Clinical trials: Dialysis; Complications
Renal Disease
Acute Physiological Response to Exercise in End Stage Renal Disease
Chronic kidney disease (CKD) affects between 5-10% of the world's population, equating to ~740 million people worldwide. End stage renal disease (ESRD) is the result of a progressive loss of kidney function where the patient…
- Trial name
- PRECISE (NCT03064555)
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Coventry University
Moderate-severe Chronic Kidney Disease Not Treated With Dialysis, Diabetic Kidney Disease, HgbA1c Less Than 8.5
Exercise Study Testing Enhanced Energetics of Mitochondria Video Integrated Delivery of Activity Training in CKD
Skeletal muscle dysfunction (sarcopenia) is an under-recognized target organ complication of CKD with substantial adverse clinical consequences of disability, hospitalization, and death.
- Trial name
- ESTEEM-VIDA (NCT02923063)
- Testing
- Combined Aerobic and Resistance Exercise via videoconferencing
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, Davis
End Stage Renal Disease
Carry Life@ UF System Clinical Study
The Carry Life UF system performs peritoneal ultrafiltration by adding glucose to the low glucose strength (1.36%) peritoneal dialysis fluid which has been instilled into the peritoneal cavity prior to the connection of the…
- Trial name
- NCT05874804
- Testing
- Carry Life UF, 2.27% glucose peritoneal dialysis dwell
- Where
- 11 sites in Italy, Sweden and 1 more
- Volunteers
- 28 people
- Sponsor
- Triomed AB
End Stage Renal Disease
Tele-palliative Care in Rural Dialysis Patients
Telemedicine (TM) is an innovative approach that has successfully facilitated palliative care consultations (PCC) in rural settings but not yet in dialysis.
- Trial name
- NCT03744117
- Testing
- Palliative care consultation
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Vermont
Dialysis, Chronic Renal Failure
A Study to Demonstrate the Safety and Effectiveness of the NIKKISO DBB-EXA ES Hemodialysis Delivery System
The study objective is to verify the safety and effectiveness of the DBB-EXA ES Hemodialysis Delivery System to consistently deliver dialysate of the appropriate quality for infusion.
- Trial name
- HEMO (NCT04655989)
- Testing
- DBB-EXA ES Hemodialysis System
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Nikkiso America, Inc.
Patients With End Stage Renal Disease on Hemodialysis
Effect of Plasma Sodium Concentration on Blood Pressure Regulators During Hemodialysis
Intradialytic hypotension (IDH) is a frequent and serious complication that may occur during hemodialysis treatment. The investigators and others have shown that the Hemocontrol biofeedback system is associated with improved…
- Trial name
- NCT03578510
- Testing
- Hemocontrol hemodialysis, Standard hemodialysis
- Where
- Netherlands
- Volunteers
- 29 people
- Sponsor
- University Medical Center Groningen
End-Stage Kidney Disease
Randomised Evaluation of Sodium Dialysate Levels on Vascular Events
This global study will assess the effect of randomising dialysis sites to one of two default dialysate sodium concentrations in current practice, 140mmol/l and 137mmol/l, on major cardiovascular events and death in patients…
- Trial name
- RESOLVE (NCT02823821)
- Testing
- Default dialysate sodium concentration of 137mmol/l, Default dialysate sodium concentration of 140mmol/l
- Where
- 264 sites in Australia, Canada and 4 more
- Volunteers
- 50,000 people
- Sponsor
- University of Sydney
Chronic Kidney Diseases, Chronic Kidney Failure
SelfWrap-Assisted Arteriovenous Fistulas
This is a single-center, prospective, single-arm clinical study to evaluate the feasibility, safety, and performance of VenoStent's SelfWrap® Bioabsorbable Perivascular Wrap on arteriovenous fistulas (AVFs).
- Conditions
- Chronic Kidney Diseases, Chronic Kidney Failure, End Stage Renal Disease, End Stage Kidney Disease
- Trial name
- SW-AVF (NCT05418816)
- Testing
- SelfWrap Bioabsorbable Perivascular Wrap
- Where
- Paraguay
- Volunteers
- 20 people
- Sponsor
- VenoStent
Peritoneal Dialysis, Chronic Kidney Disease
Study of Safety and Efficacy of Renagel® Compared With Calcium Acetate in Patients With Peritoneal Dialysis
The purpose of this study is to demonstrate that sevelamer hydrochloride is non-inferior to calcium acetate for the treatment of hyperphosphataemia in patients receiving peritoneal dialysis.
- Trial name
- NCT00196755
- Testing
- Sevelamer Hydrochloride (Renagel®), Calcium acetate (PhosLo® )
- Where
- 17 sites in Belgium, Denmark and 5 more
- Volunteers
- 138 people
- Sponsor
- Genzyme, a Sanofi Company
End-stage Renal Disease
End-Stage Renal Disease Intra-dialysis Lifestyle Education Study
The purpose of this study is to compare the effects of intra-dialysis yoga to an educational program among patients with end-stage renal disease.
