Clinical trials: Diabetes Prevention
Obesity
Adapted Physical Activity Study
An uncontrolled, non-randomized, open-plan, multi-centre study of treatment and therapeutic education in endocrinology-diabetes-Nutrition that seeks to assess the interest of an adapted physical activity educator for the…
- Trial name
- APA (NCT03337412)
- Testing
- Adapted physical activity
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Diabetes
Therapeutic Stockings to Prevent Foot Ulcers
1. To evaluate the efficacy of a therapeutic stockings (Protective Foot Care stockings, PFC) in reducing the incidence of diabetic foot pathology among high-risk patients. 2.
- Trial name
- NCT01221194
- Testing
- Standard therapy, PFC Stockings
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 381 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetes, Heart Disease
Family Health History in Diverse Care Settings (FHH)
The outcome of this research will be a demonstration that family health history (FHH) risk data can be used efficiently to deliver more effective healthcare in geographically and ethnically diverse clinical care environments.
- Conditions
- Diabetes, Heart Disease, Cancer
- Trial name
- FHH (NCT01956773)
- Testing
- MeTree
- Where
- 5 sites in United States
- Volunteers
- 2,620 people, healthy volunteers welcome
- Sponsor
- Duke University
Metabolic-dysfunction Associated Liver Disease (MASLD)
Testing a Multilevel, Culturally Appropriate Lifestyle Intervention For Hispanic Patients With Metabolic Dysfunction-associated Steatotic Liver Disease
The purpose of this study is to understand if a behavioral lifestyle intervention called the Healthy Liver/Hígado Sano program can help Hispanic/Latino patients with metabolic dysfunction associated steatotic liver disease…
- Trial name
- NCT07199491
- Testing
- Healthy Liver/Hígado Sano program, Usual Care
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- The University of Texas Health Science Center, Houston
Prediabetic State, Metabolic Syndrome X
Culturally-adapted Diabetes Prevention Lifestyle Intervention for Latinos (E-LITE Latinos)
The purpose of the study is to develop a culturally adapted intervention (CAI) program to improve weight and physical activity in overweight or obese adult Latinos at high risk for developing type 2 diabetes and/or cardiovascular…
- Conditions
- Prediabetic State, Metabolic Syndrome X, Insulin Resistance
- Trial name
- NCT02459691
- Testing
- Vida Sana, Usual Care Only
- Volunteers
- 191 people
- Sponsor
- Palo Alto Medical Foundation
Diabetes
A Randomized Trial of an Intensive Education Intervention Using a Network of Involved Diabetic Patients (Peer Educators) to Improve Glycemic Control of Type 2 Diabetic Patients
The project will test the implementation of a specific methodology for education of type 2 diabetic patients that will be set up using patients involved (peer educators) and 3 guides developed specifically for the therapeutic…
- Trial name
- NCT01485913
- Testing
- intensive education intervention using a network of involved diabetic patients (peer educators)
- Where
- Mali
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Sante Diabete Mali
Prediabetes
Prevention of Type 2 Diabetes With Vitamin D Supplementation
PREVENT-WIN study has three components. The work plan will have the following S\&T components. Component 1: Cross-sectional Study Cross-sectional study will be of 1.5 years where 400 women from rural will be screened randomly for…
- Trial name
- PREVENT-WIN (NCT02513888)
- Testing
- vitamin D + diet and lifestyle
- Where
- India
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Diabetes Mellitus
Effects of Exercise Behavior Modification on Plasma Adiponectin and Insulin Resistance in High Risk Subjects of Diabetes
Investigators hypothesized home-based exercise intervention was beneficial to those who have had diabetic risk factor for type 2 diabetes mellitus
- Trial name
- NCT01136096
- Testing
- Physical activity promoting intervention, General instruction and education
- Where
- Taiwan
- Volunteers
- 216 people
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus
ASCEND: A Study of Cardiovascular Events iN Diabetes
The purpose of this study is to determine whether 100mg daily aspirin versus placebo and/or supplementation with 1 gram daily omega-3 fatty acids or placebo prevents "serious vascular events" (i.e.
