Clinical trials: Diagnosis of Bone Quality
Hypochondroplasia
Open-Label, Long-Term, Extension Study of Infigratinib in Children With Hypochondroplasia
Phase 2, multicenter, OLE study to evaluate the long-term safety, tolerability, and efficacy of infigratinib, an FGFR (fibroblast growth factor receptor) 1-3-selective tyrosine kinase inhibitor, in participants with…
- Trial name
- NCT07393373
- Testing
- Infigratinib
- Where
- 24 sites in United States, Australia and 8 more
- Volunteers
- 135 people
- Sponsor
- QED Therapeutics, a BridgeBio company
Scoliosis, Radiation Exposure
Inter-variability in Radiographic Fluoroscopic Technique in Patients With Idiopathic Scoliosis
Radiographical images in Adolescent idiopathic scoliosis (AIS) can have a potential radiation-induced oncogenic effect. In this study, the investigators aim to compare a fluoroscopic imaging technique (LFT) with traditional…
- Conditions
- Scoliosis, Radiation Exposure, Evaluable
- Trial name
- IVIS (NCT05673473)
- Testing
- scoliosis radiographs
- Volunteers
- 342 people
- Sponsor
- christian wong
Spinal Stenosis, Intermittent Claudication
Outcome of Surgery for Lumbar Spinal Stenosis - a Comparison of Data From Three National Quality Registries
There is no international consensus on evaluation and surgical treatment of Lumbar Spinal Stenosis (LSS). The indication for operative treatment is relative, and the variation in surgical rates and procedures is significant, both…
- Trial name
- NCT02897947
- Testing
- Surgery for lumbar spinal stenosis in Norway, Surgery for lumbar spinal stenosis in Sweden, Surgery for lumbar spinal stenosis in Denmark
- Volunteers
- 7,500 people
- Sponsor
- St. Olavs Hospital
Osteoporosis
Effect of Progressive Loading Protocol on Bone Mineral Density
The aims of this study are to examine the effects of Progressive Loading Exercises Protocol on Bone Mineral Density in osteoporotic patient's well-being and quality of life before a fracture occurs in order to create remedies.
- Trial name
- NCT05889104
- Testing
- Randomization Program, Progressive Loading Protocol (PLP):
- Where
- Saudi Arabia
- Volunteers
- 92 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Idiopathic Scoliosis
Scoliosis Surgery Using the PASS® LP System
The purpose of this study is to find out the outcomes of using the PASS LP System to correct idiopathic scoliosis. This system is a unique set of spinal instrumentation used to surgically correct the rotation and deformity of the…
- Trial name
- NCT01019109
- Testing
- Posterior Spinal Fusion Device: Titanium rod arm used titanium rods, and CoCr rod arm used Cobalt Chrome rods as a part of the construct.
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Medicrea, USA Corp.
Osteoporosis
Kinesiophobia in Postmenopausal Osteoporosis
This study aims to evaluate kinesiophobia levels in postmenopausal women with osteoporosis compared to a healthy control group and to explore the relationships between kinesiophobia and various psychosocial factors, including…
- Trial name
- NCT06520709
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Beylikduzu State Hospital
Hematological Malignancies
RCT to Investigate Whether an Exercise Programme Improves the Physical Performance and QOL After BMT
The hypothesis is that exercise will improve the physical performance and quality of life of bone marrow/ haemopoietic stem cell transplants.The aim of the trial is to provide definite clinical evidence as to which( if any) type…
- Trial name
- NCT00163644
- Testing
- aereobic plus resisted exercise, aerobic plus active exercise, No formal exercise plus phone calls
- Where
- Australia
- Volunteers
- 66 people
- Sponsor
- Bayside Health
Lumbar Disc Herniation
VR Therapy Effects in Lumbar Disc Herniation
This study aims to evaluate the effects of incorporating virtual reality (VR) therapy into routine physical therapy (RPT) on balance, pain, kinesiophobia, quality of life, and depression in individuals diagnosed with lumbar disc…
- Trial name
- NCT07309627
- Testing
- Conventional Physiotherapy, VR
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Uskudar University
Breast Cancer
Assessment of Quality of Life, Bone Density and Safety in Postmenopausal Breast Cancer Patients With Letrozole Therapy
To compare the overall QoL (Quality of Life) using Trial Outcome index (TOI) of FACT-B questionnaire for 3 years from baseline.
