Clinical trials: Diabetes Mellitus Type II,
Type 2 Diabetes
Comparison of the Efficacy and Safety Between Pioglitazone and Placebo Added to Combination Therapy in Type 2 Diabetes
The purpose of this trial is to study the efficacy and safety of pioglitazone added to combination therapy of sulfonylurea plus metformin with placebo in patients with type 2 diabetes.
- Trial name
- NCT00991055
- Testing
- Pioglitazone
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
Type 2 Diabetes Treated With Insulin
Effect on HbA1c of the Initiation of CGM in Adults With Type 2 Diabetes Treated With Basal Insulin in Finland
The goal of this clinical study is to determine the impact of starting the use of the FreeStyle Libre 2 glucose monitoring system, over a three month period, on HbA1c in adults with type 2 diabetes treated with a basal insulin…
- Trial name
- NCT06268821
- Testing
- FreeStyle Libre 2 Flash Glucose Monitoring System
- Where
- 2 sites in Finland
- Volunteers
- 11 people
- Sponsor
- Abbott Diabetes Care
Type 2 Diabetes
Percutaneous CT-guided Cryoablation of the Splanchnic Nerves
The purpose of this study is to evaluate the safety and effectiveness of freezing (cryoablation) of the splanchnic nerve for management of diabetes.
- Trial name
- NCT04569721
- Testing
- CT Guided Splanchnic Cryoablation
- Where
- United States
- Sponsor
- Emory University
Type 2 Diabetes Mellitus
Fatty Acid Binding Protein 2 (FABP2) Ancillary Proposal
TITLE: CSP 465-C, Fatty Acid Binding protein 2 (FABP2) ancillary proposal to CSP# 465 Glycemic Control and Complications in Diabetes Mellitus Type 2. Angeliki Georgopoulos, M.D. Carlos Abraira M.D. William Duckworth M.D.
- Trial name
- NCT00256633
- Where
- 16 sites in United States, Puerto Rico
- Volunteers
- 874 people
- Sponsor
- US Department of Veterans Affairs
Type 2 Diabetes
Long-term Safety Study of Vildagliptin in Patients With Type 2 Diabetes
This study is designed to demonstrate the long-term safety of vildagliptin in patients with type 2 diabetes. This study will study vildagliptin as add-on therapy with metformin, thiazolidinedione, α-glucosidase inhibitor (α-GI)…
- Trial name
- NCT01159249
- Testing
- Vildagliptin
- Where
- 24 sites in Japan
- Volunteers
- 245 people
- Sponsor
- Novartis Pharmaceuticals
COVID-19, Type 2 Diabetes Mellitus
Effects of Telerehabilitative Aerobic and Relaxation Exercises Patients With Type 2 Diabetes With and Without COVID-19
Type-2 Diabetes Mellitus (DM) disease, like other chronic diseases, is a group of diseases that are adversely affected by the COVID-19 pandemic.This study was planned to examine the effect of COVID-19 disease on patients with…
- Trial name
- NCT05411458
- Testing
- Aerobic and Relaxation Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bozyaka Training and Research Hospital
Type 2 Diabetes Mellitus
Effect of BKR-013 on Average Daily Glucose Levels
The purpose of this study is to evaluate the effect of BKR-013 on average daily glucose (ADG) levels in type 2 diabetes (T2D) subjects during 28 days of either placebo or active test product administration.
- Trial name
- NCT03382015
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- BioKier Inc.
Type 2 Diabetes Mellitus
A Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ZYD1, Following Subcutaneous Administration in Healthy Volunteers
ZYD1 is a novel GLP-1 receptor agonist. The ZYD1 exhibits increased stability to proteolytic cleavage, especially against dipeptidyl peptidase-4 (DPP-IV). ZYD1 is a potent antidiabetic agent without gastrointestinal side-effects.
- Trial name
- ZYD1 (NCT01972893)
- Testing
- ZYD1
- Where
- India
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Zydus Lifesciences Limited
Type 2 Diabetes
Impact of Exenatide on Cardiovascular Exercise Performance in Type 2 Diabetes
Previous research in our lab and others has established that type 2 diabetes (T2D) is associated with significantly impaired functional exercise capacity, a factor which is potentially associated with an increased risk of…
- Trial name
- Exenatide (NCT01364584)
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Colorado, Denver
Type 2 Diabetes
Effects of Whey Protein in Type 2 Diabetics
The objectives of this study are to examine the effects of chronic, (12 weeks) administration of Whey protein on HbA1c, and postprandial glucose (PPG).
- Trial name
- WHEY-T2D (NCT01944449)
- Testing
- Whey Protein (WPC) at breakfast, Other Protein Sources at breakfast, Low Protein at breakfast
- Where
- 2 sites in Israel, Venezuela
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
Type 2 Diabetes Mellitus, Insulin Sensitivity/Resistance
The Effect of Exercise on Gut Microbiota in Type 2 Diabetic Patients
To investigate whether targeted lifestyle intervention (exercise), induces a change in intestinal fecal microbiota related to improved glycemic control and systemic inflammation in patients with DM type 2.
