Clinical trials: Diagnoses Disease
Myeloma Multiple
Minimal Residual Disease Guided Maintenance Therapy With Belantamab Mafodotin and Lenalidomide After Autologous Hematopoietic Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma
To increase the conversion rate from MRD-positive to MRD-negative CR in patients with newly diagnosed multiple myeloma (NDMM) receiving post-transplant maintenance therapy with belantamab mafodotin plus lenalidomide.
- Trial name
- NCT05091372
- Testing
- Belantamab mafodotin, Lenalidomide
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Arthritis of Knee, Normal Knee
Analysis of Joint Sounds in the Diagnosis of Knee Disorders
Clinical-noninvasive recording of sounds from the knees through a brief loaded range of motion. Description in phase 1 analytic but descriptive as well in phase 2. No samples other than a sound recording.
- Conditions
- Arthritis of Knee, Normal Knee, Knee Arthroscopy
- Trial name
- Joint (NCT02294045)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Malaria
P. Falciparum Infection Dynamics and Transmission to Inform Elimination
In the current study, three experimental approaches aiming at reducing malaria transmission will be tested. The study will cover two transmission season (2019 and 2020) and the interventions will vary by season.
- Trial name
- INDIE-1b (NCT04053907)
- Testing
- Community Case Management, Weekly fever screening and treatment, Monthly malaria screening
- Where
- The Gambia
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Congenital Adrenal Hyperplasia
Cardiovascular Risk Profile in Patients With Congenital Adrenal Hyperplasia
Treatment with glucocorticoids and mineralocorticoids has changed congenital adrenal hyperplasia (CAH) from a fatal to a chronic lifelong disease.
- Trial name
- cardiohcs (NCT01807364)
- Where
- France
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Irritable Bowel Syndrome (IBS)
Deep Learning-Based Confocal Laser Microendoscopy Feature Atlas Construction and Its Application in Intelligent Diagnosis of Irritable Bowel Syndrome
In this study, the healthy control group and IBS patients are taken as the research subjects, and CLE is applied to image and analyze the enrolled persons respectively, to derive and compare the characteristic microstructural…
- Trial name
- NCT07051226
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Congenital Adrenal Hyperplasia
Qualitative Research on Women With Congenital Adrenal Hyperplasia
This qualitative interview-based study will investigate the impact that living with congenital adrenal hyperplasia has for women in the following areas: health-related quality of life (HRQL), psychological health, and…
- Trial name
- CAH (NCT00559078)
- Testing
- Interview
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lehigh University
Artificial Intelligence (AI), Artificial Intelligence (AI) in Diagnosis
A Multi-center Study on Artificial Intelligence-Based Quantitative Evaluation of Echocardiography
This project aims to collaborate with multiple medical institutions to verify the accuracy, stability, and clinical application value of AI algorithms in echocardiographic quantitative measurement through multi-center clinical…
- Conditions
- Artificial Intelligence (AI), Artificial Intelligence (AI) in Diagnosis, Cardiovascular Diseases (CVD), Echocardiography
- Trial name
- MAIQUEE (NCT07133516)
- Where
- 37 sites in China
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Lung Cancer
Oral Microbiome Diagnostics of Lung Cancer
The study aims to develop a deep learning-based diagnostic method for lung cancer using the oral microbiome. This innovative approach involves establishing an observational cohort of 576 individuals, including lung cancer…
- Trial name
- NCT06270992
- Testing
- NCCN (National Comprehensive Cancer Network) diagnosis
- Where
- Turkey (Türkiye)
- Volunteers
- 676 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Lung Cancer
An App to Identify Radiation Pneumonitis - a Pre-Study in Healthy Volunteers
Radiation pneumonitis is a possible side effect of radiotherapy for lung cancer. Since it often occurs only several weeks following radiotherapy, the corresponding symptoms may not be associated with previous administered…
- Trial name
- POLCAR-HV (NCT07824544)
- Testing
- PneumoCheck app
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Pneumonia Childhood
Acute Respiratory Infection Diagnostic Aids (ARIDA) Controlled Accuracy Evaluation Protocol
Pneumonia is the leading infectious cause of death among children under 5 years of age globally. Many pneumonia deaths result from late care seeking and inappropriate treatment due to misdiagnosis of symptoms.
