Clinical trials: Dialysis; Complications
Physical Activity, Kidney Diseases
Effects of Exercise and Exercise Counselling in Hemodialysis Patients.
The aim of the study is to determine the effect of functional exercise and training counseling by kinesiotherapist in addition to the basic exercise program of cycling during dialysis on physical performance of dialysis patients.
- Conditions
- Physical Activity, Kidney Diseases, Kidney Failure, Chronic Kidney Diseases
- Trial name
- NCT03334123
- Testing
- Functional training and cycling, Cycling
- Where
- Slovenia
- Volunteers
- 86 people
- Sponsor
- University Medical Centre Ljubljana
End Stage Renal Disease, Cardio-Renal Syndrome
Cardio-Renal Registry
Cardiovascular disease is the leading cause of morbidity and mortality among patients with chronic kidney disease (CKD). Even after adjustment for known cardiovascular risk factors, including diabetes and hypertension, mortality…
- Conditions
- End Stage Renal Disease, Cardio-Renal Syndrome, Myocardial Infarction, Cerebrovascular Accident
- Trial name
- BHCRR (NCT06521801)
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 60,000 people
- Sponsor
- Queen Mary University of London
Heart Failure, Kidney Diseases
Research on Optimal Diagnosis and Treatment of Cardiorenal Syndrome
To estimate the characteristics, pathogenesis, risk factors and intervention measures for different stages of heart and kidney diseases, and to optimize the curative effects of different treatment schemes
- Conditions
- Heart Failure, Kidney Diseases, Kidney Injury, Heart Valve Diseases
- Trial name
- ODT-CRS (NCT05397392)
- Testing
- guideline recommended routine treatment
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Kidney Failure, Inflammation
The Inflammatory Burden in Hemodialysis vs. Peritoneal Dialysis Patients: the Role of Alpha-defensin
The aim of this study is to determine the levels of alpha-defensin throughout the hemodialysis course compared to the levels at the end of a course of peritoneal dialysis, as a reflection of the inflammatory burden.
- Trial name
- NCT03845530
- Testing
- Blood Test
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Hillel Yaffe Medical Center
Chronic Kidney Diseases
Shared Decision-Making and Dialysis Choice
The SDM-DC intervention is designed for patients with kidney failure who must make a decision regarding type of dialysis: haemodialysis or peritoneal dialysis.
- Trial name
- SDM-DC (NCT03868800)
- Testing
- SDM-DC
- Volunteers
- 402 people
- Sponsor
- University of Aarhus
Renal Insufficiency, Chronic, Kidney Failure, Chronic
Effects of a Mindfulness-based Intervention in Stress, Pain and Quality of Life in People Undergoing Hemodialysis
This project has as main objective to evaluate the effects of a Mindfulness-based intervention (MBI) in the reduction of stressors, pain and quality of life of people with chronic kidney disease undergoing hemodialysis (HD).
- Conditions
- Renal Insufficiency, Chronic, Kidney Failure, Chronic, Kidney Diseases, Kidney Insufficiency, Chronic
- Trial name
- NCT04610593
- Testing
- Mindfulness-based Intervention
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Kidney Disease, Peritoneal Dialysis
Treatment of Asymptomatic Fluid Overload in Peritoneal Dialysis Patients
INTRODUCTION Peritoneal dialysis (PD) is a life-saving treatment for end-stage renal disease patients. However, cardiovascular disease remains the major cause of morbidity and mortality in PD patients.
- Trial name
- NCT02168283
- Testing
- treatment arm, Control arm
- Where
- Hong Kong
- Sponsor
- Chinese University of Hong Kong
Dialysis, Fistula
Study of Pain, Anxiety and Complications Related to Cannulation of Arteriovenous (AV) Fistula in Chronic Hemodialysis Patients
A. Pain and other disadvantages of AV fistula cannulation can be limited by using the so-called buttonhole technique. B. Till present in our center catheters with cylindrical points are used for cannulation of AV fistulas with…
- Trial name
- NCT00544492
- Testing
- catheter for AV fistula cannulation
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
End Stage Renal Disease, Peritoneal Dialysis-associated Peritonitis
A Prospective Clinical Study to Assess the Clinical Utility of Turbidity in Patients Using In-Home Peritoneal Dialysis
This study aims to determine if the CloudCath device can detect infections related to peritoneal dialysis (peritonitis) as fast or faster than the current standard methods used by patients and doctors to detect such infections.
- Conditions
- End Stage Renal Disease, Peritoneal Dialysis-associated Peritonitis, Peritonitis
- Trial name
- ACT (NCT05285436)
- Testing
- CloudCath System
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- CloudCath
End Stage Renal Disease
BicMag Study - Improving Mineral Buffering Capacity in Dialysis Patients
The BicMag study is a prospective, randomized, controlled cross-over study that aims to examine the potential additive effect of a dialysate enriched with both bicarbonate and magnesium on mineral buffering capacity in the blood…
- Trial name
- NCT07663279
- Testing
- D-Standard, D-Bic, D-Mag
- Volunteers
- 91 people
- Sponsor
- Elisabethinen Hospital
Undernutrition
Microbiota and Protein-energy Wasting (MIDIWA)
Oral supplementation with branched chain amino acids (BCAA) increases the levels of circulating BCAA, stimulates BCAA uptake in muscles, and decreases amino acid release from muscle, eventually promoting muscle anabolism.
