diabetes
The main purpose of this study is to evaluate the efficacy, safety, PK and PD characteristics of different doses of TG103 injection in overweight/obese subjects with type 2 diabetes mellitus.
- Trial name
- NCT05063253
- Testing
- TG103
- Volunteers
- 208 people
- Sponsor
- CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.
Diabetes Mellitus, Type 2
An Evaluation of Glycemic Control Effects of Mono Therapy CKD-501 in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate and confirm hypoglycemic efficacy and safety of CKD-501 as mono therapy in patients with type 2 diabetes treated once daily for 24 weeks in comparison to placebo.
- Trial name
- NCT01001611
- Testing
- CKD-501 0.5mg
- Where
- 9 sites in South Korea
- Volunteers
- 173 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Intradermal Injections
A Pilot Study to Assess the Safety, PK and PD of Insulin Injected Via MicronJet or Conventional Needle
The purpose of this study is to compare glucose pharmacokinetics and insulin pharmacodynamics injected via the MicronJet in comparison with a conventional needle.
- Trial name
- MicronJet (NCT00602914)
- Testing
- MicronJet
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- NanoPass Technologies Ltd
Diabetes Mellitus, Cardiac Event
Intraoperative Insulin Administration at Cardiac Surgery for Diabetic Patients
The primary objective of the study was to explore which insulin-based regimen is better, infusion or bolus regimen, for intraoperative management of glucose level for the diabetic patient at cardiac surgery.
- Trial name
- NCT04824586
- Testing
- Fast-acting human insulin
- Where
- Jordan
- Volunteers
- 70 people
- Sponsor
- The Hashemite University
Diabetes Type 2
Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus
Randomized, double-blind, placebo-controlled, parallel group study.
- Trial name
- NCT02496000
- Testing
- ORMD-0801
- Where
- 34 sites in United States
- Volunteers
- 188 people
- Sponsor
- Oramed, Ltd.
Diabetes Mellitus, Type 1
Safety and Efficacy of PEG-Encapsulated Islet Allografts Implanted in Type I Diabetic Recipients
Insulin dependent Type I diabetics require daily insulin therapy to normalize blood glucose but may have difficulty with significant glycemic excursions and hypoglycemic episodes and crises.
- Trial name
- NCT00260234
- Testing
- Allogeneic Cultured Islet Cells (human); Encapsulated
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Novocell
Type 2 Diabetes
Montbretin Clinical Trial in Healthy Volunteers and Type 2 Diabetics
The goal of this clinical trial is to test the investigational product, Montbretin A (MbA) in either individuals with type 2 diabetes (T2D) or healthy participants.
- Trial name
- MbA (NCT05826054)
- Testing
- Montbretin A
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Robert Petrella
Diabetes Mellitus
Pioglitazone Study of Triglyceride Changes in Subjects With Type 2 Diabetes After Conversion From Rosiglitazone.
The purpose of this study is to measure the triglyceride changes in subjects with type 2 diabetes mellitus taking pioglitazone, once daily (QD), following treatment conversion from rosiglitazone.
- Trial name
- COMPLEMENT (NCT00672919)
- Testing
- Pioglitazone
- Where
- 53 sites in United States, Puerto Rico
- Volunteers
- 305 people
- Sponsor
- Takeda
Hypertension
Effect Of Carvedilol Versus Metoprolol On Glycemic Control In Patients With Type II Diabetes And Hypertension
Evaluation of the effect of two different antihypertensive treatments on control of glucose in Type II diabetic patients with high blood pressure
- Trial name
- NCT00060931
- Testing
- carvedilol, metoprolol
- Where
- 119 sites in United States
- Volunteers
- 501 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type II, Hypoglycemia
Effects of Mild Hypoglycaemia on Cognitive Function in Type 2 Diabetes
Hypoglycaemia in subjects suffering from type 2 diabetes may have substantial consequences including a significant negative impact on quality of life.
- Conditions
- Diabetes Mellitus, Type II, Hypoglycemia, Cognitive Change
- Trial name
- NCT03014011
- Testing
- Hypoglycaemic clamp, Euglycaemic clamp
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- Bispebjerg Hospital
Type 2 Diabetes
SGLT2i, Hepatic Glucose Production, and SNS
In this study, PI will test the hypothesis that distinct mechanisms account for the SGLT2i-induced stimulation of ketogenesis and lipolysis versus endogenous (hepatic) glucose production in patients with type 2 diabetes (T2D)…
- Trial name
- NCT07053293
- Testing
- Empagliflozin 25 MG
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Diabetes Mellitus
Long-term Safety of Alogliptin in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the long-term safety of alogliptin, once daily (QD), following participation in 1 of 7 controlled studies in patients with type 2 diabetes mellitus.
- Trial name
- NCT00306384
- Testing
- Alogliptin
- Where
- 114 sites in United States, Argentina and 10 more
- Volunteers
- 3,323 people
- Sponsor
- Takeda
Type II Diabetes Mellitus
Effects of Eccentric Training on Glycemic Control and Quality of Life in Patients With Type II Diabetes Mellitus
Diabetes is defined by the level of hyperglycemia its a metabolic chronic disorder that furthur lead to life threatning medical conditions however, the prevalence of diabetes is rapidly increasing day by day in both developed and…
- Trial name
- NCT06387550
- Testing
- Eccentric Training
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Foundation University Islamabad
Myocardial Injury
Propofol Cardioprotection for Type II Diabetics
The purpose of this study is to determine if an intravenous anesthetic with antioxidant properties will protect the heart of diabetic patients from injury while undergoing coronary bypass surgery.
- Trial name
- NCT00734383
- Testing
- Propofol
- Where
- Canada
- Volunteers
- 137 people
- Sponsor
- University of British Columbia