Clinical trials: Diabetes in Pregnancy
Septic Shock
Discontinuation Order of Vasopressors in Septic Shock
The purpose of this study is to evaluate the incidence of hypotension based on the discontinuation order of norepinephrine and vasopressin in patients receiving concomitant norepinephrine and vasopressin infusions for the…
- Trial name
- DOVSS (NCT01493102)
- Testing
- Vasopressin, Norepinephrine
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Samsung Medical Center
Seizures, S-100b Protein
Biomarkers In Seizure To Predict Recurrence and Severe Outcomes
We study the hypothesis that combination of Proteine S100 beta and Copeptin within normal ranges can rule out seizure recurrences and severe outcome, and allow early discharge from the emergency department
- Conditions
- Seizures, S-100b Protein, Copeptin
- Trial name
- BISTRO (NCT01774500)
- Where
- 4 sites in France, United Kingdom
- Volunteers
- 300 people
- Sponsor
- Bistro Study Group
Chronic Kidney Disease, Type 2 Diabetes
A Study of RTA 402 in Chronic Kidney Disease (CKD) Patients With Type 2 Diabetes Mellitus
A Phase 2 study of RTA 402 in Chronic kidney disease (CKD) patients with type 2 diabetes mellitus.
- Trial name
- NCT01574365
- Testing
- RTA 402
- Where
- Japan
- Volunteers
- 53 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Type 1 Diabetes, Pregnancy in Diabetic
Telemedicine in Pregnant Women With Type 1 Diabetes Mellitus
Hypothesize that co-managing pregnant type 1 diabetics with telemedicine will have at least equivalent outcomes to those managed with standard care.
- Trial name
- NCT04278664
- Volunteers
- 5 people
- Sponsor
- Ana Braescu
Diabetes Mellitus in Pregnancy, Type 2 Diabetes Mellitus (T2DM)
RCT Glargine vs NPH for Treatment of DM in Pregnancy
We are asking you to take part in this research study because you are diagnosed with pregestational Type 2 Diabetes Mellitus or Gestational Diabetes Mellitus requiring insulin therapy in pregnancy.
- Conditions
- Diabetes Mellitus in Pregnancy, Type 2 Diabetes Mellitus (T2DM), Gestational Diabetes Mellitus, Class A2
- Trial name
- NCT06619301
- Testing
- Insulin glargine, insulin NPH
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Loyola University
Gestational Diabetes Mellitus in Pregnancy
Acute Metabolic Effects of Pre-meal Consumption of Whey in Women at Risk of Gestational Diabetes Mellitus
The main objective of our study is to investigate the metabolic effects of whey protein (whey protein isolate, WPI, (Lacprodan® ISO.Water.
- Trial name
- NCT04767880
- Testing
- Whey
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diabete Mellitus, Diabetic Nephropathy
Nephroprotective Effects of Fig (Ficus Carica L.) Leaf Supplementation
Diabetic nephropathy is the result of diabetes complications. Excessive blood glucose levels affect several organs which include liver, heart, and kidneys.The aim of this study is to use the nephroprotective and metabolic effects…
- Trial name
- NCT07718880
- Testing
- Control group, Intervention group
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Diabetic Kidney Disease, Type 1 Diabetes
Efficacy of Dapagliflozin in Early Diabetic Nephropathy in Type 1 Diabetes
Diabetic kidney disease (DKD) is a leading cause of chronic and end-stage kidney disease, affecting 25-40% of type 1 diabetes (T1D) patients and 5-40% of type 2 diabetes (T2D) patients.
- Trial name
- NCT06532682
- Testing
- dapagliflozin, ACE inhibitor
- Where
- China
- Volunteers
- 54 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Diabetes Mellitus, Diabetes, Gestational
Randomized Clinical Trial of Lifestyle Interventions to Prevent Diabetes in Women With Previous Gestational Diabetes
Randomized trial aiming to investigate the effectiveness of a lifestyle intervention program implemented within the first year after a pregnancy complicated by gestational diabetes (GDM), in delaying or preventing the development…
- Trial name
- LINDA-Brasil (NCT02327286)
- Testing
- Promote and support healthy behaviors
- Where
- 3 sites in Brazil
- Volunteers
- 473 people
- Sponsor
- Federal University of Rio Grande do Sul
Fetal Macrosomia, Abdominal Wall Mass
Fetal Front-abdominal Wall Thickness and Perinatal Outcome
Abnormal fetal development such as macrosomia can cause some complications on both fetus and mother.The measurement of fetal anterior abdominal wall thickness (FAWT) is an easy examination that it can be obtained during an…
- Conditions
- Fetal Macrosomia, Abdominal Wall Mass, Perinatal Problems
- Trial name
- NCT03232294
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
GDM
Chrono Nutrition (CN) Intervention Program in Gestational Diabetes Mellitus
Working hypothesis and aims: To asses Chrono Biological factors during the third trimester of gestational diabetes melittus (GDM) with birth weight and related complications.
