Clinical trials: Diabetes or Diabetes Prevention
Diabetes
Relationship Between Oral Health and Diabetes
The aim of this study is to assess the state of knowledge and practices in oral health of diabetic patients through the use of two questionnaires.
- Trial name
- NCT04991168
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cardiovascular Disease
Cardiovascular Inflammation Reduction Trial
The Cardiovascular Inflammation Reduction Trial (CIRT) is a randomized clinical trial investigating whether taking low-dose methotrexate reduces heart attacks, strokes, or death in people with type 2 diabetes or metabolic…
- Trial name
- CIRT (NCT01594333)
- Testing
- Methotrexate
- Where
- 470 sites in United States, Canada and 1 more
- Volunteers
- 4,786 people
- Sponsor
- Brigham and Women's Hospital
Diabetes
Describing the Clinical-laboratory Aspects of Diabetes Through the Creation of a Registry
The main objective of the study is to describe the clinical-laboratory aspects of diabetes by creating a registry in which to census all newly diagnosed or already diagnosed cases after 1/1/2000 at the O.U.
- Trial name
- NCT06797947
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Metabolic Syndrome
Effect of a High-Protein Diet and/or High-Intensity Training on Metabolic Syndrome
The objective of this study is to determine the combined effects of a high-protein diet and high-intensity training on metabolic syndrome risk factors in women aged 30-65.
- Trial name
- EPHIT (NCT01622634)
- Testing
- Sprint Interval Exercise, Higher PRO Diet, Higher CARB Diet
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Type 2 Diabetes
Middle-School Based Primary Prevention Trial of Type 2 Diabetes
HEALTHY was a primary prevention trial conducted in 42 middle schools at 7 locations across the US to impact risk factors for type 2 diabetes in adolescents.
- Trial name
- HEALTHY (NCT00458029)
- Testing
- integrated program of nutrition, activity, behavior, and promotion
- Where
- 8 sites in United States
- Volunteers
- 4,603 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 2
Long-term Study of Nateglinide+Valsartan to Prevent or Delay Type II Diabetes Mellitus and Cardiovascular Complications
This study is a test of the safety and effectiveness of two drugs, one for diabetes and one for hypertension, in keeping patients with high lab values of glucose from progressing to frank diabetes and developing cardiovascular…
- Trial name
- Navigator (NCT00097786)
- Testing
- Valsartan 160 mg + nateglinide 60 mg
- Where
- 38 sites in United States, Argentina and 36 more
- Volunteers
- 9,306 people
- Sponsor
- Novartis Pharmaceuticals
Post Coronary Artery Bypass Grafting, Hypertension
"Smart Family Doctor" Assisted Comprehensive Management of Secondary Prevention Among Post Coronary Artery Bypass Graft Patients or Post Percutaneous Coronary Intervention Patients
This study aims to evaluate the effect of an AI-assisted "Smart family doctor" digital health management tool on improving the control rates of hypertension, diabetes, and dyslipidemia in post-CABG (coronary artery bypass…
- Conditions
- Post Coronary Artery Bypass Grafting, Hypertension, Diabetes Mellitus, Hyperlipidemia
- Trial name
- SMART (NCT06615609)
- Testing
- Smart family doctor, Health manager
- Where
- China
- Volunteers
- 536 people
- Sponsor
- China National Center for Cardiovascular Diseases
Type 1 Diabetes, Dermatologic Complication
Prevention of Skin Problems With Diabetes Devices in Pediatric Patients
A Cluster-controlled Intervention Trial regarding Prevention of Dermatological Complications towards use of Continuous glucose monitoring and insulin pumps in pediatric patients with Type 1 Diabetes.
- Trial name
- NCT04258904
- Testing
- Skin Care Program
- Where
- Denmark
- Volunteers
- 236 people
- Sponsor
- Copenhagen University Hospital at Herlev
Type 2 Diabetes
Prevention and Treatment Of Diabetes Complications With Gastric Surgery or Intensive Medicines
The obesity and type 2 diabetes mellitus (T2DM) are among the most threatening health crisis for the 21st century. Currently, it is estimated that there are 205 million people with T2DM worldwide.
- Trial name
- PRODIGIES (NCT01974544)
- Testing
- Best medical treatment, gastric bypass, sleeve gastrectomy
- Where
- Chile
- Volunteers
- 150 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Prediabetic State
Rimonabant In Prediabetic Subjects To Delay Onset Of Type 2 Diabetes
Primary objective: To evaluate the effect of long-term administration of Rimonabant on the time of progression to type 2 diabetes in patients with prediabetes (i.e.
- Trial name
- RAPSODI (NCT00325650)
- Testing
- Rimonabant
- Where
- United States
- Volunteers
- 2,420 people
- Sponsor
- Sanofi
Ethnic Group, Young Adults
Diabetes Prevention in Prediabetic Patients
This study will evaluate the feasibility and efficacy of two interventions of lifestyle ( intensive and less intensive) to prevent diabetes in patients from Ethiopian origin, aged 25 to 55 years old with prediabetes living in…
- Conditions
- Ethnic Group, Young Adults, Prediabetes, Community Health Services
- Trial name
- DPEP (NCT01659697)
- Testing
- intensive lifestyle counseling
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
Overweight or Obesity, Pregnancy
DPP Feasibility Study of Breastfeeding - eMOMS 2.0
The purpose of this study is to investigate the impact of a comprehensive intervention that combines breastfeeding support with a diabetes prevention-based program (DPP) on postpartum weight retention and lactation duration among…
- Trial name
- NCT06372860
- Testing
- Diabetes Prevention Program, Breastfeeding, Usual Care
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Kansas Medical Center
Atherosclerosis, Chronic Kidney Diseases
The ILERVAS Project: Assessing the Prevalence of Subclinical Vascular Disease and Hidden Kidney Disease
BACKGROUND AND OBJECTIVES: Cardiovascular disease is the leading cause of death despite huge primary and secondary prevention policies with a strong economic burden.
- Conditions
- Atherosclerosis, Chronic Kidney Diseases, Metabolic Syndrome, PreDiabetes
- Trial name
- ILERVAS (NCT03228459)
- Testing
- Dried blood spot test, Urine test, Artery ultrasound
- Where
- 3 sites in Spain
- Volunteers
- 16,660 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Overweight or Obesity
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
The goal of this clinical trial is to test an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) that is tailored to young women in childbearing years.
- Trial name
- NCT05674799
- Testing
- NDPP-NextGen
- Where
- United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity, Weight Loss
Obesity Treatment With a Very Low Energy Diet in Mexican Adults
Clinical practice guidelines recommend behavioral change protocols for obesity treatment, such as the Diabetes Prevention Program, which involves a low-energy diet, physical activity recommendations, behavioral therapy, and…
- Trial name
- NCT05631535
- Testing
- Intensive lifestyle change program with a very-low-energy diet, Intensive lifestyle change program with a low-energy diet
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Universidad de Sonora
Hyperlipidemias, Atherosclerosis
Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets
A cholesterol/lipid profile screening project of high risk patients with hyperlipidaemia (secondary prevention) who already receive cholesterol-lowering therapy.
- Conditions
- Hyperlipidemias, Atherosclerosis, Coronary Heart Disease, Carotid Stenosis
- Trial name
- NCT00536965
- Where
- Austria
- Volunteers
- 951 people
- Sponsor
- AstraZeneca
Infections Joint Prosthetic, Overweight or Obesity
Antibiotic Prophylaxis in High-Risk Arthroplasty Patients
To determine the effectiveness of a 7-day course of an oral, prophylactic antibiotic on the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk…
- Conditions
- Infections Joint Prosthetic, Overweight or Obesity, MSSA Colonization, MRSA
- Trial name
- NCT04297592
- Testing
- Cephalexin, Doxycycline, Cefadroxil
- Where
- 2 sites in United States
- Volunteers
- 4,618 people
- Sponsor
- Mayo Clinic
Obesity or Overweight
Obesity Treatment Using an Internet-delivered Intervention Based on the Diabetes Prevention Program in Mexican Adults
In Mexico, 7 out of 10 adults are overweight or obese. The diseases associated with these conditions (diabetes, cardiovascular disease and some cancers) are those that impact the most on the disability-adjusted life years of…
- Trial name
- DPPON-MEX (NCT03629301)
- Testing
- ID-DPP group, Wait-list Group
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Universidad de Sonora
Diabetes Mellitus, Type 2
Subjects With T2D or at Risk of T2D Cohort Follow-up
The main objective of this study is to prospectively follow the subjects included in "Descendance" cohort and to describe the occurrence of type 2 diabetes in non-diabetic subjects, which will allow us to iteratively update the…
- Trial name
- DESCENDANCE (NCT05567692)
- Testing
- OGTT, HbA1c, Questionnaire
- Where
- France
- Volunteers
- 837 people, healthy volunteers welcome
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Non-communicable Diseases (NCD), Neoplams
Health for Hungary (H4H) - Longitudinal Collection of Blood Samples and Corresponding Data
The Health for Hungary (H4H) study collects blood samples and corresponding health data to investigate healthy aging and health-to-disease transitions in middle-aged and elderly participants.
- Conditions
- Non-communicable Diseases (NCD), Neoplams, Cancer, Lung Cancer (NSCLC)
- Trial name
- H4H (NCT07743021)
- Where
- 33 sites in Hungary
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Center for Molecular Fingerprinting Research Nonprofit LLC