- Trial name
- NCT00135226
- Testing
- Aspirin, Omega-3 Ethyl Esters
- Where
- United Kingdom
- Volunteers
- 15,480 people
- Sponsor
- University of Oxford
Prediabetic State, Obesity
Presessions for the National Diabetes Prevention Program
The National Diabetes Prevention Program (NDPP) is a widely available, evidence-based intervention that promotes weight loss to prevent type 2 diabetes; however, participant attendance is problematic and leads to suboptimal…
- Conditions
- Prediabetic State, Obesity, Gestational Diabetes
- Trial name
- NCT04022499
- Testing
- Presessions, National Diabetes Prevention Program
- Where
- United States
- Volunteers
- 483 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Diabetes, Type I
Prevention of Clinical Onset of Type 1 Diabetes in High Risk First Degree Relatives
Prophylactic administration of metabolically active insulin can prevent or delay clinical onset of diabetes in a high risk group of nondiabetic siblings as defined by positivity for autoantibodies against IA-2 (IA-2-A).
- Trial name
- NCT00654121
- Testing
- Actrapid HM
- Where
- 3 sites in Belgium
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Diabetes Mellitus, Type 1, Hypoglycemia
T1 Diabetes Hypoglycemia Prevention Pilot
A single center pilot study assessing the Vigilant Diabetes Management System for the prevention of recurrent mild to moderate hypoglycemia in type I diabetes patients.
- Trial name
- NCT02682940
- Testing
- Vigilant Diabetes Management Application
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- InSpark Technologies, Inc.
Type 2 Diabetes
Beneficial Effects of Quinoa (Chenopodium Quinoa Willd) in the Prevention of Type 2 Diabetes Mellitus
Quinoa is a pseudo-cereal and has potential health benefits and exceptional nutritional value. It is a food rich in proteins of high biological value, in unsaturated fats and fiber, it is also a grain low in carbohydrates and…
- Trial name
- NCT04529317
- Testing
- Quinoa and quinoa-based food
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Prediabetic State, Insulin Resistance
United for Health: Type 2 Diabetes Prevention in Latino Teens
This study pilots the feasibility and acceptability of a family-based lifestyle intervention for decreasing diabetes risk called "Salud sin Barreras" (meaning, "Health without Barriers") delivered in the community to Latino teens…
- Conditions
- Prediabetic State, Insulin Resistance, Type2 Diabetes, Stress
- Trial name
- UNITED (NCT03527641)
- Testing
- CookingMatters, Parent Education, Physical Activity
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Colorado State University
Diabetes Prevention, Obesity Prevention
Fluid Dairy Products Consumed Before and Within a Pizza Meal on Glycemic Response, Food Intake and Satiety in Children
The purpose of this study is to examine the effects of fluid dairy products on blood glucose and insulin, satiety and energy intake in normal weight and overweight/obese children in the age range of 9-14 y.
- Trial name
- NCT02147496
- Testing
- Dietary Intervention
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 1 Diabetes
Closed-Loop Glucagon Administration For Hypoglycemia Treatment
This study will test the hypothesis that a wearable automated bionic pancreas system that automatically delivers glucagon only can prevent or treat hypoglycemia vs. usual care for people with type 1 diabetes > 21 years old.
- Trial name
- NCT02181127
- Testing
- Glucagon-only Bionic Pancreas
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Infant Overweight, Infant Obesity
Project Sueño: Sleep & Understanding Early Nutrition in Obesity
The purpose of the study is to understand how mothers think and feel about feeding their babies and putting them to sleep, understand more about programs that can support mothers taking care of babies, and how professionals can…
- Conditions
- Infant Overweight, Infant Obesity, Infant Overnutrition, Infant Development
- Trial name
- NCT06117631
- Testing
- Centering Parenting, Bright by Text
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Prediabetes
Effects of Berberine Hydrochloride and Bifidobacterium in Prediabetes Prevention and Treatment
The aim of this study is to assess the beneficial effects of Bifidobacterium and Berberine Hydrochloride on lowering glucose and delaying progress to diabetes in patients with prediabetes and to detect the potential mechanism.
- Trial name
- NCT02082756
- Testing
- Bifidobacterium viable pharmaceutics, Berberine Hydrochloride
- Where
- 4 sites in China
- Sponsor
- Xijing Hospital
Foot Ulcer, Diabetic
Pressure Alternating Shoes
The project is designed to develop and test Pressure Alternating Shoes (PAS), which will periodically off-load certain regions of the foot in order to prevent foot ulcers.
- Trial name
- PAS (NCT06026813)
- Testing
- test pressure alternating shoes
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pre-diabetes
More Health Less Diabetes
The "More Health, Less Diabetes" project is a hybrid randomized controlled trial to prevent type 2 diabetes in individuals at risk through structured exercise and lifestyle education.
- Trial name
- MHLD (NCT07079722)
- Testing
- Exercise
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana