Clinical trials: Diabetic Feet
Diabetic Foot Ulcer
The Effects of Vacuum-Compression Therapy on the Healing of Diabetic Foot Ulcers
the objective of this study is to evaluate the impact of vacuum-compression effects of Vasotrain on the diabetic foot ulcers using stereological method based on Cavalieri's principle in diabetic patients.
- Trial name
- VCT (NCT00477022)
- Testing
- Vasotrain-447
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Zahedan University of Medical Sciences
Diabetic Foot Ulcer
Custom Insole With Transcutaneous Electrical Nerve Stimulation on Clinical Outcomes of Diabetic Foot Ulcers
Diabetic foot ulcers (DFUs) are one of the serious complications of diabetes, typically resulting from neuropathy or peripheral arterial disease, and can often lead to amputation.
- Trial name
- NCT07109895
- Testing
- Standard Care Only, Custom Insole + Standard Care, TENS + Custom Insole + Standard Care
- Where
- Pakistan
- Volunteers
- 159 people
- Sponsor
- University of Lahore
Diabetic Foot Ulcers
Effectiveness of Buerger Allen Exercise Among Type 2 Diabetes Mellitus Patients With Foot Ulcer
This study was conducted to determine the effect of Buerger Allen exercises on lower extremity perfusion and wound healing in patients with foot ulcer type 2 diabetes.
- Trial name
- NCT05747872
- Testing
- Buerger Allen Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Gazi University
Diabetic Foot, Wound Healing Delayed
Ultrasonic Enhancement Delivery of Phosphodiesterase Inhibitors Nanoparticles for Diabetic Management of the Foot
The enhancement of cGMP levels at the wound site has shown beneficial effects in wound healing. Thus, topical or systemic application of phosphodiesterase 5 (PDE5) inhibitors, for example, sildenafil (Viagra), which is well-known…
- Conditions
- Diabetic Foot, Wound Healing Delayed, Diabete Mellitus, Amputation
- Trial name
- NCT07690566
- Testing
- Tadalafil
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Deraya University
Diabetic Foot, Diabetic Foot Ulcer
Effectiveness of the Autologous Adipose Tissue Harvested With SEFFICARE Method for Treatment of DFU Minor Amputation
Diabetic foot ulcers (DFU) are one of the complications of diabetes mellitus resulting from multiple causes such as neuropathy, ischemia, and infection that contribute to morbidity and amputation.
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Amputation
- Trial name
- SEFFIDiFA (NCT05072353)
- Testing
- SEFFICARE
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Diabetic Foot Ulcer
Multi Center Site , Controlled Trial Comparing a Bioengineered Skin Substitute to a Human Skin Allograft
Despite the widespread use of advanced biologics for the treatment of diabetic foot ulcers, data comparing one type of modality to another are scarce.
- Trial name
- NCT01676272
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Solsys Medical LLC
Diabetic Foot Ulcer, Diabetic Foot
Exercise Therapy for People With a Diabetic Foot Ulcer - a Feasibility Study
The aim of this feasibility study is to evaluate a 12-week exercise intervention in people with an active diabetic foot ulcer through pre-defined research progression criteria (participant recruitment and retention, duration of…
- Conditions
- Diabetic Foot Ulcer, Diabetic Foot, Wound Healing Disorder, Ulcer Foot
- Trial name
- NCT05101473
- Testing
- Exercise Therapy
- Where
- Denmark
- Volunteers
- 3 people
- Sponsor
- Holbaek Sygehus
Diabetic Foot, Wound Heal
The Effect of Combined Red and Infrared Lasers on Histopathology Collagen Formation in Diabetic Foot Ulcer
Objective: investigate The effect of combined red and infrared lasers on histopathology collagen formation in diabetic foot ulcer Participants: The forty five patients will assigned randomly into three equal groups, each group…
- Conditions
- Diabetic Foot, Wound Heal, Collagen Diseases
- Trial name
- wounds (NCT05739214)
- Testing
- laser therapy
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetic Foot Infection
Real-World Efficacy and Safety Analysis of Omadacycline for the Treatment of Diabetic Foot Infections and Acute Osteomyelitis
This will be a prospective, open-label, two-center study to assess the safety of omadacycline use in the treatment of hospitalized subjects with moderate to severe DFI with or without Acute osteomyelitis (AOM) who are at a high…
- Trial name
- NCT04714411
- Testing
- Omadacycline
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Methodist Health System
Diabetic Foot Ulcers, Osteomyelitis
UT Southwestern Diabetic Foot Ulcers (DFU) and Osteomyelitis (DFO) Recruitment Database, Data and Tissue Repository
This will be a continuing, prospective study of diabetic foot ulcers and infections, risk factors and clinical outcomes and a limited data set conducted by the investigator through the establishment of a data and tissue…
- Trial name
- DFUDatabase (NCT02463500)
- Testing
- DFU
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetic Foot
Biomechanical Study and Orthopedic Treatment Prevent in People With Diabetic Foot
Spain is the country with the second-highest rate of population amputation due to the development of ulcers, behind the United States, where 2 out of 3 non-traumatic amputations derive from diabetes.
