Clinical trials: Diabetic Feet
Diabetic Peripheral Neuropathy
The Effect of Hand and Foot Exercises Combined With Cold Application or Virtual Reality on Diabetic Neuropathy
The study will be conducted to determine the effect of cold application and virtual reality (VR) or combined hand and foot exercises on pain intensity, kinesiophobia, and fragility levels in patients with diabetic peripheral…
- Trial name
- NCT07085130
- Testing
- Exercises and cold application, Exercises and virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Sakarya University
Diabetic Foot Ulcer
Bioactive Smart Dressings for Diabetic Foot Ulcers: Randomized Controlled Trial
We propose a randomized controlled study to assess the efficacy of: 1. Platelet-lysate loaded sustained release thermo-gelling formulation (Platelets-SR) 2.
- Trial name
- NCT05671250
- Testing
- PRP gel and SOC-treatment, EPO/ISDN/UFH cryogel dressing, Standard of Care
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Diabetic Foot Ulcer
Comparison Between the Effect of Ultrasound Debridement and Conventional Treatment in Diabetic Foot Ulcers (DFU).
The investigators aimed to elucidate the effects of ultrasound debridement on the area and healing of diabetic foot ulcers compared to their conventional treatment.
- Trial name
- NCT04716790
- Testing
- Ultrasound Debridement, Conventional Treatment
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad Complutense de Madrid
Diabetic Foot Ulcer, Hammer Toe
Treatment of Ulcers Associated With Hammer, Mallet and Claw Toe Deformities in the Diabetic Patient Setting
1. Aim Patients with diabetes, hammer, mallet and claw toes and ulcers associated with the named deformities will be randomized to tenotomy (cutting) of flexor tendons to the afflicted toes, done by needle and standard offloading…
- Conditions
- Diabetic Foot Ulcer, Hammer Toe, Mallet Toe, Claw Toe
- Trial name
- TODDII (NCT04154020)
- Testing
- Flexor tenotomy
- Where
- 3 sites in Denmark
- Volunteers
- 21 people
- Sponsor
- Steno Diabetes Center Copenhagen
Diabetic Foot Ulcer
The Use of Allogenic Platelet Rich Plasma for the Treatment of Diabetic Foot Ulcer
Allogenic defibrinated platelet rich plasma lysate will be injected in patients diagnosed with Diabetic Foot Ulcer (DFU).
- Trial name
- NCT02972528
- Testing
- Platelet Lysate, Platelet Poor Plasma
- Where
- Jordan
- Volunteers
- 30 people
- Sponsor
- Hanan Jafar
Diabetic Foot, Health Behavior
Manipulating Narrative Presentations of Information to Encourage Good Foot Care Practice in People With and Without Diabetes Mellitus
The study explores the role of health messages (narrative, non-narrative vs. control condition [no message]) to enhance good foot care practices among people with diabetes and the general population.
- Conditions
- Diabetic Foot, Health Behavior, Foot Diseases
- Trial name
- NCT04623151
- Testing
- Online leaflet about foot care
- Where
- United Kingdom
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- University of Chichester
Diabete Type 2, Diabetic Foot
Prevalence of the Appearance of Diabetic Ulcers in Patients With 3D Insole and LSCI.
Diabetes is a serious and chronic disease that affects more than 347 million people in the world. It is the leading cause of death by age and its prevalence is increasing annually throughout the world.
- Conditions
- Diabete Type 2, Diabetic Foot, Neuropathy, Diabetic, Vascular Disease, Peripheral
- Trial name
- MYFOOT-C (NCT05843929)
- Testing
- LSCI
- Volunteers
- 86 people
- Sponsor
- Esther Soler
Diabetic Peripheral Neuropathic Pain
Using Cannabidiol to Treat Diabetic Peripheral Neuropathy of the Feet
The purpose of the study is to evaluate whether PG-DN-20WS is a better pain reliever in patients with diabetic neuropathic pain of the feet than a placebo.
- Trial name
- NCT04679545
- Testing
- CBD
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Pure Green
Diabetic Foot
A Sympathetic Ganglion, High-voltage Pulsed Radiofrequency Ablation of Peripheral Neuralgia
The Sham Operation Group was used as control, the patients were assessed with the Digital Rating Scale (NRS) , the quality of life-related scale (Euro Qol) , clinical outcome measures: physician's overall impression of changes in…
- Trial name
- NCT05831059
- Testing
- Pulsed radio frequency therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Peripheral Arterial Disease, Critical Limb-Threatening Ischemia
Peripheral Extreme Revascularization in "No-option" Patiens With Chronic Limb Threatening Ischemia
The objective of the study is to evaluate early safety and effectiveness of the percutaneous deep foot venous arterialization performed in clinical practice, in an unselected population of patients with "no-option" CLTI.
