Clinical trials: Diabetes Mellitus II
Dyslipidemias, Diabetes Mellitus, Type 2
GWMD1092 - GWP42003 : GWP42004 Together Plus Alone in Type II Diabetes
This 15-19 week study is being conducted by GW Pharma Ltd as a pilot study in order to determine the efficacy and safety of two cannabinoids: GWP42004 and GWP42003 alone, or in combination in patients with Type 2 diabetes.
- Trial name
- NCT01217112
- Testing
- GWP42003, GWP42004
- Where
- 5 sites in United Kingdom
- Volunteers
- 62 people
- Sponsor
- Jazz Pharmaceuticals
Type 2 Diabetes Mellitus
Effect of L-Citrulline Supplementation on Arginase Activity and Vascular Function in Diabetes
Arginase has recently been implicated in an array of vascular conditions including atherosclerosis , hypertension and vascular complication of diabetes.
- Trial name
- NCT03358264
- Testing
- L-citrulline
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Type II Diabetes Mellitus
Efficacy and Safety Study of JTT-654 in Type 2 Diabetic Patients
The purpose of this study is to evaluate the effect of JTT-654 on diabetes as well as the safety, tolerability and pharmacokinetics of JTT-654 in type 2 diabetic patients.
- Trial name
- NCT00997152
- Testing
- JTT-654
- Where
- 42 sites in United States
- Volunteers
- 152 people
- Sponsor
- Shionogi Inc.
Metabolic Disorders, Non-alcoholic Steatohepatitis
A Study to Understand the Safety, Tolerability, and Activity of Drug in Body Over a Period of Time of AZD2693, in Subjects of Non-Childbearing Potential in Overweight But Otherwise Healthy Subjects, and Healthy Chinese and Japanese Subjects
This Phase 1, first-in-human (FiH), single-ascending-dose (SAD) study, will assess the safety and tolerability and characterize the pharmacokinetics (PK) of AZD2693, following subcutaneous (SC) SAD administration of AZD2693 in…
- Trial name
- NCT04142424
- Testing
- AZD2693
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Obesity, Type 2 Diabetes
Low Carbohydrate Diet Compared to Calorie and Fat Restricted Diet in Patients With Obesity and Type II Diabetes
This study is designed to address the hypothesis that in obese patients with type 2 diabetes mellitus (DM), a low carbohydrate diet not specifically restricted in calories compared to low fat, caloric restricted diet over 24…
- Conditions
- Obesity, Type 2 Diabetes, Hyperlipidemia
- Trial name
- NCT00108459
- Testing
- Low Carbohydrate Diet
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- US Department of Veterans Affairs
Diabetes Mellitus, Type II
Study of Effectiveness of Liraglutide Added to High Dose Insulin in Type II Diabetics
The purpose of this study is to determine the effect of adding liraglutide to high dose insulin therapy compared to high dose insulin therapy alone in patients with insulin-treated Type 2 diabetes with insulin requirements of >…
- Trial name
- NCT01654120
- Testing
- Liraglutide, Insulin
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Mountain Diabetes and Endocrine Center
Type 2 Diabetes Mellitus (T2DM)
UBT251 Injection Phase II (Type 2 Diabetes Mellitus) Study
The purpose of this study is to evaluate the efficacy of UBT251 injection after 24 weeks of continuous administration in patients with type 2 diabetes mellitus and to recommend the dosing regimen for the Phase III clinical trial.
- Trial name
- T2DM (NCT07163624)
- Testing
- Semaglutide Injection (Ozempic®)
- Where
- China
- Volunteers
- 211 people
- Sponsor
- The United Bio-Technology (Hengqin) Co., Ltd.
Diabetes
Physical Activity Advice in Diabetics at Annual Review
Type II diabetes is an important condition with a UK prevalence of 3.54% affecting approximately 2.5 million people across the country.
- Trial name
- PAADAR (NCT01351181)
- Testing
- Leaflet, Exercise Advice, Normal Care
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Ship Street Surgery
Diabetic Nephropathy
Safety, Tolerability and Pharmacokinetic Study of MT-3995 at a Low Dose in Subjects With Diabetic Nephropathy
The purpose of this study is to evaluate safety, tolerability and pharmacokinetics of MT-3995 in Subjects with Diabetic Nephropathy.
- Trial name
- NCT02205372
- Testing
- MT-3995
- Where
- Japan
- Volunteers
- 31 people
- Sponsor
- Tanabe Pharma Corporation
Diabetes Mellitus, Type II, Type 2 Diabetes
TARDIS - Photo Elicitation and Intervention
Veterans with type 2 diabetes (T2D) may become overwhelmed with the self-management behaviors needed to maintain optimal health.
