Clinical trials: Diabetes Mellitus II
Diabetes Mellitus Type 2
Safety and Efficacy Study of EGT0001442 in Subjects With Type 2 Diabetes Mellitus
The purpose of this study was to assess the effect of EGT0001442 on fasting plasma glucose after 28 days of treatment in subjects with type 2 diabetes.
- Trial name
- NCT01029704
- Testing
- EGT0001442
- Where
- 12 sites in United States, Canada
- Volunteers
- 151 people
- Sponsor
- Theracos
Age Related Macular Degeneration, Diabetic Retinopathy
Strategies for Improving Linkage-to-Care After Eye Disease Screening
The goal of this randomized, parallel-group, controlled trial is to compare methods of improving linkage-to-care for participants in the Village Integrated Eye Worker II (VIEW II) trial who are referred to the eye hospital…
- Conditions
- Age Related Macular Degeneration, Diabetic Retinopathy, Glaucoma
- Trial name
- NCT06943599
- Testing
- Text Message Reminder, Health Worker Visit
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- University of California, San Francisco
Diabetes Mellitus, Type 2
Allogeneic Mesenchymal Human Stem Cells Infusion Therapy for Endothelial DySfunctiOn in Diabetic Subjects
This is a 16 subject trial to demonstrate the safety of allogeneic hMSCs administered via infusion therapy for diabetic subjects with endothelial dysfunction.
- Trial name
- ACESO (NCT02886884)
- Testing
- 20 million Allogeneic Mesenchymal Human Stem Cells, 100 million Allogeneic Mesenchymal Human Stem Cells
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Joshua M Hare
Type2 Diabetes
Pilot of Virtual Health Coaching Utilizing Lifestyle for Under-Resourced Patients With Type II Diabetes
Accessible and effective interventions for chronic diseases such as diabetes are especially needed in the under-resourced patient population.
- Trial name
- NCT04872647
- Testing
- Phone-Based Health Coaching Utilizing Lifestyle Action Plans
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Beacon Health System
Diabetes, Critical Limb Ischemia
Feasibility of Peripheral Angioplasty in Type D TASCII Lesions
This observational prospective study will evaluate, according o usual local clinical practice, feasibility of endoluminal revascularization in diabetic patients with type C and D lesions, according to TASC II Criteria.
- Trial name
- NCT01297387
- Testing
- PTA BPG procedure,
- Where
- Italy
- Volunteers
- 344 people
- Sponsor
- IRCCS Multimedica
Diabetes Mellitus, Type 2
Investigation for Clinical Efficacy and Safety of Ipragliflozin 50mg and 100mg on Type II Diabetes
The purpose of this study is to evaluate clinical efficacy and safety of Sodium Glucose Co-transporter 2 (SGLT2) inhibitor, ipragliflozin, at doses of 50mg and 100mg, for Type II Diabetes under usual care.
- Trial name
- HARUKAS (NCT02317484)
- Testing
- Ipragliflozin (SGLT2 inhibitor)
- Where
- Japan
- Volunteers
- 231 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Obesity, Type 2 Diabetes Mellitus
Efficacy of 2 Diet Plans Designed for People With Type II Diabetes on Weight and Health Measures
The objective of this study is to evaluate the efficacy of Medifast Plus for Diabetics compared to a standard weight loss treatment program, in terms of changes in weight loss in overweight men and women over an 86 week active…
- Trial name
- NCT00198757
- Testing
- Medifast Plus for Diabetics Meal Replacement Supplements, Standard ADA recommended diet for type 2 diabetics
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Type2 Diabetes
Efficacy of Multigrain Supplementation in Type II Diabetes Mellitus
The objective of this study is to evaluate the efficacy of instant multigrain supplementation on the glycemic status, cardiometabolic implications, oxidative stress and nutritional status in Type II DM patients.
- Trial name
- NCT04597229
- Testing
- Instant multigrain supplement
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- Universiti Sains Malaysia
Diabetes Mellitus, Type 2
Plant-based Ingredient on Post Prandial Glucose in Type II Diabetes
Effects of a plant based ingredient on blood glucose in Type II diabetes patients.
- Trial name
- NCT02256332
- Testing
- Low dose plant based ingredient, High dose plant based ingredient, Reference food format
- Where
- 2 sites in India
- Volunteers
- 24 people
- Sponsor
- Unilever R&D
Renal Insufficiency, Chronic, Diabetes Mellitus, Type 2
Phase II Pharmacodynamic Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease
This study assesses the effects of a new formulation of bardoxolone methyl on eGFR in Patients with Chronic Kidney Disease and Type 2 Diabetes.
- Trial name
- NCT01053936
- Testing
- Bardoxolone methyl (amorphous dispersion)
- Where
- 26 sites in United States
- Volunteers
- 129 people
- Sponsor
- Biogen
Diabetes Mellitus, Type 2
Study Of AVANDAMET® With Or Without Insulin In Type II Diabetes Mellitus Patients. AVANDAMET® is a Registered Trademark of the GSK Group of Companies.
