Clinical trials: Diagnostic Imaging Utilization
Celiac Disease
Evaluate the Use of Optical Frequency Domain Imaging (OFDI) for Celiac Disease in Children, Adolescents and Young Adults
The goal of this research is to conduct a pilot clinical study to image Celiac disease characteristic mucosal lesions and compare Optical Frequency Domain Imaging (OFDI) images to histologic evaluation in children, adolescents…
- Trial name
- NCT01439035
- Testing
- MGH OFDI Imaging
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Cocaine Use
Pilot Study of Repetitive Transcranial Magnetic Stimulation in Cocaine Craving
Background: Cocaine addiction is often difficult to treat, particularly because exposure to others using cocaine or to pictures of cocaine may evoke cocaine craving and lead a person to resume cocaine use after having quit.
- Trial name
- NCT01222806
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Sponsor
- National Institute on Drug Abuse (NIDA)
Pancreatic Cancer
Preliminary Trial of SNA014 for Pancreatic Cancer
68Ga labeled Claudin 18.2 contrast agent combined with PET/CT for pancreatic cancer
- Trial name
- NCT07597772
- Testing
- 68Ga-NODAGA-SNA006
- Where
- China
- Volunteers
- 12 people
- Sponsor
- SmartNuclide Biopharma
Orthodontics, Malocclusion
The Use of 2D and 3D Imaging Modalities and Its Influence on Diagnosis and Treatment Planning in Orthodontics
Research questions: 1. Will the panoramic images derived from cone beam CT data give better diagnostic ability than conventional panoramic radiographs? 2.
- Conditions
- Orthodontics, Malocclusion, Impacted Tooth, Cephalometry
- Trial name
- NCT01246830
- Testing
- Panoramic radiograph, Cephalometric radiograph, Cone-beam computed tomography (CBCT)
- Where
- 2 sites in Belgium
- Volunteers
- 32 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Prostatic Neoplasms
Dose Escalation For INtraprostatic LEsions
External beam radiotherapy combined with androgen deprivation therapy is a standard treatment option for localized prostate cancer.
- Trial name
- DEFINE (NCT05851547)
- Testing
- Prostate SBRT with Focal Boost, Triptorelin Injection
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- Ottawa Hospital Research Institute
Cannabis Use, Depression
Neural and Psychiatric Consequences of Cannabis Use in Adolescents
The goal of this study is to investigate the effects of cannabis on brain function among adolescents with depression.
- Trial name
- Cann-Teen (NCT06941298)
- Testing
- Neuroimaging Investigation
- Where
- 2 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Miami
Gastric Adenocarcinoma
Diffusion Weighted Magnetic Resonance Imaging for Preoperative Staging in Gastric Adenocarcinoma Patients
Preoperative staging for gastric adenocarcinoma is an important procedure to detect advanced disease stateS for the patients in which the surgery may be unnecessary to perform.
- Trial name
- NCT01794026
- Testing
- diffusion weighted magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Colonoscopy
The Use of Narrow Band Imaging in Screening Colonoscopy
Narrow band imaging (NBI) is an imaging technique that allows a better definition of capillary pattern and improves the contrast between adenomas and the surrounding mucosa.
- Trial name
- NCT00908648
- Testing
- Narrow Band Imaging
- Volunteers
- 206 people
- Sponsor
- Valduce Hospital
Magnetic Resonance Imaging
The Use of a Mock MRI Scanner for Reducing the Use of Anesthesia in Children Undergoing Clinical MRI Scans
Diagnostic Magnetic Resonance (MR) imaging procedures can be stressful for children and parents. Patients must lie still during the procedure to provide diagnostic quality images.
- Trial name
- NCT02630342
- Testing
- Mock MRI scanner, Preparation materials, Child Life Specialist preparation
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Calgary
Rotator Cuff Tear
Sonoelastography to Predict Rotator Cuff Tears
Large-to-massive rotator cuff tears accounts for 30% of all rotator cuff tears. These problems can be solved by surgeries, but only part of them can be completely repaired.
