Clinical trials: Diabetes Mellitus Type II,
Type 2 Diabetes Mellitus
Impacts of PIO/MET Following Short-term Intensive Insulin Treatment in Newly Diagnosed Type 2 Diabetes
Short-term intensive insulin therapy (SIIT) induces glycemic remission in patients with newly diagnosed type 2 diabetes. But remission rate reduces over time.
- Trial name
- NCT03196362
- Testing
- Pioglitazone + Metformin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Diabetic Nephropathies
INNOVATION Study - Telmisartan (Micardis) in Incipient Diabetic Nephropathy
The aim of this study is to compare the preventive effect of Telmisartan(Micardis) versus placebo control on the transition to overt nephropathy in patients with diabetic nephropathy manifesting microalbuminuria associated with…
- Trial name
- NCT00153088
- Testing
- Telmisartan capsule 40 mg, Telmisartan capsule 80 mg
- Where
- 160 sites in Japan
- Volunteers
- 527 people
- Sponsor
- Boehringer Ingelheim
Acute Coronary Syndrome, Diabetes Mellitus, Type 2
Simvastatin and Fenofibrate vs Simvastatin Alone in Patients With Type 2 Diabetes Mellitus and Acute Coronary Syndrome
To test the hypothesis that early (within 5-21 days after index event) administration of combined lipid-lowering therapy in extremely high risk population of patients with type 2 diabetes mellitus (T2DM) and hypertriglyceridemia…
- Conditions
- Acute Coronary Syndrome, Diabetes Mellitus, Type 2, Hypertriglyceridemia
- Trial name
- NCT02015988
- Testing
- Fenofibrate, Simvastatin
- Where
- Ukraine
- Volunteers
- 60 people
- Sponsor
- Koval' O., MD
Type 2 Diabetes Treated With Insulin
A Randomized Trial Evaluating Control-IQ+ Technology in Adults With Type 2 Diabetes
A randomized controlled trial (RCT) to assess the safety and efficacy of use of Control-IQ+ technology in adults with type 2 diabetes using basal-bolus insulin therapy.
- Trial name
- 2IQP (NCT05785832)
- Testing
- t:slim X2 insulin pump with Control-IQ+ technology and Dexcom G6 CGM, Standard Therapy plus continuous glucose monitoring (CGM)
- Where
- 21 sites in United States, Canada
- Volunteers
- 319 people
- Sponsor
- Tandem Diabetes Care, Inc.
Type 2 Diabetes Mellitus
A Surgical Approach to the Management of Type II Diabetes Mellitus in Patients With a BMI Between 25-35 kg/m2
The purpose of the study is to determine if by performing surgery we can cure Type II Diabetes. The surgical procedures: 1. a sleeve gastrectomy, cutting out a portion of the stomach, which provides restriction of caloric intake…
- Trial name
- NCT01197963
- Testing
- Sleeve Gastrectomy and Ileal transposition, dietary and medical management
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The University of Texas Health Science Center, Houston
Diabetes Mellitus Type 2 (T2DM), Artificial Intelligence (AI)
Therapeutic Efficacy and Safety Evaluation of AI in the Management of Diabetes: A RCT Trial
Purpose: To evaluate the efficacy of artificial intelligence (AI)-based decision-making technology in managing glycated hemoglobin (HbA1c) and blood glucose levels compared to the control group.
- Trial name
- NCT06957093
- Testing
- artificial intelligence, Routine diagnosis and treatment group for diabetes
- Where
- China
- Volunteers
- 400 people
- Sponsor
- The First Hospital of Jilin University
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Telemedicine Continuous Remote Monitoring of Adults With Uncontrolled Diabetes Mellitus
The purpose of this single center observational study is to determine the effect of continuous remote continuous glucose monitor (CGM) reporting coupled with a telemedicine intervention (Tele-CGM program) on levels of HbA1C in…
- Trial name
- TELEMTRRDM (NCT05161793)
- Testing
- Tele-Monitor DM
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- University of Southern California
Type 2 Diabetes, Neuropathy
Perioperative Adverse Cardiovascular Event in Type-2 Diabetic Patients
The study was designed to investigate the correlation between perioperative adverse cardiovascular events and the degeneration of sensory nerves in patient diagnosed with type 2 diabetes mellitus, undergoing elective non-cardiac…
- Trial name
- DMPACE (NCT04579406)
- Testing
- non-cardiac surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Hospital of Shanxi Medical University
Positive Regulation of Oxidative Stress Process
A Clinical Trial to Study the Effect of Lycopene in Patients With Gum Disease and type2 Diabetes Mellitus
This study was performed to assess the efficacy of systemic lycopene (8 mgms Daily for two months) as an adjunct to scaling and root planing in chronic periodontitis patients with type 2 diabetes mellitus.
