Clinical trials: Diabetes Treatment (Pilot Study)
Diabetic Neuropathies, Painful, Diabetic Foot
Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain
The purpose of this research is to assess whether the use of a topical cream with an active ingredient can reduce the amount of foot pain experienced in participants who have been diagnosed with Diabetic Peripheral Neuropathy…
- Conditions
- Diabetic Neuropathies, Painful, Diabetic Foot, Diabetic Peripheral Neuropathy
- Trial name
- NCT07260656
- Testing
- Capsaicin Palmitate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Carilion Clinic
Type 1 Diabetes, Monogenic Diabetes
Oral Hypoglycemic Therapy for Monogenic Variant Carriers of the Joslin Medalist Study
The purpose of this study is to evaluate the efficacy of adding oral hypoglycemic agents (OHA) to existing insulin treatment in monogenic variant carriers of the Joslin 50-Year Medalist Study ("Medalists"), who are characterized…
- Trial name
- NCT04409795
- Testing
- Metformin Extended Release Oral Tablet, Sitagliptin
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Joslin Diabetes Center
Endometrial Cancer
A Study of a Weight Loss Intervention in People With Endometrial Cancer
The researchers are doing this study is to find out whether tirzepatide and semaglutide are practical (feasible) for weight management and blood sugar control for endometrial cancer patients undergoing chemotherapy.
- Trial name
- NCT06751589
- Testing
- Tirzepatide
- Where
- 7 sites in United States
- Volunteers
- 4 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Stage 3 Type 1 Diabetes
Autologous CD6-CAR Treg Cells for Patients With Stage 3 Type 1 Diabetes
Type 1 diabetes (T1D) is a persistent and gradually increasing genetic autoimmune disease requiring life-long management. The disease commonly impacts children. However, a quarter of cases are diagnosed in adults.
- Trial name
- NCT07395050
- Testing
- AutoCD6-CAR Treg cells
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- City of Hope Medical Center
Heart Failure, Diabetes Mellitus, Type 2
Insulin Treatment in Diabetic Older People With Heart Failure.
Cardiac failure (HF) and type 2 diabetes mellitus (T2DM) are two clinical conditions with a significant impact on public health worldwide.
- Trial name
- Insulin-HF (NCT03665350)
- Testing
- Insulin
- Where
- 3 sites in Italy
- Volunteers
- 10 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Type 2 Diabetes
Safety & Effectiveness of Duodenal Mucosal Resurfacing (DMR) Using the Revita™ System in Treatment of Type 2 Diabetes
The Revita™ System is being investigated to assess the ability to improve glycemic control in conjunction with diet and exercise in patients with Type 2 diabetes who are inadequately controlled with oral anti-diabetic…
- Trial name
- NCT03653091
- Testing
- Duodenal Mucosal Resurfacing (DMR)
- Where
- 6 sites in United States
- Volunteers
- 9 people
- Sponsor
- Fractyl Health Inc.
Type 2 Diabetes Treated With Insulin
Intensive Lifestyle Intervention in Patients With Insulin-treated Type 2 Diabetes: a Pilot Project
This study is a pilot study carried out to assess the feasibility, safety and effectiveness of an intensive lifestyle intervention, implemented virtually by a multidisciplinary team, in patients living with advanced…
- Trial name
- ILIAD (NCT04957173)
- Testing
- Lifestyle intervention
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Moderate Non-proliferative Diabetic Retinopathy
The Use of Alpha Lipoic Acid for the Treatment and Prevention of Diabetic Retinopathy
The purpose of this study is to evaluate the role of alpha lipoic acid in patients who have moderate non-proliferative diabetic retinopathy.
- Trial name
- ALA-TPD (NCT01880372)
- Testing
- Alpha Lipoic Acid
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Ferris State University
Diabetes Mellitus
Pilot Study of Glycemic Control in Diabetic Hemodialyzed Patients
The purpose of the study is to evaluate the effect of the basal-bolus detemir-aspart insulin regimen coupled with continuous glucose monitoring (CGM) on glycemic control in hemodialyzed patients with diabetes
- Trial name
- GlyCEDIA (NCT01828970)
- Testing
- Basal-bolus detemir-aspart insulin regimen
- Where
- 5 sites in France
- Volunteers
- 38 people
- Sponsor
- Centre Europeen d'Etude du Diabete
Asthma, Breast Neoplasms
Digital Tool Enhancing GPs' Information Management for Patients with Multimorbidity - a Pilot Study
The gp-multitool.de study is a cluster-randomized controlled trial that aims to enhance evidence-based and patient-centered care for patients with multimorbidity by assessing and providing information relevant for the primary…
- Conditions
- Asthma, Breast Neoplasms, Coronary Disease, Diabetes Mellitus, Type 1
- Trial name
- gp-multitool (NCT06061172)
- Testing
- gp-multitool.de
- Where
- Germany
- Volunteers
- 123 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Diabetic Macular Edema
Near-infrared Light (NIR) Therapy for Diabetic Macular Edema: A Pilot Study
Summary of Study Rationale Near-infrared light (NIR) via light-emitting diodes (LED) treatment promotes retinal healing and improve visual function following high intensity laser retinal injury by augmenting cellular energy…
- Trial name
- NIR (NCT00846092)
- Testing
- Warp 10 LED Device, Near-infrared light (NIR)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Medical College of Wisconsin
Diabetes Mellitus, Type 2, Vascular Diseases
Effect of Thiazolidinedione Treatment Vascular Risk Markers
The purpose of this study is to examine the effects of two diabetes medications, rosiglitazone and pioglitazone, on markers of vascular disease in subjects with type 2 diabetes.
