Clinical trials: Dialysis; Complications
Diabetes
Physical Activity and Functioning in Home Dialysis Patients
This study will compare physical activity levels and physical functioning in patients treated with home dialysis vs. those treated with in-center dialysis.
- Trial name
- NCT01602718
- Testing
- exercise training
- Volunteers
- 120 people
- Sponsor
- University of Utah
Chronic Kidney Disease, Dialysis
The KidneyCARE (Community Access to Research Equity) Study
For chronic kidney disease (CKD), there is a lack of unique and powerful platform for patient engagement, research studies and public health advocacy work.
- Conditions
- Chronic Kidney Disease, Dialysis, Kidney Transplant
- Trial name
- NCT05497518
- Testing
- Observational study - registry
- Where
- United States
- Volunteers
- 50,000 people
- Sponsor
- Tufts Medical Center
End Stage Renal Disease, Chronic Kidney Disease
More Frequent Dialysis (>3 Treatments Per Week)
The study compares the benefits of short daily hemodialysis six days a week, nocturnal (night time) hemodialysis six days a week, every other day and every other night hemodialysis to traditional three days a week…
- Trial name
- MFD (NCT00575497)
- Testing
- More frequent hemodialysis, Conventional Hemodialysis
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Satellite Healthcare
End Stage Renal Disease, Hypotension During Dialysis
Effect of Protein Intake During Hemodialysis on Blood Pressure and Arterial Stiffness Indices
Open label, randomized, cross-over clinical study comparing the acute effect of high versus low protein meals during dialysis on intradialytic blood pressure, 24-hour ambulatory blood pressure and arterial stiffness indices on…
- Conditions
- End Stage Renal Disease, Hypotension During Dialysis, Protein Malnutrition, Arterial Sclerosis
- Trial name
- NCT03947710
- Testing
- High-protein meals, Low- protein meals, No meals
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- Aristotle University Of Thessaloniki
End Stage Renal Disease
Fluid Overload in Peritoneal Dialysis
The objective of this study is to determine the effectiveness of treating peritoneal dialysis (PD) patients with fluid overload by a structured nurse-lead intervention protocol.
- Trial name
- NCT02557347
- Testing
- Aggressive fluid management
- Where
- Hong Kong
- Volunteers
- 102 people
- Sponsor
- Chinese University of Hong Kong
Kidney Failure, Chronic, Peritoneal Dialysis, Continuous Ambulatory
Bisoprolol Versus Cognitive Behavioral Therapy for Stress in Patients on Peritoneal Dialysis
Patients on continuous ambulatory peritoneal dialysis (CAPD) often have chronic stress and anxiety. This pilot study compared two ways to reduce stress in adults on CAPD: cognitive behavioral therapy (CBT) and the beta-blocker…
- Conditions
- Kidney Failure, Chronic, Peritoneal Dialysis, Continuous Ambulatory, Psychological Stress, Anxiety
- Trial name
- NCT07899281
- Testing
- Cognitive behavioral therapy, Bisoprolol
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Universitas Sebelas Maret
End-stage Renal Disease
The Effect of Fructose on Blood Fats in Dialysis Patients and Healthy Volunteers
This study will evaluate how a common dietary sugar (fructose) raises blood fats (triglycerides). We will determine whether the production of fat from fructose is higher in dialysis patients compared to healthy volunteers.
- Trial name
- NCT00234156
- Testing
- oral fructose and high fat diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Chronic Kidney Disease Requiring Chronic Dialysis
Evaluation of Routinely Measured Patient-reported Outcomes in Hemodialysis Care
Patient-reported outcome measures (PROMs) are reports coming directly from patients about how they function or feel in relation to a health condition and its therapy, without interpretation of the patient's responses by a…
- Trial name
- EMPATHY (NCT03535922)
- Testing
- PROMs Assessment
- Where
- 3 sites in Canada
- Volunteers
- 3,977 people
- Sponsor
- University of Alberta
IgAN - IgA Nephropathy
Assessing the Global Burden of IgA Nephropathy (IgAN) in Patients Receiving Hemodialysis: A Real-World Study Using DOPPS Data
This study leverages the global Dialysis Outcomes and Practice Patterns Study (DOPPS) database to generate real-world evidence on the burden of IgAN in patients who progress to kidney failure and require maintenance hemodialysis…
- Trial name
- NCT07607002
- Volunteers
- 70,000 people
- Sponsor
- Arbor Research Collaborative for Health
Chronic Renal Failure
Serum Uremic Toxins and Histological Findings of the Blood Vessels in Dialysis Patients
Patients treated by chronic renal replacement therapy are exposed to cardiovascular problems and suffer from an accelerated and sever atherosclerosis.
- Trial name
- NCT00412139
- Where
- North Macedonia
- Volunteers
- 100 people
- Sponsor
- University of Skopje
Acute Kidney Injury
Pharmacokinetics of Vancomycin in the ICU in Renal Replacement Therapy
This study is an observational analysis that monitors the effect of different dialysis methods on vancomycin levels when patients are critically ill.
- Trial name
- NCT00848809
- Testing
- Blood sample
- Where
- United States
- Sponsor
- Avera McKennan Hospital & University Health Center
Anemia, Chronic Kidney Disease
Safety, PD & PK of Multiple Doses of Peginesatide for Anemia in Chronic Kidney Disease Patients
The purpose of this study was to evaluate the safety, pharmacodynamics (PD), and pharmacokinetics (PK) of multiple subcutaneous injections of peginesatide in participants with chronic kidney disease (CKD) not on dialysis who had…
- Conditions
- Anemia, Chronic Kidney Disease, Chronic Renal Failure
- Trial name
- NCT00228436
- Testing
- peginesatide
- Where
- 13 sites in Poland, United Kingdom
- Volunteers
- 139 people
- Sponsor
- Affymax
Hypotension, End Stage Renal Disease
Pharmacokinetic and Pharmacodynamic Effects of MTR107 in End-Stage Renal Disease (ESRD) Patients
MTR107 effect on blood pressure throught the dialysis procedure and its ability to prevent Intra dialytic Hypotension
- Conditions
- Hypotension, End Stage Renal Disease, Intra Dialytic Hypotension
- Trial name
- NCT00448071
- Testing
- MTR107
- Where
- 2 sites in Israel
- Volunteers
- 12 people
- Sponsor
- Wolfson Medical Center
End-Stage Renal Disease
Vitamin D3 Supplementation in Dialysis Patients
Vitamin D deficiency is highly prevalent among dialysis patients, and has been associated with cardiovascular risk factors such as increased aortic pulse wave velocity, blood pressure, inflammation, and brain natriuretic peptide.
- Trial name
- NCT01312714
- Testing
- Cholecalciferol
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Regional Hospital Holstebro
Peritoneal Dialysis Complication
EMT in Peritoneal Dialysis Patients
Approximately 10-11% of end stage kidney disease patients worldwide utilize peritoneal dialysis (PD) as their method of renal replacement therapy.
- Trial name
- NCT03458819
- Testing
- Isolation of peritoneal mesothelial cells
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Colorado, Denver
Chronic Renal Failure, Anemia
Safety & Efficacy of Pegolsihematide for Treatment of Anemia in Participants on Dialysis
The purpose of this study is to evaluate the safety and efficacy of multiple intravenous doses of pegol-Sihematide in participants with chronic kidney disease (CKD) who are on dialysis.
- Conditions
- Chronic Renal Failure, Anemia, Dialysis
- Trial name
- NCT02586402
- Testing
- pegol-Sihematide, Epoetin Alfa
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Complication of Dialysis, Thrombus Due to Renal Dialysis Device, Implant, or Graft
Cerebral Microembolism During Hemodialysis
There is increasing evidence that renal replacement therapy (= continuous veno-venous hemodialysis) generates cerebral microembolism which is detectable on transcranial Doppler ultrasound.
- Conditions
- Complication of Dialysis, Thrombus Due to Renal Dialysis Device, Implant, or Graft, Cerebral Embolism
- Trial name
- NCT02021045
- Testing
- Renal hemodialysis (Fresenius 2008K, Bad Homburg, Germany)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
ESRD, Disorders Associated With Peritoneal Dialysis
Peritoneal Dialysis Registration System (PERSIST)
Brief Summary: The investigators are registering all PD patients at recruited hospitals and developing a PD database in China. Patients will be followed up every 3 months, and both baseline and follow-up information will be…
- Trial name
- NCT02989298
- Testing
- No intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Sun Yat-sen University
Atrial Fibrillation, End Stage Renal Disease
Trial to Evaluate Anticoagulation Therapy in Hemodialysis Patients With Atrial Fibrillation
This is a prospective, randomized, open-label, blinded end-point evaluation trial. The patient population consists of patients on hemodialysis who have atrial fibrillation (AF) and end-stage renal disease (ESRD) .
- Trial name
- RENAL-AF (NCT02942407)
- Testing
- apixaban, warfarin
- Where
- 58 sites in United States
- Volunteers
- 154 people
- Sponsor
- Christopher Granger, MD
Acute Kidney Injury
Automated Peritoneal Dialysis Versus Intermittent Hemodialysis in Acute Kidney Injury
This is a multi-center randomized clinical trial study. The purpose of this study is to examine safety, feasibility and efficacy of automated peritoneal dialysis as compared with intermittent hemodialysis for AKI patients with…
- Trial name
- SAFE-APD (NCT03598387)
- Testing
- Automated peritoneal dialysis, Intermittent hemodialysis
- Where
- 5 sites in China
- Volunteers
- 100 people
- Sponsor
- Limeng Chen
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