Clinical trials: Diabetes Mellitus Type II,
Metabolic Syndrome, Type 2 Diabetes
Lifestyle Intervention for Pakistani Women in Oslo
Immigrants from South Asia in Norway have a high prevalence of type 2 diabetes and conditions related to the metabolic syndrome. It has been documented that these conditions may be prevented by changes in lifestyle.
- Trial name
- InnvaDiab (NCT00425269)
- Testing
- lifestyle intervention (diet and physical activity)
- Where
- Norway
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Diabetes Mellitus, Type 2, Metabolic Syndrome
Isomaltulose VS Sucrose - Postprandial Effect on Incretin Profile and Second Meal Effect
This study evaluates the different postprandial effect of isomaltulose and sucrose on the incretin profile and as an determinant for the second meal effect.
- Trial name
- NCT03806920
- Testing
- Intervention A, Intervention B, Intervention C
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Diabetes, Diabetes Mellitus, Type 2
Comparison of Repaglinide and Gliclazide in Chinese Subjects With Type 2 Diabetes Never Received Oral Antidiabetic Drug Treatment
This trial is conducted in Asia. The aim of this clinical trial is to investigate the blood glucose lowering effect and the safety profile of repaglinide given alone compared to gliclazide given alone in Chinese subjects with…
- Trial name
- NCT01022762
- Testing
- repaglinide, gliclazide
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Novo Nordisk A/S
Diabetic Foot, Type 2 Diabetes Mellitus With Established Diabetic Nephropathy
The Effectiveness of Improving Self-care After Counseling for the Diabetics Mellitus Foots Around Chiayi Region
Objectives: Preventing diabetic foot problems (DFP) and associated consequences, such as amputation, is a critical in rural regions.
- Trial name
- NCT01299246
- Testing
- Michigan Neuropathy Screening Instrument
- Where
- Taiwan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Diabetes, Diabetes Mellitus, Type 2
Diabetes Companion App for Adults With Diabetes and Their Carers
Diabetes self-management support, education, and training are increasingly being delivered through digital technology such as mobile phones.
- Conditions
- Diabetes, Diabetes Mellitus, Type 2, Diabetes Mellitus, Diabetes Type 2
- Trial name
- NCT05535842
- Testing
- GLOW
- Where
- 2 sites in Singapore
- Volunteers
- 224 people
- Sponsor
- Nanyang Technological University
Diabete Type 2
Which is Better to Start With DPP-4 Inhibitors or SGLT-2 Inhibitors in Egyptian Diabetic Patients?
Our trial goal is to determine the efficacy and safety of sitagliptin in comparison with empagliflozin in type 2 diabetic Egyptian patients.
- Trial name
- NCT05359341
- Testing
- Sitagliptin 50 mg, Empagliflozin 12.5 MG, Sitagliptin 50 mg + Empagliflozin 12.5 MG
- Where
- Egypt
- Volunteers
- 175 people
- Sponsor
- Sadat City University
Diabetes
Study of BMS-477118 as Monotherapy With Titration in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
The purpose of this trial is to understand if saxagliptin is more effective than placebo as a treatment for type 2 diabetic subjects who are not controlled with diet and exercise
- Trial name
- NCT00316082
- Testing
- Saxagliptin, metformin
- Where
- 74 sites in United States, India and 2 more
- Volunteers
- 365 people
- Sponsor
- AstraZeneca
Diabetes
Eversense® Non-adjunctive Use Post Approval Study
This is a non-blinded, prospective, multi-center, single arm longitudinal cohort study (patient serving as their own control), to evaluate the effectiveness of diabetes with the Eversense CGM System non-adjunctively compared to…
- Trial name
- NA-PAS (NCT04836546)
- Testing
- Blood glucose meter, Eversense CGM System
- Where
- 23 sites in United States
- Volunteers
- 925 people
- Sponsor
- Senseonics, Inc.