- Conditions
- Diabetes Mellitus, Type II, Type 2 Diabetes, Diabetes Distress, Self Management
- Trial name
- TARDIS (NCT06972251)
- Testing
- TARDIS Photo Elicitation, TARDIS Intervention
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- VA Office of Research and Development
Type II Diabetes
Evaluation of Effects of Dibifree® on Regulation of Blood Sugar and HbA1c in Patients With Type II Diabetes
At present, diabetic patients mainly use drugs to control blood sugar. However, drugs have side effects and the control effect varies among individuals.
- Trial name
- NCT06224803
- Testing
- Compound plant extracts, Indigestible dextrin
- Where
- Taiwan
- Volunteers
- 56 people
- Sponsor
- Global Preventive Medicine Biotech Co., Ltd.
Diabetes Mellitus, Type 2
Evaluating Safety of Andiabet on Diabetes Mellitus Type II Patients, Phase I CT.
This phase I clinical trial is used to evaluate the safety of Andiabet, a herbal-derived medicinal product that assists in the treatment of type 2 Diabetes (T2D).
- Trial name
- NCT04930679
- Testing
- Andiabet
- Where
- Vietnam
- Volunteers
- 14 people
- Sponsor
- Centre of Clinical Pharmacology, Hanoi Medical University
Pancreatic Cancer, Chronic Pancreatitis
Biospecimens for Identification of Diseases of the Pancreas.
This proposed project is designed to collect data and specimens from patients/subjects presenting to the University of Michigan with a disease affecting the pancreas (or specific control populations).
- Conditions
- Pancreatic Cancer, Chronic Pancreatitis, Type II Diabetes, Pancreatic Cysts
- Trial name
- SPORE-PANC (NCT01392027)
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 712 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Type II Diabetes
The Effects of Raspberry Leaf Tea on Blood Glucose Control
The aim of the present clinical trial is to assess how raspberry leaf polyphenols impact on postprandial glucose and insulin levels in healthy individuals consuming sucrose.
- Trial name
- RLT (NCT06385626)
- Testing
- Raspberry leaf tea
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Reading
Diabetic Retinopathy
Trial to Assess the Efficacy of Neuroprotective Drugs Administered Topically to Prevent or Arrest Diabetic Retinopathy
To assess whether neuroprotective drugs administered topically (somatostatin and brimonidine) are able to prevent or arrest the development and progression of neurodegenerative changes
- Trial name
- EUROCONDOR (NCT01726075)
- Testing
- COLIRIOBCN070660, Brimonidine
- Where
- 11 sites in Denmark, France and 5 more
- Volunteers
- 450 people
- Sponsor
- BCN Peptides
Type II Diabetes
Mass Balance and Biotransformation of [14C]HSK7653 in Human
A single-center, single-dose, non-randomized, open-label design.
- Trial name
- NCT04540016
- Testing
- [14C]HSK7653
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Non-Proliferative Diabetic Retinopathy, Cataract
Nepafenac Once Daily for Macular Edema - Study 2
The purpose of this study is to demonstrate superiority of Nepafenac Ophthalmic Suspension, 0.3% dosed once daily relative to Nepafenac Vehicle based upon clinical outcomes among diabetic participants following cataract surgery.
- Trial name
- NCT01872611
- Testing
- Nepafenac Ophthalmic Suspension, 0.3%, Vehicle, Prednisolone acetate
- Volunteers
- 819 people
- Sponsor
- Alcon Research
Diabetes Type II
A Pilot Study of the Effects of Diet and Behavioral Interventions on Health in Diabetics
The study is a small pilot, designed to provide data regarding the feasibility and acceptability of conducting such a study on a larger scale.
- Trial name
- SUCCEED (NCT01713764)
- Testing
- Low Carbohydrate Diet, American Diabetes Association Diet, Mindfulness and Positive Affect Skills
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, San Francisco
Kidney Transplant, Diabetes Mellitus, Type 2
Immunosuppression Impact on the Metabolic Control of Kidney Transplant With Pre-Existing Type 2 Diabetes (DM)
Protocol Title: Randomized open label study comparing the metabolic control of first Kidney Transplant recipients with Type 2 Diabetes Mellitus (DM) receiving either Prograf or Neoral as part of a ATG induction, prednisone free…
- Conditions
- Kidney Transplant, Diabetes Mellitus, Type 2, Diabetic Nephropathy
- Trial name
- NCT00296296
- Testing
- Cyclosporin, Tacrolimus, 'Diabetes Education / Management'
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Stanford University
Type II Diabetes
The Efficacy and Safety of PAZ320 on PPG and Insulin Blood Levels in Type II Diabetic Patients
The purpose of this study is to test the efficacy of PAZ320 in diabetic patients.
- Trial name
- PAZ320 (NCT04569214)
- Testing
- PAZ320
- Where
- France
- Sponsor
- Boston Therapeutics