Clinical trials: Diabetes type2
Obesity, Type2 Diabetes
Cardiovascular Outcomes in Bariatric Surgery Patients With Type 2 Diabetes
The objective of the analysis was to evaluate the relationship between bariatric surgery and cardiovascular outcomes in obese patients with type 2 diabetes.
- Conditions
- Obesity, Type2 Diabetes, Bariatric Surgery Candidate
- Trial name
- NCT03955952
- Testing
- Bariatric Surgery
- Where
- United States
- Volunteers
- 91,700 people
- Sponsor
- The Cleveland Clinic
Diabetic Kidney Disease, Hyperuricemia
Uric Acid Lowering Trial in Youth Onset T2D
Adolescents and young adults with youth-onset type 2 diabetes (T2D) are disproportionally impacted by hyperuricemia compared to non-diabetic peers and youth with type 1 diabetes (T1D).
- Conditions
- Diabetic Kidney Disease, Hyperuricemia, Diabetes, Diabetes Mellitus, Type 2
- Trial name
- ULTRA-T2D (NCT03899883)
- Testing
- Pegloticase 8 MG/ML [Krystexxa]
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Colorado, Denver
Breast Cancer, Coronary Artery Disease
Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity
This study is about testing whether exercise will improve fitness and lessen risk factors related to heart disease, diabetes, and obesity in Latina breast cancer survivors.
- Conditions
- Breast Cancer, Coronary Artery Disease, Stroke, Type2 Diabetes
- Trial name
- NCT04717050
- Testing
- Progressive combine training (PCT), Attention Control (AC)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Dana-Farber Cancer Institute
Diabetes Mellitus, Type 2, Diabetes
Dietary Approaches to Stop Hypertension for Diabetes
The objective of the DASH4D trial is to determine the effects, alone and combined, of (a) the DASH4D diet (a DASH-style diet modified for people with diabetes) vs.
- Conditions
- Diabetes Mellitus, Type 2, Diabetes, Diabetes type2, Type2 Diabetes
- Trial name
- DASH4D (NCT04286555)
- Testing
- DASH4D diet, comparison diet, higher sodium
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Johns Hopkins University
Atherosclerotic Vascular Disease, Type2 Diabetes
The Effects of Evolocumab in Patients With Diabetes and Atherosclerotic Vascular Disease
Experimental models have linked lipid lowering therapies with systemic inflammation; however, relatively little is known about this network in clinical populations and specifically how it changes with PCSK9 inhibition.
- Conditions
- Atherosclerotic Vascular Disease, Type2 Diabetes, Microvascular Dysfunction
- Trial name
- NCT03829046
- Testing
- Evolocumab
- Where
- 2 sites in United States, Canada
- Volunteers
- 41 people
- Sponsor
- Robert Rosenson
Physical Inactivity, Type2 Diabetes Mellitus
Behavioral Change Communication for Physical Activity Among Females With Type2 Diabetes Mellitus
The marked discrepancy between predicted and actual prevalence of Type2 diabetes Mellitus (DM) with the actual cases rising earlier than expected, underscore the continuing relevance of tailored awareness and management…
- Trial name
- RCT (NCT00690326)
- Testing
- Behavioral change communication model(BCC) to promote physical activity, pamphlet-The printed pamphlet,'Physical activity:To control blood sugar/ Diabetes Mellitus'
- Where
- India
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Thiruvananthapuram Medical College
Overweight and Obesity, Type2 Diabetes
The Mobile Lifestyle Intervention for Food and Exercise Study
The goal of the study is to examine long term sustained weight loss digital intervention in a diverse cohort of adults with overweight/obesity.
- Trial name
- mLIFE (NCT05176847)
- Testing
- Podcasts and tips of the day (within app), mLIFE app (self-regulation features), mLIFE app (social support features)
- Where
- United States
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Cardiovascular Risk Factor, Type2 Diabetes Mellitus
Orange Juice And Sugar Intervention Study
The objectives of this proposal are to address the gaps in knowledge regarding the metabolic effects of consuming orange juice, the most frequently consumed fruit juice in this country, compared to sugar-sweetened beverage.
- Conditions
- Cardiovascular Risk Factor, Type2 Diabetes Mellitus, Insulin Sensitivity, Metabolic Syndrome
- Trial name
- OASIS (NCT03527277)
- Testing
- Naturally-sweetened orange juice, Sugar-sweetened beverage
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Type2 Diabetes
OP5-005 Using Omnipod 5 in Adults With Type 2
This is a single arm, multi-center, prospective study that will evaluate the safety and efficacy of the Omnipod 5 Automated Insulin Delivery System in adults with type 2 diabetes requiring insulin therapy.
