Clinical trials: Diabetes Mellitus Type II,
Type 2 Diabetes Mellitus
Comparison of Nutritional Products for People With Type 2 Diabetes
Part A: To compare the glucose and insulin responses of a standard tube feeding product to that of a diabetes-specific tube feeding product in individuals with type 2 diabetes.
- Trial name
- NCT00520065
- Testing
- enteral nutritional formula, Diabetes specific enteral product
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Abbott Nutrition
Diabetes Mellitus, Type 2, Diabetes Mellitus
Efficacy and Safety of Insulin Lispro Biphasic 25 Compared to Humalog® Mix 25 in Type 2 Diabetes Mellitus Patients
The study is designed to approve non-inferior efficacy and safety of Insulin Lispro Biphasic 25 ("Geropharm") compared to Humalog® Mix 25 in Type 2 Diabetes Mellitus Patients.
- Trial name
- NCT04023344
- Testing
- Humalog Mix25, Insulin Lispro Biphasic 25
- Where
- 18 sites in Russia
- Volunteers
- 210 people
- Sponsor
- Geropharm
Diabetes, Diabetes Mellitus, Type 2
Comparison of NN1250 Versus Insulin Glargine in Subjects With Type 2 Diabetes
This trial is conducted in Asia and Japan. The aim of this trial is to compare insulin degludec (NN1250) with insulin glargine both combined with oral antidiabetic drugs (OADs) in subjects with type 2 diabetes never treated with…
- Trial name
- BEGIN™ (NCT01059799)
- Testing
- insulin degludec, insulin glargine
- Where
- 53 sites in Hong Kong, Japan and 4 more
- Volunteers
- 435 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes
The Effectiveness of Resistance Exercise for Glycemic Control in Type 2 Diabetes Mellitus Patients
Resistance exercise is effective in improving glycemic control in diabetes patients. The effectiveness of a home-based resistance exercise program has not been establish.
- Trial name
- RE (NCT01387334)
- Testing
- Resistance Exercise Training Program With Rubber Bands
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Diabetes Mellitus, Type 2
A Study to Evaluate the Efficacy and Safety of the Addition of Canagliflozin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin and Sitagliptin
The purpose of this study is to assess the effect of canagliflozin (JNJ-28431754) compared to placebo in the treatment of participants with Type 2 Diabetes Mellitus (T2DM), who have inadequate glycemic control on maximally or…
- Trial name
- NCT02025907
- Testing
- Canagliflozin, 100 mg, Canagliflozin, 300 mg
- Where
- 57 sites in United States, Australia and 3 more
- Volunteers
- 218 people
- Sponsor
- Janssen Research & Development, LLC
Pancreatogenic Diabetes Mellitus, Type 2 Diabetes Mellitus (T2DM)
Assessment of Pancreatic Dysfunction in Patients With Type 2 Diabetes
The goal of this observational study is to better understand how the pancreas works in adults with type 2 diabetes. The study focuses on both hormone production (endocrine function) and digestive function (exocrine function) of…
- Conditions
- Pancreatogenic Diabetes Mellitus, Type 2 Diabetes Mellitus (T2DM), Exocrine Pancreatic Insufficiency (EPI)
- Trial name
- T3cDM-AKT (NCT07512934)
- Where
- Kazakhstan
- Volunteers
- 310 people
- Sponsor
- West Kazakhstan Marat Ospanov Medical University
Cognitive Decline, Aging
Dietary Reduction of AGEs to Prevent Cognitive Decline in Elderly Diabetics
Basic science and observational human studies suggest that high conentrations of circulating Advanced Glycation End-products (AGEs) may promote cognitive decline in older adults.
- Conditions
- Cognitive Decline, Aging, Type 2 Diabetes
- Trial name
- NCT02739971
- Testing
- Low AGEs diet, Standard of care dietary guidance for Type 2 diabetes
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Sheba Medical Center
Type 2 Diabetes
A Clinical Study of Insulin Degludec Injection in Subjects With Type 2 Diabetes
This study is a multi-center, randomized, open-label, parallel, positive-controlled registered clinical study,to evaluate the efficacy and safety of insulin degludec injection developed by Chia Tai Tianqing Pharmaceutical Group…
- Trial name
- NCT04955834
- Testing
- Insulin degludec injection, Tresiba®
- Where
- 2 sites in China
- Volunteers
- 344 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Diabetes Mellitus, Type 2, Diabetes
Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide
This study is to investigate how adipocyte (fat cell) function and fat distribution differ between individuals with normal-weight type 2 diabetes (NWD), those with overweight type 2 diabetes (OWD), and normal-weight controls…
- Conditions
- Diabetes Mellitus, Type 2, Diabetes, Type 2 Diabetes, Pre Diabetes
- Trial name
- NCT06657209
- Testing
- Insulin resistance testing, OGTT, Fat biopsy
- Where
- 2 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Stanford University
Diabetes Mellitus, Type 2
Determining the Effect on Patients of Internet-Based Diabetes Disease Management
This grant supports a 12-month randomized controlled trial comparing usual care versus collaborative disease management over the Internet among disadvantaged African-Americans with Type 2 diabetes.
