Clinical trials: Diagnostic Role
Thyroid Nodule
Elastography and FNAC in Thyroid Nodule
Evaluate the accuracy of USE in comparison with FNAC in characterization of solitary thyroid nodule and assessment the risk of malignancy
- Trial name
- NCT05734326
- Testing
- Ultrasound elastography
- Volunteers
- 50 people
- Sponsor
- Assiut University
Wilson Disease
Role for Biochemical Assays and Kayser-Fleischer Rings in Diagnosis of Wilson Disease
The investigators aimed to identify factors associated with symptoms and features of Wilson disease from a large cohort during long-term follow-up
- Trial name
- NCT04965545
- Testing
- low copper diet
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
IMMUNOBULLOUS DISEASES
Trichoscopy in Diagnosis of Immunobollous Diseases
Autoimmune bullous diseases are a variety of skin diseases that are characterized by the presence of bullae or blisters. Most of these diseases are associated with substantial morbidity and mortality.
- Trial name
- NCT03478072
- Testing
- trichoscopy
- Volunteers
- 60 people
- Sponsor
- tasbeeh salah
Chronic Rhinosinusitis Without Nasal Polyps, Chronic Rhinosinusitis (Diagnosis)
Pistacia Lentiscus Oil Nasal Drops for Preventing Recurrence of Chronic Rhinosinusitis
This retrospective, observational, case-control clinical study evaluated the safety and efficacy of nasal drops containing Pistacia lentiscus oil in preventing recurrence of chronic rhinosinusitis during long-term therapy.
- Trial name
- NCT07198607
- Testing
- Pistacia lentiscus Oil Nasal Drops (Bactorinol®), Isotonic Saline Nasal Wash
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Non Enhanced MSCT Abdomen in Diagnosis of Acute Abdomen
Non Enhanced MSCT In Diagnosis of Causes of Acute Abdomen Cases
The acute abdomen is one of the most frequent causes for presentation to the emergency department. Imaging plays an important role for an accurate diagnosis, which in turn diminishes morbidity and mortality Jastaniah and Salih…
- Trial name
- NCT03521011
- Testing
- MSCT
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Uterovaginal Prolapse, Urinary Incontinence
Use of Artificial Intelligence by Urogynecologic Patients
The goal of this clinical trial is to learn about how Urogynecology patients use Artificial Intelligence (AI) Chatbots like ChatGPT, and how it affects healthcare decision making.
- Conditions
- Uterovaginal Prolapse, Urinary Incontinence, Lower Urinary Tract Symptoms
- Trial name
- NCT06481436
- Testing
- Use of ChatGPT
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Hartford Hospital
Subarachnoid Hemorrhage
Neuroinflammation and Bispectral Index After Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is associated with a high mortality and frequently leads to severe disability in survivors caused by cerebral vasospasm and infarction.
- Trial name
- NCT01516671
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Gastroesophageal Reflux
Role of Mucosal Impedance Measurement for the Diagnosis of Gastroesophageal Reflux Disease
Existing current tests for diagnosing GERD are suboptimal because they lack adequate sensitivity or specificity. Upper gastrointestinal endoscopy is highly specific for diagnosing GERD, particularly when erosive esophagitis is…
- Trial name
- NCT06339801
- Testing
- MiVu
- Where
- Argentina
- Volunteers
- 100 people
- Sponsor
- Hospital de Clinicas José de San Martín
Endocarditis Infective
The Role of Polymerase Chain Reaction in the Management of Patients With Infective Endocarditis
The aim of this study is to prospectively investigate the additional diagnostic value of broad range PCR targeting the 16 ribosomal DNA in diagnosis and management of patients with infective endocarditis who are candidate for…
- Trial name
- NCT05791357
- Testing
- PCR (Polymerase Chain Reaction) targeting the 16 ribosomal DNA
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Chronic Pain, Osteo Arthritis Knee
Persistent Pain in Pharmacologically or Surgical Treated Osteoarthritis: Role of Mu-Limpho Marker
The goal of this prospective observational study is to analyze the percentage of expression of B and NK cells expressing Mu opioid receptor on their surface, named Mu-Lympho-Marker (MLM), to measure pain progression in…
- Trial name
- MLM (NCT06637709)
- Where
- Italy
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Abnormal Uterine Bleeding
The Role of TVSG and HS in Determining Endometrial Pathologies
Although hysteroscopy (HS) and transvaginal ultrasonography (TVSG) are methods in the diagnosis of AUB, there is some suspicion about their efficacy.