Angina Pectoris, Coronary Artery Disease
A Study on the Effects of Ranolazine on Exercise Duration in Subjects With Chronic Stable Angina and Coronary Artery Disease (CAD) With Type 2 Diabetes Mellitus (T2DM)
This study will evaluate the efficacy of ranolazine compared to placebo on duration of exercise assessed by exercise tolerance testing (ETT) at anticipated peak ranolazine plasma concentration after 12 weeks of treatment in…
- Conditions
- Angina Pectoris, Coronary Artery Disease, Type 2 Diabetes Mellitus
- Trial name
- NCT01334203
- Testing
- Ranolazine
- Sponsor
- Gilead Sciences
Diabetic Retinopathy
A Study to Investigate the Efficacy and Safety of RG7774 in Patients With Diabetes Mellitus Type 1 or Type 2 With Treatment-Naive Diabetic Retinopathy
The study's main purpose is to asses the safety, tolerability, and effect of oral administration of RG7774 on the severity of diabetic retinopathy (DR) in participants with moderately severe to severe non-proliferative diabetic…
- Trial name
- CANBERRA (NCT04265261)
- Testing
- RG7774
- Where
- 68 sites in United States, Australia and 5 more
- Volunteers
- 139 people
- Sponsor
- Hoffmann-La Roche
Diabetes Mellitus, Type II
Empagliflozin Reduces Progression of Diabetic Retinopathy in Patients With High Risk of Diabetic Macular Edema
This is a prospective, randomized, active control, two-arm parallel, double-blind, monocenter phase IV clinical trial. The trial compares empagliflozin to glimepiride in patients with type 2 diabetes mellitus in addition to…
- Trial name
- NCT02985242
- Testing
- Empagliflozin, Glimepiride
- Where
- Germany
- Volunteers
- 6 people
- Sponsor
- Hannover Medical School
Dry Mouth, Xerostomia
"Hyaluronan" Formulation for Type 2 Diabetic Patients With Dry Mouth
An increased incidence of dental caries in association with poorly controlled diabetes has also been reported, Xerostomia (dry mouth) has been reported to be a common complaint of patients with diabetes, Without adequate saliva…
- Conditions
- Dry Mouth, Xerostomia, Type 2 Diabetics
- Trial name
- NCT03281486
- Testing
- HA formulation Oral Spray
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- You First Services
Type 2 Diabetes, Microvascular Dysfunction
Less Invasive Detection and Treatment of Very Early Coronary Artery Disease in Patients With Diabetes Mellitus
This protocol focuses on the development of a noninvasive method of early coronary artery disease detection in diabetes. The overall hypothesis is that risk factors for the metabolic syndrome will predict invasive findings on…
- Trial name
- NCT00797186
- Testing
- Intensive risk factor management
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Virginia
Type 2 Diabetes Mellitus, Fear of Hypoglycemia
Effects of a Health Intervention on Fear of Hypoglycemia : a Pilot Study
The purpose of this study was to construct a Fear of Hypoglycemia(FoH) intervention program for type 2 diabetic patients based on the Behaviour Change Wheel (BCW) theory and to investigate the feasibility, acceptability, and…
- Conditions
- Type 2 Diabetes Mellitus, Fear of Hypoglycemia, Health Education, Impaired Awareness of Hypoglycemia
- Trial name
- NCT06197360
- Testing
- Based on BCW Theory of Health Education, General diabetes health education
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yangzhou University
Periodontal Diseases, Gingival Diseases
Asprosin and Total Antioxidant/Oxidant Status in Diabetes and Periodontal Disease
The goal of this observational study is to learn about how different periodontal health status affects the levels of asprosin (a hormone) and total oxidant/antioxidant status in the gingival crevicular fluid and blood serum of…
- Conditions
- Periodontal Diseases, Gingival Diseases, Type 2 Diabetes
- Trial name
- NCT07691060
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Type 2 Diabetes, Hypogonadism
Reandron in Diabetic Men Witn Low Testosterone Level
In men with type 2 diabetes, low testosterone levels have been associated with insulin resistance, truncal obesity and symptoms such as fatigue and erectile dysfunction.
- Trial name
- NCT00613782
- Testing
- Reandron 1000
- Where
- Australia
- Volunteers
- 88 people
- Sponsor
- Austin Health
Smoking Cessation, Diabetes Type 2
Diabetes and Smoking Cessation: a Gender-Oriented Study
People with diabetes still smoke at equivalent rates as non-diabetics. There is lack of evidence regarding interventions for smoking cessation among individuals with diabetes.
- Trial name
- DiSCGO (NCT03426423)
- Testing
- Behavioral smoking cessation intervention, Control
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Carole Clair
Diabetes Mellitus, Type II, Insulin Resistance
Rosiglitazone to Reverse Metabolic Defects in Diabetes
This study will examine whether the anti-diabetes medicine rosiglitazone can safely and effectively reverse the early problems of type 2 diabetes and delay the onset of disease in people with pre-diabetes.
- Trial name
- NCT00094796
- Testing
- Exercise cardiopulmonary metabolic testing, Skeletal muscle biopsy, Brachial artery reactivity testing
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Diabetes Mellitus, Vitamin D Deficiency
Effect of Vitamin D Supplementation on Hemoglobin A1c
This is a prospective, randomized, non-blinded interventional study that will investigate the effect of a vitamin D supplement on HbA1c in patients with uncontrolled type 2 diabetes mellitus (DM) and vitamin D deficiency.
- Trial name
- NCT01354262
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Ascension Health
Obesity & Overweight, Type 2 Diabetes
Hydration Intervention to Decrease Side Effects Associated With GLP - 1 RA Therapy
This is a 17 - week study consisting of a one - week run - in period and a 16 - week intervention. The 16 - week pilot interventions aims to increase hydration in those beginning GLP - 1 RA therapy.
- Conditions
- Obesity & Overweight, Type 2 Diabetes, Type 2 Diabetes (Adult Onset), Obesity Type 2 Diabetes Mellitus
- Trial name
- NCT07641361
- Testing
- Hydration Plus, Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- State University of New York at Buffalo
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