Clinical trials: Diagnostic Imaging Utilization
Prostate Adenocarcinoma, Stage IIC Prostate Cancer AJCC v8
Androgen Deprivation Therapy (Relugolix) for the Improvement of Diagnostic Imaging (PSMA PET/CT Scan) in Patients With High Risk or Very High Risk Prostate Cancer, The EnrichPSMA Trial
This phase II trial studies how well a short course of androgen deprivation therapy (ADT) with relugolix works in increasing expression of prostate-specific membrane antigen (PSMA) and improving diagnostic imaging with PSMA…
- Conditions
- Prostate Adenocarcinoma, Stage IIC Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8
- Trial name
- NCT07025369
- Testing
- Biospecimen Collection, Computed Tomography, Flotufolastat F-18 Gallium
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Rheumatoid Arthritis, Polyarthritis
The Use of Anti-CD4 Monoclonal Antibody (mAb)-Fragment for the Imaging of Chronic Inflammation in Patients With Active Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a disease with a large economic impact due to the long lasting disabling nature of the disease. Furthermore, diagnosis of the disease is difficult and only a scheme with different symptoms is used to…
- Conditions
- Rheumatoid Arthritis, Polyarthritis, Rheumatism, Autoimmune Disease
- Trial name
- NCT00372177
- Testing
- Fab-fragment of Anti-human CD4
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- Biotectid GmbH
Nicotine Dependence
A Brain Imaging Study of Nicotine Release in Cigarette Smokers
Tobacco Smoking is the most prevalent addiction in society today causing directly major health hazards and sharing morbidity with other psychiatric disorders.
- Trial name
- NCT00254358
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Healthy, Magnetic Resonance Imaging
Development of Techniques for Use in MRI With a Magnetic Field of 7 Tesla
This study will develop new techniques for optimizing resolution in magnetic resonance imaging (MRI) with a high magnetic field of 7 Tesla.
- Trial name
- NCT00056914
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Magnetic Resonance Imaging
The Use of a Mock MRI Scanner for Reducing the Use of Anesthesia in Children Undergoing Clinical MRI Scans
Diagnostic Magnetic Resonance (MR) imaging procedures can be stressful for children and parents. Patients must lie still during the procedure to provide diagnostic quality images.
- Trial name
- NCT02630342
- Testing
- Mock MRI scanner, Preparation materials, Child Life Specialist preparation
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Calgary
Breast Cancer
Use of Compressed Sensing in Breast MRI
Breast MRI is increasingly important in breast screening imaging. It is currently based on dynamic sequences after contrast injection whose temporal resolution must be less than 90 seconds with dynamic acquisitions at different…
- Trial name
- COMPRIM (NCT02826369)
- Testing
- 3.0 Tesla in Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Institut de Cancérologie de Lorraine
Healthy
Use of Real-Time Functional Magnetic Resonance Imaging Neurofeedback to Improve Motor Function in Cerebellar Ataxia
This project will study the feasibility of motor rehabilitation in people with cerebellar ataxia using real-time functional magnetic resonance imaging neurofeedback (rt-fMRI NF) in conjunction with motor imagery.
- Trial name
- fMRI (NCT05436249)
- Testing
- Neurofeedback treatment, At-home therapy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Wound
Evaluation of MolecuLight i:X as an Adjunctive Fluorescence Imaging Tool to Clinical Signs and Symptoms for the Identification of Bacteria-containing Wounds
This is a non-randomized evaluation for which 160 adult patients will be imaged at outpatient wound care clinics who present with a wound of unknown infection diagnostic status and are receiving standard treatment.
- Trial name
- NCT03540004
- Testing
- MolecuLight i:X Imaging Device
- Where
- 14 sites in United States
- Volunteers
- 367 people
- Sponsor
- MolecuLight Inc.
Alcohol Use Disorder (AUD), Alcoholism
Repetitive Transcranial Magnetic Stimulation for Alcohol Use Disorder
This study looked at whether repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation treatment, could help adults with alcohol use disorder when added to their usual treatment.
- Trial name
- NCT07755046
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Taiwan
- Volunteers
- 9 people
- Sponsor
- Ting-Gang Chang
Hyperparathyroidism, Primary
Autofluorescence in Surgery for Primary Hyperparathyroidism
The study aims to test if autofluorescence imaging (AF) is a useful surgical aid during parathyroidectomy (PTX) for primary hyperthyroidism (PHPT).
