Clinical trials: Diabetes Mellitus II
Diabetes Mellitus, Type 1
Safety/Efficacy Study of Subcutaneously Injected Prandial Insulins Compared to Insulin Lispro Alone in Participants With Type 1 Diabetes Mellitus
The purpose of the study is to compare Humalog (Insulin lispro)-recombinant human hyaluronidase (rHuPH20) or Novolog (Insulin aspart)-rHuPH20 to Humalog (Insulin lispro) for the treatment of Type 1 Diabetes Mellitus (T1DM) in…
- Trial name
- NCT01194245
- Testing
- Insulin lispro, recombinant human hyaluronidase PH20, Insulin aspart
- Where
- 19 sites in United States
- Volunteers
- 135 people
- Sponsor
- Halozyme Therapeutics
Type 2 Diabetes
BioDulse II: The Effect of an Irish Seaweed Protein Extract on Glucose Control in Adults With Type 2 Diabetes
Co-ingesting protein with carbohydrate is an effective way to improve postprandial glucose handling. The investigators have isolated and identified a bioactive protein extracted from seaweed.
- Trial name
- NCT05986253
- Testing
- Seaweed protein, Maltodextrin
- Where
- Ireland
- Volunteers
- 10 people
- Sponsor
- University of Limerick
Gingival Scaling, Metabolic Control
The Effect of Oral Hygiene and Full Mouth Scaling on Metabolic Control in Patients With Type II Diabetes
The aim of the study is to evaluate the effect of non-surgical periodontal therapy, consisting of oral hygiene instruction, full mouth scaling and an antimicrobial rinse on the metabolic control of chronic periodontitis patients…
- Trial name
- NCT01255254
- Testing
- Gingival scaling
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Rambam Health Care Campus
Type 2 Diabetes
Digital Health Navigation for Latino Patients With Type II Diabetes
The goal of this clinical trial is to learn about digital literacy training in adult, Latino patient with type II diabetes. The main question it aims to answer is: Can providing digital literacy training during a hospital…
- Trial name
- NCT06283992
- Testing
- Digital Navigation
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Brigham and Women's Hospital
Diabetes Mellitus, Type II
Safety/Efficacy Study of Subcutaneously Injected Prandial Insulins Compared to Insulin Lispro Alone in Patients With Type 2 Diabetes Mellitus
The purpose of the study was to compare Humalog (insulin lispro)-recombinant human hyaluronidase PH20 (rHuPH20) or Novolog (insulin aspart)-rHuPH20 to insulin lispro for the treatment of Type 2 diabetes mellitus (T2DM) in…
- Trial name
- NCT01194258
- Testing
- Insulin lispro, Insulin aspart, Recombinant human hyaluronidase PH20
- Where
- 22 sites in United States
- Volunteers
- 132 people
- Sponsor
- Halozyme Therapeutics
Diabetes Mellitus, Type 2
Using 32 - Gauge Needles With Lengths of 5 mm and 8 mm on Pain Post-injection, Leak and Blood Glucose
This is a Clinical crossover trial study. In this study, 100 patients with type II diabetes will be selected based on entry and exit criteria, then randomly divided into two equal groups (group "A" and group "B").In the first…
- Trial name
- NCT04460092
- Testing
- 5-mm 32-gauge Insulin needles in the first three days of Intervention, 8-mm 32-gauge Insulin needles in the first three days of Intervention, 5-mm 32-gauge Insulin needles in the last three days of Intervention
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Baqiyatallah Medical Sciences University
Hypertension, Diabetes Mellitus, Type 2
Implementation of a Comprehensive Intervention on Hypertension（HTN） and Type 2 Diabetes Mellitus（DM） at PHC Level
Background: The disease burden of hypertension(HTN) and type 2 diabetes mellitus(DM) is rising rapidly in China.Comprehensive interventions(Implementation strategies for providers and interventions for patients) are critical to…
- Trial name
- NCT05353699
- Testing
- Implementation strategies
- Where
- China
- Volunteers
- 12,648 people
- Sponsor
- National Center for Chronic and Noncommunicable Disease Control and Prevention, China CDC
Diabetic Neuropathies
Differences In The Severity Of Diabetic Neuropathy Based On Electromyography In Type 2 Diabetes Mellitus Patients With And Without Comorbidities
The goal of this clinical trial is to learn the differences severity level of diabetic neuropathy based on electromyelography in type II diabetic patient with and without comorbidities. The main questions of this study: 1.
- Trial name
- DISNEY-T2DM (NCT06573684)
- Testing
- Electromyography
- Where
- Indonesia
- Volunteers
- 78 people
- Sponsor
- Universitas Diponegoro
Diabetic Foot Ulcers
A Clinical Study of the Safety and Efficacy of MEBO Wound Ointment in Subjects With Diabetic Foot Ulcers
The objective of this study is to evaluate the safety and efficacy of MEBO in the treatment of subjects with diabetic foot ulcers (DFUs).
- Trial name
- NCT01070433
- Testing
- MEBO Wound Ointment (MEBO), Standard of Care
- Where
- 9 sites in United States
- Volunteers
- 75 people
- Sponsor
- Skingenix, Inc.