- Trial name
- "SLSRPD" (NCT02263352)
- Testing
- Lycored soft gels Jagsonpal Pharma, Systemic 8mgms/day, Scaling and root planing
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases
Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCl25 mg/5 mg/1000 mg Extended Release Tablet Versus Trijardy® XR 25 mg/5 mg/1000 mg Extended- Release Tablets
An open label, randomized, two-period, two treatment, two-sequence, crossover, balanced, single dose oral bioequivalence study to compare Empagliflozin/ Linagliptin/ Metformin HCl 25 mg/5 mg/1000 mg Extended Release Tablet versus…
- Trial name
- NCT07872358
- Testing
- Empagliflozin/Linagliptin/Metformin HCl Extended Release Tablet, Trijardy® XR Tablets
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Diabetes Type I, Diabetes Type II
Feasibility Study of DermGEN for Diabetic Foot Ulcer Treatment
The purpose of this clinical trial is to perform a limited pilot study to determine the safety and feasibility of DermGEN in the treatment of non-healing diabetic foot ulcers (DFU). This will be a one-arm prospective study.
- Trial name
- NCT02184455
- Testing
- DermGEN
- Where
- 2 sites in Canada
- Volunteers
- 11 people
- Sponsor
- Dr. Paul F. Gratzer
Polyneuropathy
Asian Study on Cilostazol Effectivity in Neuropathies of Diabetes Mellitus Type 2-A Pilot Study in the Philippines
To describe if there are differences in the subjective, objective and electrophysiologic parameters of diabetic polyneuropathies at baseline, four (4) weeks, eight (8) weeks, and twelve (12) weeks after Cilostazol therapy.
- Trial name
- ASCEND (NCT01076478)
- Testing
- Cilostazol
- Where
- Philippines
- Volunteers
- 47 people
- Sponsor
- Otsuka Pharmaceutical, Inc., Philippines
Diabetes Mellitus, Type 2, Cystic Fibrosis
Redox Imbalance and the Development of Cystic Fibrosis Diabetes
Cystic fibrosis-related diabetes (CFRD) occurs in almost 20% of teens and 50% of adults. The investigators' long term goal is to determine the cause of CFRD in order to translate this knowledge into therapies aimed at preventing…
- Trial name
- Redoxy (NCT02202876)
- Testing
- Oral Glucose Tolerance Test, High Glycemic Index Meal, Low Glycemic Index Meal
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Emory University
Depression, Type 2 Diabetes Mellitus
Participatory Design of Patient-centered Depression and Diabetes Care
The burden of diabetes is anticipated to grow yet the proportion of adults whose diabetes is controlled is decreasing over time.
- Trial name
- NCT02178176
- Testing
- Education, encouragement, card sort, Education, encouragement
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Pennsylvania
Diabetes, Diabetes Mellitus, Type 1
Paediatric Subjects - Special Survey
This study is conducted in Japan. The aim of this study is to collect safety and efficacy data when using insulin aspart in children with diabetes under normal clinical practice conditions.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT01538576
- Testing
- insulin aspart
- Where
- Japan
- Volunteers
- 71 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus, Overweight
Dietary Calcium Supplementation, Gut Permeability and Microbiota in Type 2 Diabetics
Dietary calcium seems to act on glycemic control, favoring the prevention and treatment of type 2 diabetes mellitus (DM2). It is possible that calcium modulates gut microbiota and increase the integrity of the intestinal mucosa.
- Trial name
- NCT02377076
- Testing
- Dietary calcium supplementation, Control
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Federal University of Vicosa
Diabetes, Diabetes Mellitus, Type 2
Non-Interventional Study on Safety of Liraglutide in Subjects With Type 2 Diabetes
This trial is conducted in Asia. The aim of this trial is to investigate the safety profile of liraglutide under normal conditions of use.
- Trial name
- Lead-Ph (NCT01345734)
- Testing
- liraglutide
- Where
- Philippines
- Volunteers
- 1,056 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes, Emotions
Boosting Emotions & Happiness in Outpatients Living With Diabetes: Phase I
The focus of this study is to examine the feasibility, acceptability, and preliminary impact of a customized, combined positive psychology and motivational interviewing (PP-MI) health behavior intervention in a group of patients…
- Conditions
- Type 2 Diabetes, Emotions, Patient Compliance
- Trial name
- BEHOLD-16 (NCT03001999)
- Testing
- PP-MI health behavior intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus, Type 2
T2 FSL2 Weight Loss
To compare the impact of the FreeStyle Libre (FSL) 2 Flash Glucose Monitoring System to the current Diabetes Monitoring standard of care (SOC) on weight reduction in subjects with type 2 diabetes.
- Trial name
- NCT05168306
- Testing
- FreeStyle Libre 2 Flash Glucose Monitoring System
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Abbott Diabetes Care
Type 2 Diabetes
High-Protein Diets and Diabetes
High-protein (HP) diets are popular and evidence indicates they are more likely to be adhered to and produce more sustained weight loss, particularly under ad libitum conditions.
- Trial name
- HPD (NCT05615558)
- Testing
- Dietary Intervention
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University of Exeter
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