- Trial name
- NCT06230380
- Testing
- Surgery with autofluorescence
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital
Brain Cancer, Arthritis, Rheumatoid
Assessing the Suitability of an Imaging Probe for Use in Clinical Cell and Gene Therapy Trials in Cancer and Rheumatoid Arthritis
The purpose of this study is to determine whether [18F]FHBG is suitable for use as an imaging probe in cancer or rheumatoid arthritis patients enrolled in cell or gene therapy trials.
- Conditions
- Brain Cancer, Arthritis, Rheumatoid, Central Nervous System Neoplasms, Glioma
- Trial name
- NCT00185848
- Testing
- [18F]FHBG
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Sanjiv Sam Gambhir
Obese Adolescents
Associations Between Physical Activity and Sedentary Behavior Profiles and Carotid Intima-media Thickness in Adolescents With Obesity
Physical activity behaviors are key and modifiable factors of cardiovascular health from childhood. They encompass both physical activity, defined as any bodily movement produced by skeletal muscles that results in energy…
- Trial name
- CARADO (NCT07811115)
- Where
- France
- Volunteers
- 108 people
- Sponsor
- University of Avignon
Appendicitis
Is Acute Appendicitis Still a Clinical Diagnosis?
This study aims to investigate the use of preoperative diagnostic imaging before appendectomy in Denmark and whether it has changed over time during the period from 2000-15.
- Trial name
- NCT04477824
- Testing
- Diagnostic imaging
- Volunteers
- 82,000 people
- Sponsor
- Claus Anders Bertelsen, PhD, MD
Aortic Aneurysm
CO2 Automated Angiographies With Fusion Imaging for Zero- or Near Zero- Contrast FEVAR.
Fenestrated endovascular aneurysm repair (FEVAR) is an established technique used to treat complex aortic aneurysms (TAAAs), with satisfactory early and midterm results.
- Trial name
- NCT06337890
- Testing
- Zero contrast FEVAR
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Bologna
Wound, Wound Infection
Evaluating Surface Area Reduction Using MolecuLight Imaging Device
12-week single-blind, prospective, randomized, controlled, pilot clinical trial assessing The MolecuLight i:X Imaging Device in chronic wounds.
- Trial name
- NCT03181568
- Testing
- MolecuLight i:X™ Imaging Device, Wound care
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Calver Pang
Gastroparesis
Use of EndoFLIP and Manometry Prior to G-POEM
The purpose of this study is to assess physiologic response of therapy in patients with refractory gastroparesis undergoing Gastric per-oral endoscopic myotomy (G-POEM) using endoscopic functional lumen imaging probe (EndoFLIP)…
- Trial name
- NCT04844190
- Testing
- EndoFLIP, Antroduodenal Manometry
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Chronic Pancreatitis
Non-invasive MRI to Quantify the Effect of Secretin on Pancreatic Blood Flow and Perfusion in Healthy Volunteers
Alterations in pancreatic blood have been implicated in pancreatic inflammation and pain. Several modalities have been used to assess pancreatic blood flow although some of these methods are invasive, use ionising radiation or…
- Trial name
- NCT01452217
- Testing
- Secretin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Lungs; Developmental Disorder
Use of Hyperpolarized 129Xe MR Lung Imaging in Infants
Abnormalities of the lungs are common in newborns and can include aspiration or infectious pneumonia, respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD), pulmonary hypertension (PH), congenital diaphragmatic…
- Trial name
- NCT04995562
- Testing
- 129Xe
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Lung Carcinoma, Solitary Pulmonary Nodule
18F-FSPG PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules
This clinical trial compares fluorine F 18 L-glutamate derivative BAY94-9392 (18F-FSPG) positron emission tomography (PET)/computed tomography (CT) to the standard of care fluorodeoxyglucose F-18 (18F-FDG) PET/CT in imaging…
- Conditions
- Lung Carcinoma, Solitary Pulmonary Nodule, Cigarette Smoking Behavior
- Trial name
- NCT02448225
- Testing
- Computed Tomography, fluorodeoxyglucose F-18, Fluorine F 18 L-glutamate Derivative BAY94-9392
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Alcohol Use Disorder, Bipolar Disorder
Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics
The proposed 3-week, double-blind, crossover, proof of concept study aims to manipulate neurochemical dysfunctions characteristic of individuals with co-occurring BD and AUD (i.e., abnormally low prefrontal GABA and glutamate)…
- Trial name
- NCT03220776
- Testing
- N-Acetylcysteine, Gabapentin
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Medical University of South Carolina