- Trial name
- NCT03441087
- Testing
- Transvaginal ultrasound, Hysteroscopy
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Congenital Hypothyroidism
Role of Next Generation Sequencing in the Etiological Diagnosis of Permanent Congenital Hypothyroidism With in Situ Thyroid
Retro-prospective, exploratory, single-centre observational study conducted at the Endrocrine-Metabolic Diseases Centre of the Pediatrics Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy.
- Trial name
- NCT06728735
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Progressive Supranuclear Palsy, Cognitive Impairment
Neuropsychological Evaluation for Early Diagnosis of PSP
The aim of this study is to better understand the nature of the cognitive decline in Progressive Supranuclear Palsy, the time of its development and the relation with the other cardinal features of the disease.
- Trial name
- NCT03478124
- Testing
- Cognitive evaluation
- Volunteers
- 112 people
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Acute Diverticulitis, Abdominal Pain
Diagnostic Accuracy of Bedside Ultrasound in Suspected Acute Diverticulitis
Colonic diverticulitis is a common clinical condition in patients presenting to the Emergency Department (ED) with abdominal pain.
- Trial name
- NCT03279588
- Testing
- Bedside Ultrasound
- Where
- 4 sites in Italy
- Volunteers
- 400 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Role of Enteroscopy
Role of Balloon-Assisted Enteroscopy (BAE) in Small Intestinal Disorders
Overall Aim: This study is designed to assess the role of ballon-assisted enteroscopy in the management of obscure small intestinal disorders in a tertiary-care center in Upper Eygpt. Specific objectives: 1.
- Trial name
- NCT04288882
- Testing
- Enteroscopy
- Volunteers
- 80 people
- Sponsor
- Assiut University
Role of Neurofilment in Diagnosis of Multiple Sclerosis
Neurofilament Light Chain as Diagnostic and Prognostic Marker in naïve Multiple Sclerosis Patients
Neurofilament protein detected in the serum appears to be a good marker for the extent of active neurodegeneration. Chitinase may also be a good marker reflecting the degree of astrocyte activation, or damage in active lesions…
- Trial name
- NFLMS (NCT06197841)
- Where
- Egypt
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Assiut University
Lung Cancer
The Role of Endobronchial Needle Aspiration With Rapid On-site Evaluation in the Diagnosis of Central Malignant Lesions
Endobronchial lung cancer tend to manifest in three different patterns. It can present as a bulky, exophytic mass lesion, submucosal infiltration or extrinsic compression from peribronchial disease.
- Trial name
- NCT01456741
- Testing
- EBNA with ROSE, standard EBNA
- Where
- Italy
- Volunteers
- 134 people
- Sponsor
- University of Milan
Exclusive Enteral Nutrition, Ulcerative Colitis
Combined Application of EEN in the Induction of Remission in PUC
The role of exclusive enteral nutrition (EEN) in the induction of remission in pediatric patients with Crohn's disease had been well documented. But the role of EEN in children with Ulcerative Colitis (UC) was not clear.
- Conditions
- Exclusive Enteral Nutrition, Ulcerative Colitis, Children
- Trial name
- NCT04999241
- Testing
- exclusive enteral nutrition, regular food
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Fudan University
Breast Cancer
" Role of Diffusion Weighted Image in the Diagnosis and Follow up of Breast Cancer"
Breast MRI has become an important tool for breast cancer detection and characterization.Contrast enhanced MRI(CE-MRI) is currently the most sensitive detection technique for diagnosis of breast cancer.
- Trial name
- NCT06494865
- Testing
- MRI device
- Volunteers
- 30 people
- Sponsor
- Sohag University
Role of Serum Regucalcin in Diagnosis of HCC
Role of Serum Regucalcin in Diagnosis of Hepatocellular Carcinoma
Although the diagnosis and therapy of HCC have being improved, the poor prognosis still remains. To reduce the mortality and improve the effectiveness of diagnosis and therapy, it is important to detect the protein biomarkers…
- Trial name
- NCT03206866
- Testing
- serum regucalcin antibody
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mansoura University