- Trial name
- NCT00571506
- Testing
- Rosiglitazone, Pioglitazone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Arkansas
Dyslipidemias, Diabetes Mellitus, Type 2
GWMD1092 - GWP42003 : GWP42004 Together Plus Alone in Type II Diabetes
This 15-19 week study is being conducted by GW Pharma Ltd as a pilot study in order to determine the efficacy and safety of two cannabinoids: GWP42004 and GWP42003 alone, or in combination in patients with Type 2 diabetes.
- Trial name
- NCT01217112
- Testing
- GWP42003, GWP42004
- Where
- 5 sites in United Kingdom
- Volunteers
- 62 people
- Sponsor
- Jazz Pharmaceuticals
Type 2 Diabetes
Education and Exercise Program for Adults With Type 2 Diabetes
The purpose of this two phase study is to: 1) develop and 2) assess a program titled: Merging Yoga, Occupational Therapy and Nutrition Education (MY-OT-Ed) designed for low income adults with Type 2 Diabetes.
- Trial name
- NCT04164030
- Testing
- Education and Exercise Program for Adults with Type 2 Diabetes, Nutrition Education plus Occupational Therapy plus Yoga
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Colorado State University
Neuralgia, Neuralgia; Postherpetic
Evaluation of an Effectiveness and Safety of the Electroacupuncture in the Management of Intractable Neuropathic Pain
The investigators will evaluate the effectiveness and safety of acupuncture treatment in refractory neuropathic pain patients.
- Conditions
- Neuralgia, Neuralgia; Postherpetic, Diabetic Neuropathy, Painful, Failed Back Surgery Syndrome
- Trial name
- NCT03315598
- Testing
- Electroacupuncture
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Diabetic Retinopathy
Triamcinolone Acetonide Injections to Treat Diabetic Macular Edema
This study will evaluate which of the three following treatment options is better for diabetic macular edema: laser alone, steroid injection alone, or steroid injection followed by laser.
- Trial name
- NCT00231023
- Testing
- Peribulbar Triamcinolone Acetonide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Eye Institute (NEI)
Diabetes Mellitus, Type 2
A Study to Evaluate Eli Lilly's Insulin Dosing Algorithm to Control Glycemia in Insulin-treated Adults With Type 2 Diabetes
The objective of this study is to generate preliminary data in an inpatient setting to help optimize an insulin dosing logic (that decides how much to deliver insulin) for Eli Lilly's system.
- Trial name
- NCT05514080
- Testing
- Insulin closed-loop
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University
Hypogonadism, Diabetes
Testosterone for Men With Insulin Treated Type 2 Diabetes
The purpose of this study is to test the effect of testosterone treatment on glycaemic control, arterial stiffness and IMT in hypogonadal men with type 2 diabetes treated with insulin.
- Trial name
- NCT00349362
- Testing
- Testosterone, 0.9% saline
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Barnsley Hospital
Peripheral Neuropathy, Diabetes Mellitus
IVIg for Demyelination in Diabetes Mellitus
The purpose of this study is to determine whether intravenous immunoglobulin (IVIg) is an effective intervention for patients with diabetes, peripheral neuropathy, and demyelination on nerve conduction studies.
- Conditions
- Peripheral Neuropathy, Diabetes Mellitus, Chronic Inflammatory Demyelinating Polyneuropathy
- Trial name
- IDIDM (NCT02372149)
- Testing
- 10% intravenous immunoglobulin (IVIg), 0.9% sodium chloride
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Toronto
Diabetic Foot Ulcer
The Effects of High Energy Acoustic Shock Wave Therapy on Local Skin Perfusion and DFUs
This is an observational, single-arm, on-label study. This clinical study will be conducted at up to 2 sites with a total of 10 subjects per site.
- Trial name
- NCT03640988
- Testing
- dermaPACE
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- SANUWAVE, Inc.