Clinical trials: Diabetic Peripheral Neuropathy (DPN)
Diabetic Neuropathies
Pain Diabetic Peripheral Neuropathy（DPN) in China
To understand the clinical characteristics of DPN patients in China; To investigate the distribution of DPN patients with depression and anxiety symptoms; To investigate the related factors of moderate and severe pain in DPN…
- Trial name
- NCT04456465
- Testing
- Pain diabetic peripheral neuropathy
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Peking University Third Hospital
Neuropathic Pain
Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults
The goal of this clinical trial is to learn if ASCT-83 is safe and well-tolerated and measure how ASCT-83 is absorbed, distributed, and eliminated from the body over time. The study will be conducted in healthy adults.
- Trial name
- NCT07363395
- Testing
- ASCT-83
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Alcamena Stem Cell Therapeutics
Diabetic Peripheral Neuropathic Pain (DPN)
NDS and NSS for Screening Diabetic Neuropathy
Diabetic sensorimotor polyneuropathy is a common complication of diabetes mellitus that can lead to pain, sensory loss, foot ulcers, and disability.
- Trial name
- NCT07557641
- Where
- Thailand
- Volunteers
- 228 people
- Sponsor
- Chulalongkorn University
Pain
[S,S]-Reboxetine Long Term Safety Study In Chronic Painful Diabetic Peripheral Neuropathy.
The purpose of this study is to assess the long-term safety and tolerability of [S,S]-Reboxetine in patients with chronic painful diabetic peripheral neuropathy
- Trial name
- NCT00348894
- Testing
- [S,S]-Reboxetine, Any
- Where
- 93 sites in United States, Argentina and 12 more
- Volunteers
- 136 people
- Sponsor
- Pfizer
Diabetic Peripheral Neuropathic Pain (DPN)
Effect of Trimetazidine on Endothelin-1 and Clinical Outcomes of Patients With Diabetic Peripheral Neuropathy
The goal of this clinical trial is to investigate if trimetazidine can improve clinical outcomes of patients with diabetic peripheral neuropathy.
- Trial name
- NCT07794475
- Testing
- Trimetazidine Dihydrochloride Tablets
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sara Refaat Azab Metry
Diabetic Peripheral Neuropathy (DPN)
Clinical Study of Zuogui Jiangtang Shuluo Formula in Treating Diabetic Peripheral Neuropathy
Diabetic peripheral neuropathy (DPN) is a common complication of type 2 diabetes mellitus, affecting 35%-50% of diabetic patients.
- Trial name
- NCT07771894
- Testing
- Zuogui Jiangtang Shuluo Formula, Mecobalamin
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Diabetic Peripheral Neuropathy (DPN)
A Randomized Controlled Trial on the Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cell Therapy in Subjects With Moderate to Severe Diabetic Peripheral Neuropathy
This clinical trial aims to evaluate the efficacy and safety of human umbilical cord mesenchymal stem cell (hUC-MSC) injection in the treatment of adults with moderate to severe diabetic peripheral neuropathy.
- Trial name
- RELEASE-DPN (NCT07183761)
- Testing
- Experimental Group, Conventional therapy group
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Min Long
Diabetic Peripheral Neuropathy, Balance
Effects of Virtual Reality-Based Balance Training Compared to Conventional Balance Training to Reduce Risk of Fall in Patients With Diabetic Peripheral Neuropathy: A Randomized Control Trial
The objective of this study is to determine the effects of virtual reality based balance training compared to conventional balance training to reduce risk of fall in patients with diabetic peripheral neuropathy in terms of fall…
- Conditions
- Diabetic Peripheral Neuropathy, Balance, Fall Risk
- Trial name
- NCT06740227
- Testing
- Virtual Reality-Based Balance Training, Conventional Balance Training
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
Diabetic Peripheral Neuropathic Pain (DPN)
Hyperbaric Oxygen Therapy Versus High Power Laser for Diabetic Neuropathy
The purpose of this study is to compare the clinical effects of Hyperbaric Oxygen Therapy (HBOT) versus High-Intensity Laser Therapy (HPLT) on sensorimotor functions and nerve conduction in patients suffering from painful…
- Trial name
- HBOT-HPLT-DPN (NCT07848867)
- Testing
- Conventional Physiotherapy Program, Hyperbaric Oxygen Therapy, High-Intensity Laser Therapy
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Diabetic Peripheral Neuropathy
Efficacy and Safety Study of Pregabalin in the Treatment of Pain on Walking in Patients With Diabetic Peripheral Neuropathy (DPN)
The intent of this study is to treat subjects with painful Diabetic Peripheral Neuropathy (DPN) who also have pain on walking and to determine whether or not pregabalin demonstrates improvement relative to placebo on the…
- Trial name
- NCT01474772
- Testing
- Pregabalin
- Where
- 45 sites in United States, Czechia and 2 more
- Volunteers
- 217 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Diabetic Peripheral Neuropathy (DPN)
Ultrasound Assessment of Sciatic Nerve and Inferior Gluteal Artery in Diabetic Peripheral Neuropathy(DPN): Association With a Target Gene
Diabetic peripheral neuropathy (DPN) is a common and serious complication of diabetes that causes numbness, pain, and weakness, often starting in the feet.
