Clinical trials: Dialysis
Diabetes, Diabetes Mellitus, Type 1
Evaluation of Accuracy of Continuous Glucose Monitoring (CGM) in Patients With End Stage Renal Disease (ESRD) on Intermittent Hemodialysis (iHD).
Recent advances in continuous glucose monitors (CGMs) and availability of commercial CGM products to patients with type 1 and type 2 diabetes has made the use of CGM more widespread.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT04094064
- Testing
- Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Peritoneal Dialysis Complication
EMT in Peritoneal Dialysis Patients
Approximately 10-11% of end stage kidney disease patients worldwide utilize peritoneal dialysis (PD) as their method of renal replacement therapy.
- Trial name
- NCT03458819
- Testing
- Isolation of peritoneal mesothelial cells
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Colorado, Denver
Intradialytic Hypotension, Intensive Care Unit ICU
Using a Hypotension Prediction Index to Prevent Low Blood Pressure During Dialysis in ICU Patients
This single-center, crossover randomized controlled trial (HyPIR-ICU) investigates whether a Hypotension Prediction Index (HPI)-guided management strategy can reduce intradialytic hypotension (IDH) during prolonged intermittent…
- Conditions
- Intradialytic Hypotension, Intensive Care Unit ICU, Hemodialysis Patients
- Trial name
- HyPIR-ICU (NCT07179705)
- Testing
- Hypotensive prediction index, Standard of care monitoring
- Where
- Thailand
- Volunteers
- 46 people
- Sponsor
- Chulalongkorn University
Chronic Renal Failure
Clinical Study on Optimised Removal of Protein-bound Uremic Toxins With Convective Dialysis Treatment.
Patients will be treated with hemodiafiltration (HDF) in postdilution mode, as a control therapy, during 9 weeks. During week 5 the 1st intervention treatment, predilution hemofiltration (HF) or predilution HDF, will be performed…
- Trial name
- NCT00337831
- Testing
- Performance of predilution hemofiltration, predilution hemodiafiltration or postdilution hemodiafiltration
- Where
- Belgium
- Volunteers
- 17 people
- Sponsor
- University Hospital, Ghent
Renal Failure, Renal Insufficiency
H-Guard Pilot Safety Evaluation in Haemodialysis Patients
The purpose of this research study is to find out the safety and effectiveness of a new medical device called H-Guard. During this research study, participants will receive the standard of care haemodialysis treatment, as decided…
- Conditions
- Renal Failure, Renal Insufficiency, Renal Disease
- Trial name
- NCT06070337
- Testing
- H-Guard
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Invizius Limited
Chronic Kidney Disease Requiring Hemodialysis, End Stage Renal Disease (ESRD)
Early Feasibility Study of the Velocity™ Percutaneous Arterio-Venous Fistula System for Creating Hemodialysis Vascular Access
The Velocity Percutaneous Arterio-Venous System is a minimally invasive method of creating hemodialysis vascular access. The study aims to understand clinical efficacy and initial clinical safety data of the device.
- Trial name
- VENOS-2 (NCT06712251)
- Testing
- Velocity pAVF System
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- Venova Medical
AKI, AKI - Acute Kidney Injury
Outpatient Recovery From Acute Kidney Injury Requiring Dialysis - 2
Providing additional information to patients with acute kidney injury who continue dialysis after hospital discharge and to the accepting kidney doctor (nephrologist) who manages their dialysis may be feasible and beneficial.
- Conditions
- AKI, AKI - Acute Kidney Injury, Dialysis Patients
- Trial name
- ORKID-2 (NCT07106151)
- Testing
- Transmission of additional AKI-D recovery information, No additional AKI-D recovery information
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Renal Failure
Effects of Spironolactone in Dialysis
Several studies indicate that chronic kidney disease patients give a high cardiovascular risk and have an intrinsic relationship with hypertension and cardiomyopathy: characterized by left ventricular hypertrophy and interstitial…
- Trial name
- NCT01128101
- Testing
- Spironolactone
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Renal Insufficiency
Clinical Assessment of a New Catheter Surface Coating With Antimicrobial Properties
The study investigates the efficacy of a catheter with antibacterial surface coating in preventing central venous catheter related infection and the effect of an intensive hygiene and catheter care education of the nursing staff…
- Trial name
- NCT00621712
- Testing
- GamCath® central venous catheter, GamCath Dolphin® Protect central venous catheter
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Vantive Health LLC
Dialysis; Complications
Effect of Sodium and UF Profiling on Dialysis
The aim of this study is to evaluate the effects of sodium and UF profiling on hemodynamic stability, interdialytic weight gain, and intradialytic complications
- Trial name
- NCT06213129
- Testing
- Na and ultrafiltration profiling
- Volunteers
- 30 people
- Sponsor
- Assiut University
Cardio-renal Syndrome
Ultrafiltration Versus Medical Therapies in the Management of the Cardio Renal Syndrome
Type 2 cardio renal syndrome is defined by the occurrence or the exacerbation of a kidney failure induced by a chronic heart failure.
