Clinical trials: Diabetic Retinal Disease
Diabetic Retinopathy
Anti-inflammatory Effect of Curcumin, Homotaurine, Vitamin D3 on Human Vitreous in Patients With Diabetic Retinopathy
Dosage of pro-inflammatory cytokines and soluble mediators (TNFα, IL6, IL2 and PDGF-AB) performed on 25 vitreous biopsies taken from patients with diabetic retinopathy and treated with increasing doses of curcumin (0.5uM and…
- Trial name
- NCT04378972
- Testing
- curcumin, homotaurine, vitamin D3, control
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- University of Molise
Rubeosis Iridis, Proliferative Diabetic Retinopathy
Use of Ranibizumab to Treat Rubeosis in Diabetics Prior to Cataract Surgery
The purpose of this study was to determine the safety of ranibizumab: a) as a surgical adjunct during cataract surgery in subjects with proliferative diabetic retinopathy (PDR) induced rubeosis and, b) in treatment of…
- Trial name
- NCT01069341
- Testing
- Ranibizumab
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Bhagat, Neelakshi, M.D., M.P.H.
Cystoid Macular Edema
Macugen to Prevent Worsening of Macular Edema Following Cataract Surgery in Diabetics
This research is being conducted to look at the effects of an intraocular drug (pegaptanib, also called Macugen) for the treatment of swelling in the retina (the light sensitive tissue in the back of the eye) that often occurs…
- Trial name
- NCT00346983
- Testing
- Pegaptanib sodium, Control
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University
Diabetic Retinopathy
Comparison of Diabetes Retinopathy Among Type 2 Diabetic Patients Treated With Different Regimens
Diabetic retinopathy (DR) is an important cause of blindness.
- Trial name
- CORRECT (NCT02587741)
- Testing
- Metformin, Lantus, Novomix30
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Diabetes, Retinal Disorders
Rapid, Non-invasive, Regional Functional Imaging of the Retina. (Diabetic Retinopathy Diagnosis Device)
The basic objective of this project is to test a modification of existing technology for monitoring the responses of the pupil to light as a method for detecting regional losses of function of the retina.
- Trial name
- NCT01546766
- Testing
- Pupillometry testing.
- Where
- 2 sites in United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Diabetic Retinopathy
Changes of Macular Vasculature After Uncomplicated Phacoemulsification Surgery Using Optical Coherence Tomography Angiography
To record the vascular changes that may be present in the macular after uncomplicated phacoemulsification surgery by using OCTA, a comparative study between healthy and diabetic patients
- Trial name
- NCT04594603
- Testing
- Phacoemulsification for cataract
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Diabetic Macular Edema, Diabetic Retinopathy
Unilateral Bevacizumab for Bilateral Diabetic Macular Edema
The endothelial growth factor (VEGF), has been implied in the genesis of diverse Neovascular disease. In the industrialized and developing countries, the main cause of blindness is the diabetic retinopathy.
- Trial name
- NCT00496405
- Testing
- bevacizumab
- Where
- Mexico
- Sponsor
- Asociación para Evitar la Ceguera en México
Blindness, Diabetic Retinopathy
Early Treatment Diabetic Retinopathy Study (ETDRS)
To evaluate the effectiveness of both argon laser photocoagulation and aspirin therapy in delaying or preventing progression of early diabetic retinopathy to more severe stages of visual loss and blindness.
- Trial name
- NCT00000151
- Testing
- Aspirin, Argon Laser Photocoagulation
- Sponsor
- National Eye Institute (NEI)
Neovascular
Panretinal Photocoagulation for Proliferative Diabetic Retinopathy in a Single Session Using Low Fluence Parameters
Is it possible to do a panretinal photocoagulation for proliferative diabetic retinopathy in a single session using low fluence parameters?
- Trial name
- PFC (NCT01023698)
- Testing
- laser photocoagulation
- Volunteers
- 30 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Diabetic Retinopathy
Evaluation of Retinal Changes in Systemic Darbepoetin Alpha Treatment in Patients With Diabetes Mellitus
The purpose of this study is to determine whether systemic administration of darbepoetin alpha results in the progression or regression of diabetic macular edema.
- Trial name
- EPOinDR (NCT00704652)
- Where
- Austria
- Volunteers
- 5 people
- Sponsor
- Medical University of Vienna
Diabetic Retinopathy
Clinical Decision Support Algorithm to Predict Diabetic Retinopathy
Diabetic retinopathy (DR), a complication of diabetes, is a leading cause of blindness among working-aged adults globally. In its early stages, DR is symptomless, and can only be detected by an annual eye exam.