- Trial name
- NCT03380338
- Testing
- Combined aerobic and strength exercise
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Amsterdam UMC, location VUmc
Type 2 Diabetes Mellitus
An Observational Study of Type II Diabetics Treated With Dual Therapy With or Without Sitagliptin (Januvia®/Xelevia®, MK-0431-201)
This is an observational study to compare the effectiveness of dual therapy of Type II diabetes mellitus with metformin + sitagliptin versus metformin + a sulfonylurea in routine clinical practice in France.
- Trial name
- NCT01357135
- Testing
- Metformin, Sitagliptin, Sulfonylurea
- Volunteers
- 3,453 people
- Sponsor
- Merck Sharp & Dohme LLC
Schizophrenia, Diabetes Mellitus, Type 2
Naltrexone-Bupropion Versus Placebo-Bupropion for Weight Loss in Schizophrenia
The purpose of this study is to determine the efficacy of combining open-label extended release bupropion (flexible dosing up to 450mg target) and naltrexone (37.5mg) versus Bupropion and placebo along with a daily 500 calorie…
- Conditions
- Schizophrenia, Diabetes Mellitus, Type 2, Obesity
- Trial name
- NBC (NCT03132571)
- Testing
- Naltrexone, Bupropion
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Yale University
Periodontitis, Type 2 Diabetes Mellitus
FM-SRP and Tooth Extraction Improve Type 2 Diabetes Mellitus in Periodontitis
This intervention study is designed to evaluate the effects of non-surgical procedure in addition to surgical procedure on systemic inflammation and glycemic control in with type 2 diabetes mellitus patients with periodontitis in…
- Trial name
- NCT02874963
- Testing
- Surgical Periodontal Treatment, Non Surgical Periodontal Treatment includes scaling root planing with UDS-J Ultrasonic Scaler., Non Surgical Periodontal Treatment includes post operative mouth wash with Listerine® (ethanol 21.6%, methyl salicylate 0.06%, menthol 0.042%, thymol 0.064% and eucalyptol 0.092%)
- Where
- Kosovo
- Volunteers
- 160 people
- Sponsor
- University Clinical Centre of Kosova
Type 2 Diabetes, Cardiovascular Risk
Different Insulin Regimens and Postprandial Coagulation Activation
The purpose of this study in patients with type 2 diabetes was to investigate the acute effect of postprandial blood glucose levels modified by two different insulin treatment regimens on coagulation activation, inflammation and…
- Conditions
- Type 2 Diabetes, Cardiovascular Risk, Hemostasis, Inflammation
- Trial name
- NCT01053234
- Testing
- Standardised meals
- Where
- Denmark
- Volunteers
- 78 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Diabetes, Diabetes Mellitus, Type 2
A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Japanese Subjects With Type 2 Diabetes Mellitus.
This trial is conducted in Asia. The aim of this trial is to compare the efficacy and safety of insulin degludec/liraglutide, insulin degludec and liraglutide in Japanese subjects with type 2 diabetes mellitus.
- Trial name
- DUAL™ I Japan (NCT02607306)
- Testing
- insulin degludec/liraglutide, insulin degludec, liraglutide
- Where
- 76 sites in Japan
- Volunteers
- 819 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus Type 2
Effect of Linagliptin in Comparison With Glimepiride as Add on to Metformin on Postprandial Beta Cell Function, Postprandial Metabolism and Oxidative Stress in Patients With Type 2 Diabetes Mellitus
The goal of this mechanistic study is to investigate the effect of Linagliptin in comparison to Glimepiride as add on therapy on several parameters characterizing postprandial metabolism and oxidative stress in type 2 diabetic…
- Trial name
- NCT01547104
- Testing
- Linagliptin, Glimepiride
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Marcus Borchert
Diabetes Mellitus, Type 2
Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
This study aims to assess the effect and breakdown of lysine administration, specifically examining whether it leads to increased plasma 2-AAA in healthy humans.
- Trial name
- NCT05210504
- Testing
- L-Lysine, Normal Saline
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Diabetes Type 2, Obesity
I-care: Stimulating Self-management in Patients With Type 2-diabetes
The overall objective of this pilot study is to develop a cost-effective treatment methodology delivered outside of traditional clinical setting, and based on modern technology for patients with diabetes type 2 also suffering…
- Trial name
- I-care (NCT01297049)
- Testing
- Cognitive behavior therapy (CBT)
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo Metropolitan University
Type 2 Diabetes Mellitus, Arteriosclerosis Obliterans
Study of Cilostazol and Probucol to Assess Their Effects on Atherosclerosis Related Biomarker
1. To evaluate the efficacy of Cilostazol and Probucol alone and in combination on atherosclerosis related biomarker 2. To evaluate the safety of Cilostazol and Probucol alone and in combination on atherosclerosis related…
- Trial name
- NCT00823849
- Testing
- Cilostazol, Probucol, Cilostazol+Probucol
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Otsuka Beijing Research Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.