- Trial name
- UF-CARE (NCT02846337)
- Testing
- ULTRAFILTRATION, ENHANCED MEDICAL TREATMENT
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Hospices Civils de Lyon
Hemodialysis, Hypercholesterolemia
Malnutrition and Inflammation in Dialysis Patients in Taiwan
According to the reports of the United States Renal Data System (USRDS), there is a 25% annual mortality rate with nearly 50% of all reported maintenance hemodialysis (HD) patient deaths attributed to atherosclerosis-related…
- Conditions
- Hemodialysis, Hypercholesterolemia, Malnutrition, Inflammation
- Trial name
- NCT00173823
- Where
- Taiwan
- Volunteers
- 1,500 people
- Sponsor
- National Taiwan University Hospital
Chronic Kidney Diseases, Iron Deficiency Anemia
KRX-0502 (Ferric Citrate) in Subjects With NDD-CKD and IDA (The COMPASS Trial)
The objectives of this study are to assess the long-term efficacy and safety of different dose regimens of KRX-0502 in the treatment of iron deficiency anemia (IDA) in adult subjects with non-dialysis dependent chronic kidney…
- Trial name
- COMPASS (NCT03236246)
- Testing
- KRX-0502
- Where
- 28 sites in United States
- Volunteers
- 206 people
- Sponsor
- Keryx Biopharmaceuticals
End Stage Chronic Renal Failure
Study of Patient Preferences in Dialysis Treatment Choice: a Discrete Choice Experiment
Background Compared to in-center dialysis, home dialysis is associated with better quality of life and lower healthcare system costs. However, barriers remain to its wider adoption.
- Trial name
- PREFDOM (NCT07535320)
- Testing
- Questionnaire
- Where
- 2 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Caen
Acute Kidney Injury
Study of Suramin in Subjects With Furosemide-Resistant AKI
This is a prospective, double-blind, randomized, placebo-controlled study to assess the effects of suramin as a potential treatment option to prevent subjects with AKI from progressing to Kidney Disease Improving Global Outcomes…
- Trial name
- NCT04496596
- Testing
- Suramin
- Where
- 12 sites in United States
- Volunteers
- 68 people
- Sponsor
- Rediscovery Life Sciences
Liver Cirrhosis
Sustained Low Efficiency Dialysis Versus Continuous Renal Replacement Therapy for Acute Kidney Injury in Critically Ill Cirrhotics
The current prospective pliot randomized controlled trial has been designed to demonstrate non-inferiority of sustained low efficiency dialysis (SLED) when compared to continuous renal replacement therapy in managing AKI in…
- Trial name
- NCT04494542
- Testing
- Sustained Low Efficiency Dialysis (SLED), Continuous Renal Replacement Therapy
- Where
- India
- Volunteers
- 62 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
End Stage Renal Disease, Pruritus
DIalysis Symptom COntrol-Pruritus Outcome Trial
The purpose of this study is to test whether or not a medication called nabilone, which is a synthetic (non-natural) medication derived from cannabis, compared to placebo improves symptoms of itch in hemodialysis as measured by…
- Trial name
- DISCO-POT (NCT05180968)
- Testing
- Nabilone 0.5 MG Oral Capsule
- Where
- 2 sites in Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
End Stage Renal Failure on Dialysis, Body Fluid Retention
Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal on Hemodialysis
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 …
- Conditions
- End Stage Renal Failure on Dialysis, Body Fluid Retention, Impedance, Cardiac Output, Low
- Trial name
- CI/HD (NCT02485782)
- Testing
- CardioScreen 1000 - Haemodynamic Measurement System, Medis, BCM- Body Composition Monitor, Fresenius Medical Care, SCHILLER, BR-102 plus, Ambulatory Blood Pressure Monitoring System
- Where
- Poland
- Volunteers
- 48 people
- Sponsor
- Medical University of Warsaw
Hepatitis C Virus Infection, Response to Therapy of
Clinical Trial to eLiminate HCV-infection in Treatment-naïve, Renally Impaired EgyptiAn Patients on Renal Dialysis, With Chronic Hepatitis C Genotype 4
Primary Efficacy Objective -To assess whether a 12-week treatment course with oral 50 mg elbasvir plus 100 mg grazoprevir given in a single daily dose to treatment-naïve patients with end-stage renal disease (ESRD) and infected…
- Trial name
- CLEAR-C4 (NCT03381859)
- Testing
- Elbasvir/Grazoprevir 50 MG-100 MG Oral Tablet [ZEPATIER]
- Where
- Egypt
- Sponsor
- University of Maryland, Baltimore
Treatment Adherence and Compliance, Effectiveness
Educational Intervention and Adherence
quasi-experimental, parallel study, with the objective of evaluating the effectiveness of an educational nursing intervention supported by ICTs, for the improvement of therapeutic adherence in people undergoing hemodialysis…
- Conditions
- Treatment Adherence and Compliance, Effectiveness, Renal Dialysis, Nurse's Role
- Trial name
- Hemodialysis (NCT06742827)
- Testing
- educational intervention based on information and communication technologies.
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Universidad de Antioquia