Clinical trials: Diagnosis of Bone Quality
Osteoporosis, Growth Hormone Deficiency
Randomized Study of Growth Hormone on Bone Mineral Density in Patients With Adult Onset Growth Hormone Deficiency
OBJECTIVES: I. Compare whether the bone tissue in the spine and hip improves in patients with adult onset growth hormone deficiency treated with growth hormone (GH) vs placebo. II.
- Trial name
- NCT00006394
- Testing
- growth hormone
- Where
- 7 sites in United States
- Volunteers
- 72 people
- Sponsor
- National Center for Research Resources (NCRR)
Growth Hormone Deficiency
Observational Longitudinal Study in Children Affected by Idiopathic Growth Hormone Deficiency (GHD)
The aim of this study is to assess the developmental patterns of lung function in children affected by growth hormone deficiency after one year of GH therapy.The assessment by specific questionnaires of quality of life and of…
- Trial name
- GHD (NCT02507245)
- Testing
- Growth Hormone-Releasing Hormone
- Volunteers
- 48 people
- Sponsor
- Stefania La Grutta, MD
Marfan Syndrome, Marfan Syndrome Cardiovascular Manifestations
Living With Marfans and Your Aorta: Surgical Outcomes Study
Marfan Syndrome (MFS) is a genetic disease affecting the eyes, skeleton, heart and arteries. Despite MFS affecting multiple organ systems, cardiovascular manifestations are the most serious and life threatening.
- Trial name
- LIMA II (NCT04776681)
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Barts & The London NHS Trust
Lumbar Disc Herniation
Effects of Whole-Body Electromyostimulation Application in Individuals With Lumbar Disc Hernia
To determine the effects of WB-EMS application on balance, pain, muscle strength, muscle endurance, flexibility, muscle shortening and quality of life in individuals with Lumbar Disc Hernia and compare it with individuals who…
- Trial name
- NCT04329598
- Testing
- Whole-Body Electromyostimulation Group, Exercise Group
- Where
- 2 sites in Cyprus
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Osteogenesis Imperfecta
Registry of Osteogenesis Imperfecta
ROI is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains…
- Trial name
- ROI (NCT04115774)
- Testing
- bisphosphonates
- Where
- Italy
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Minimally Invasive Surgical Procedures, Disk, Herniated
Therapeutic Exercises and Educational Sessions After Microdiscectomy for Disc Herniation
The basic purpose of current research is to evaluate the comparative effectiveness of therapeutic exercises and educational sessions after microdiscectomy through Minimally Invasive Surgery for disc herniation.
- Trial name
- NCT04144452
- Testing
- Patient Education Session, Therapeutic Exercise plus educational session
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Ghurki Trust and Teaching Hospital
Spine Osteoarthritis, Spa Resorts
Effectiveness of Spa Treatment, Outpatient Physiotherapy and no Physiotherapy in Spine Osteoarthritis
In the first study group will participate patients with spine osteoarthritis who will be treated in polish spas in Subcarpathian Region. Complex physiotherapy including balneotherapy will be applied in study group participants.
- Trial name
- NCT03974308
- Testing
- Comprehensive physiotherapy including balneotherapy and filling questionaire, Comprehensive physiotherapy without balneotherapy and filling questionaire, No intervention, only filling questionaire
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- University of Rzeszow
Cognitive Decline, Sleep
Fish Oil for Cognitive Function, Sleep Quality, and Bone Density
The Precision Nutritional Management for Diabetes trial (PNMD; NCT03708887) is a randomized clinical trial in 415 diabetic patients investigating whether taking daily dietary supplements of omega-3 fatty acids (1.5 or 3 grams)…
- Conditions
- Cognitive Decline, Sleep, Bone Mineral Density
- Trial name
- NCT06614374
- Testing
- Low-dose fish oil capsules, High-dose fish oil capsules, Refined olive oil
- Where
- China
- Volunteers
- 415 people
- Sponsor
- Jingjing Jiao
Scoliosis Idiopathic Adolescent, Dysmenorrhea
Effect of Myofascial Release on Scoliotic Females With Dysmenorrhea.
PURPOSE: The purpose of this study is to determine the effect of myofascial release on spinal curvature, premenstrual symptoms, and quality of life in scoliotic females with dysmenorrhea
- Conditions
- Scoliosis Idiopathic Adolescent, Dysmenorrhea, Premenstrual Syndrome, Quality of Life
- Trial name
- NCT05817513
- Testing
- Myofascial release., Traditional exercises for scoliosis treatment.
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cancer Survivors
Virtual Exercise Training and Its Impact on Bone Compartments in Adult Survivors of Childhood Cancer
Childhood cancer is a rare disease but a significant cause of death in children and adolescents. The incidence of childhood cancer is 1case per 300 cases of adult cancer, but surviving to it has important sequels.
- Trial name
- 3D-BONE (NCT07022262)
- Testing
- Progressive resistance training plus impact loading
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Universidad de Granada
Minor, Scoliosis; Juvenile
Evaluation of a Prehabilitation Program in Patients Requiring Scoliosis Surgery.
