Clinical trials: Diabetic Feet
Diabetic Foot Ulcer
Intensive Versus Conventional Glycemic Control in Diabetic Foot Ulcer Healing
Diabetic foot ulcer is one of the most serious, most costly and at times life threatening complication of diabetes. The lifetime incidence of foot ulcer occurrence in diabetes is up to 25%.
- Trial name
- InVeCoG:DFU (NCT03740581)
- Testing
- Insulin
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Diabetic Foot Ulcer
Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers
The purpose of this clinical trial is to evaluate the safety and effectiveness of the treatment with the COMS One device in subjects with refractory diabetic foot ulcers (DFUs).
- Trial name
- Mavericks (NCT05758545)
- Testing
- COMS One device
- Where
- 30 sites in United States
- Volunteers
- 450 people
- Sponsor
- Piomic Medical
Diabetic Foot, DFU
Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers
The purpose of this study is to evaluate the efficacy of human placental membrane products and standard of care versus standard of care alone in the management of nonhealing diabetic foot ulcers and venous leg ulcers.
- Conditions
- Diabetic Foot, DFU, Diabetic Foot Ulcer, Foot Ulcer, Diabetic
- Trial name
- BIOCAMP (NCT07089602)
- Testing
- Standard of Care DFU, Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- BioLab Holdings
Diabetic Foot
Evaluate the Efficacy and Safety of ON101 Cream for the Treatment of Chronic Diabetic Foot Ulcers
The primary objective of this study is to evaluate the efficacy of the new treatment of WH-1 ointment compared to Aquacel® Hydrofiber® dressing, applied to chronic diabetic foot ulcers for up to 16 weeks.An additional objective…
- Trial name
- NCT01898923
- Testing
- ON101 Cream, Aquacel® Hydrofiber® dressing
- Where
- 21 sites in United States, China and 1 more
- Volunteers
- 236 people
- Sponsor
- Oneness Biotech Co., Ltd.
Diabetic Neuropathy
Effects of a Homeopathic Anti-inflammatory Topical Cream on Ulcers and Neuropathy in the Diabetic Foot
This is a study whose primary objective is to assess the effectiveness of Neuropathy/Ulcer Cream in the promotion of healing skin fissures plantar foot ulcers and as a moisturizer to prevent dry skin turning into ulcers as…
- Trial name
- NCT01951859
- Testing
- Neuropathy/Ulcer Homeopathic topical cream
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Calvary Hospital, Bronx, NY
Diabetes Mellitus Type 2, Sensory Neuropathy
Evaluation of Pressure Distribution of Kyboot Shoes in Comparison to Other Foot Wear
Comparison and evaluation of pressure distribution, gait pattern, changes in the movement of the center of pressure, shock absorbing capabilities and comfort of wear using KyBoot shoes versus normal foot wear in diabetic and…
- Conditions
- Diabetes Mellitus Type 2, Sensory Neuropathy, Foot Ulcer, Diabetic
- Trial name
- Kyboot (NCT02451722)
- Testing
- Kyboot shoes
- Where
- Israel
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Diabetic Foot Ulcer
Effects of Empowerment-based Program on Post-discharge Glycemic Control, and Foot Ulcer
The purpose of this study is to evaluate an empowerment-based program. A randomized controlled trial design will be used. From August 2019 to July 2021, 160 subjects will be recruited at a medical center and randomly assigned to…
- Trial name
- NCT03993990
- Testing
- individual empowerment-based intervention
- Where
- Taiwan
- Sponsor
- Chin yenfan
Diabetes Mellitus
Insulin Iontophoresis Mixed With Oleic Acid Versus Topical Insulin in Patients With Chronic Diabetic Foot Ulcer
This study will be conducted to investigate the effect of Insulin iontophoresis mixed with oleic acid versus topical insulin in patients with chronic diabetic foot ulcer
- Trial name
- NCT05444842
- Testing
- insulin iontophoresis, topical insulin, conventional treatment
- Volunteers
- 45 people
- Sponsor
- Cairo University
Diabetic Foot Ulcer
Characterization of AmnioExcel Plus in Two Treatment Paradigms
The Investigators plan to evaluate healing in two cohorts of patients with diabetic foot wounds (n=20) that receive optimal treatment including serial wound debridement and off-loading with a boot or postop shoe and AmnioEXCEL+.
- Trial name
- NCT04233580
- Testing
- Amnio Excel + weekly, Amnio Excel + max every 2 weeks
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetic Foot
The Pharmacokinetic Study of WH-1 Ointment in Subjects With Chronic Diabetic Foot Ulcers
The objective of this study is to evaluate the systemic exposures of WH-1 ointment which includes Salvigenin and Asiaticoside A in subjects with chronic diabetic foot ulcers following topical application of WH-1.
- Trial name
- NCT02353273
- Testing
- WH-1 ointment
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Oneness Biotech Co., Ltd.