- Trial name
- NCT03067558
- Testing
- Children's automated respiratory rate monitor, MK2 Acute Respiratory Infection (ARI) Timer
- Where
- Ethiopia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Malaria Consortium
Bruxism, Sleep-Related
Smartwatch Analysis of Sleep Bruxism
This study aims to investigate the differences in sleep stages and total sleep duration between individuals diagnosed with sleep bruxism and healthy controls.
- Trial name
- NCT07453121
- Testing
- Smartwatch-based Sleep Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Cappadocia University
Prostate Cancer With PSA Gray Zone
Intelligent Screening and Precision Diagnosis of Prostate Cancer Based on Multimodal Data
This project aims to develop a precision screening and diagnostic solution for prostate cancer based on multimodal artificial intelligence, focusing on addressing the diagnostic challenge in patients within the PSA "gray zone" of…
- Trial name
- NCT07631806
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Cardiomyopathy, Hypertrophic
Prognosis of Subjects With Unexplainable Precordial Deep T-wave Inversion Without Wall Thickness> 15mm
The investigators sought to evaluate the morphological and functional changes and prognosis of participants with unexplainable precordial deep T-wave inversion on ECG and with apical thickness less than 15mm.
- Trial name
- NCT02692508
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Hepatitis C, Diagnostic Self Evaluation
HCV Self-testing in Pakistan
To achieve the goal of elimination of hepatitis C infection in Pakistan, the strategy of elimination needs to be increasingly directed towards case finding through mass screening in rural or peri-urban communities to identify and…
- Trial name
- NCT04971538
- Testing
- OraQuick® HCV Self-Test
- Where
- Pakistan
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Healthy
A Trial to Learn if a COVID-19 Therapeutic is Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants
The primary objective of the study is to evaluate the safety and tolerability of REGN14284 in healthy participants, as measured by all treatment-emergent adverse events (TEAEs) and treatment-emergent serious adverse events…
- Trial name
- NCT05505448
- Testing
- REGN14284
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Cardiac Toxicity, Chemotherapeutic Agent Toxicity
Cardiac Magnetic Resonance Imaging in Patients With Non-Hodgkin Lymphoma or Hodgkin Lymphoma Receiving Doxorubicin
RATIONALE: Diagnostic procedures, such as cardiac magnetic resonance imaging, may help doctors detect early changes in the heart caused by chemotherapy.
- Conditions
- Cardiac Toxicity, Chemotherapeutic Agent Toxicity, Lymphoma
- Trial name
- NCT00577798
- Testing
- contrast-enhanced magnetic resonance imaging
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Scansys, Pentacam
A Study of a Novel Scheimpflug Device in Diagnosing Keratoconus
Comparison of the screening and diagnosis ability of the novel Scheimpflug-based tomography device (Scansys) with Pentacam and the Scheimpflug-based biomechanics device (Corvis ST) for keratoconus.
- Conditions
- Scansys, Pentacam, Corvis ST, Keratoconus
- Trial name
- NCT06119321
- Testing
- Pentacam, Corvis ST and Scansys
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Non-communicable Diseases (NCD), Neoplams
Health for Hungary (H4H) - Longitudinal Collection of Blood Samples and Corresponding Data
The Health for Hungary (H4H) study collects blood samples and corresponding health data to investigate healthy aging and health-to-disease transitions in middle-aged and elderly participants.
- Conditions
- Non-communicable Diseases (NCD), Neoplams, Cancer, Lung Cancer (NSCLC)
- Trial name
- H4H (NCT07743021)
- Where
- 33 sites in Hungary
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Center for Molecular Fingerprinting Research Nonprofit LLC
Cancer
Diagnosis of Cancer Using Breath Samples
The purpose of this study is to collect breath samples from healthy and cancer sick patients. The breath, collected to special bags, will be transferred to laboratories in the Technion and analyzed using an electronic nose system…
- Trial name
- NCT01234987
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Technion, Israel Institute of Technology
Positron-Emission Tomography, Magnetic Resonance Imaging
Early Diagnosis of Therapy-associated Cardiotoxicity Basing on Multi-tracer Multimodality PET/MRI
Using Multi-tracer to early diagnosis of therapy-associated cardiotoxicity using multimodality PET/MRI.
- Trial name
- NCT04555642
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
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