Clinical trials: Diabetes type2
Diabetes Mellitus, Type 2, Educational Problems
The Effect of Web-Based Education in Patients With Type 2 Diabetes
This research was designed as a randomized controlled study to develop a web-based training program and evaluate the program's impact on diabetes management.
- Trial name
- NCT04626531
- Testing
- Web-Based Education, Control Group
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Obesity, Type 2 Diabetes Mellitus
Effect of Pre-meal Serving of Dairy and Dairy Alternatives on Post-meal Satiety and Glycaemia in Healthy Young Adults
Regular consumption of dairy products is found to negatively associated with metabolic diseases and improve body composition in long term studies and has positive effect on acute glycemia control and satiety.
- Trial name
- NCT04600128
- Testing
- Dairy-based greek yogurt, Dairy-based cheddar cheese, Plant-based yogurt
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes
Conditional Cash Transfer Intervention to Improve T2DM
This study will test the preliminary efficacy of diabetes-tailored CCT (DM-CCT), which will be conditional on participating in biweekly (every two weeks), nurse-led, virtual diabetes education/skills training and stress/coping…
- Trial name
- DMCT (NCT05559892)
- Testing
- DM-CCT, DM-UCT
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Healthy Subjects, Obesity
A Phase 1 Study of HEC88473 Injection in Healthy Subjects, Obese Subjects and T2DM Subjects
This is a single-center, randomized, double-blind, placebo-controlled, escalating single-dose and multiple-dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HEC88473 injection in healthy…
- Conditions
- Healthy Subjects, Obesity, T2DM (Type 2 Diabetes Mellitus)
- Trial name
- NCT05943886
- Testing
- HEC88473 injection
- Where
- China
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Dongguan HEC Biopharmaceutical R&D Co., Ltd.
Diabetes Mellitus, Type 2
Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Extended Release Metformin and Extended Release Glimepiride in Health Volunteers
This is a an open-label, randomized, single dose, four-way crossover, multi-stage study enrolling 20 healthy adult male and female subjects per part.
- Trial name
- NCT01725672
- Testing
- Metformin, 500 mg extended release tablet, Metformin, 1000 mg extended release tablet, Glimepiride, 1 mg immediate release tablet
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus, Type 2, Diabetic Foot
Non-invasive Imaging for In-vivo Quantification of Skin Composition and Structure
The goal of this clinical investigation is to explore a non-invasive technology for measuring the microcirculatory structure, composition and function in patients from a primary care population. The main aims are: 1.
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Foot, Peripheral Arterial Disease, Skin Cancer
- Trial name
- Spectrum1 (NCT06976073)
- Where
- 3 sites in Sweden
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- HJN Sverige AB/Neko Health
Type 2 Diabetes
Prevention of Type 2 Diabetes Amongst South Asians With Central Obesity and Prediabetes
The investigators' general goal is to identify approaches to risk stratification and health promotion through lifestyle modification that are acceptable, effective and efficient for prevention of T2D in South Asian communities…
- Trial name
- iHealth-T2D (NCT02949739)
- Testing
- Intensive lifestyle modification
- Where
- United Kingdom
- Volunteers
- 5,244 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity, Type 2 Diabetes Mellitus
XW004 To Evaluate the Safety, Tolerability, PK, and PD of Oral Ecnoglutide Tablet in Healthy Adults
XW004 is an acylated human glucagon-like peptide 1 (GLP-1) analogue and is being developed for type 2 diabetes mellitus (T2DM) and obesity management.
- Trial name
- NCT05184322
- Testing
- T2026, Oral ecnoglutide tablet
- Where
- Australia
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Sciwind Biosciences APAC CO Pty. Ltd.
Diabetes Mellitus, Type 2
Cognitive Training for Diabetes Self-Management
The overall objective of this study is to determine the effects of a comprehensive cognitive rehabilitation intervention on biological, cognitive, and diabetes self-management outcomes.
- Trial name
- NCT04831775
- Testing
- Memory, Attention, and Problem Solving Skills for Diabetes, Brain Games
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Diabetes Mellitus, Type 2
Raclopride-PET/MRT
Cerebral insulin resistance plays an important role in the development of obesity and diabetes mellitus type 2. The aim of this project is to examine the effect of human nasal insulin on the dopaminergic system.