Scoliosis is a curvature of the spine that, in the most severe cases, may require surgical treatment. This surgery is invasive and complex, causing anxiety for children, adolescents, and their parents.
- Conditions
- Minor, Scoliosis; Juvenile, Scoliosis; Adolescence, Surgery
- Trial name
- PHYPSYSCOL (NCT07852286)
- Testing
- Pre-habilitation program
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Spinal Stenosis, Spondylolisthesis
Decompression vs. Fusion for Stable Degenerative Spondylolisthesis
The purpose of this study is to assess the feasibility of a full-scale multicenter randomized, controlled trial comparing the effectiveness of two surgical treatments for a condition associated with lumbar spinal stenosis called…
- Trial name
- NCT02348645
- Testing
- Spinal fusion, Spinal decompression
- Where
- 8 sites in Canada
- Volunteers
- 70 people
- Sponsor
- University Health Network, Toronto
Cerebral Palsy, Scoliosis
Effects of Neuromuscular Scoliosis Surgery on Nutritional Metabolism
Cerebral palsy is the primary cause of disability in France. It is a non-progressive condition leading to movement and posture troubles, but also to cognitive and sensory problems.
- Trial name
- SORONOUS (NCT07255495)
- Testing
- Absorptiometry and indirect calorimetry, Questionnaires
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Montpellier
Myeloid Leukemia, Chronic, Chronic-Phase
Treating Patients With Chronic Myeloid Leukemia (CML) in Chronic Phase (CP) With Dasatinib
CML requires ongoing treatment and assessment of treatment milestones in order to manage the disease properly. Dasatinib is approved for the treatment of newly diagnosed PH+ CP-CML and CML in chronic or accelerated phase or blast…
- Trial name
- DasPAQT (NCT02348957)
- Where
- 66 sites in Germany
- Volunteers
- 223 people
- Sponsor
- Onco Medical Consult GmbH
Lumbar Spinal Stenosis
Effects of a Walking Program on Functional Status of Post-Surgical Lumbar Spinal Stenosis Patients
Overall Objective: To evaluate the efficacy of an interventional walking program on the quality of life and functional status of patients with Lumbar Spinal Stenosis, post-surgery, using subjective (VAS, ODI, RMDQ, SF-36), and…
- Trial name
- NCT00958490
- Testing
- Walking program
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Bone Sarcoma, Soft Tissue Sarcoma (STS)
"Exercise Intervention to Increase Physical Activity in Young Sarcoma Survivors (Sport Ist Herzenssache)"
Survivors of bone and soft tissue sarcoma often face long-term health problems after their cancer treatment, such as muscle weakness, joint stiffness, and reduced heart and lung fitness.
- Trial name
- NCT07729059
- Testing
- Individualized Exercise Program
- Volunteers
- 46 people
- Sponsor
- Universität Duisburg-Essen
Osteoporosis
Effects of Exoskeleton-Assisted Gait Training on Bone Health and Quality of Life
This is a randomized clinical trial to quantify the effects of exoskeleton-assisted gait on the musculoskeletal system and health-related quality of life.
- Trial name
- NCT02533713
- Testing
- Exoskeleton assisted gait training
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Craig Hospital
Myelodysplastic Syndromes, Transfusion-dependent Anemia
Impact of 2 Transfusion Strategies on Quality of Life of Multitransfused Patients With Low-risk Myelodysplastic Syndrome
Myelodysplastic syndromes (MDS) are heterogeneous malignant bone marrow disorders characterized by ineffective haematopoiesis, peripheral blood cytopenias and variable risk of leukaemia transformation.
- Trial name
- SMD-transfu (NCT03643042)
- Testing
- Transfusion
- Where
- 19 sites in France
- Volunteers
- 11 people
- Sponsor
- Lille Catholic University
Ankylosing Spondylitis, Arthritis, Psoriatic
Study Evaluating the Safety of Etanercept in Rheumatoid Arthritis, Ankylosing Spondylitis and Psoriatic Arthritis
This is a Phase 4 open label, non-interventional, multi-center study to evaluate the safety of Enbrel (etanercept) treatment in patients receiving etanercept 25mg sc twice weekly or 50mg of etanercept once weekly.
- Conditions
- Ankylosing Spondylitis, Arthritis, Psoriatic, Arthritis, Rheumatoid, Spondylitis, Ankylosing
- Trial name
- NCT00273858
- Testing
- There is no Intervention. The study is observational.
- Where
- 9 sites in Greece
- Volunteers
- 880 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Osteopenia, Bone Turnover Markers
Effects of Physical Training on Bone Turnover and Quality of Life in Osteopenic Postmenopausal Women.
The aim of our research was to define both in vivo and in vitro whether and to what extent an high-impact exercise program would affect bone cell turnover and improve the QoL in osteopenic postmenopausal women.
- Conditions
- Osteopenia, Bone Turnover Markers, Quality of Life
- Trial name
- NCT03195517
- Testing
- Physical exercise
- Volunteers
- 33 people
- Sponsor
- University Of Perugia