- Trial name
- CN (NCT02916667)
- Testing
- dietary guidelines
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Gestational Diabetes, Other "Heavy-For-Dates" Infants
Pregnancy Outcomes and Maternal Insulin Sensitivity
The PROMIS study will focus on maternal insulin sensitivity thourghout pregnancy and postpartum in a moderate to high risk population (BMI ≥25 kg/m2) in developing adverse pregnancy outcomes.
- Conditions
- Gestational Diabetes, Other "Heavy-For-Dates" Infants, Small for Gestational Age Infant, Diabetes Mellitus, Type 2
- Trial name
- PROMIS (NCT04315545)
- Testing
- meal tolerance test
- Where
- 2 sites in Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Pregnancy, Thyroid Function Tests
Maternal Thyroid Function in Early Pregnancy and Their Relationship With Gestational Diabetes Mellitus
This study was conducted to analyze the role of TSH level and TPOAb status in early pregnancy and use this information in assessment of the risk of gestational diabetes mellitus at different weeks of gestation when the FT4 level…
- Conditions
- Pregnancy, Thyroid Function Tests, Gestational Diabetes Mellitus
- Trial name
- NCT02555332
- Testing
- 75g oral glucose tolerance test (OGTT)
- Volunteers
- 7,729 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Diabetic Nephropathy
An Extended Treatment Study of MT-3995 in Patients With Diabetic Nephropathy
This study aims to evaluate the safety and efficacy of MT-3995 administered over the longer term, following MT-3995-J05 study.
- Trial name
- NCT02676401
- Testing
- MT-3995 Low, MT-3995 Middle, MT-3995 High
- Where
- Japan
- Volunteers
- 241 people
- Sponsor
- Tanabe Pharma Corporation
Diabetic Kidney Disease (DKD)
Vascular Endothelial Growth Factor-B (VEGF-B) Blockade With the Monoclonal Antibody CSL346 in Subjects With Diabetic Kidney Disease
This phase 2a, double-blind, randomized, placebo-controlled study will assess the efficacy, safety, tolerability, and pharmacokinetics (PK), of repeat doses of CSL346 in subjects with diabetic kidney disease (DKD) and albuminuria…
- Trial name
- NCT04419467
- Testing
- CSL346
- Where
- 37 sites in United States, Australia and 4 more
- Volunteers
- 114 people
- Sponsor
- CSL Behring
Gestational Diabetes Mellitus
Lifestyle Intervention and Prevention of Gestational Diabetes Mellitus
The number of women with gestational diabetes mellitus (GDM) had been increasing. Maternal GDM has a great impact on both the health of the mothers and the offspring.
- Trial name
- NCT02368600
- Testing
- Lifestyle modification program
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Diabetes, Gestational, Insulin Resistance
Metformin in Gestational Diabetes Mellitus
Gestational diabetes (GDM) is a condition that manifests as high blood sugar levels (hyperglycemia) during pregnancy in previously healthy women.
- Trial name
- MetGDM (NCT00681460)
- Testing
- human recombined insulin, metformin
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- K. Marcinkowski University of Medical Sciences
Chronic Kidney Disease, Type 2 Diabetes Mellitus
A Study Using Surveys to Learn More About Treatment With Steroidal Mineralocorticoid Receptor Antagonists, How They Are Used, What Side Effects They Have, and How Satisfied People Who Receive Them Are in the US
This is an observational study in which patients with chronic kidney diseases (CKD), type 2 diabetes (T2D) or heart failure (HF) who are current or past users of sMRA therapies are studied.
- Conditions
- Chronic Kidney Disease, Type 2 Diabetes Mellitus, Heart Failure
- Trial name
- NCT05407662
- Testing
- sMRA therapies
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Bayer
Respiratory Disorder in Patient With Gestational Diabetes
Respiratory Disorder During Sleep in the Pregnancy : A Risk Factor in Gestational Diabetese
Introduction: The pregnancy brings about physiological and hormonal modifications which cause sleep disorder. The sleeplessness, snoring and a bad sleepquality are frequent during the pregnancy.
- Trial name
- NCT02756442
- Testing
- Respiratory disorder assessment during sleep
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Chronic Kidney Diseases
Zibotentan and Dapagliflozin in Patients With Type 2 Diabetes and Elevated Albuminuria
The aim of this study is to test the hypothesis that the effects on albuminuria of combination treatment with the endothelin receptor antagonist zibotentan and SGLT2i dapagliflozin are complimentary and additive while the fluid…
- Trial name
- ZODIAC (NCT05570305)
- Testing
- Zibotentan, Dapagliflozin, Dapagliflozin and Zibotentan
- Where
- 7 sites in United States, Canada and 3 more
- Volunteers
- 42 people
- Sponsor
- University Medical Center Groningen
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