- Trial name
- NCT07595887
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Hospital of Shanxi Medical University
Diabetic Peripheral Neuropathy
Restoration of Cutaneous Sensorum in Patients With Diabetic Peripheral Neuropathy (DPN) Via Metanx®
The purpose of this research study is to determine if Metanx improves sensory neuropathy in persons with Type 2 diabetes. Metanx is a medical food available with a prescription from a physician.
- Trial name
- NCT00933998
- Testing
- Metanx® (Oral L-methylfolate, Methylcobalamin and Pyridoxal 5'-phosphate)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carolina Musculoskeletal Institute
Exercise Addiction, Diabetic Neuropathies
Effects of Aerobic Thai Dance in Patient With Diabetic Peripheral Neuropathy
The goal of this type of study is clinical trial. This to learn about effects of applied aerobic Thai dance exercise on gait balance and sudomotor function in patient with diabetic peripheral neuropathy.
- Trial name
- NCT06061237
- Testing
- Aerobic Thai dance exercise
- Where
- Thailand
- Volunteers
- 44 people
- Sponsor
- Chulalongkorn University
Neuropathy, Diabetic
A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN)
The purpose of this study is to determine whether gabapentin enacarbil (XP13512/GSK1838262), hereafter referred to as GEn is effective in the treatment of neuropathic pain associated with diabetic peripheral neuropathy(DPN)
- Trial name
- NCT00643760
- Testing
- GEn 1200mg/day, GEn 2400mg/day, GEn 3600mg/day
- Where
- 90 sites in United States
- Volunteers
- 421 people
- Sponsor
- XenoPort, Inc.
Diabetic Peripheral Neuropathy (DPN)
Multi-Sensory Training for Balance, EMG, Sensory Deficits in DPN
This study evaluated whether a 12-week multisensory training program could improve movement control, balance, and sensory function in women with diabetic peripheral neuropathy (DPN).
- Trial name
- MST (NCT07096570)
- Testing
- Selected Multisensory Training (SMST)
- Where
- Iran
- Volunteers
- 19 people
- Sponsor
- Monireh Asadi Ghaleni
Diabetic Neuropathy, Painful
A Clinical Trial To Evaluate PF-05089771 On Its Own And As An Add-On Therapy To Pregabalin (Lyrica) For The Treatment Of Pain Due To Diabetic Peripheral Neuropathy (DPN)
The purpose of this study is to evaluate the efficacy and safety of PF-05089771 as a monotherapy and as an add-on to pregabalin for the treatment of painful diabetic peripheral neuropathy (DPN)
- Trial name
- NCT02215252
- Testing
- PF-05089771 150 mg, Pregabalin 300 mg, PF-05089771 150 mg + Pregabalin 300 mg
- Where
- 32 sites in United States
- Volunteers
- 141 people
- Sponsor
- Pfizer
Diabetic Peripheral Neuropathy (DPN)
Far-Infrared Socks for Neuropathic Pain and Nerve Function in Diabetic Patients
This study aims to evaluate the effectiveness of far-infrared radiation (FIR) emitting socks in improving neuropathic pain, nerve conduction, and quality of life in patients with diabetic peripheral neuropathy (DPN).
- Trial name
- FIR-DPN (NCT06880484)
- Testing
- Far-Infrared Radiation (FIR) Socks
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- TC Erciyes University
Painful Diabetic Neuropathy
An Evaluation of an SCCD on the Symptomatology of Painful DPN
This is a controlled trial to evaluate the efficacy of an Sequential Contraction Compression Device (SCCD) on the symptomatology of Painful Diabetic Neuropathy.
- Trial name
- NCT03331614
- Testing
- Flowaid FA-100 SCCD
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Rosenblum, Jonathan I., DPM
Diabetic Peripheral Neuropathy (DPN), Pain
Study on Serum Transcriptomics and Metabolomics in Patients With Diabetic Peripheral Neuropathy
This part of the study enrolled 30 sex- and age-matched healthy controls, 30 diabetic patients without peripheral neuropathy, and 30 patients with diabetic peripheral neuropathy (DPN).
- Trial name
- NCT07518433
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Diabetic Peripheral Neuropathy (DPN)
Administrative Claims Analysis of Metanx® in Diabetic Peripheral Neuropathy
This study will be an observational cohort study utilizing administrative claims data with 100 patients randomly selected taking Metanx® meeting the inclusion and exclusion criteria and 400 propensity score matched patients…
- Trial name
- NCT01247558
- Testing
- Metanx® (a medical food), Not treated with Metanx®
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Pamlab, L.L.C.