Clinical trials: Diabetes Mellitus Type II,
Diabetes Mellitus Type 2
Technology Intervention for Diabetes Engagement & Self-Care (TIDES)
The purpose of this 3 site, 24-week, Comparative Effectiveness Randomized Clinical Trial in Primary Care is to compare usual care to an online, multi-media, digital intervention for Persons with Type 2 Diabetes to Improve…
- Trial name
- TIDES (NCT01440530)
- Testing
- Educational Intervention, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 170 people
- Sponsor
- Geisinger Clinic
Diabetes
A VI-0521 Study to Evaluate the Long-term Safety and Efficacy in Type 2 Diabetic Adults
The purpose of the study is to determine the long-term safety and efficacy of VI-0521 (phentermine/topiramate) compared to placebo in providing blood sugar control in Type 2 diabetic adults. Continuation of initial 6 month trial.
- Trial name
- NCT00600067
- Testing
- Phentermine/Topiramate
- Where
- 9 sites in United States
- Volunteers
- 130 people
- Sponsor
- VIVUS LLC
Type 2 Diabetes Mellitus
A Clinical Study to Evaluate Renal Hemodynamic Responses to Aliskiren in Patients With Type 2 Diabetes Mellitus
The study objective was to assess the effect of single and multiple doses of aliskiren on renal plasma flow, glomerular filtration rate and to compare the effects of single and multiple doses of aliskiren versus captopril or…
- Trial name
- NCT00660309
- Testing
- Aliskiren, Irbesartan, Captopril
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Novartis
Type 2 Diabetes Mellitus (T2DM), Cognitive Function
Prediabetes and Type 2 Diabetes in Aging
This case-control study will evaluate the effects of geriatric individuals on cognitive status, physical function and fatigue. Our study aims to compare the effects of geriatric individuals with prediabetes and type 2 diabetes…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Cognitive Function, Dual Task, Fatigue
- Trial name
- NCT06953609
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Uşak University
Type II Diabetes Mellitus
Effects of Krill Oil on Endothelial Function in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the effects of krill oil supplementation in patients with Type 2 diabetes mellitus on heart health and laboratory diabetic measurements.
- Trial name
- NCT02091193
- Testing
- Krill Oil (Supplement A)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Danbury Hospital
Type 2 Diabetes
Virtual Diabetes Care for Adults With Type 2 Diabetes on Medicaid and Insulin Therapy
This 12-month pilot tests a nurse-led, app-based intervention to improve diabetes self-management for Medicaid patients. It includes MyChart messaging to give education, phone help on problem-solving with clinicians, and using a…
- Trial name
- virtual care (NCT06814184)
- Testing
- app-based nurse-led virtual diabetes care
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Rutgers, The State University of New Jersey
Type 2 Diabetes Mellitus
Efficacy and Safety of Mitiglinide vs Acarbose in Patients With Type 2 Diabetes Mellitus
Mitiglinide, a benzylsuccinic acid derivative, exerts selective action on the ATP-dependent K (KATP) channel of pancreatic β-cells and reportedly possesses a stronger affinity to the channel compared with other insulinotropic…
- Trial name
- Match-101 (NCT02143765)
- Testing
- Mitiglinide, Acarbose
- Where
- 6 sites in China
- Volunteers
- 248 people
- Sponsor
- Zhongda Hospital
Diabetes, Diabetes Mellitus, Type 1
Evaluation of Levemir® for the Treatment of Type 1 and 2 Diabetes
This study is conducted in Europe. The aim of this observational study is to evaluate the incidence of serious adverse drug reactions while using Levemir® under normal clinical practice conditions.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- PREDICTIVE™ (NCT00655044)
- Testing
- insulin detemir
- Where
- Russia
- Volunteers
- 3,637 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2
Emulation of the SUSTAIN6 Diabetes Trial Using Healthcare Claims
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials.
- Trial name
- NCT06659744
- Testing
- New use of semaglutide injection, New initiation of sitagliptin
- Where
- United States
- Volunteers
- 158,310 people
- Sponsor
- Brigham and Women's Hospital
Type 2 Diabetes
Characterization of the Variability Of Insulin Secretory Parameters in the Meal Tolerance and the Maximal Stimulation Tests of Subjects With Prediabetes
A multi-year clinical study to improve tools for measuring the function of insulin-producing beta cells in people with type 2 diabetes mellitus.
- Trial name
- NCT01663207
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Foundation for the National Institutes of Health
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
User Experience With DuraTouch® in Patients With Type 1 or Type 2 Diabetes
This study looks at overall impact of the use of DuraTouch® in terms of ease, convenience to use and satisfaction in participants with either type 1 or type 2 diabetes.The study will last for about 12 weeks.