- Trial name
- END-IDLE (NCT02361268)
- Testing
- Intradialysis-yoga, Educational program
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Vanderbilt University Medical Center
Anemia in Chronic Kidney Disease in Non-dialysis Patients
Roxadustat in the Treatment of Anemia in Chronic Kidney Disease (CKD) Patients, Not on Dialysis, in Comparison to Darbepoetin Alfa
The primary objective of this study was to evaluate the efficacy of roxadustat compared to darbepoetin alfa in the treatment of anemia in nondialysis-dependent chronic kidney disease (NDD CKD) participants.
- Trial name
- Dolomites (NCT02021318)
- Testing
- Roxadustat, Darbepoetin alfa
- Where
- 125 sites in Austria, Belarus and 24 more
- Volunteers
- 616 people
- Sponsor
- Astellas Pharma Europe B.V.
Anaemia
Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-in Incident Dialysis (ASCEND-ID)
The purpose of this multi-center study is to evaluate the efficacy and safety of daprodustat in subjects with anemia associated with CKD.
- Trial name
- NCT03029208
- Testing
- Daprodustat, Darbepoetin alfa, Iron therapy
- Where
- 111 sites in United States, Argentina and 13 more
- Volunteers
- 312 people
- Sponsor
- GlaxoSmithKline
Dialysis Related Complication, Dialysis Hypotension
Expanded Hemodialysis Versus Online Hemodiafiltration
Conventional hemodialysis (HD) is essential for the treatment of end-stage renal disease (ESRD) patients, by reducing serum concentration of uremic toxins and correcting fluid overload.
- Conditions
- Dialysis Related Complication, Dialysis Hypotension, Hemodialysis-Induced Symptom
- Trial name
- NCT03274518
- Testing
- Expanded Hemodialysis, Online Hemodiafiltration
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- University of Sao Paulo
End-stage Renal Disease
The Feasibility and Safety of an Intradialytic Exercise Program: DIALY-SIZE
The primary aim of this pilot study is to evaluate the feasibility and safety of four different types of intradialytic exercise (exercise performed during dialysis) programs: resistance, aerobic, combined resistance and aerobic…
- Trial name
- NCT02234232
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of Alberta
Dialysis, Anemia
Study of Roxadustat (FG-4592) to Correct Anemia in Newly Initiated Dialysis Participants Not on Erythropoiesis-Stimulating Agent Treatment
The purpose of this study is to evaluate efficacy and safety of roxadustat in the correction of anemia in participants with end-stage renal disease who recently started dialysis.
- Trial name
- NCT01414075
- Testing
- Roxadustat, Oral Iron, IV Iron
- Where
- 7 sites in United States, Hong Kong and 2 more
- Volunteers
- 60 people
- Sponsor
- Kyntra Bio
Anemia, Renal Failure
Heme Iron Polypeptide for Iron Deficiency Anemia in Chronic Renal Failure
The purpose of this study is to determine if oral Heme Iron Polypeptide is as effective as intravenous (IV) iron sucrose in the treatment of iron-deficiency anemia for patients with chronic kidney disease.
- Trial name
- NCT00318812
- Testing
- Heme Iron Polypeptide (Proferrin), Iron sucrose (Venofer)
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Ottawa Hospital Research Institute
Uremia, End Stage Renal Disease on Dialysis
Independent Effects of Visceral Adipose Volume and Density on Patient Survival in Peritoneal Dialysis
It was VAT volume predict patient outcome, while VAT density predicted baseline membrane function in PD patients and reflected peritoneal vascular density and local inflammation status.
- Trial name
- NCT07086430
- Volunteers
- 358 people
- Sponsor
- RenJi Hospital
Chronic Kidney Diseases, Cardiovascular Risk Factors
Cardiovascular Risk Factors and Physical Activity in Chronic Kidney Patients on Peritoneal Dialysis
The objective of this study was to examine the association between cardiovascular risk factors and physical activity parameters in patients with chronic kidney disease who are treated with peritoneal dialysis.
- Conditions
- Chronic Kidney Diseases, Cardiovascular Risk Factors, Arterial Stiffness, Physical Activity
- Trial name
- NCT07041554
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Dokuz Eylul University
Chronic Kidney Failure, End-Stage Kidney Disease
Traditional Chinese Medicine (TCM) Colon Dialysis Treats Non-dialysis End-Stage Kidney Disease
This study evaluates the clinical efficacy and study the therapeutic mechanism of a kind of traditional Chinese medicine colonic dialysis on Chronic kidney disease (CKD) 5 without blood dialysis therapy in adults.
- Trial name
- NCT03142529
- Testing
- colon lotion
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Pang Peng
End Stage Renal Disease
24 Hour Use of the Wearable Artificial Kidney
This is a prospective, interventional study designed to provide preliminary data on the human use of the WAK. Up to 10 subjects currently receiving intermittent hemodialysis (HD) treatment three times per week for end-stage renal…
- Trial name
- WAK US 1 (NCT02280005)
- Testing
- WAK Treatment
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Blood Purification Technologies, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.