- Trial name
- NCT00913016
- Where
- South Korea
- Volunteers
- 897 people
- Sponsor
- Korean Breast Cancer Study Group
Prostate Cancer
A Study to Learn More About How Radium-223 Affects the Quality of Life of Colombian Patients With Prostate Cancer That Has Not Responded to Testosterone Lowering Treatment and Has Spread to the Bones, and to Better Understand Its Safety
The study drug, radium-223, gives off radiation that helps to kill cancer cells in the prostate. It is already available for patients to receive as a treatment for prostate cancer that has not responded to testosterone lowering…
- Trial name
- QOLRAD (NCT04681144)
- Testing
- Radium-223-dichloride (Xofigo, BAY88-8223)
- Where
- Colombia
- Volunteers
- 103 people
- Sponsor
- Bayer
Cancer, Bone Marrow Neoplasms
The PRISM Intervention for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation
Multisite Randomized Controlled Trial (RCT) testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults receiving hematopoietic cell transplantation for hematology…
- Conditions
- Cancer, Bone Marrow Neoplasms, Anxiety, Depression
- Trial name
- NCT03640325
- Testing
- PRISM (Promoting Resilience in Stress Management)
- Where
- 5 sites in United States
- Volunteers
- 143 people
- Sponsor
- Seattle Children's Hospital
Conductive Hearing Loss
Audiological Benefit and Quality of Life With Two Bone Conduction Systems: ADHEAR vs. Contact Mini
Patients with conductive hearing loss fitting the inclusion criteria will be asked to participate in the study. All subjects will be randomized to wear either first the adhesive or the conventional bone conduction hearing aid.
- Trial name
- NCT03746548
- Testing
- Adhear, Contact Mini (CM)
- Where
- Austria
- Volunteers
- 13 people
- Sponsor
- Dominik Riss
Dynapenia, Abdominal Obesity
Effectiveness of Whole Body Vibration on Health Outcomes in Older Adults With Dynapenic Abdominal Obesity
This study focuses on whole body vibration training (WBVT), a form of neuromuscular training that uses mechanical vibrations. WBVT has been shown to improve muscle function, bone mineral density, and quality of life.
- Trial name
- NCT07180485
- Testing
- whole body vibration training, control group
- Volunteers
- 120 people
- Sponsor
- Dalin Tzu Chi General Hospital
Lumbar Disc Herniation
Flexion-Distraction Technique
This prospective, two-center, non-randomized controlled study compared the effects of conventional physical therapy (CPT) and Cox flexion-distraction therapy (CFT) on pain, lumbar range of motion, disability, and health-related…
- Trial name
- FDT (NCT06886334)
- Testing
- exercise, Cox flexion-distraction therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Istanbul Medipol University Hospital
Prostatic Neoplasms
Bicalutamide Monotherapy Has Significant Quality of Life Benefits for Men With Advanced Prostate Cancer
The aim of this study is to comprehensively monitor the effects of a nonsteroidal antiandrogen in patients requiring hormone manipulation for prostate cancer
- Trial name
- NCT00551044
- Testing
- Bicalutamide
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Myelodysplastic Syndromes
Observational Study Towards the Impact of Newly Started Treatment in MDS on QoL
Study type An observational study conducted in different hematological centers in Belgium. Study objectives Primary objective: To assess the impact of newly started treatments on the QOL of patients suffering from myelodysplastic…
- Trial name
- Be-QUALMS (NCT04053933)
- Where
- 21 sites in Belgium
- Volunteers
- 70 people
- Sponsor
- University Hospital, Antwerp
Kyphosis
Yoga for Kyphosis Trial
This study seeks to determine whether a specially designed Hatha Yoga program can reduce hyperkyphosis in men and women who are at least 60 years of age and who have excessive thoracic kyphosis.
- Trial name
- NCT00781729
- Testing
- Yoga, one hour class, 3 times per week, for 24 weeks, Luncheon Seminar Series, once per month, for 24 weeks
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Quality of Life, Acromegaly
Change in Quality of Life After Addition of Weekly 40 mg Pegvisomant/Placebo in Controlled Acromegalic Patients
Study Synopsis Study Title: Double blind, single centre, cross-over study on the effects of weekly subcutaneous administration of 40 mg pegvisomant or placebo on quality of life and insulin sensitivity in acromegalic patients…
- Trial name
- mec-2005-290 (NCT00642720)
- Testing
- Pegvisomant
- Volunteers
- 20 people
- Sponsor
- Erasmus Medical Center
Breast Carcinoma Metastatic to the Bone
Study of the Utility of the BOMET-QOL Questionnaire Patients With Breast Cancer and Bone Metastasis
Epidemiological, prospective and multicenter study to evaluate the utility of the BOMET-QoL questionnaire in patients with breast cancer (BC) and bone metastases (BM).
- Trial name
- MAbomet (NCT03847220)
- Testing
- BOMET-QoL questionnaire
- Where
- 15 sites in Spain
- Volunteers
- 241 people
- Sponsor
- Spanish Breast Cancer Research Group
Inflammatory Arthritis
Effect of a Self-Management Intervention for Patients Newly Diagnosed With Inflammatory Arthritis: The NISMA Trial
Background: In patients newly diagnosed with inflammatory arthritis, a self-management intervention is anticipated to enhance self-management skills, thereby improving patient function, well-being, and survival.
- Trial name
- NCT06533423
- Testing
- Newly diagnosed with Inflammatory arthritis - a Self-MAnagement intervention (NISMA)
- Where
- 2 sites in Denmark
- Volunteers
- 130 people
- Sponsor
- Glostrup University Hospital, Copenhagen