Clinical trials: Diabetic Ketoacidosis
Diabetic Ketoacidosis
Serum Ferritin and Prognosis of DKA
the aim of this study is to: evaluate the association between serum ferritin levels and the clinical presentation and short-term prognosis of patients with DKA.
- Trial name
- NCT06748365
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Sepsis, Acute Kidney Injury
Identifying Risk Factors for Developing AKI in Sepsis
A study to evaluate the prevalence of Acute Kidney Injury (AKI) in patients with Diabetic Ketoacidosis (DKA) and sepsis using data collected prospectively to a patient registry.
- Conditions
- Sepsis, Acute Kidney Injury, Diabetic Ketoacidosis
- Trial name
- NCT04825639
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Cardiff and Vale University Health Board
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Diabetic Ketoacidosis
Intravenous Fluids in Adults With Diabetic Ketoacidosis in the Emergency Department
Diabetes mellitus is a common chronic disease. It is estimated that up to 40% of adults may develop diabetes in their lifetime. Patients with poorly controlled blood sugars often visit the emergency department for treatment of…
- Trial name
- BRISK-ED (NCT04926740)
- Testing
- Ringer's lactate
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
AKI in Diabetic Ketoacidosis
Prevalence of Acute Kidney Injury in Patients With Diabetic Ketoacidosis
prevalence of acute kidney injury in patients with diabetic ketoacidosis
- Trial name
- NCT05508490
- Testing
- renal chemistry, serum electrolyte,
- Volunteers
- 100 people
- Sponsor
- Assiut University
Diabetic Ketoacidosis
Children with Diabetic Ketoacidosis
In the present work we aim to 1. Response to therapy, During the management of DKA, acid base status, glycemia, and serum electrolytes are measured frequently to monitor the efficacy of treatment, detect complications of DKA and…
- Trial name
- NCT06599203
- Volunteers
- 130 people
- Sponsor
- Assiut University
Diabetes Mellitus, Diabetes Mellitus, Type 1
RT-CGM in Young Adults at Risk of DKA
Pilot study to evaluate the effect of real time continuous glucose monitoring (RT-CGM) on young-adults with insulin-treated diabetes, who are defined as high risk due to suboptimal HbA1c (blood glucose control) or a history of…
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 1, Glucose Metabolism Disorders, Metabolic Disease
- Trial name
- YODA (NCT04039763)
- Testing
- Dexcom G6, Self monitoring of blood glucose
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College London
Diabetic Ketoacidosis, Type 1 Diabetes
Early Basal Insulin Administration in Adult Diabetic Ketoacidosis Management
Early Basal Insulin Administration in Adult Diabetic Ketoacidosis Management
- Conditions
- Diabetic Ketoacidosis, Type 1 Diabetes, Type 2 Diabetes
- Trial name
- NCT04567225
- Testing
- Early Glargine, Late Glargine, IV insulin infusion
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- The Cleveland Clinic
Diabetic Ketoacidosis, Diabetes Mellitus
Leukocyte Glucose Index and Severity of Diabetic Ketoacidosis
This prospective cohort study aims to evaluate the relationship between admission Leukocyte Glucose Index (LGI) and the severity of diabetic ketoacidosis, as well as the presence of diabetic microvascular complications, among…
- Trial name
- NCT07821814
- Volunteers
- 120 people
- Sponsor
- Assiut University
Type 1 Diabetes
Evaluating the Occurrence of DKA in People With Type I Diabetes
This study will evaluate the occurrences of Diabetes-related Ketoacidosis (DKA) in adult and pediatric individuals living with Type I diabetes while managing diabetes with Abbott's Continuous Monitoring Systems.
- Trial name
- NCT07739342
- Testing
- Abbott Continuous Dual Glucose Ketone Monitoring System
- Where
- 7 sites in New Zealand
- Volunteers
- 1,200 people
- Sponsor
- Abbott Diabetes Care
Drug Overdose, Metformin
Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning
This study looks at patients admitted to intensive care for drug poisoning involving metformin, a common diabetes medication. Researchers will compare two groups: patients who overdosed on metformin alone and those who took both…
- Conditions
- Drug Overdose, Metformin, Dapagliflozin, Lactic Acidosis
- Trial name
- NCT07193069
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Chronic Kidney Diseases
Outcome of Glargine Insulin in Renal Impairment Patients With Diabetic Ketoacidosis
The study aims to compare between the use of continuous low dose insulin infusion versus co-administration of low dose continuous insulin infusion and early subcutaneous insulin glargine in diabetic ketoacidosis patients with…
- Trial name
- NCT05219942
- Testing
- Glargine, normal saline
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Cerebral Edema, Diabetic Ketoacidosis
Randomized Control Trial of Fluid Therapy for Pediatric Diabetic Ketoacidosis
The investigators will conduct a randomized controlled trial comparing four different intravenous (IV) fluid treatment protocols for pediatric diabetic ketoacidosis (DKA).