- Trial name
- MIDIWA (NCT02962089)
- Testing
- Branched chain amino acids (BCAA)
- Where
- 5 sites in Switzerland
- Volunteers
- 37 people
- Sponsor
- University Hospital, Geneva
End Stage Renal Disease
Tele-palliative Care in Rural Dialysis Patients
Telemedicine (TM) is an innovative approach that has successfully facilitated palliative care consultations (PCC) in rural settings but not yet in dialysis.
- Trial name
- NCT03744117
- Testing
- Palliative care consultation
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Vermont
Chronic Kidney Disease
Darbepoetin Alfa Once Monthly Dosing Schedule Maintains Hemoglobin Concentration Comparable to Every 2 Weeks Dosing Schedule in Advanced Chronic Kidney Disease Patients Not on Dialysis: A Multicenter, Phase 4 Study
This open-label, multicenter, single-arm phase 4 trial evaluated the efficacy and safety of once-monthly subcutaneous administration of darbepoetin alfa (DARB) compared with biweekly dosing in Korean patients with non-dialysis…
- Trial name
- NCT07025460
- Testing
- darbepoetin alfa
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Gangnam Severance Hospital
Quality of Life, Self Efficacy
Development of Health Monitoring System on Patient's Well Being in Dialysis Context
One of the goals in the Sustainable Development Goals (SDGs) is the availability of a healthy and prosperous life for all ages. This goal mentions health priorities i.e. non-communicable diseases.
- Conditions
- Quality of Life, Self Efficacy, Chronic Kidney Diseases, M-health
- Trial name
- SIKIDI (NCT06306859)
- Testing
- Using m-health for monitoring and education provision, Standard care
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Muhammadiyah Yogyakarta
Cirrhotics With Septic Shock and Acute Kidney Injury
Early Versus Late Sustained Low Efficiency Dialysis in Critically Ill Cirrhotics With Septic Shock and Acute Kidney Injury
Consecutive patients with cirrhosis and septic shock with AKI who give written informed consent will be included in this prospective trial. At baseline NT-Pro BNP, urine N-GAL will be done for all patients.
- Trial name
- NCT02937961
- Testing
- Early SLED, Late SLED
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
End Stage Kidney Disease, Chronic Pain
Pain Reduction Using NEurostimulation Study
This is a 4-year project to see if a small battery-powered, device attached to a headband, that sits on the skin surface and delivers what is a hardly noticeable level of electrical stimulation can reduce pain in patients who…
- Trial name
- PRUNE (NCT05311956)
- Testing
- Active tDCS
- Where
- 2 sites in United States
- Volunteers
- 125 people
- Sponsor
- Weill Medical College of Cornell University
Peritoneal Dialysis Complication, Renal Function Aggravated
Dapagliflozin Delays the Loss of Renal Function in Peritoneal Dialysis Patients
This study aims to explore the role of dagliflozin in preserving the residual renal function(RRF) in peritoneal dialysis (PD) patients.
- Conditions
- Peritoneal Dialysis Complication, Renal Function Aggravated, Sodium-glucose Co-transporter-2 Inhibitors
- Trial name
- NCT06398977
- Testing
- Dapagliflozin
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Sichuan Academy of Medical Sciences
End Stage Renal Disease
Protein-Bound Uremic Retention Solutes in Long Nocturnal Hemodialysis
Although remarkable progress has been made, chronic kidney disease still poses a major burden on both individual patients, as well as on society as a whole.
- Trial name
- NCT00417105
- Testing
- hemodialysis
- Where
- 4 sites in Australia, Belgium
- Volunteers
- 120 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Renal Anemia Associated With Chronic Renal Failure (CRF)
A Study to Investigate the Effect of ASP1517 After Intermittent Oral Dosing in Dialysis Chronic Kidney Disease Patients With Anemia Compared With Darbepoetin as a Reference Drug
This study is to evaluate safety and efficacy of intermittent oral dosing of ASP1517 in dialysis chronic kidney disease patients with anemia.
- Trial name
- NCT01888445
- Testing
- roxadustat, darbepoetin alfa
- Where
- 8 sites in Japan
- Volunteers
- 130 people
- Sponsor
- Astellas Pharma Inc
Chronic Kidney Disease, Dialysis
A Phase 3, Randomized, Double Blind, Placebo-Controlled, Multi-Center, Withdrawal Study of MCI-196 in CKD on Dialysis With Hyperphosphatemia
This is a phase III multi-centre study in three periods: the first period is a phosphate binder washout for 4 weeks, the second period is an open-label, flexible dose titration, the third period is a placebo-controlled withdrawal…
- Conditions
- Chronic Kidney Disease, Dialysis, Hyperphosphatemia
- Trial name
- NCT00506441
- Testing
- MCI-196
- Where
- 39 sites in United States, Puerto Rico
- Volunteers
- 245 people
- Sponsor
- Tanabe Pharma Corporation
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