- Trial name
- NCT03682679
- Testing
- Sonoelastography
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
Substance-related Disorders
Women's Treatment and Early Recovery
Approximately 25 million Americans struggle with alcohol or drug problems annually. Abuse of alcohol and drugs is costly to our nation, exacting more than $428 billion in costs related to crime, lost work productivity and health…
- Trial name
- MBRP-W (NCT02977988)
- Testing
- Mindfulness Meditation, Brain and Recovery (B&R)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Southern California
Coronary Artery Disease
CardioPET as PET Imaging Agent to Assess Myocardial Perfusion and Fatty Acid Uptake in Known or Suspected CAD Subjects
The study is designed to evaluate how safe and how well an investigational imaging product CardioPET™ performs as compared to standard approved imaging products in assessing the function of heart muscle in coronary artery disease…
- Trial name
- NCT01826773
- Testing
- CardioPET™
- Where
- 5 sites in Belgium
- Volunteers
- 34 people
- Sponsor
- Fluoropharma, Inc.
Carotid Artery Stenosis, Acute Ischemic Stroke
Acute Stroke of CArotid Artery Bifurcation Origin Treated With Use oF the MicronEt-covered CGUARD (SAFEGUARD-STROKE)
Prospective, single-center, clinical registry of patients with acute stroke of carotid artery bifurcation origin undergoing endovascular treatment using the Micronet-covered CGUARD Stent to seal the culprit lesion under proximal…
- Trial name
- NCT05195658
- Testing
- Thrombectomy and Stenting under neuroprotection
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- John Paul II Hospital, Krakow
Menstrual Cycle, Hormonal Contraception
Oxytocin and Reward Processing in Women
Oxytocin is a hypothalamic neuropeptide that is best known for its peripheral physiological effects in the female organism i.e., uterine contractions during birth.
- Trial name
- NCT06222749
- Testing
- Intranasal oxytocin administration
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- International Research Training Group 2804
Intraoperative Ureter Injury
Dose-escalation Study of a Contrast Agent for Delineation of Urological Anatomy in Minimally Invasive Surgery
The purpose of this clinical trial is to study the safety and efficacy of an investigational imaging agent for delineation/visualization of urologic anatomy in the setting of minimally invasive surgery.
- Trial name
- NCT03106038
- Testing
- Nerindocianine for Injection
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Li-Cor, Inc.
Thyroid Disease
NIRF for Parathyroid Visualization: a Pilot Study
During surgery in which the thyroid is removed (thyroidectomy), the identification of parathyroid glands, that should be saved, can be challenging. Therefore, there is need for accurate intraoperative guidance.
- Trial name
- NCT03012438
- Testing
- NIRF imaging in thyroid surgery
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Maastricht University Medical Center
Alzheimer's Disease, Dementia
Brain Study of Patients With Frontal Lobe Dementia and Parkinsonian Disorders
The Cognitive Neuroscience Section of the National Institute of Neurological Disorders and Stroke proposes to continue its cross-sectional and longitudinal studies of cerebral metabolism in frontal lobe dementias and atypical…
- Conditions
- Alzheimer's Disease, Dementia, Down's Syndrome
- Trial name
- NCT00001178
- Where
- United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Nicotine Dependence
Studying Nicotine Addiction With Transcranial Magnetic Stimulation
Background: Nicotine addiction often makes it difficult to stop smoking. Researchers want to understand the areas of the brain that are important in nicotine addiction.
- Trial name
- NCT01702948
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Pelvic Endometriosis, Endometriosis Outside Pelvis
Prospective Evaluation of Near-infrared Fluorescence Imaging Use as a Supportive Tool in Deep Infiltrating Endometriosis Surgery
The aim of the study is to establish a new and more accurate method to visualize the peritoneal changes caused by endometriosis using Indocyanine Green mediated fluorescence imaging.
- Trial name
- GRE-Endo-2 (NCT03935165)
- Testing
- Indocyanine Green
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Catholic University of the Sacred Heart
Cervical Cancer Stage, Imaging Modalities
The Validity of the Use of Imaging in Cervical Cancer Staging
The study wil aim to investigate the accuracy of imaging in the staging of women diagnosed with cervical cancer
- Trial name
- NCT06487767
- Testing
- Surgery
- Where
- South Africa
- Volunteers
- 100 people
- Sponsor
- University of Pretoria