Clinical trials: Diabetes Risk
Cardiovascular Risk Factor, Cardiovascular Diseases
Effects of Breaking up Prolonged Sitting on Postprandial Cardiometabolic Disease Risk Markers in South Asian Adults
The purpose of this study is to examine whether breaking up prolonged sitting with short regular bouts of walking can reduce blood sugar and cholesterol levels after eating, which are risk markers for Type 2 diabetes and heart…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Diabetes, Physical Activity
- Trial name
- NCT03898206
- Testing
- Breaking up sitting with walking breaks (INT-SIT), Prolonged sitting (SIT)
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Bedfordshire
Asthma
Effect of Inhaled Steroids on Glucose Regulation in Asthma Patients
Inhaled steroid has been the cornerstone in the treatment of asthma, which carries a huge patient population worldwide including Hong Kong. In general, the safety of long-term use of inhaled steroid has been well documented.
- Trial name
- NCT00959348
- Where
- 4 sites in Hong Kong
- Volunteers
- 1,394 people
- Sponsor
- The University of Hong Kong
Cardiovascular Diseases, Hypercholesterolemia
Vascular Lifestyle-Intervention and Screening in Pharmacy
The overall goal of the present project is to contribute to new knowledge about the effect of a low threshold population screening system for cardiovascular risk factors in Norway.
- Conditions
- Cardiovascular Diseases, Hypercholesterolemia, Dyslipidemia, Hypertensive Disease
- Trial name
- VISA (NCT02223793)
- Testing
- Information on high risk factor levels and lifestyle advice, No information on high risk factor levels but lifestyle advice, No information on high risk factor levels, nor lifestyle advice
- Where
- Norway
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Abdominal Obesity, Metabolic Syndrome
Growth Hormone Treatment in Men With High Risk of Developing Type 2 Diabetes Mellitus
The overall aim of this study is to investigate the effects of GH treatment in men with the Metabolic Syndrome and a high risk of developing type 2 DM.
- Conditions
- Abdominal Obesity, Metabolic Syndrome, Obesity
- Trial name
- GHDM (NCT00781547)
- Testing
- recombinant human growth hormone
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Göteborg University
Diabetes Mellitus, Type 2
Lifestyle Intervention For Effective Diabetes Management
Chronic disease management programs are shown to reduce mortality, recurrent hospitalizations, and improve indirect societal costs among specific subgroups of the population.
- Trial name
- LIFE-DM (NCT00813930)
- Testing
- INTERxVENT lifestyle modification program
- Where
- 3 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Unity Health Toronto
Patients Undergoing Coronary Angiography
Study of the Effect of Diabetes on the Incidence and the Extent of Coronary Artery Disease
In the present study the investigators will measure the extent of coronary artery disease via coronary angiography and the correlating risk factors.
- Trial name
- NCT01585948
- Where
- Greece
- Volunteers
- 1,104 people
- Sponsor
- University of Ioannina
Child Development
The Effect of Early-life Risk Factors on the Etiology of Diabetes in Children: a Birth Cohort
In recent years, with the rising prevalence of obesity among children, the incidence of type 2 diabetes in children and adolescents has continued to be increased.
- Trial name
- NCT04313998
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sijia Gu
Cardiovascular Diseases, Diabetes Mellitus
Improving Medication Safety and CVD Risk Factor Control in Kidney Transplant Recipients
There is a lack of data analyzing the influence of Cardio-vascular Diseases (CVD) risk factor control on graft survival disparities in Black transplant recipients.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Medication Adherence
- Trial name
- NCT02763943
- Testing
- Pharmacist-led, technology enabled education intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medical University of South Carolina
Fetal Macrosomatia, Lipid Metabolism Disorders
Influence of TyG Index and TG/HDL-C Ratio on Fetal Macrosomia
Metabolic disorders that can occur during pregnancy, in particular disorders of lipid metabolism and insulin resistance, can have a detrimental effect on pregnancy and the fetus.
- Conditions
- Fetal Macrosomatia, Lipid Metabolism Disorders, Hyperlipidemias
- Trial name
- NCT06463990
- Testing
- TyG index
- Where
- Turkey (Türkiye)
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Cardiovascular Diseases, Heart Diseases
Reducing Total Cardiovascular Risk in an Urban Community
PLEASE NOTE: THIS STUDY IS ONLY ENROLLING PATIENTS CURRENTLY BEING TREATED AT BELAIR-EDISON FAMILY HEALTH CENTER. The purpose of this study is to compare the clinical effectiveness and cost effectiveness of two cardiovascular…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Diabetes Mellitus
- Trial name
- COACH (NCT00241904)
- Testing
- Lifestyle Changes, Antiplatelet Agents, Beta Blocker
- Where
- United States
- Volunteers
- 525 people
- Sponsor
- Johns Hopkins University
Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Risk-informed Shared-decision Making Engagement Strategy for Patients With Prediabetes
The goal of this clinical trial is to learn if knowing risk for diabetes can help adult patients with prediabetes take steps to get care and prevent diabetes.
