Clinical trials: Diabetes Mellitus Type II,
Type 2 Diabetes
Well-child Visit Video Project
The purpose of this study is to determine if incorporating videos on the importance of minimizing infant sugar-containing beverage (SCB) consumption into well-child visit protocols increases parents' SCB-related knowledge and…
- Trial name
- NCT05011292
- Testing
- Educational Video about SCB, Survey on child feeding and related knowledge and practices, Educational Video other than SCB
- Where
- United States
- Volunteers
- 388 people
- Sponsor
- Emory University
Obesity, Overweight
A Study of Macupatide (LY3532226) in Participants With Obesity or Overweight Without Type 2 Diabetes
The main purpose of this study is to assess how well macupatide, when dosed alone and in combination with eloralintide, is tolerated and what side effects may occur in participants with obesity or overweight without Type 2…
- Trial name
- NCT07765511
- Testing
- Macupatide, Eloralintide
- Where
- 3 sites in Japan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Low-GI Dietary Education, ADA Dietary Education
Diabetic Educational Eating Plan
By improving glycemic control, many of the devastating complications of diabetes are to a large extent preventable. The use of a low GI (glycemic index) diet to improve glycemic control is relatively new and untested.
- Trial name
- DEEP (NCT00473811)
- Testing
- Low GI, ADA diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Massachusetts, Worcester
Type 2 Diabetes Mellitus
To Evaluate the Efficacy and Safety of JT-003 add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase III Study to Evaluate the Efficacy and Safety of JT-003 Add-on in Patients with Type 2 Diabetes Mellitus Inadequately Controlled with Metformin and Dapagliflozin
- Trial name
- NCT05296044
- Testing
- JT-003
- Where
- South Korea
- Volunteers
- 245 people
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Type 2 Diabetes
The Evaluation of Laser Lancing Devices in Adult Type 2 Diabetes Patients
Self monitoring of blood glucose level is crucial in diabetes management, but currently available methods, lancet, have shown low compliance of self monitoring of blood glucose because of pain, keratinization of finger tip…
- Trial name
- NCT05251506
- Testing
- laser lancing device or lancet for blood glucose level measurement
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Korea University Guro Hospital
Type 2 Diabetes, Patient Engagement
The Effect of The Personalized Patient Engagement Plan on Diabetes Management
This study evaluates the effect of Personalized Patient Engagement Plan on diabetes management in patients with at least six months of Type-2 Diabetes.
- Conditions
- Type 2 Diabetes, Patient Engagement, Self Efficacy, Adherence, Patient
- Trial name
- NCT04256304
- Testing
- PHEinAction-Personalized Patient Engagement Plan
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Hacettepe University
Type 2 Diabetes Mellitus
Study on Liver Fat Content and Visceral Fat Mass in Overweight and Obese Type 2 Diabetes Patients After Treatment With Basal Insulin
Primary objective: To compare the change in liver fat content and visceral fat mass (cm2) assessed by MRS (Magnetic Resonance Spectroscopy) and MRI (Magnetic Resonance Image), after 26 weeks of treatment with insulin detemir once…
- Trial name
- NCT01310452
- Testing
- insulin detemir, neutral protamine insulin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fudan University
Diabetes Mellitus Type 2
A Study in Type 2 Diabetes Patients Who Are Taking Moderate Dose Insulin, Looking at the Effects of the Medication Luseogliflozin on Risk of Ketoacidosis and Insulin Resistance.
The goal of this clinical trial is to learn if the drug Luseogliflozin works to treat people with diabetes who are taking moderate dose insulin treatment. It will also learn about the safety of the drug Luseogliflozin.
- Trial name
- LUSIRES (NCT07876258)
- Testing
- Luseogliflozin
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- Aimi Fadilah Mohamad
New-onset Type 2 Diabetes
Efficacy and Safety of Henagliflozin Proline and Metformin Hydrochloride Extended-release Tablets (Ⅰ) Versus Metformin Tablets in Patients With New-onset Type 2 Diabetes: a Multicenter, Randomized Controlled Study
This multicenter, randomized controlled trial aims to evaluate the efficacy and safety of Henagliflozin-Metformin Sustained-Release Tablets (I) versus Metformin Tablets in newly diagnosed type 2 diabetes mellitus (T2DM).
- Trial name
- NCT06888050
- Testing
- henagliflozin proline and metformin hydrochloride extended-release tablets (Ⅰ), Metformin
- Where
- China
- Volunteers
- 268 people
- Sponsor
- Zhejiang Provincial People's Hospital
Type 2 Diabetes
Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Diet and Exercise Alone（UNIGUIDE-1）
This multicenter, randomized, double-Blind, parallel-group, placebo-controlled phase III trial is to evaluate the efficacy and safety of UBT251 Injection in patients with Type 2 Diabetes Mellitus with inadequate glycemic control…
- Trial name
- UNIGUIDE-1 (NCT07659574)
- Testing
- UBT251 Injection 2.0 mg, UBT251 Injection 4.0 mg, UBT251 Injection 6.0 mg
- Where
- China
- Volunteers
- 360 people
- Sponsor
- The United Bio-Technology (Hengqin) Co., Ltd.
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Safety and Efficacy of Technosphere® Insulin Inhalation Powder (TI Inhalation Powder)When an Optimal Dose is Taken With Varied Carbohydrate Intake
The purpose of this study is to determine if, once a favorable dose of TI Inhalation Powder is established for either a type 1 or 2 patient, based on a average diabetic meal, the patient's favorable dose can be used safely…
- Trial name
- NCT00747006
- Testing
- TI Inhalation Powder and Humalog (Amendment 1), TI Inhalation Powder (original protocol)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Mannkind Corporation
Cognitive Function Abnormal, Diabetes Mellitus, Type 2
Adaptation of a Cognitive Training Intervention for Diabetes Self-Management
The aims of this project are: (1) to refine an existing cognitive rehabilitation intervention and tailor it for persons with T2DM by using current literature and interview data from 10 participants with T2DM and (2) to conduct a…
- Trial name
- NCT03221452
- Testing
- Memory, Attention, and Problem Solving Skills for Diabetes
- Volunteers
- 29 people
- Sponsor
- University of Texas at Austin
Insulin Resistance
Does a Low-Fat Vegetarian Diet Improve Insulin Resistance in Individuals With Type 2 Diabetes?
The aim of the study is to evaluate the effect of experimental (vegetarian) diet compared to conventional diet with similar caloric restriction on insulin resistance, body weight and body composition in type 2 diabetic patients…
- Trial name
- NCT00883038
- Testing
- diabetic diet following the DNSG guidelines, low-fat vegetarian diet
- Where
- Czechia
- Volunteers
- 70 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Diabetes Mellitus, Type 2
Progressive Relaxation Exercise on Sleep Quality in Patients With Type 2 Diabetes
The purpose of this study is to evaluate the effect of progressive relief exercise on sleep quality in patients with type 2 diabetes.
- Trial name
- NCT05956743
- Testing
- progressive relaxation exercise sessions
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Mersin University
Diabetes
Study of Ro 205-2349 in Patients With Type 2 Diabetes Mellitus
The objective of the study is to determine the dose(s) of Ro 205-2349 which, when compared to placebo, are efficacious, safe and tolerable in improving glycemic control in patients with type 2 diabetes.
- Trial name
- NCT00057317
- Testing
- Ro 205-2349
- Where
- 117 sites in United States, Bulgaria and 9 more
- Sponsor
- Hoffmann-La Roche
Type 2 Diabetic Patients, Erectile Dysfunction
Prevalence and Risk Factors of Erectile Dysfunction in Type 2 Diabetic Patients
The investigators evaluated 250 male, type 2 diabetic patients, aged 18-80 years. They will undergo IIEF (International Index of Erectile Function), SAS of Zung (self-rating anxiety state)and SDS of Zung (self-rating depression…
- Trial name
- NCT01049750
- Testing
- type 2 diabetic patients
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- University of Pavia
Type 2 Diabetes
Beta-Cell Function After Near-Normalisation of Blood Glucose
The incretin effect is attenuated in patients with type 2 diabetes mellitus partly due to impaired potentiation of beta-cell responsiveness to glucose by glucose dependent insulinotropic polypeptide and glucagon-like peptide-1…
- Trial name
- NCT00612950
- Testing
- glucagon-like peptide-1,, glucose dependent insulinotropic polypeptide, Saline
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Type 2 Diabetes Mellitus
A Study to Evaluate Safety and Efficacy of PHX1149T in Subjects With Type 2 Diabetes Mellitus
This study is to test the efficacy and safety of PHX1149T in combination with metformin, a glitazone, or metformin and a glitazone in subjects with Type 2 diabetes for 12 weeks.
- Trial name
- NCT00482950
- Testing
- PHX1149T
- Where
- 26 sites in United States, Argentina and 3 more
- Volunteers
- 400 people
- Sponsor
- Phenomix
Diabetes Mellitus, Type 2
MARLINA - T2D : Efficacy, Safety & Modification of Albuminuria in Type 2 Diabetes Subjects With Renal Disease With LINAgliptin
Evaluate linagliptin in terms of glycemic control as defined by HbA1c after 24 weeks of treatment and in terms of renal efficacy as defined by changes in albuminuria (UACR) after 24 weeks of treatment.
- Trial name
- NCT01792518
- Testing
- Linagliptin 5mg
- Where
- 74 sites in United States, Canada and 10 more
- Volunteers
- 360 people
- Sponsor
- Boehringer Ingelheim
Type 2 Diabetes, Insulin Resistance
Effect of Low-Glycemic Index Mediterranean Diet on AGEs
Advanced glycation end products (AGE) result from a chemical reaction between the carbonyl group of reducing sugar and the nucleophilic NH2 of a free amino acid or a protein; lysine and arginine being the main reactive amino…
- Conditions
- Type 2 Diabetes, Insulin Resistance, Obesity, Cardiovascular Disease
- Trial name
- Nutri_AGEs (NCT02353416)
- Testing
- Low Glycemic Index Mediterranean Diet, INRAM Guidelines' diet
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
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