Clinical trials: Dialysis
Peritoneal Dialysis-associated Peritonitis
Improved Diagnosis of Peritoneal Dialysis Peritonitis by Calorimetry
The purpose of this study is to analyze whether calorimetry compared to conventional methods (i.e.blood culture systems)is superior to diagnose peritoneal dialysis related peritonitis.
- Trial name
- NCT00801775
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- University Hospital, Basel, Switzerland
Hemodialysis
STUDY OF GLUCOSE IN DIALYSIS WATER WITH REGARD TO BLOOD PRESSURE AND QUALITY OF LIFE
We wanted to test the hypotheses that blood pressure level was lower, that the variability of blood pressure and blood glucose was reduced, and that quality of life was improved when glucose was added to the dialysis fluid.
- Trial name
- NCT00278057
- Testing
- dialysisis with and without glucose in the dialysis
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Regional Hospital Holstebro
Chronic Renal Failure, Hemodialysis Treatment, Protein-energy Wasting
Effect of Intradialytic Physical ACTIvity in Addition to a NUTritional Support on Protein Energy Wasting and Physical Functioning in Chronic Hemodialysis Patients ("ACTINUT" Study)
Sedentary behavior and protein-energy wasting (PEW) are well known risk factors of adverse outcome and low quality of life in chronic renal failure patients treated by dialysis.
- Trial name
- ACTINUT (NCT01813851)
- Testing
- Exercise training in addition to nutritional support
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- Nantes University Hospital
Renal Failure, Albumin; Double
High-Protein Food Snack for Dialysis Patients
The study team aims to provide a food snack that is high in protein (30 g) for two weeks each month (6 treatments per patient per month) for 6 consecutive months, post-dialysis treatment, to in-center hemodialysis patients of all…
- Conditions
- Renal Failure, Albumin; Double, Diet Habit
- Trial name
- NCT04134377
- Testing
- Protein Food Snack
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Florida
Anemia
A Study of Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) for the Treatment of Chronic Renal Anemia in Participants With Diabetic Nephropathy
This single arm, open label study will assess the efficacy, safety and tolerability of methoxy polyethylene glycol-epoetin beta for the treatment of chronic renal anemia in participants with chronic kidney disease (CKD) secondary…
- Trial name
- NCT01191983
- Testing
- Methoxy polyethylene glycol-epoetin beta [Mircera]
- Where
- 14 sites in India
- Volunteers
- 102 people
- Sponsor
- Hoffmann-La Roche
Dialysis Patients, Hypertension
Carotid Intima-media Thickness in Dialysis Patients and Traditional Risk Factors
Cardiovascular disease (CVD) is the leading cause of mortality in hemodialysis (HD) patients. Carotid intima-media thickness (CIMT) is a validated surrogate marker for atherosclerosis.
- Conditions
- Dialysis Patients, Hypertension, Atherosclerosis
- Trial name
- NCT07558239
- Testing
- Ultrasound measurements of carotid intima- media thickness
- Volunteers
- 100 people
- Sponsor
- Minia University
Renal Dialysis, Kidney Failure, Chronic
Quality of Life of Frail Aged Patients in Incremental Hemodialysis
End stage renal disease (ESRD) is a major public health problem. The dialysis population is aging. As a result we observe a high prevalence of frailty among dialysis patients (ranges from 3 to 10 fold higher than in the…
- Conditions
- Renal Dialysis, Kidney Failure, Chronic, Frailty
- Trial name
- Qualifragilys (NCT03782519)
- Testing
- Dialysis frequency reduction, Frailty diagnosis
- Where
- France
- Volunteers
- 783 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
End Stage Renal Disease (ESRD), Chronic Kidney Disease (CKD)
Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM)
This is a 2-year, randomized, multicenter, open-label, 2-arm study evaluating the graft function of everolimus and reduced CNI versus MPA and standard CNI in adult de novo renal transplant recipients.
- Conditions
- End Stage Renal Disease (ESRD), Chronic Kidney Disease (CKD), Hemodialysis, Renal Replacement Therapy
- Trial name
- TRANSFORM (NCT01950819)
- Testing
- Induction therapy, Corticosteroids, EVR+rCNI
- Where
- 184 sites in United States, Argentina and 40 more
- Volunteers
- 2,037 people
- Sponsor
- Novartis Pharmaceuticals
Anemia
Safety and Tolerability of a Single Dose of FCM vs. Standard of Care in Treating Iron Deficiency Anemia
The objective of this study is to evaluate the safety of FCM in patients with anemia who are not dialysis dependent
- Trial name
- NCT00704353
- Testing
- Ferric Carboxymaltose, Standard Medical Care (SMC)
- Where
- United States
- Volunteers
- 735 people
- Sponsor
- American Regent, Inc.
End Stage Renal Disease, Depression
Cognitive Behavioral Treatment of Depression in ESRD Patients on Dialysis
Depression is second in frequency only to hypertension as a comorbid condition for End Stage Renal Disease (ESRD) patients. The presence of depression has been linked to lower quality of life, more medical comorbidities and…
- Trial name
- NCT00618475
- Testing
- Cognitive behavioral therapy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Kidney Disease Requiring Chronic Dialysis
Morphological Changes of the Brain by MRI in Chronic Kidney Disease
The purpose of this study is to describe brain´s morphological changes induced by chronic kidney disease (CKD) in advanced stages (stages 4 and 5 defined by KDOQI guidelines) and also by haemodialysis using MRI.
- Trial name
- KIDBRAIN (NCT02827253)
- Testing
- MRI
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Anemia, End Stage Renal Disease
Lexaptepid Pegol (NOX-H94) in ESA-hyporesponsive Anemia in Dialysis Patients
Dialysis patients regularly suffer from anemia which may be caused by various contributing factors, alone or in combination, including blood loss, low erythropoietin and iron sequestration.
- Trial name
- NCT02079896
- Testing
- Lexaptepid pegol (NOX-H94)
- Where
- 10 sites in Germany, Italy and 1 more
- Volunteers
- 33 people
- Sponsor
- TME Pharma AG
Dialysis Access Malfunction
Recurrent Stenoses in Arteriovenous Fistula (AVF) for Dialysis Access: CuttIng ballooN angioplaSTy Combined wITh Paclitaxel drUg coaTed Balloon Angioplasty, an observatIONal Clinical Study
To determine if cutting balloon angioplasty combined with DEB angioplasty provides a higher primary patency after treatment of recurrent stenoses compared with cutting balloon angioplasty or angioplasty using DEB alone in the…
- Trial name
- INSTITUTION (NCT05018962)
- Testing
- Cutting balloon followed by paclitaxel coated balloon
- Where
- Singapore
- Volunteers
- 44 people
- Sponsor
- Singapore General Hospital
Acute Kidney Injury, Dialysis; Complications
Epidemiology of In-hospital Acute Kidney Injury
Retrospective observational study to investigate acute kidney injury (AKI) epidemiology and outcomes in patients hospitalized in University Hospital San Martino, Genova, Italy.
- Conditions
- Acute Kidney Injury, Dialysis; Complications, Chronic Kidney Diseases
- Trial name
- GENAKI (NCT05151003)
- Testing
- Data collection
- Where
- Italy
- Volunteers
- 60,000 people
- Sponsor
- Universita degli Studi di Genova
Kidney Disease, Chronic, Diabetes
Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis
This study aims to determine if GLP1RA is safe and tolerable in maintenance dialysis population, adherence, and feasibility of a larger definitive cardiovascular outcome trial in this population.
- Conditions
- Kidney Disease, Chronic, Diabetes, Dialysis, End Stage Kidney Disease (ESRD)
- Trial name
- GUARD-1 (NCT07017270)
- Testing
- Semaglutide Pen
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Unity Health Toronto
Inflammation, Chronic Kidney Disease
Role of Prohepcidin in Uremic Patients
The investigators aimed to study the effect of prohepcidin levels on hematologic parameters and inflammatory markers in non-diabetic uremic patients.
- Trial name
- NCT01735773
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Treatment Adherence and Compliance, Effectiveness
Educational Intervention and Adherence
quasi-experimental, parallel study, with the objective of evaluating the effectiveness of an educational nursing intervention supported by ICTs, for the improvement of therapeutic adherence in people undergoing hemodialysis…
- Conditions
- Treatment Adherence and Compliance, Effectiveness, Renal Dialysis, Nurse's Role
- Trial name
- Hemodialysis (NCT06742827)
- Testing
- educational intervention based on information and communication technologies.
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Universidad de Antioquia
Renal Failure, Chronic
Glucose in Dialysis Water in Non-diabetics
The purposes are 1. to measure the effect of dialysis with glucose on blood pressure, pulse rate, plasma concentration of glucose, plasma concentrations of glucagon, growth hormone, renin, angiotensin II, endothelin and body…
- Trial name
- NCT00439023
- Testing
- dialysis with glucose in dialysis water
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Regional Hospital Holstebro
ESRD
Glucose Metabolism During Hemodialysis
Disturbed glucose metabolism is a common feature of patients with end-stage renal disease (ESRD). Several hormones responsible of a stable blood glucose including insulin, glucagon, and the gastrointestinal insulinotropic…
- Trial name
- NCT01800188
- Testing
- Hemodialysis, Hemodiafiltration, Meal test
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Bo Feldt-Rasmussen
Dialysis; Complications, Vascular Access Complication
Comparison of Three Types of Distal Arteriovenous Fistulas: SBAVF, RCAVF, and RCAVF With Venous Branch Patch.
This study aims to determine which type of distal arteriovenous fistula (SBAVF, RCAVF, and RCAVF with venous branch patch) is most clinically favorable.
- Trial name
- NCT06550479
- Testing
- AVF
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Wroclaw Medical University