Diabetes Mellitus
Study to Compare Pioglitazone and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia
Efficacy comparison of Pioglitazone, once daily (QD), to Rosiglitazone in participants with Type 2 Diabetes
- Trial name
- NCT00331487
- Testing
- Pioglitazone, Rosiglitazone
- Where
- 67 sites in United States
- Volunteers
- 719 people
- Sponsor
- Takeda
Dyslipidemia Associated With Type II Diabetes Mellitus, Diabetes Mellitus, Type 2
EXpanded Combination of Evolocumab Plus Empagliflozin on Diabetes: EXCEED-BHS3 Trial
Based on the current evidence, empagliflozin could reduce cardiovascular morbidity and mortality in Diabetes Mellitus Type 2 (T2DM).
- Conditions
- Dyslipidemia Associated With Type II Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension Arterial
- Trial name
- EXCEED-BHS3 (NCT03932721)
- Testing
- Evolocumab 140 MG/ML
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- University of Campinas, Brazil
T2DM (Type 2 Diabetes Mellitus)
A Study to Evaluate the Efficacy, Safety, and Tolerability of ASC30 Tablets in Participants With Type 2 Diabetes Mellitus
This randomized, double-blind, placebo-controlled Phase II study is designed to evaluate the efficacy, safety, and tolerability of ASC30 oral tablets formulation in participants with Type 2 Diabetes Mellitus
- Trial name
- NCT07321678
- Testing
- ASC30 tablets
- Where
- 8 sites in United States
- Volunteers
- 100 people
- Sponsor
- Ascletis Pharma (China) Co., Limited
Diabetes Mellitus
Efficacy and Safety Study of TAK-559 in Treating Subjects With Type 2 Diabetes Mellitus
The purpose of this study was to determine the safety and efficacy of TAK-559, once daily (QD), in treating subjects with type 2 diabetes mellitus.
- Trial name
- NCT00762684
- Testing
- TAK-559
- Volunteers
- 8 people
- Sponsor
- Takeda
Type 2 Diabetes With Peripheral Angiopathy
Concurrent Training on Patients With Type-II DM Associated PAD.
This clinical trial aims to analyze the effects of concurrent vs aerobic training on glycemic control, ABI, functional capacity and disease-specific QOL among patients with Type-II DM-associated PAD at baseline \& after 12 weeks…
- Trial name
- NCT06028399
- Testing
- Concurrent Training, Aerobic Training
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Ziauddin University
Hypertension, Diabetes Mellitus, Type 2
A Study on Ca Blocker Versus AII Antagonists in Hypertension With Type 2 Diabetes
The antihypertensive effect of the increased dose of angiotensin II receptor blocker (AII antagonist) is compared with that of the additional combined use of amlodipine in hypertensive patients with Type 2 diabetes mellitus, who…
- Trial name
- NCT00144144
- Testing
- Angiotensin II receptor antagonists, Calcium channel blocker
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Advanced-J
Depression, Postpartum
Type II Diabetes Mellitus in Patients Exposed to Pravastatin and Paroxetine
Type 2 Diabetes (T2DM) is a life-long, chronic condition affecting an individuals' ability to regulate glucose levels in the blood. Diabetes can cause many severe complications if not treated properly.
- Trial name
- NCT01602913
- Testing
- Pravastatin alone, Paroxetine alone, Pravastatin and paroxetine combined
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type 1
MELD-ATG: Phase II, Dose Ranging, Efficacy Study of Anti-thymocyte Globulin (ATG) Within 6 Weeks of Diagnosis of Type 1 Diabetes (T1D)
This study has been set up within the framework of the INNODIA network. INNODIA is a global partnership between 31 academic institutions, 6 industrial partners, a small sized enterprise and 2 patient organizations, bringing their…
- Trial name
- Meld-ATG (NCT04509791)
- Testing
- Anti-Human Thymocyte Immunoglobulin, Rabbit
- Where
- 14 sites in Austria, Belgium and 6 more
- Volunteers
- 114 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Type II Diabetes, Nonalcoholic Fatty Liver
Fatty Liver Study in Patients With Type II Diabetes
The primary objective of this trial is to measure changes in hepatic lipid content using three common alternative therapeutic strategies to improve glycemic control in patients with type 2 diabetes who are not controlled with…
- Trial name
- NCT02365233
- Testing
- DPP4 inhibitor, Pioglitazone, Lantus insulin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Diabetic Kidney Disease, IgA Nephropathy
A Study to Evaluate the Efficacy and Safety of SC0062 in the Treatment of Chronic Kidney Disease
This is a phase II study to investigate the safety, preliminary efficacy and pharmacokinetics of SC0062 capsule in patients with chronic kidney disease (diabetic kidney disease and IgA nephropathy)with albuminuria compared to…
- Trial name
- NCT05687890
- Testing
- SC0062 low dose, SC0062 medium dose, SC0062 high dose
- Where
- China
- Volunteers
- 255 people
- Sponsor
- Biocity Biopharmaceutics Co., Ltd.
Kidney Transplant, Familial Hypercholesterolaemia
Cardiovascular Risk in Children With Chronic Conditions Study
Children living with chronic health conditions face a higher risk of developing cardiovascular diseases than their peers, largely due to the accelerated aging of the heart and blood vessels.
- Conditions
- Kidney Transplant, Familial Hypercholesterolaemia, Type 1 Diabetes Mellitus (T1DM), Type 2 Diabetes Mellitus (T2DM)
- Trial name
- CR3C (NCT07086989)
- Where
- 3 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Semmelweis University