- Trial name
- NCT07052292
- Testing
- DuraTouch®
- Where
- 11 sites in Poland
- Volunteers
- 128 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes
TriMaster: Study of a DPP4 Inhibitor, SGLT2 Inhibitor and Thiazolidinedione as Third Line Therapy in Patients With Type 2 Diabetes.
The aim of this project is to identify subgroups of patients with type 2 diabetes that respond well or poorly to particular drugs based on particular clinical characteristics such as their weight or kidney function, to enable…
- Trial name
- TriMaster (NCT02653209)
- Testing
- Sitagliptin - DPP4i, Canagliflozin - SGLT2i, Pioglitazone - TZD
- Where
- United Kingdom
- Volunteers
- 525 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Obesity, Diabetes Type 2
Pharmacogenetics of Response to GLP1R Agonists
Overweight/obese otherwise healthy volunteers will be recruited from the Old Order Amish population in Lancaster County, PA. Lancaster County, PA.
- Trial name
- PORT (NCT05071898)
- Testing
- Semaglutide Pen Injector [Ozempic]
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Heart Failure With Preserved Ejection Fraction, Type 2 Diabetes
Manganese-enhanced Magnetic Resonance Imaging (MEMRI) in Heart Failure With Preserved Ejection Fraction
Heart failure with preserved ejection fraction (HFpEF) is a condition in which the heart cannot fill with blood effectively. As a result, people with HFpEF suffer fatigue, breathlessness, and develop swollen limbs.
- Trial name
- MEMRI in HFpEF (NCT06652763)
- Testing
- Minnesota Living with Heart Failure Questionnaire, Echocardiogram, Six-minute walk test
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Type 2 Diabetes, Cardiovascular Risk
Canagliflozin and Myocardial Fibrosis
Recently, large clinical intervention studies have demonstrated the cardiovascular protective effects on of sodium-glucose cotransporter 2 inhibitors (SGLT2i) such as empagliflozin, dapagliflozin, and canagliflozin in reduction…
- Trial name
- CANA-DIA-FIB (NCT05367063)
- Testing
- Canagliflozin 100mg or Sitagliptin 100mg
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Shanghai Zhongshan Hospital
Type 2 Diabetes
Efficacy, Usability Study of the GlucoTab System for Glycaemic Management in Type 2 Diabetic Patients at General Wards
Objective: To investigate the performance (safety) of the GlucoTab system for glycaemic management in non-critically ill patients with type 2 diabetes at general wards.
- Trial name
- NCT01932775
- Testing
- GlucoTab System
- Where
- Austria
- Volunteers
- 99 people
- Sponsor
- Medical University of Graz
Type 2 Diabetes Mellitus
Insulin Effects on Metabolism and Cardiovascular Function in Type 2 Diabetes
Compared to human insulins analogue insulins offer the option of optimizing metabolism also in type 2 diabetes. Especially, fast acting insulin analogues lower postprandial glucose levels more effectively than human regular…
- Trial name
- NCT00747409
- Testing
- insulin aspart and detemir (NovoRapid, Levemir), human regular insulin and NPH insulin (Actrapid, Protaphne)
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Munich Municipal Hospital
Type 2 Diabetes, Hypertension
Individually Tailored Treatment of Type 2 Diabetes
The prevalence of Type 2 diabetes (T2D) is rising rapidly worldwide. In Denmark approximately 8% of adults have T2D and more than 25.000 are diagnosed each year. This has vast consequences for society and the patient.
- Trial name
- ITT (NCT02015130)
- Testing
- Individual treatment
- Where
- 4 sites in Denmark
- Volunteers
- 2,246 people
- Sponsor
- Odense University Hospital
Diabetes Mellitus
Safety and Efficacy of BGP-15 in Patients With Type 2 Diabetes Mellitus
This is a safety and dose finding efficacy study to evaluate the effects of BGP-15 over the dose range of 100 mg/day to 400 mg/day.
- Trial name
- NCT01069965
- Testing
- BGP-15 100 mg QD, BGP-15 100 mg BID, BGP-15 200 mg QD
- Where
- 30 sites in United States, Germany and 1 more
- Volunteers
- 196 people
- Sponsor
- N-Gene Research Laboratories, Inc.
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Effectiveness and Safety Study of the Abbott Sensor Based Glucose Monitoring Systems
The purpose of the study is to evaluate the safety and effectiveness of the Abbott Sensor Based Glucose Monitoring System Personal (System-P) and Abbott Sensor Based Glucose Monitoring System Professional (System-Pro) when used…
- Trial name
- NCT02283411
- Testing
- Abbott Sensor Based Glucose Monitoring System
- Where
- 6 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Abbott Diabetes Care
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