- Trial name
- FOOTprevent (NCT04795271)
- Testing
- Orthopedic intervention
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Valencia
Diabetic Foot, Foot Ulcer; Diabetic
Study of Amniotic Membrane Graft in the Management of Diabetic Foot Ulcers
This is comparison trial comparing human amniotic membrane to standard wound care for non healing diabetic foot wounds over a 12 weeks period
- Trial name
- NCT02399826
- Testing
- Offloading, Dressing Application
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lower Extremity Institute for Research and Therapy
Diabetic Foot Ulcer
Outpatient Nurse Managed Counseling Program for Patients With Diabetic Foot Ulceration: a Pilot Study
The purpose of the study is to evaluate the feasibility and effectiveness of a physician directed nurse managed earlier outpatient counselling intervention for patients with diabetic foot ulceration.
- Trial name
- NCT01731808
- Testing
- Nursing counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 19 people
- Sponsor
- Zurich University of Applied Sciences
Diabetes Mellitus, Neuropathic Pain
A Study of Intra-dermal Injection of Botulinum Toxin Type A for the Diabetic Neuropathic Foot Pain
Effective treatment of neuropathic foot pain in diabetic patients is very important to improve their quality of life. There are many medications used to reduce the diabetic neuropathic pain, including anticonvulsants…
- Trial name
- NCT00336349
- Testing
- Botulinum Toxin Type A
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University Hospital
Primary Health Care, Diabetes
Improvement of Diabetic Foot Care in Salamanca Through the Implementation of Standardized Protocols.
Introduction: Diabetic foot (DF) is among the most prevalent complications affecting individuals with diabetes. In Salamanca, 25,631 individuals are enrolled in the Diabetes Care Service, with only 3.06% undergoing a foot…
- Conditions
- Primary Health Care, Diabetes, Diabetic Foot
- Trial name
- NCT06250049
- Testing
- Diabetic foot care protocol, Group education sessions for patients and/or caregivers
- Where
- Spain
- Volunteers
- 25,631 people, healthy volunteers welcome
- Sponsor
- Sanidad de Castilla y León
Diabetic Foot, Diabetic Foot Ulcer
Shear Load In-shoe Plantar Sensing/Strain Analyses and Mapping in Diabetic Foot Ulcers
Stain Analysis Mapping of the Plantar surface (STAMP) is a method designed by the University of Leeds to measure 'in-shoe' strain patterns on the plantar surface of the foot.
- Trial name
- SLIPSTREAM (NCT05687643)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Diabetic Foot Ulcer
The Effect of Exercise on Wound Healing While Off-loading
This study seeks to establish the effect of adding exercise to off-loading interventions on the healing time for people with diabetes mellitus and a foot ulcer.
- Trial name
- NCT04280016
- Testing
- Exercise
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mercer University
Diabetes Mellitus, Critical Limb Ischemia
Laboratory, Cellular and Molecular Determinants of Clinical Success in Diabetic Patients With Critical Limb Ischemia
The ECAD-CLI is an investigator-driven, prospective, single-center study. The aim of the study is to prospectively collect clinical, laboratory, angiographic, cellular and molecular variables related to prognosis and outcome in…
- Conditions
- Diabetes Mellitus, Critical Limb Ischemia, Critical Lower Limb Ischemia, Diabetic Foot
- Trial name
- ECAD-CLI (NCT03636867)
- Testing
- data and specimen collection
- Where
- Italy
- Volunteers
- 236 people
- Sponsor
- Maria Cecilia Hospital
Diabetic Foot Ulcers, Pressure Ulcers
Evaluation of the Effects of HP828-101 Versus Standard of Care in the Management of Partial or Full Thickness Wounds
To compare HP828-101 to standard of care for the management of partial or full thickness wounds
- Trial name
- NCT00971048
- Testing
- HP828-101, Hydrogel/Hydrocolloid
- Where
- 11 sites in United States
- Volunteers
- 88 people
- Sponsor
- Healthpoint
Diabetic Foot Ulcers
Phase III Study to Evaluate Efficacy and Safety of DSC127 in Diabetic Foot Ulcers
The purpose of the study is to determine if DSC127 is effective in increasing incidence of complete wound closure at 10 weeks confirmed at a visit 2 weeks later when compared to the vehicle (gel without active ingredient) in…
- Trial name
- STRIDE 1 (NCT01830348)
- Testing
- DSC127
- Where
- 25 sites in United States
- Volunteers
- 266 people
- Sponsor
- Integra LifeSciences Corporation
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