- Trial name
- NCT01365793
- Testing
- 0.45% saline replacement fluid, 0.9% saline replacement fluid, 0.45% saline intravenous fluid
- Where
- 13 sites in United States
- Volunteers
- 1,389 people
- Sponsor
- University of California, Davis
Diabetic Ketoacidosis
Basal Insulin in the Management of Patients With Diabetic Ketoacidosis (DKA)
The study is a multicenter, randomized controlled trial to compare the safety and efficacy of insulin analogs and human insulins both during acute intravenous treatment and during the transition to subcutaneous insulin in…
- Trial name
- NCT00590044
- Testing
- insulin glargine+ glulisine, NPH + Regular insulin
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- Emory University
Type 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM)
Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring.
The goal of this clinical trial is to develop and evaluate a novel diabetes ketoacidosis risk mitigation strategy to support the safe use of sodium-glucose cotransporter-2 inhibitors (SGLT2i) therapy in participants with type 1…
- Conditions
- Type 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM), Chronic Kidney Disease, Diabetic Ketoacidosis
- Trial name
- SCOUT-CKD (NCT07325201)
- Testing
- Sotagliflozin initiation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- HealthPartners Institute
Diabetes Mellitus, Ketosis, Diabetic
StatStrip Glucose/Ketone Meter System Ketone Evaluation
The Nova StatStrip Glucose / Ketone Meter System is a fast, simple, whole blood system that can be used to quantify both glucose and ketones using two distinct test strips.
- Trial name
- NCT05118061
- Testing
- Ketone
- Where
- 3 sites in United States, Germany
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Nova Biomedical
Diabetic Ketoacidosis, Type 1 Diabetes Mellitus
Early Glargine (Lantus) in DKA Management in Children With Type 1 Diabetes
A frequent complication in the management of diabetic ketoacidosis (DKA) in children with type 1 diabetes is rebound hyperglycemia (blood glucose over 180 mg/dL) which increases the risk of re-developing DKA and can lengthen the…
- Trial name
- NCT03107208
- Testing
- Glargine, Continuous Glucose Monitor (Abbott FreeStyle Libre Pro)
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Diabetic Ketoacidosis
Two Bag System for Diabetic Ketoacidosis
This is a study investigating the best way to treat diabetic ketoacidosis (DKA) with intravenous (IV) fluids in the hospital. The purpose of this study is to determine whether the "two bag" system of administering IV fluids for…
- Trial name
- 2BagDKA (NCT03660189)
- Testing
- Two bag system
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- MetroHealth Medical Center
Diabetes Mellitus, Type 2
Post-authorisation Safety Study in Patients With Type 2 Diabetes to Assess the Risk of Liver Injury, Kidney Injury, Urinary Tract and Genital Infections, and Diabetic Ketoacidosis in Patients Treated With Empagliflozin, Compared to DPP-4 Inhibitors
Empagliflozin (Jardiance), a highly potent and selective inhibitor of the sodium-glucose cotransporter 2 (SGLT2), was approved in Europe in May 2014 for the treatment of type 2 diabetes mellitus (T2DM) to improve glycaemic…
- Trial name
- NCT02864914
- Testing
- Empagliflozin, DPP-4 inhibitors
- Where
- United Kingdom
- Volunteers
- 333,580 people
- Sponsor
- Boehringer Ingelheim
DKA
Early Administration of Insulin Glargine in Patients With Diabetic Ketoacidosis
Diabetic ketoacidosis (DKA) is a medical emergency that is associated with significant morbidity and mortality for both patients with type I and type II diabetes.
- Trial name
- NCT06007508
- Testing
- Insulin Glargine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- HealthPartners Institute