Clinical trials: Diabetes-Related Complications
Diabetic Complication, Covid19 Virus Infection
Suspicion of Hypoglycemic Effect of mRNA Based Covid-19 Vaccines (Polyethylene Glycol) Will Happen , Observational Study on Diabetic Patients at Saudia Arabia
vaccines for covid-19 are gold strategy and great achievement at this century for protection against complications of covid-19 , development of many vaccines with different technology represent a big challenge for this disease so…
- Conditions
- Diabetic Complication, Covid19 Virus Infection, Hypoglycemia, Polyethylene Glycol Adverse Reaction
- Trial name
- NCT05087225
- Testing
- polyethelyene glycol
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Saudi Arabia
Autosomal Dominant Polycystic Kidney Disease (ADPKD), Advanced-Chronic Kidney Disease (CKD)
Establishment of the Human Intestinal and Salivary Microbiota Biobank - Kidney Diseases
This is a prospective, clinical, multicentre study aimed to collect biological samples and study microbiota from subjects suffering from chronic kidney disease and from healthy volunteers.
- Conditions
- Autosomal Dominant Polycystic Kidney Disease (ADPKD), Advanced-Chronic Kidney Disease (CKD), Diabetic Kidney Disease (DKD), IgA Nephropathy (IgAN)
- Trial name
- BIOMIS-Nefro (NCT04689074)
- Testing
- Biological sample collection, Questionnaire, Medical examination
- Where
- 2 sites in Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Diabetic Nephropathy
The Significance of Urine UbA52 In the Diagnosis of Diabetic Nephropathy
Definite diagnosis of diabetic nephropathy is currently based on renal biopsy findings. In most cases, however, the diagnosis can be reliably made in patients with macroalbuminuria in the presence of diabetic…
- Trial name
- NCT02204280
- Volunteers
- 120 people
- Sponsor
- Hebei Medical University Third Hospital
Diabetic Foot Ulcer
Intensive Glycemic Control For Diabetic Foot Ulcer Healing
With the available molecular and cellular evidence of impaired wound healing due to hyperglycemia, investigators postulate hypothesis asking whether intensive glycemic control could improve diabetic foot ulcer healing rates.
- Trial name
- INGLOBE (NCT04323462)
- Testing
- Insulin Glargine, Diabetic DM
- Where
- 2 sites in India
- Volunteers
- 326 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Diabetic Nephropathies
Possible Role of Roflumilast in Diabetic Nephropathy
adding roflumilast to the standard therapy for diabetic nephropathy and studying the progression of many outcomes including urinary albumin to creatinine ratio, estimated GFR, biomarkers of diabetic nephropathy
- Trial name
- NCT04755946
- Testing
- Roflumilast
- Volunteers
- 48 people
- Sponsor
- Tanta University
Diabetic Kidney Disease
Association of BsmI Polymorphisms in Vitamin D Receptor Gene With Diabetic Kidney Disease
Background: Diabetic kidney disease (DKD), as one of chronic complication of type 2 diabetes mellitus, is common cause of end stage renal disease (ESRD). Vitamin D deficiency is known as one of DKD risk factors.
- Trial name
- NCT03621384
- Where
- Indonesia
- Volunteers
- 93 people
- Sponsor
- Universitas Indonesia
Diabetic Neuropathies, Neuropathic Pain
Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy
This study evaluates the analgesic effect of Omnitram for the treatment of painful diabetic neuropathy. Each subject with diabetic neuropathy will be treated for four weeks with Omnitram and for four weeks with placebo.
- Conditions
- Diabetic Neuropathies, Neuropathic Pain, Pain, Chronic
- Trial name
- NCT03664921
- Testing
- Omnitram Oral Tablet
- Where
- 4 sites in United States
- Volunteers
- 55 people
- Sponsor
- Syntrix Biosystems, Inc.
Diabetic Retinopathy
Effect of SGLT2i on Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients
A prospective, randomized, open-label, controlled clinical trial will be conducted at the endocrinology department - Ain Shams University (ASU) hospital. Sixty patients will be enrolled into the study.
- Trial name
- NCT05310916
- Testing
- Dapagliflozin 10mg Tab plus another oral hypoglycemic agent, Two oral hypoglycemic agents other than dapagliflozin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Nidae Alaa
Wound
Evaluation of the Safety and Effectiveness of ALLEVYN Gentle Border
The clinical study will evaluate the safety and effectiveness of the ALLEVYN Gentle Border. The study is a post-market clinical follow-up to assess clinical performance and safety of ALLEVYN Gentle Border with new wound contact…
- Trial name
- NCT03877484
- Testing
- ALLEVYN Gentle border
- Where
- 6 sites in France, Germany and 1 more
- Volunteers
- 43 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Diabetic Retinopathy
Pharmacological Intervention in Diabetic Retinopathy
The purpose of this study is to determine if diabetic retinopathy can be treated with prostaglandin analogues, prostaglandin synthesis inhibitors or carbonic anhydrases inhibitors.