- Trial name
- NCT03769948
- Testing
- risk factors for diabetic retinopathy
- Volunteers
- 500 people
- Sponsor
- Oklahoma State University Center for Health Sciences
Proliferative Diabetic Retinopathy
Propranolol for Diabetic Retinopathy
This study is investigating if the oral beta antagonist propranolol can induce regression of retinal neovascularization associated with proliferative diabetic retinopathy.
- Trial name
- NCT01535495
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Wisconsin, Madison
Type 1 Diabetes, Diabetic Retinopathy
Microvascular Changes in OCT-angiography in Type 1 Diabetes Mellitus at the Onset of the Disease and After Optimization of Glycemic Control.
The objective of the study is to evaluate the differences in the retinal microcirculation measured by OCT-Angiography in patients with type 1 diabetes between the diagnosis of the disease and after 3 months of insulin treatment.
- Trial name
- NCT04888598
- Testing
- Optical Coherence Tomography (OCT) Angiography
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Diabetic Retinopathy, Neurodegeneration
Retinal Neurodegenerative and Vascular Changes in Diabetic Patients
Using Optical Coherence Tomography and ImageJ software the investigators will analyze retinal and choroidal vascular changes and their impact on retinal layers among patients with diabetes without retinopathy and patients with…
- Trial name
- NCT04637217
- Testing
- Optical Coherence Tomography
- Where
- Romania
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Diabetes Mellitus, Diabetic Retinopathy
Efficacy and Safety of AEYE-DS Software Device for Automated Detection of Diabetic Retinopathy From Digital Fundus Images
AEYE-DS is a software device developed to increase compliance with diabetic retinopathy screening by automatically detecting more-than-mild diabetic retinopathy from digital fundus images using Artificial Intelligence (AI)-based…
- Trial name
- NCT04612868
- Testing
- AEYE Software Device
- Where
- United States
- Volunteers
- 531 people
- Sponsor
- AEYE Health Inc
Diabetic Retinopathy
Triamcinolone Acetonide Injections to Treat Diabetic Macular Edema
This study will evaluate which of the three following treatment options is better for diabetic macular edema: laser alone, steroid injection alone, or steroid injection followed by laser.
- Trial name
- NCT00231023
- Testing
- Peribulbar Triamcinolone Acetonide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Eye Institute (NEI)
Diabetic Retinopathy, Retinal Degeneration
The Effect of Laser Treatment on Macular Pigment of Eye in Cases With Diabetes
It has been hypothesized that thermal damage of laser pan-retinal photocoagulation may affect macular pigment as well as inner layer cells in the retina, so it was aimed to investigate possible effect of conventional laser…
- Conditions
- Diabetic Retinopathy, Retinal Degeneration, Macula Abnormality, Laser Burn of Retina
- Trial name
- NCT03150654
- Testing
- Laser pan-retinal photocoagulation
- Volunteers
- 36 people
- Sponsor
- Afyon Kocatepe University Hospital
Proliferative Diabetic Retinopathy
Gene Expression in Patients With Epiretinal Membranes
The purpose of this study was to investigate the expression of selected genes both in epiretinal membranes (ERMs) and peripheral blood mononuclear cells (PBMCs) from patients with primary and secondary epiretinal membranes in…
- Trial name
- NCT01946451
- Where
- Poland
- Sponsor
- Medical University of Silesia
Age Related Macular Degeneration, Intravitreal Injections
Aflibercept in Recurrent or Persistent CNV
Age-related macular degeneration (AMD) and diabetic retinopathy are among the most common disorders causing visual disability in elderly people. AMD leads to dysfunction and loss of photoreceptors in the central retina.
- Conditions
- Age Related Macular Degeneration, Intravitreal Injections, Diabetic Macular Edema
- Trial name
- OPHTH-010915 (NCT02669953)
- Testing
- Aflibercept
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Medical University of Vienna
Diabetic Macular Edema
A Safety and Efficacy Study of Oral Danazol (a Previously Approved Drug) in the Treatment of Diabetic Macular Edema.
This study will evaluate the efficacy of ultra low dose danazol (Optina™) for the treatment of diabetic macular edema.
- Trial name
- NCT01821677
- Testing
- Danazol Capsules
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Ampio Pharmaceuticals. Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.