- Trial name
- SECURE-T2D (NCT05815342)
- Testing
- Omnipod 5 Automated Glucose Control System
- Where
- 21 sites in United States
- Volunteers
- 343 people
- Sponsor
- Insulet Corporation
Type2 Diabetes, Diabetes Mellitus
A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both
The purpose of this study is to learn more about the safety and efficacy of tirzepatide compared to placebo in children or teenagers with type 2 diabetes taking metformin, or basal insulin, or both.
- Conditions
- Type2 Diabetes, Diabetes Mellitus, Diabetes Mellitus, Type 2, T2D
- Trial name
- SURPASS-PEDS (NCT05260021)
- Testing
- Tirzepatide Dose 1, Tirzepatide Dose 2
- Where
- 51 sites in United States, Australia and 7 more
- Volunteers
- 99 people
- Sponsor
- Eli Lilly and Company
Type2 Diabetes, Dyslipidemia
Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)
The primary objective of the study is to determine whether pemafibrate administered twice daily will delay the time to first occurrence of any component of the clinical composite endpoint of: nonfatal Myocardial Infarction (MI)…
- Trial name
- PROMINENT (NCT03071692)
- Testing
- K-877
- Where
- 888 sites in United States, Argentina and 23 more
- Volunteers
- 10,544 people
- Sponsor
- Kowa Research Institute, Inc.
Type2 Diabetes, Coronary Artery Disease
Liraglutide Effects on Epicardial Fat Inflammatory Genes
Epicardial adipose tissue (EAT) is the visceral fat of the heart. EAT could locally affect the coronary arteries through local secretion of pro-inflammatory cytokines.
- Trial name
- NCT03260881
- Testing
- Liraglutide Pen Injector [Victoza]
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Miami
Type2 Diabetes
A Mobile Health Intervention to Reduce Diabetes Disparities in Chinese Americans
Chinese Americans are one of the fastest growing immigrant groups in the US, who suffer disproportionately high type 2 diabetes (T2D) burden and have poorly controlled T2D.
- Trial name
- NCT03557697
- Testing
- Standard of Care, SMS Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Type2 Diabetes
i-Matter: Investigating an mHealth Texting Tool for Embedding Patient-reported Data Into Diabetes Management
This study will integrate a technology-based patient-reported outcome (PRO) system [herein MJS DIABETES] that incorporates patients' perspective of their disease and functional status into the management of type 2 diabetes (T2D)…
- Trial name
- NCT03652389
- Testing
- MJS Diabetes
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- NYU Langone Health
Obese With Comorbidities, Overweight With Comorbidities
Study for Multiple Doses of HM15136(Efpegerglucagon) in Obese or Overweight Subjects With Comorbidities
The planned period of each cohort is 22 weeks including subject screening, treatments for 12 weeks, and follow up period.
- Conditions
- Obese With Comorbidities, Overweight With Comorbidities, Type2 Diabetes
- Trial name
- NCT04167553
- Testing
- HM15136
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Type2 Diabetes
The Effect of Hypoxia on Type 2 Diabetes and Weight Loss
The number of people with type 2 diabetes mellitus (T2DM) continuing to rise, this pandemic is expected to reach 700 million people by 2045.
- Trial name
- NCT05147116
- Testing
- Sleeping in a tent
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- University of Portsmouth
Type2 Diabetes
Chronic Passive Heating in Individuals With T2DM
Type 2 diabetes mellitus (T2DM) is a metabolic condition characterized by chronic hyperglycemia and progressive insulin resistance, which progressively lead to macro- and microvascular damage and subsequent impairments in blood…
- Trial name
- NCT04858321
- Testing
- Passive heating
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Portsmouth
Type2 Diabetes
Social Network Analysis to Identify Community Health Workers
The objective of this study is to recruit influential community members using Snowball Sampling Methods. Community members identified through social network analysis as influential and well-connected will be trained as community…
- Trial name
- NCT04210024
- Testing
- Diabetes Empowerment Education Program
- Where
- 2 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Brittany L Smalls
Type2 Diabetes, Heart Failure
Effect of Ertugliflozin on Cardiac Function in Diabetes
The aim of this study is to investigate the beneficial role of ertugliflozin, a new SGLT2 inhibitor, in cardiac function via measuring GLS as well as other hemodynamic factors using echocardiogram in patients with T2D and HF, who…
- Trial name
- ERTU-GLS (NCT03717194)
- Testing
- Ertugliflozin
- Where
- South Korea
- Volunteers
- 102 people
- Sponsor
- Soo Lim
Type2 Diabetes
Stories for Change: Digital Storytelling for Diabetes Self-Management Among Hispanic Adults
Hispanic adults are twice as likely to have type 2 diabetes mellitus (T2D) and 1.5 times more likely to die from the disease than non-Hispanic whites.
- Trial name
- S4C (NCT03766438)
- Testing
- Digital Storytelling Intervention
- Where
- 3 sites in United States
- Volunteers
- 451 people
- Sponsor
- Mayo Clinic