- Trial name
- XAVOT (NCT00619034)
- Testing
- Latanoprost, diclofenac and dorzolamide (eyedrops), Diclofenac, Dorzolamide
- Where
- Denmark
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Diabetes Mellitus, Diabetes Complications
A Fruit and Vegetable Prescription Program
Dietary intake of fruits and vegetables (F\&V) is a cornerstone for the treatment of type 2 diabetes, however less than 16% of Hispanic adults consume the recommended number of servings each day.
- Trial name
- NCT06107816
- Testing
- Usual Care, F&V Rx alone, F&V Rx plus DSME/S
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Milton S. Hershey Medical Center
Diabetes, Neuropathic Foot
A Comparison of Insoles Used to Prevent Neuropathic Diabetic Foot Ulceration
Importance of the topic: Lower extremity amputation is a costly complication of diabetes for both the NHS and the patient. Amputation may be avoided if the preceding foot ulceration can be prevented.
- Trial name
- NCT00999635
- Testing
- Insole
- Where
- 2 sites in United Kingdom
- Volunteers
- 119 people
- Sponsor
- University of Plymouth
Neuropathic Pain
Donepezil Compared to Placebo in Patients With Chronic Neuropathic Pain
Based on laboratory studies, donepezil will improve pain relief more than placebo in patients with chronic neuropathic pain who are currently taking gabapentin or pregabalin.
- Trial name
- NCT01743976
- Testing
- Donepezil
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Wake Forest University
Diabetic Foot Ulcer
Outcomes of Irrisept Irrigation as an Adjunctive Treatment in the Management of Diabetic Foot Ulcers
Irrisept™ irrigation containing Chlorhexidine Gluconate (CHG) 0.05% in sterile water, is an irrigation method that may help reduce bacterial load considerably more than traditional saline irrigation.
- Trial name
- NCT06024590
- Testing
- Irrisept, Saline
- Where
- 5 sites in United States
- Volunteers
- 9 people
- Sponsor
- Northern Illinois Foot and Ankle Specialists
Retinal Disease, Corneal Disease
Tissue Studies of Human Eye Diseases
The purpose of this project is to diagnose and evaluate ocular and related tissues with various diseases such as conjunctival, corneal, uveal, vitreoretinal and optic nerve disorders, ocular degenerative, metabolic or genetic…
- Conditions
- Retinal Disease, Corneal Disease, Diabetic Retinopathy, Uveitis
- Trial name
- NCT00001310
- Where
- United States
- Volunteers
- 3,833 people
- Sponsor
- National Eye Institute (NEI)
Diabetic Foot Ulcer Neuropathic
Hyperbaric Oxygen Therapy in Diabetic Foot
This study seeks to assess changes in genes that are related to inflammation and oxidative stress in patients with type 2 Diabetes with diabetic foot treated with hyperbaric chamber
- Trial name
- HBOTDF (NCT06502808)
- Testing
- Hyperbaric oxygen therapy
- Where
- Mexico
- Volunteers
- 15 people
- Sponsor
- National Polytechnic Institute, Mexico
Diabetic Foot
Trial of Vacuum Assisted Closure® Therapy in Amputation Wounds of the Diabetic Foot
The purpose of this study is to compare the effectiveness of Vacuum Assisted Closure® (V.A.C.®) Therapy to moist wound therapy of amputation wounds of the diabetic foot.
- Trial name
- NCT00224796
- Testing
- V.A.C. ® System
- Volunteers
- 146 people
- Sponsor
- KCI USA, Inc
Diabetic Retinopathy
PST/Laser v. Laser Alone for CSME
Prospective randomized clinical trial comparing Laser Alone v. Laser and posterior sub-tenon injection of triamcinolone acetonide for primary and refractory clinically significant macular edema.
- Trial name
- NCT00229918
- Testing
- triamcinolone acetonide
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Edward Hines Jr. VA Hospital
Diabetes
Effect of E Balance Pro Therapy on Diabetes and Related Complications
This is an observational study, to test the hypothesis that E Balance Pro Therapy micro-current treatments, delivered with precision in amplitude, waveform and pulsing pattern, adapted by other aspects of this device's technology…
- Trial name
- NCT03172260
- Testing
- E Balance Pro Therapy
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- CellMedX Corporation
Fetal Macrosomia
DAME: Induction of Labor or Waiting for Suspicion Fetal Macrosomia
Aim of the study :The major aim is to evaluate the effectiveness of the induction of labor in case of fetal macrosomia on the reduction of neonatal traumatism risk.
- Trial name
- NCT00190320
- Testing
- Induction of labor vs waiting
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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