Clinical trials: Diabetic Neuropathy Peripheral
Diabetic Peripheral Neuropathy
The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy
The goal of this observational study is to explore the relationship between related blood indicators and diabetic peripheral neuropathy.
- Trial name
- NCT06041399
- Testing
- hypoglycemic Agents(metformin), lipid-lowering drug(Statin)
- Where
- China
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Diabetes Mellitus, Diabetic Neuropathy
Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
- Trial name
- ANKLE-DM (NCT07404124)
- Testing
- Ultrasound-Guided Ankle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Diabetes Mellitus Type 2
MOE and DNSE Effects on Balance and Activities of Daily Living Diabetic Peripheral Neuropathy
The purpose of this study is to compare the impact of Modified Otago Exercises and Dynamic Neuromuscular Stabilization Exercises on patients with diabetic peripheral neuropathy (DPN) using valid tools such as the Berg Balance…
- Trial name
- NCT07293507
- Testing
- Modified Otago Exercises, Dynamic neuromuscular stabilization exercises
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Oxidative Stress, Diabetic Polyneuropathy
Statins for Oxidative Stress and Mitochondrial Function in Diabetic Polyneuropathy
Aims: To evaluate the effect of ezetimibe/simvastatin and rosuvastatin on oxidative stress and mitochondrial function in patients with DPN.
- Trial name
- NCT02129231
- Testing
- calcined magnesia, Ezetimibe/simvastatin, Rosuvastatin
- Where
- Mexico
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Diabetic Neuropathy, Neuropathic Pain
Pain In Neuropathy Study
In the context of peripheral neuropathy, we will aim to elucidate correlates between sensory symptoms and: Sensory nerve dysfunction. Cutaneous small nerve fibre innervation density. Psychological co-morbidity.
- Conditions
- Diabetic Neuropathy, Neuropathic Pain, Chronic Pain, Carpal Tunnel Syndrome
- Trial name
- PINS (NCT02672059)
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- King's College London
Diabetes Type 1, Proteomics
Proteomic Analysis in Paediatric Diabetes Type 1 (PAPD)
The aim of the present study is to investigate a targeted proteomic analysis in plasma of children - of Greek origin- with type 1 diabetes (DT1) and its correlation with the electrophysiological findings that accompany diabetic…
- Conditions
- Diabetes Type 1, Proteomics, Diabetic Peripheral Neuropathy
- Trial name
- PAPD (NCT04257877)
- Testing
- Blood sampling
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Diabetic Foot
Validation of Ipswich Touch Test for Diabetic Peripheral Neuropathy Screening in Primary Care
The goal of this observational study is to assess the accuracy of screening for diabetic peripheral neuropathy by comparing the Ipswich touch test with the 10-g monofilament test in patients diagnosed with type 2 diabetes.
- Trial name
- NCT06288555
- Testing
- Ipswich touch test
- Where
- Thailand
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Ponlawat Hanchana, MD
Diabetes Mellitus, Type 2, Diabetic Polyneuropathy
Use of GDF15 as a Biomarker for Early Diagnosis of DM and Monitoring of Progress of Complications in Asians
Significant differences in the expression of individual Growth Differentiation Factor 15 (GDF-15) proteins among Taiwanese harboring different mitochondrial genotypes are noted, and their blood serum levels also exhibited…
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Polyneuropathy, Diabetic Nephropathies
- Trial name
- NCT04119167
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Diabetic Peripheral Neuropathy
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Food Effect of SYHA1402 in Healthy Subjects
A Multiple Doses Study to Evaluate the Safety, Tolerability, Pharmacokinetics (Including Food Effect) of SYHA1402 in Healthy Subjects.
- Trial name
- NCT04453618
- Testing
- FE-SYHA1402 100mg, SYHA1402-25mg, SYHA1402-50mg
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Diabetic Polyneuropathy, Healthy Individuals (Controls)
PULP SENSIBILITY AND MASSETER INHIBITORY REFLEX IN DIABETIC POLYNEUROPATHY
Accurate evaluation of dental pulp health is essential to avoid unnecessary endodontic treatments. In routine dental practice, pulp sensibility is commonly assessed using electric pulp testing and thermal (cold) testing.
- Trial name
- NCT07369297
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Diabetes Mellitus, Peripheral Neuropathy
Diabetes Peripheral Neuropathy and Small-fibre Nerve Damage: A Comparative Study
The purpose of this study is to investigate whether patients with diabetes-related peripheral neuropathic pain also have non-recognized damage to the intestine caused by autonomic neuropathy.