- Trial name
- NCT03637075
- Testing
- intranasal insulin
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Dry Eye Syndrome, Diabetes Mellitus Type 2
Comparison of Ocular Surface Features in Patients With Diabetes and Dry Eye Syndrome
The study aims to compare the differences of ocular surface features in controls and patients with diabetes and dry eye syndrome, to thoroughly evaluate the ocular surface health of diabetics, and to find out the relationship…
- Trial name
- NCT03576300
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Acromegaly, Type 2 Diabetes Mellitus
Growth Hormone Feedback to Insulin-like Growth Factor-I (IGF-1) and Oral Glucose Tolerance Test (OGTT)
Growth hormone (GH) and Insulin-like growth factor-I (IGF-I) secretion are altered in acromegaly and type 2 Diabetes Mellitis (DM).
- Trial name
- NCT00915954
- Testing
- Oral Glucose Tolerance Test, Subcutaneous administration of recombinant human IGF-1
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Diabetes Mellitus, Type 2
Acute Effects of Aerobic Exercise on Flow Mediated Slowing and Flow Mediated Dilation in Adults With and Without Type 2 Diabetes
The endothelium is a protective lining of cells inside blood vessels. It keeps blood vessels working smoothly by controlling how wide or narrow your blood vessels are and protecting them from damage.
- Trial name
- ARM WRESTLING (NCT06684912)
- Testing
- High-intensity interval exercise, Moderate continuous exercise
- Where
- Portugal
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Type 2 Diabetes
Myocardial Perfusion in Type 2 Diabetes
The investigators aimed to evaluate microvascular circulation with novel method: real-time myocardial contrast echocardiography in patients with type 2 diabetes and normal coronary arteries.
- Trial name
- NCT01043965
- Testing
- Metformin
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Healthy
A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants
The purpose of this study is to assess the bioequivalence (similarity of the drug amount in blood among the formulations) of the fixed dose combination (two components combined in one tablet) of canagliflozin and metformin…
- Trial name
- NCT02077803
- Testing
- Canagliflozin, 100 mg, Metformin XR, 500 mg, CANA/MET XR FDC, Formulation 1, 50 mg/1000 mg
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Type 2 Diabetes Mellitus, Obesity
Inulin,SCFA Production and Metabolic Response
In this placebo controlled, double-blind, randomized crossover study the investigators will investigate in overweight/obese healthy male volunteers whether inulin administration will increase intestinal SCFA production, thereby…
- Trial name
- NCT02009670
- Testing
- 13C inulin
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Type 2 Diabetes, Obesity, Prediabetes
The Influence of Glucose Flux on Fat Synthesis in a Whole Body Calorimeter
The study is carried out to find out the inclusion of high and low glycaemic index foods to daily meals and how they impact 24 hour blood glucose fluctuations and energy regulation.
- Trial name
- NCT02631083
- Testing
- Breakfast, lunch, snack and dinner
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Insulin Sensitivity
The Potential of Carnosine Supplementation in Reducing the Cardiometabolic Risk
The aim of this study is to determine whether carnosine supplementation in overweight/obese individuals can improve insulin secretion and/or insulin resistance by decreasing sub clinical inflammation.
- Trial name
- NCT02686996
- Testing
- carnosine
- Where
- Australia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Monash University
Diabetes Mellitus, Type 2
A Single-dose Phase 1 Study of DBPR108 in Healthy Male Subjects
The study is being performed to assess the safety, tolerability, and pharmacokinetic (PK) and pharmacodynamic (PD) properties of single oral doses of DBPR108 in healthy male subjects.
- Trial name
- NCT01650324
- Testing
- DBPR108
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Cardiovascular Risk Factor, Type2 Diabetes
Breaking up Sitting With a Treadmill Desk in Office Workers
Sitting for long uninterrupted periods of time can increase risk of heart disease, diabetes and early death, even if you take part in the United Kingdom government guidelines for physical activity of 21/2 hours per week of…
- Conditions
- Cardiovascular Risk Factor, Type2 Diabetes, Sedentary Lifestyle
- Trial name
- NCT03468894
- Testing
- Treadmill desk walking
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Bedfordshire
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