Diabetic Neuropathy, Painful
A Study for the Treatment of Painful Diabetic Neuropathy
The purpose of the study is to determine if duloxetine can help patients with painful diabetic neuropathy.
- Trial name
- NCT00058968
- Testing
- Duloxetine hydrochloride
- Where
- United States
- Volunteers
- 660 people
- Sponsor
- Eli Lilly and Company
Diabetic Foot, Diabetes Mellitus
The Role of Extrinsic Foot Muscles Chances in Determining the Risk of Diabetic Foot Ulcer
Many foot and lower limb disorders resulting from diabetes, such as deformity, muscle weakness, reduced range of motion, stiffness of connective tissue, amount of oxygenation, functional capacity, poor balance and coordination…
- Trial name
- NCT06736210
- Testing
- Muscle Elastic Properties Measurement, Muscle Oxygen Saturation (SmO2), Plantar Pressure Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Diabetic Foot
Clinical Trial for the Treatment of Diabetic Foot Ulcers Using a Nitric Oxide Releasing Patch: PATHON
Diabetes Mellitus constitutes one of the most important public health problems due to its high prevalence and enormous social and economic consequences.
- Trial name
- NCT00428727
- Testing
- Controlled nitric oxide releasing patch
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Fundación Cardiovascular de Colombia
Skin Lesion, Traumatic Ulcer
Clinical Investigation EUCLIDES-01 for the Calculation of the Area of Skin Lesions
The aim of this clinical investigation is to collect skin lesion area data for the comparison of the agreement among the results obtained between the following three wound area measurement methods: Ruler using the Kundin method…
- Conditions
- Skin Lesion, Traumatic Ulcer, Hematoma, Pressure Ulcer
- Trial name
- NCT05729334
- Testing
- Clinicgram Euclides
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Skilled Skin S.L.
Non-healing Wound, Non-healing Diabetic Foot Ulcer
Phase 2 Pilot Trial of Subjects With Complex Non-healing Diabetic Foot Ulcers Treated With Standard Care Plus Cryopreserved Umbilical Cord Allograft (TTAX01)
It is hypothesized that application of the human placental umbilical cord tissue TTAX01 to the surface of a well debrided, complex diabetic foot ulcer will, with concomitant management of infection, result in a higher proportion…
- Conditions
- Non-healing Wound, Non-healing Diabetic Foot Ulcer, Diabetic Foot Infection
- Trial name
- NCT03230175
- Testing
- TTAX01, Surgical resection and debridement, Systemic antibiotics
- Where
- 11 sites in United States
- Volunteers
- 32 people
- Sponsor
- BioTissue Holdings, Inc
Diabetic Foot Ulcer Healing Trajectories
Efficacy of Negative Pressure Wound Therapy Versus Conventional Moist Dressings on Diabetic Foot Ulcer Healing Trajectories
Background: Diabetic foot ulcers (DFUs) are severe, chronic complications of diabetes carrying a high risk of amputation. While Negative Pressure Wound Therapy (NPWT) is an active biophysical treatment, clinical evidence using…
- Trial name
- DF-WOUND-RCT (NCT07745075)
- Testing
- Vacuum-Assisted Closure (VAC / NPWT)
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jerash Private University
Diabetic Foot Ulcer
Affinity Prospective Diabetic Foot Trial Crossover Group
This study is an extension of the randomized controlled trial NT-DFU-AFF-01. Subjects that were randomized to the Standard of Care group will be able to crossover to the NT-DFU-AFF-02 trial and receive Affinity fHSAM if certain…
- Trial name
- NCT03205436
- Testing
- Affinity human amniotic membrane
- Where
- 6 sites in United States
- Volunteers
- 20 people
- Sponsor
- Organogenesis
Chronic Diabetic Foot Ulcer
Fespixon Cream for the Treatment of Chronic Diabetic Foot Ulcers (TEXAS 1A, 2A) in Dialysis Patients
Evaluate the Safety and Efficacy of Fespixon Cream for the Treatment of Chronic Diabetic Foot Ulcers (TEXAS 1A, 2A) in dialysis patients This study aimed to evaluate the effects of a topical cream containing Plectranthus…
- Trial name
- NCT05338463
- Testing
- Fespixon Cream
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- Cathay General Hospital
Diabete Type 2
Risk Factors for Developing Peak Plantar Pressure During Walking in the Diabetic Patients
The goal of this observational study is to investigate the clinically convenient dynamic and static measurement parameters to identify related risk factors of developing high peak plantar pressure during walking in the type-2…
- Trial name
- NCT07164495
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Diabetic Neuropathies
Effects of Foot Muscle Strengthening in Daily Activity in Diabetic Neuropathic Patients
The main objective of this trial is to investigate the effects of foot muscle strengthening in daily activity of patients with diabetic neuropathy.
- Trial name
- NCT02790931
- Testing
- Intervention Group
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- University of Sao Paulo General Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.