- Trial name
- RISE (NCT07553325)
- Testing
- Risk Informed Shared Decision-Making Strategy (RISE), Low Touch Messaging Strategy (LTM)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Johns Hopkins University
Atherosclerosis, Cardiovascular Diseases
Risk Factors for Atherogenesis in Type 1 Diabetes
To determine risk factors for atherogenesis in Type 1 diabetes.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Diabetes Mellitus, Insulin-dependent, Heart Diseases
- Trial name
- NCT00035750
- Sponsor
- University of Wisconsin, Madison
Diabetes Mellitus, Type 2
Time Efficient Exercise in Type 2 Diabetes
Exercise is considered a cornerstone in the prevention and treatment of type 2 diabetes, but few patients exercise according to guidelines.
- Trial name
- NCT02340260
- Testing
- High intensity interval training, Sprint interval training
- Where
- Norway
- Volunteers
- 21 people
- Sponsor
- Norwegian University of Science and Technology
Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Pharmacists' Delivery of Education to Prevent Diabetes in the New Orleans Hospitality Industry
This is a one-year pilot study focused on prediabetes among hospitality workers in New Orleans, Louisiana. The project will assess prediabetes rates among the target population, evaluate the impact of pharmacist led lifestyle…
- Conditions
- Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetic State &Amp; High Risk Individuals on the Basis of Diabetes Risk Score
- Trial name
- NCT07451314
- Testing
- Linkage to Care, Educational, Healthy Lifestyle Tools
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Prediabetes
Nested Pilot Study Comparing Two Treatments to Reduce Type 2 Diabetes Risk in At-Risk Delawareans
This nested pilot Randomized Clinical Trial will determine whether the Diabetes Prevention Program (DPP) enhanced with evidence-based sleep health and time restricted eating interventions ("DPP++") is more effective than the DPP…
- Trial name
- NCT07450118
- Testing
- National Diabetes Prevention Program (DPP), Sleep Health Digital Application, Time-Restricted Eating (TRE)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Delaware
Sleep, Diabetes
Individual Differences in Diabetes Risk: Role of Sleep Disturbances
The hypothesis for this study is that some individuals may be at much higher risk to develop type 2 diabetes and that the individual diabetes risk will be predicted by the individual level of slow wave sleep activity (SWA).
- Trial name
- NCT00989976
- Testing
- normal sleep times, bedtime restriction
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Cardiovascular Health, Self-management
MECA Clinical Intervention ( MECA Health360x)
The purpose of this research is to test whether a technology application(Health360x) that lets participants set goals for better health and track health can help participants reduce their heart disease risk.
- Trial name
- MECAH360x (NCT04791618)
- Testing
- Health360x plus health coach, Health360x only (High tech)
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Type 2 Diabetes
A Comprehensive Longitudinal Cohort Study in Type 2 Diabetes With High Risk of Cardiovascular Diseases in China
In 2010, the sponsor conducted an observational study, entitled as "Nationwide Assessment of Cardiovascular Risk Factors: Blood Pressure, Blood Lipid, and Blood Glucose, in Chinese Patients with Type 2 Diabetes - 3B Study " which…
- Trial name
- CCMR-3B Ext (NCT01307410)
- Volunteers
- 5,000 people
- Sponsor
- China Cardiometabolic Registries
Diabetes Mellitus Type 2
Medium-term Effects of a Polyphenol-rich Beverage Based on Red Grape Pomace Extract on Non-alcoholic Fatty Liver Disease, Cardiometabolic Risk Profile and Gut Microbiota in Subjects with Type 2 Diabetes
Nonalcoholic fatty liver disease (NAFLD) is a liver disease characterized by an abnormal accumulation of fat not due to alcohol or drug consumption that can evolve into steatohepatitis (NASH), fibrosis and cirrhosis.
- Trial name
- PoLiFat (NCT06895018)
- Testing
- Supplementation with Polyphenol Rich Drink
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
Type 2 Diabetes, Cardiovascular Diseases
Pistachios Blood Sugar Control, Heart and Gut Health
A two-period randomized crossover study will be conducted to evaluate the effect of nighttime pistachio consumption (i.e., after dinner and before sleep) on fasting blood sugar levels, longer-term blood sugar control, and risk…
- Trial name
- NCT04056208
- Testing
- Pistachio, Usual care
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Penn State University
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