Clinical trials: Diabetes Mellitus Risk
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Prevalence and Risk Evaluation of Diabetic Complications of the Foot in A Large Canadian Population
The study aims to assess foot complications among patients with diabetes in Canada, using patient data collected during diabetes foot assessments performed by the LMC Chiropody Team between February 27, 2018 and April 17, 2019.
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Foot Deformities, Onychauxis
- Trial name
- PEDAL (NCT04327622)
- Where
- Canada
- Volunteers
- 5,084 people
- Sponsor
- LMC Diabetes & Endocrinology Ltd.
Diabetes, Prediabetes
Meta-analyses of the Effect of Tree Nuts on Glycemic Control and Features of the Metabolic Syndrome
Tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamia nuts, pecans, pine nuts, pistachios and walnuts) are an important source of unsaturated fatty acids, vegetable protein, and fibre, as well as minerals, vitamins, and…
- Conditions
- Diabetes, Prediabetes, Dysglycemia, Overweight
- Trial name
- NCT01630980
- Testing
- Tree nuts
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
Diabetes Mellitus, Type 2
Thiazolidinedione Intervention With Vitamin D Evaluation
This study will answer two separate questions. The first question is to test the cardiovascular effects of long-term treatment with rosiglitazone or pioglitazone when used as part of standard of care compared to similar standard…
- Trial name
- TIDE (NCT00879970)
- Testing
- pioglitazone, rosiglitazone, Vitamin D
- Where
- 331 sites in United States, Argentina and 23 more
- Volunteers
- 1,332 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type 2
Effects of Vitamin D3 and Yeast Beta-Glucan Supplementation on Glycemic Control and Cardiovascular Disease Risk in Patients With Type 2 Diabetes
This study is a randomized, double-blind, placebo-controlled trial involving 2,500 individuals aged 40-79 with type 2 diabetes (T2D).
- Trial name
- NCT06861062
- Testing
- Vitamin D3, yeast β-glucan
- Where
- 5 sites in China
- Volunteers
- 2,500 people
- Sponsor
- Huazhong University of Science and Technology
Type 2 Diabetes, High Blood Pressure
Polypill for Prevention of Cardiomyopathy
This study will investigate the utility of a polypill-based strategy for patients with type 2 diabetes mellitus and high risk of heart failure (HF), as assessed via the WATCH-DM risk score.
- Trial name
- PolyPreventHF (NCT06143566)
- Testing
- Polypill, Combined prescription of the individual medications
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetes Mellitus, Type 2
Risk of Hospitalized Infections Among Patients With Type 2 Diabetes Exposed to Oral Antidiabetic Treatment
The purpose of this study is to compare the incidence of hospitalizations for infections among patients with type 2 diabetes mellitus who are new initiators of Saxagliptin and those who are new initiators of Oral Anti-Diabetic…
- Trial name
- NCT01086306
- Volunteers
- 113,505 people
- Sponsor
- AstraZeneca
Diabetes
Clinical Trial to Assess the Effects of Dairy on Insulin Sensitivity and β-Cell Function
The aim of this trial is to evaluate the effects of dairy product consumption on insulin sensitivity and pancreatic β-cell function in men and women at risk for the development of type 2 diabetes mellitus (T2DM) who habitually…
- Trial name
- NCT01936935
- Testing
- Low-fat dairy, Sugar-sweetened beverages
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Provident Clinical Research
Diabetes Mellitus
Walnut Consumption and Diabetes Risk
Multiple NHANES surveys were combined and weighted to evaluate relationships between walnut consumption and type 2 diabetes mellitus using various independent measures of diabetes status and risk.
- Trial name
- NCT03224533
- Testing
- Diabetes Outcome
- Where
- United States
- Volunteers
- 34,121 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Type2 Diabetes, Sleep
Experimental Changes in Children's Sleep Duration and Timing: Effect on Obesity and Type 2 Diabetes Risk
Enhancing children's sleep duration and/or timing may represent a novel approach for weight regulation and prevention of T2DM. The proposed study will assess how experimental changes in children's sleep duration and timing affect…
- Trial name
- NCT02979860
- Testing
- Sleep duration 90 min, Sleep duration 45 min, Sleep timing
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Temple University
Cardiovascular Risk Assessment
Prognosis of Type 2 Diabetic Patients
The study will include 1200 patients with type 2 diabetes and angiographically documented coronary artery disease and 600 matched non-diabetic patients without type 2 diabetes.
- Trial name
- ARTEMIS (NCT01426685)
- Where
- Finland
- Volunteers
- 1,880 people
- Sponsor
- University of Oulu
Impaired Glucose Tolerance, Prediabetic State
Cardiovascular Disease (CVD) Risk and Prevention in Early Glucose Intolerance
The purpose of this study is to determine whether cardiovascular disease (CVD) risk markers, β-cell function, and insulin sensitivity can be improved by targeting mechanisms of both diabetes and CVD - using an antioxidant, an…
- Trial name
- NCT00122447
- Testing
- Aspirin, Alpha lipoic acid, Olmesartan
- Where
- 2 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Emory University
Type 2 Diabetes
Community-integrated Nutrition Education to Prevent Type 2 Diabetes in Peel
The goal of this clinical trial is to assess the effectiveness of an intervention that delivers nutrition education based on the Portfolio Diet on type-2 diabetes (T2D) risk factors among adults who are without chronic…
- Trial name
- NCT07058558
- Testing
- Nutrition Education and Community Gardening
- Where
- 2 sites in Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes, Morbid Obesity
Closed Incision Negative Pressure Wound Therapy vs. Foam as Post Operative Dressing
The primary objective is to assess the frequency of a wound healing complication, in a closed incisional wound in a "high risk" surgical incision when treated with Negative Pressure Wound Therapy versus a highly absorbent…
- Conditions
- Diabetes, Morbid Obesity, Lymphedema, Orthopedic Disorder
- Trial name
- NCT05427916
- Testing
- Avance Solo, Optifoam
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Type 2 Diabetes
The Effect of Nexium and Probiotics on Insulin Secretion and Cardiovascular Risk Factors in Patients With Type 2 Diabetes
To test the effect of Nexium and probiotics on insulin secretion and cardiovascular risk factors on type 2 diabetic patients. Study Hypothesis: 1.
- Trial name
- Nexium (NCT00699426)
- Testing
- nexium, Yoghurt
- Volunteers
- 41 people
- Sponsor
- Lise Tarnow
Type1 Diabetes Mellitus
Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus
The study is a 2-arm, double blinded, multicenter, 2:1 randomized, placebo controlled clinical trial. Subjects will receive hydroxychloroquine or placebo and close monitoring for progression of T1D.
- Trial name
- TN-22 (NCT03428945)
- Testing
- Hydroxychloroquine
- Where
- 51 sites in United States, Australia and 4 more
- Volunteers
- 273 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Giant Cell Arteritis, Polymyalgia Rheumatica
Risk of Diabetes Mellitus in Patients With Giant Cell Arthritis and Polymyalgia Rheumatica.
The goal of this observational study is to expand the knowledge about development and aggreviation of diabetes mellitus in patients with giant cell arthritis and polymyalgia rheumatica.
- Conditions
- Giant Cell Arteritis, Polymyalgia Rheumatica, Large Vessel Vasculitis
- Trial name
- NCT06011512
- Where
- Denmark
- Volunteers
- 198 people
- Sponsor
- Salome Kristensen
Cardiovascular Disease, Diabetes
Soybean Oil Trial of cArdiovascular Risk
The study will determine the effects of different types of soybean oils on biomarkers of risk for cardiovascular disease and diabetes.
- Conditions
- Cardiovascular Disease, Diabetes, Metabolic Syndrome
- Trial name
- STAR (NCT02404207)
- Testing
- Soybean oil, High-oleic soybean oil, High-oleic soybean oil + fully hydrogenated soybean oil
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- USDA Beltsville Human Nutrition Research Center
Type 2 Diabetes Mellitus, Hypercholesterolemia
Atorvastatin, Aspirin, Oxidative Stress, Coagulation and Platelet Activation Indexes
Primary and secondary prevention trials with statins, as well as with antiplatelet, clearly demonstrated that these drugs are able to reduce cardiovascular events.
- Trial name
- NCT01322711
- Testing
- Atorvastatin
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Roma La Sapienza
Periodontitis, Diabetes Mellitus, Type 2
A Danish Nationwide Longitudinal Study on Prevalence of Periodontitis and Its Co-morbidities
The project (PlanPerioMed) is a register-based study evaluating the associations and patterns of health care delivery between periodontitis and medical diseases using data from the Danish dental record system Dentalsuite…
- Conditions
- Periodontitis, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Rheumatoid Arthritis
- Trial name
- PlanPerioMed (NCT05574231)
- Testing
- Periodontal treatment
- Volunteers
- 4,000,000 people
- Sponsor
- University of Copenhagen
Diabetes Mellitus, Type 2
Does Screening of Coronary Artery Disease an Efficient Public Health Strategy in Patients With Type 2 DIABetes
The purpose of SCADIAB is to assess the real-life efficiency of systematic screening for ischemic heart disease in T2DM patients at very high cardiovascular risk, without known coronary heart disease, from the databases of the…
- Trial name
- SCADIAB (NCT04534530)
- Testing
- Systematic screening for ischemic heart disease in type 2 diabetic patients
- Where
- France
- Volunteers
- 90,000 people
- Sponsor
- University Hospital, Bordeaux
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