This study was designed to test the safety and efficacy (how well it works) of AVANDAMET in combination with insulin in improving the control of blood sugar when compared with taking insulin on its own.
- Trial name
- NCT00069836
- Testing
- Rosiglitazone/metformin
- Where
- 93 sites in Austria, France and 3 more
- Volunteers
- 272 people
- Sponsor
- GlaxoSmithKline
Type 1 Diabetes Mellitus
Safety and Efficacy of Overnight Closed Loop in Children With Type 1Diabetes Mellitus in Luxembourg
The purpose of this study is to validate current algorithms and evaluate safety and efficacy of overnight closed loop insulin delivery (FlorenceD2 system) in children with type 1 diabetes between 6 - 12 years of age in Luxembourg…
- Trial name
- NCT02099409
- Testing
- FLORENCED2
- Where
- 2 sites in Luxembourg
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier du Luxembourg
Obesity, Hypertension
BALANCE Diet Implementation in Primary Health Care: a Cluster Randomized Type II Hybrid Implementation Study
This is an implementation type II hybrid study with randomisation in cluster, whose objective is to compare two strategies of implementation of the Brazilian cardioprotective diet guidelines in primary health care in two…
- Conditions
- Obesity, Hypertension, Diabetes, Dyslipidemias
- Trial name
- Implementa-MAC (NCT05310526)
- Testing
- Training Group
- Where
- Brazil
- Volunteers
- 786 people
- Sponsor
- Hospital do Coracao
Obesity, Insulin Resistance
Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents With Obesity
Background: About 40 percent of adults and 20 percent of adolescents in the U.S. have a body mass index over 30 kg/m2. Being overweight may lead to a state of low-level inflammation. This may cause health problems.
- Conditions
- Obesity, Insulin Resistance, Inflammation
- Trial name
- NCT05017571
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Gastroparesis, Gastroparesis Nondiabetic
Gastroparesis Registry 4
The Gastroparesis Registry 4 (GpR4) is an observational study of patients with symptoms of gastroparesis (Gp) and functional dyspepsia (FD) with either delayed or normal gastric emptying.
- Conditions
- Gastroparesis, Gastroparesis Nondiabetic, Gastroparesis Due to Diabetes Mellitus Type I, Gastroparesis Due to Diabetes Mellitus Type II
- Trial name
- GpR4 (NCT05846802)
- Where
- 6 sites in United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Nutritional and Metabolic Diseases, Metabolic Syndrome
Effect of Moringa Oleifera Dehydrated Leaf Powder on the Components of Metabolic Syndrome in Mexican Adults.
Background: The increase in chronic degenerative diseases caused by Metabolic Syndrome (MS) has prompted the search for natural alternatives to develop new medications and to know the mechanism and dosages for their proper use.
- Trial name
- MOMS (NCT07194577)
- Testing
- Moringa oleifera
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Universidad de Colima
Male Subjects With Type II Diabetes (T2DM)
Assessment of the Safety, Tolerability and Pharmacodynamics After Administration of One Dose of AZD8601 to Male Patients With Type II Diabetes Mellitus (T2DM)
This study will be a phase I, first time in human (FiH), randomized, single-blind, placebo-controlled, SAD study in male patients with T2DM, performed at a single study center.
- Trial name
- NCT02935712
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- AstraZeneca
Type I Diabetes Mellitus With Ulcer, Type II Diabetes Mellitus With Ulcer
Safety Study of Stem Cells Treatment in Diabetic Foot Ulcers
Diabetes Mellitus (DM) can be regarded as one of the "epidemics" of the western world. DM contributes to severe morbidity and mortality due to damage in the target organs (neuropathy, vasculopathy, nephropathy, retinopathy).
- Trial name
- NCT01686139
- Testing
- ABMD-MSC
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Sheba Medical Center
Type 1 Diabetes
Efficacy and Safety of Diamyd® in Children and Adolescents With Type 1 Diabetes
This is a randomized, placebo-controlled phase II study to investigate if a prime and boost of 20ug Diamyd® (rhGAD65 formulated in Alhydrogel®), administered subcutaneously four weeks apart, is safe and can preserve beta cell…
- Trial name
- NCT00435981
- Testing
- rhGAD65 formulated in Alhydrogel® (Diamyd®)
- Where
- 8 sites in Sweden
- Volunteers
- 70 people
- Sponsor
- Diamyd Therapeutics AB
Esophageal Squamous Cell Carcinoma, Surgery
PPIO-007 Correlation Analysis of Type II Diabetes Mellitus on Short-term and Long-term Outcomes of Patients With Esophageal Squamous Cell Cancer Undergoing Minimally Invasive Esophagectomy
To date, there is controversy as to whether type II diabetes mellitus is associated with adverse short- and long-term outcomes in patients with esophageal squamous cell carcinoma undergoing minimally invasive esophagectomy.
- Trial name
- NCT06333665
- Testing
- Whether there is type 2 diabetes mellitus before surgery
- Where
- China
- Volunteers
- 605 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University