- Trial name
- NCT00220207
- Testing
- Internet co-management module
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Robert Wood Johnson Foundation
Diabetes Type 2, Diabetic Neuropathies
High vs Low Dose Vitamin D in Patients With Diabetic Peripheral Neuropathy
Aim. To assess the effect of different doses of vitamin D supplementation on peripheral neuropathy in patients with type 2 diabetes mellitus (T2DM).
- Conditions
- Diabetes Type 2, Diabetic Neuropathies, Vitamin D Deficiency
- Trial name
- NCT04377399
- Testing
- Vitamin D
- Where
- Russia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Type 2 Diabetes
Validation Study for the Alertgy Non-invasive Continuous Glucose Monitor (ANICGM)
Diabetes mellitus (DM) affects 30 million people in the United States. To achieve glucose control, most patients are prescribed glucose meters by their physicians.
- Trial name
- NCT04166032
- Testing
- Alertgy non-invasive continuous glucose monitoring device (ANICGM)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Cleveland Clinic
Diabetes
Comparing the Effect of Structured Care Versus Usual Care in Type 2 Diabetes Patients Across the Asia Pacific Region
In this demonstration project (Asia Pacific JADE and DIAMOND Program, AP-JD in short) supported by the Asia Diabetes Foundation (ADF), patients will be recruited from different sites across Asia, with each site recruiting at…
- Trial name
- AP-JD (NCT01631084)
- Testing
- JADE, DIAMOND
- Where
- Hong Kong
- Volunteers
- 20,834 people
- Sponsor
- Asia Diabetes Foundation
Diabetes Mellitus
Effect of Exenatide on Abdominal Fat Distribution in Patients With Type 2 Diabetes Pretreated With Metformin
A multicenter, randomized, double-blind, placebo-controlled trial will assess the effects of twice-daily subcutaneous injection with exenatide versus treatment with matching placebo injection on abdominal visceral fat content.
- Trial name
- NCT00701935
- Testing
- exenatide
- Where
- 17 sites in United States, Canada
- Volunteers
- 80 people
- Sponsor
- AstraZeneca
Type 2 Diabetes Mellitus (T2DM)
Spiritual Care for Psychological and Glycemic Outcomes in Type 2 Diabetes
This study aims to evaluate the effects of integrating spiritual care into the management of patients with type 2 diabetes mellitus.
- Trial name
- SC-DMT2 (NCT07333625)
- Testing
- Spiritual Care Program, Standard Diabetes Care
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Noor Huda Mustofa
Type2 Diabetes
Initiating Mealtime Ultra-Rapid Acting Insulin (Afrezza) in Uncontrolled Type 2 Diabetes Patients
To examine the effects of adding prandial Afrezza inhaled insulin to patients with type 2 diabetes who are not controlled after at least 6 months of other diabetes treatments including oral agents, basal insulin, or GLP-1 use.
- Trial name
- NCT03324776
- Testing
- Afrezza Inhalant Product
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Model Clinical Research LLC
Obesity and Type 2 Diabetes, Diet Modification
Mobile Regulation of Craving Training (mROC-T) to Improve Dietary Intake in Rural Adolescent Girls
The goal of this clinical trial is to test if a regulation of craving training intervention in the form of a mobile phone app can increase fruit and vegetable intake in adolescent girls ages 14-18 years of age.
- Trial name
- ROC Teens! (NCT06723028)
- Testing
- Regulation of craving training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Cardiovascular Disease, Type 2 Diabetes
Health2006 - an Observational Study of Cardiovascular Disease, Diabetes, Asthma and Allergy
The aim is to assess the population prevalence of risk factors for different chronic diseases such as cardiovascular disease, type 2 diabetes, osteoporosis, asthma, and allergy.
- Conditions
- Cardiovascular Disease, Type 2 Diabetes, Asthma, Hypersensitivity
- Trial name
- NCT00316667
- Where
- Denmark
- Volunteers
- 3,471 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Type 2 Diabetes
A Pharmacokinetic Study Comparing the Liraglutide Injection (RD12014) and Victoza® in Healthy Chinese Subjects
To evaluate the pharmacokinetics similarity between the liraglutide injection (RD12014) produced by Sunshine Lake Pharma Co., Ltd.
- Trial name
- NCT05294536
- Testing
- Liraglutide injection,RD12014, Liraglutide injection,Victoza
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Type 2 Diabetes Mellitus
Study of Multiple Oral Doses of PF-07081532 in Adult Participants With Type 2 Diabetes Mellitus
This is a Phase 1, randomized, placebo-controlled, double-blind (investigator- and participant-blinded), sponsor-open study of PF-07081532.
- Trial name
- NCT05158244
- Testing
- PF-07081532
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Pfizer
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