- Conditions
- Peripheral Arterial Disease, Critical Limb-Threatening Ischemia, Diabetic Foot
- Trial name
- PiPER (NCT06277362)
- Where
- 9 sites in Italy
- Volunteers
- 50 people
- Sponsor
- EndoCore Lab s.r.l.
Diabetic Foot Ulcer
Spatial Frequency Domain Imaging (SFD) for Assessment of Diabetic Foot Ulcer Development and Healing
This study is designed to evaluate the ability of Spatial Frequency Domain Imaging (SFDI) to measure perfusion in lower extremities for prediction of both healing and formation of diabetic foot ulcers.
- Trial name
- NCT03341559
- Testing
- Spatial Frequency Domain Imaging (SFDI)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Southern California
Diabetic Foot, Lower Limb Wound
Diabetic Foot Care and Limb Preservation Pathway: Developmental Evaluation Study
University Health Network (UHN), working together with local primary care practitioners, patients, and community healthcare services is developing a Diabetic Foot Care and Limb Preservation Care pathway.
- Conditions
- Diabetic Foot, Lower Limb Wound, Diabetes, Amputation
- Trial name
- NCT05446337
- Testing
- Open-Ended Semi-Structured Interview
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Diabetic Foot Ulcer
Intermittent Negative Pressure for Patients With Diabetic Foot Ulcers (INPRESS) Study
The aim of this trial is to investigate the safety and efficacy of 12 weeks treatment with FlowOx, for 1 hour twice daily, when used on patients with diabetic foot ulcers.
- Trial name
- INPRESS (NCT07291817)
- Testing
- FlowOx
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Lo Zhiwen Joseph
Diabetic Foot Infection
Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers
The purpose of this study is to establish the clinical superiority and the safety of topical pexiganan cream 0.8% plus standard local wound care as compared to placebo cream plus standard local wound care, in the treatment of…
- Trial name
- OneStep-2 (NCT01594762)
- Testing
- Topical pexiganan cream 0.8%, Standard wound care
- Where
- 39 sites in United States
- Volunteers
- 200 people
- Sponsor
- Dipexium Pharmaceuticals, Inc.
Diabetic Mellitus, Laser
Helium-Neon Laser Therapy Versus Infrared Laser Therapy in Treating Patients With Diabetic Foot Ulcer
Background: Diabetic patients are frequently showed with foot ulceration as a common complication which increases to 20% in admission.
- Trial name
- NCT03338517
- Testing
- Helium Neon Laser
- Volunteers
- 65 people
- Sponsor
- Ahlia University
Diabetic Foot Ulcer
High Tone External Muscle Stimulation on Diabetic Foot Ulcer
In this study 80 patients will be randomly assigned into two equal groups (40 patients for each group): 1. Group A: Experimental: (high tone external muscle stimulation for diabetic foot ulcer).
- Trial name
- NCT06664723
- Testing
- high tone external muscle stimulation, Standard medical treatment (SMT)
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Diabetic Foot Ulcer
Intensive Glycemic Control For Diabetic Foot Ulcer Healing
With the available molecular and cellular evidence of impaired wound healing due to hyperglycemia, investigators postulate hypothesis asking whether intensive glycemic control could improve diabetic foot ulcer healing rates.
- Trial name
- INGLOBE (NCT04323462)
- Testing
- Insulin Glargine, Diabetic DM
- Where
- 2 sites in India
- Volunteers
- 326 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Diabetic Foot Ulcer, Non-healing Wound
Debritom - Micro Water Jet Technology and Wound Healing
This study will investigate the clinical efficacy of micro water jet technology in the debridement and healing of chronic lower extremity ulcers.
- Conditions
- Diabetic Foot Ulcer, Non-healing Wound, Non-Healing Ulcer of Skin, Venous Leg Ulcer
- Trial name
- NCT04240574
- Testing
- Debritom
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Stephanie Wu
Diabetic Foot, Diabetic Foot Ulcer
Adjunctive Phototherapy Treatment of Infected Diabetic Ulcers
The key purpose of this study is to determine and understand the safety and effectiveness of blue light phototherapy in the treatment and healing of infected diabetic wounds, as well as determining if this treatment is capable of…
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Diabetes, Diabetes Mellitus
- Trial name
- NCT04285710
- Testing
- Phototherapy, Debridement Surgery and Wound Dressing
- Where
- United States
- Sponsor
- Boston Medical Center
Foot Ulcer, Diabetic
Treatment Study of Negative Pressure Wound Therapy for Diabetic Foot Wounds
On behalf of a consortium of 19 health insurance companies the Institute for Research in Operative Medicine as part of the University of Witten / Herdecke gGmbH is planning and conducting a clinical study evaluating the efficacy…
- Trial name
- DiaFu (NCT01480362)
- Testing
- Negative Pressure Wound Therapy, Standard Wound Therapy
- Where
- 42 sites in Germany
- Volunteers
- 360 people
- Sponsor
- University of Witten/Herdecke
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