- Conditions
- Diabetes Mellitus, Peripheral Neuropathy, Small Fibre Neuropathy, Autonomic Neuropathy
- Trial name
- NCT01160887
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Neuralgia, Neuralgia; Postherpetic
Evaluation of an Effectiveness and Safety of the Electroacupuncture in the Management of Intractable Neuropathic Pain
The investigators will evaluate the effectiveness and safety of acupuncture treatment in refractory neuropathic pain patients.
- Conditions
- Neuralgia, Neuralgia; Postherpetic, Diabetic Neuropathy, Painful, Failed Back Surgery Syndrome
- Trial name
- NCT03315598
- Testing
- Electroacupuncture
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Diabetes Mellitus, Type 2, Polyneuropathy Diabetes
Resistance Training in Patients With Diabetic Neuropathy
This is a population-based study of type 2 diabetes patients with and without neuropathy recruited from the Danish National Type 2 Diabetes cohort (DD2).
- Conditions
- Diabetes Mellitus, Type 2, Polyneuropathy Diabetes, Diabetes Complications, Diabetic Peripheral Neuropathy
- Trial name
- NCT03252132
- Testing
- 12-week resistance training
- Where
- Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Danish Pain Research Center
Peripheral Neuropathy, Autonomic Neuropathy
Autonomic Nervous System Dysfunction and Peripheral Neuropathy in a Cohort of Asymptomatic Juvenile Diabetic Patients (Type I): A Case-Controlled Study
This is a case-controlled study using an innovative, non-invasive, FDA approved technology to measure the autonomic nervous system.
- Trial name
- NCT00466778
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Weintraub, Michael I., MD, FACP, FAAN
Diabetic Peripheral Neuropathy
In Vivo Corneal Confocal Microscopy for Non-invasive Assessment of Diabetic Peripheral Neuropathy
Clinical in vivo confocal microscopy (IVCM) is a relatively new technique of corneal evaluation that permits non-invasive imaging of corneal structures on the cellular level.
- Trial name
- NCT01695629
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Low Back Pain, Diabetic Peripheral Neuropathy
MR(Magnetic Resonance) Imaging of Neurotransmitters in Chronic Pain
This study is designed to assess: Hypothesis #1: That there is a significant central pain component in a distinct subset of patients diagnosed with knee osteoarthritis(KOA), Chronic low back pain(CLBP), painful diabetic…
- Conditions
- Chronic Low Back Pain, Diabetic Peripheral Neuropathy, Knee Osteoarthritis
- Trial name
- NCT01620775
- Testing
- MRIs, Pain testing
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Neuropathy, Neuropathy, Painful
MultiSENSory Stimulation to TArgeT Sensory Loss and ChronIc Pain in NeurOpathic PatieNts
Neuropathy is a costly and disabling health issue, which consists of a degeneration of the peripheral nerves. Even though the causes may be different, such as diabetes or amputation, the consequences for neuropathic patients are…
- Conditions
- Neuropathy, Neuropathy, Painful, Sensory Neuropathy, Diabetic Neuropathies
- Trial name
- SENSATION (NCT05483816)
- Testing
- VR+TENS
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Diabetic Peripheral Neuropathy (DPN)
Administrative Claims Analysis of Metanx® in Diabetic Peripheral Neuropathy
This study will be an observational cohort study utilizing administrative claims data with 100 patients randomly selected taking Metanx® meeting the inclusion and exclusion criteria and 400 propensity score matched patients…
- Trial name
- NCT01247558
- Testing
- Metanx® (a medical food), Not treated with Metanx®
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Pamlab, L.L.C.
Diabetes Mellitus, Type 1, Diabetic Cardiomyopathies
Preclinical Cardiomyopathy and Autonomic Function in Type 1 Diabetes
Type 1 diabetes mellitus is a chronic autoimmune disease, associated with an increased risk of cardiovascular diseases. The development of cardiomyopathy in type 1 diabetes, independent of hypertension and coronary heart disease…
- Conditions
- Diabetes Mellitus, Type 1, Diabetic Cardiomyopathies, Autonomic Neuropathy, Diabetic
- Trial name
- NCT03930004
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Roberto Léo da Silva
Diabetic Neuropathies
Corneal Confocal Microscopy in Patients With Type 1 Diabetes
Assessing the use of corneal confocal microscopy to evaluate for early neuropathy changes in subjects with Type 1 Diabetes.
- Trial name
- CCM (NCT03045250)
- Testing
- Corneal confocal microscopy, Skin biopsy, Nerve conduction study
- Volunteers
- healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine